How To Use Refractory In A Sentence

Very high dosage fluphenazine for nonchronic treatment-refractory patients. The Neuropsychiatric Guide to Modern Everyday Psychiatry
That enviably resilient Bayesian model has been cracked, in the eyes of many philosophers, by such refractory phenomena as akrasia or ‘weakness of will.’
In WS, the three PAI loci are highly refractory to cleavage by either HpaII or MspI, diagnostic of dense CG and CCG methylation of the recognition site.
They are generally so refractory, self-conceited, obstinate, so firmly addicted to that religion in which they have been bred and brought up, that no persuasion, no terror, no persecution, can divert them. Anatomy of Melancholy
In refractory cases, monounsaturated fats may replace carbohydrates, but weight and lipid profile should be closely monitored.

This, in turn, renders cells refractory to subsequent infection by the same or other viruses that use the CD4 receptor for entry; thus creating a state of super-infection immunity.
Does the downregulation of the FGF23 signaling pathway in hyperplastic parathyroid glands contribute to refractory secondary hyperparathyroidism in CKD patients Naturejobs - All Jobs
* The effect of this little bit of science may be thus stated -- Men for two years had been punished as refractory for not making all day two thousand revolutions per hour of a 15 lb. crank, when all the while it was a _45 lb. crank_ they had been vainly struggling against all day. It Is Never Too Late to Mend
ROME -- Long-term gout patients should not be considered "refractory" -- and clinicians should not treat them as such -- until uric crystals are dissolved to the point that flares of pain are prevented, a researcher said here. Medicaid and Medicare
Fumed silica is used as a filler in the cement and refractory materials industries, as well as in heat insulation and filling material for synthetic rubbers, polymers and grouts. Silicon
Because bioreductive drugs are activated to form highly effective cytotoxins under hypoxic conditions, they can be used to inactivate hypoxic tumor cells that are refractory to the direct cytotoxicity of hypericin-PDT.
The glasses you wear for refractory errors like myopia, hyperopia and presbyopia should not be out of date.
Seven insertions were located in the retrotransposon array, indicating that the terminal array is not refractory to P-element integrations.
The blades provide fast cutting of materials that are extremely hard, dense, and relatively nonabrasive, including very hard structural brick, some refractory brick, and very hard natural stone materials.
According to Woese and colleagues, the Darwinian threshold is the point in evolutionary history when the three domains, Bacteria, Archaea, and Eukarya, "crystallize" (Woese's term, 1998) their cellular architectures, which then become refractory to HGT. A Disclaimer for Behe?
It seems that the capability for carefully manipulating and combining agents for use in both inotropic and vasodilator actions has improved our ability to manage previously refractory patients.
In general, the corrosion rate of the alumina refractory and the chrome refractory in the iron phosphate melts was not higher than their corrosion rate in the DWPF melt.
A calculation model of the coefficient of heat transfer between gas and stave body and inlaid refractory is built based on the substitution method of boundary condition.
Gastroesophageal reflux can lead to extraesophageal complications, including laryngitis, chronic cough, refractory asthma and dental erosions.
Centromeric DNA, being highly repetitive, has been refractory to molecular analysis.
The other refractory plants had to have their ganister hauled in by rail.
The medium and small - sized furnace stack gunning with unshaped refractory materials is a new patching technology.
The steel structure of the kiln is protected from the extreme process heat by a refractory lining.
Some compounds of hafnium are also used as refractory substances to line the inside of high-temperature ovens.
It is not known why P-GUS in line 19 was refractory to FLP activity.
The properties of refractory brick and thermal insulating brick for hot stove are described respectively.
It is the excellent raw material for the brick making and the unshaped refractory material making.
The clinical manifestations contain hemorrhage, refractory headache, and epilepsy etc, part of the patients show progressive hemiparalysis due to long-term intracephalic steal blood.
Three days after admission, the patient died of refractory arrhythmia and respiratory failure.
