How To Use tumor suppressor gene In A Sentence
- These observations suggest that the mutated tyrosine phosphatases are tumor suppressor genes, regulating cellular pathways that may be amenable to therapeutic intervention.
- Ptch is the gene responsible for NBCCS.9,10 However, to our knowledge no studies have examined OKCs for DNA damage in other known tumor suppressor genes or tumor oncogenes.
- Progen and its collaborators have focused their research on an enzyme known as lysine specific demethylase 1 (LSD1), which contributes to the silencing of important tumor suppressor genes. StreetInsider.com News Articles
- Objective To study the relationship between tumor suppressor gene PTEN , P 16, P 15 and primary cervical carcinomas.
- During these events, cells will carry multiple genetic alterations including inactivation of tumor suppressor genes and activation of oncogenes that will help the escape of the cells from normal growth control.
- A broad panel of 14 tumor suppressor genes, both associated and unassociated with neoplasia, were selected for microdissection-based genotyping.
- This difference indicates a striking increase in selection against nonsynonymous substitutions in oncogenes and tumor suppressor genes.
- Thus, most hereditary cancer syndromes are the result of inherited mutations in tumor suppressor genes rather than oncogenes.
- The FeLV-induced tumors are thought to be caused, at least in part, by somatically acquired insertional mutagenesis in which the integrated provirus may activate a proto-oncogene or disrupt a tumor suppressor gene.
- Interaction between metabolites of chemical carcinogens, such as polycyclic aromatic hydrocarbons, and DNA can cause mutation in oncogenes and tumor suppressor genes which is believed to initiate the carcinogenic process.
