apoptosis vs necrosis

apoptosis

Definitions

noun

  1. a type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animal's survival

Examples

Conclusion MTBE′s carcinogenicity to animals may relate to induction of cell proliferation and inhibition of cell apoptosis.

AIM:To observe the effect of resveratrol, reactivator of silent information regulator 2 (SIR2), on myocardial cell apoptosis induced by ischemia and reperfusion in rats and SIR2 expression.

Result: Methylprednisolone inhibited the activity of neural stem cells in vitro, and also promoted apoptosis of neural stem cells.

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necrosis

Definitions

noun

  1. the localized death of living cells (as from infection or the interruption of blood supply)

Examples

Lefebvre V, Peeters-Joris C, Vaes G. Modulation by interleukin 1 and tumor necrosis factor alpha of production of collagenase, tissue inhibitor of metalloproteinases and collagen types in differentiated and dedifferentiated articular chondrocytes.

BDC is currently conducting a Phase two placebo-controlled proof of concept study with the tumor necrosis factor (TNF) inhibitor, etanercept, epidurally administered to a minimum of 40 patients with sciatica.

By convention, the terms \'aseptic\ 'or \'avascular\' necrosis have been applied to areas of juxtaarticular involvement and the term bone infarct is usually applied to metaphyseal or diaphyseal involvement.

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