scrapie

[ UK /skɹˈæpa‍ɪ/ ]
NOUN
  1. a fatal disease of sheep characterized by chronic itching and loss of muscular control and progressive degeneration of the central nervous system
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How To Use scrapie In A Sentence

  • In the virino model, the host protein protects the scrapie agent nucleic acid from degradation and prevents the host raising an immune response, since the protein/nucleic acid complex is seen as ‘self’.
  • Pathologists have identified degenerative changes in brain samples of diseased cattle similar to scrapie-infected sheep brain.
  • Scrapie is still common in sheep, but doesn't seem to strike people.
  • Extensive search through the model parameter space produced only long-term scrapie persistence for ε3 ≥ 0.01. PLoS ONE Alerts: New Articles
  • Sheep are susceptible to their own brain wasting disease called scrapie, but this disease has never been shown to be transmissible to humans.
  • Healthy sheep inoculated with tissue from animals with scrapie took years to develop symptoms, far longer than for any other known infection.
  • Many rams have already been genotyped for their ability to pass on resistance to scrapie.
  • Although well-established in scrapie and, more recently, in BSE, comparatively little is known about the possibility of prion strains in chronic wasting disease (CWD), a disease affecting free ranging and captive cervids, primarily in North America. CWD Worse Than Ever In Wisconsin Counties
  • For many years after their discovery as the agents of some rare neurodegenerative diseases in mammals, such as scrapie in sheep and human Creutzfeldt-Jakob disease and kuru, prions have remained a truly esoteric research topic.
  • I didn't drive it particularly well, so I was a little 'scrapie' on the front nine," he said. Columnist: Keith Groller
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