[ US /ˈtɛɫəmiɹ/ ]
either (free) end of a eukaryotic chromosome
telomeres act as caps to keep the sticky ends of chromosomes from randomly clumping together
How To Use telomere In A Sentence
- In normal somatic cells, the telomeres shorten with replicative age, and telomerase is not detected.
- All transfectants lacked detectable telomerase activity, showed progressive telomere shortening and ultimately arrested and died.
- And, we realized the old truism from the original cytogenetics which was that the telomere is really important for protecting ends and, as you might expect, the cell actually devotes all sorts of machinery to make sure that never goes wrong, or goes wrong as little as possible. Elizabeth H. Blackburn - Interview
- Telomeres are near the nuclear envelope; the two 5S rDNA loci remain unpaired.
- Which chromosomes have the shortest telomeres depends only on telomere length in the original parent mice.
- The region neighboring the telomeres also appears to be rich in duplicated regions.
- In nature, a chromosome can be lengthened by the enzyme telomerase, which adds new TTAGGG sequences to the end of the telomere.
- Telomere locates on the terminal of DNA containing repeat DNA sequence.
- Can telomere maintenance be eliminated effectively ( and selectively ) enough by more tractable approaches?
- Researchers estimate that telomere maintenance activity occurs in about 90 % of human cancers.