Chut! chut!" says her gossip, Madelaine Manget, and she gives at the same time a pat to a refractory chicken. Lippincott's Magazine, Volume 11, No. 26, May, 1873
In all cases with exogenous DNA inserted into the SalI, SphI, or ClaI site, we find that genomic insertions are largely refractory to mobilization by the active Mos1 transposase.
Mr Mills said KCM had for the past year been carrying out tests to determine the economic value of the dumped refractory ores in an effort to recover and process the hundreds of tonnes of copper.
The eserine has so depressed the action of the esterase at the nerve endings, that the acetylcholine liberated by a single nerve volley lingers there, and reexcites the muscle at each emergence from successive refractory periods, until the concentration falls at last below the stimulation threshold. Sir Henry Dale - Nobel Lecture
Initial therapy of patients with large tumor masses has been complicated by large releases of intracellular potassium with resultant refractory hyperkalemia.
The condensation of iron metal alloy and magnesian silicates (MgSiO 3, enstatite, and Mg 2 SiO 4, forsterite) divides the refractory elements from the moderately volatile elements.
It's time to checkmate this illiterate bottom-feeder and show him that if you've read any of the refractory slop that he has concocted, you'll unmistakably recall his description of his plan to bring about a wonderland of larrikinism. White Mob Disrupts Black Meeting
The utility model relates to a refractory layer anchoring part, in particular to an anchoring part for the sleeve on lime kiln.
Patients with severe, refractory celiac sprue are at an increased risk of developing intestinal T-cell lymphoma.
The shape raised and lowered its refractory outline of a chin. DEAD LINES
It is difficult to economically recover gold from refractory are using conventional processing and metallurgy processes.
Intestinal strictures and bowel obstruction may develop in patients with refractory sprue or celiac disease that has been untreated over a long period.
It is unusual to find a clay being both highly plastic and refractory, and so usually the bond clay is made from a mixture of a stoneware clay or a vitrifiable plastic clay and a refractory clay such as kaolin. 1. Refractories
Refractory bricks for steel production include Basic refractory bricks and High-Alumina refractory bricks.
Any hard, woody materials -- Howard called them "refractory" -- must be thoroughly broken up before composting, otherwise the fermentation would not be vigorous, rapid, and uniform throughout the process. Organic Gardener's Composting
Levinas for example, still go on imperturbably talking about the way "the feminine is the Other refractory to society" (Levinas, Totality and Infinity 265), and, implicitly, about Jehovah as an old man with a long gray beard. Crossroads of Philosophy and Cultural Studies: Body, Context, Performativity, Community
In refractory HF with anasarca, hyperchloremic acidosis was induced to potentiate the effect of intravenous mercurials.
Whatever court he went to (and he was often obliged to go himself to some resty and refractory ones), he as constantly prevailed, and brought them into his measures. Letters to his son on The Art of Becoming a Man of the World and a Gentleman
The steel passing from the tundishes to the moulds is again shrouded with refractory tubes to prevent reoxidation.
They construct it in the sense of developing a conception of the real as being the refractory limit of their own actions.
Even when obtained in solution this potent enzyme destroys acetylcholine with a quite remarkable rapidity; and if we could suppose it to be concentrated on surfaces at preganglionic or motor nerve endings, in immediate relation to the site of liberation and action of acetylcholine, it might furnish an adequate mechanism for the complete destruction of this substance, even during the very brief interval of the refractory period. Sir Henry Dale - Nobel Lecture
Ferrovanadium is a kind of important transitional metal alloy for the tool steel, refractory steel.
However, the BAC-based approach is more efficient for resolving sequencing anomalies and for determining the sequence of regions that are refractory to DNA sequencing, such as regions high in G + C content.
The shape raised and lowered its refractory outline of a chin. DEAD LINES
The burning microporous alumina-carbon brick has good service performance and is a new quality refractory for the area from hearth to middle part of stack.
Dysfunctional uterine bleeding in adolescence is a desease that leads to endocrine dyscrasia of adolescent female. It is refractory and always occurs with metrorrhagia and metrostaxis in turn.
A direct positive inotropic effect and an increase in the refractory period also have been postulated as possible antiarrhythmia mechanisms of spironolactone.
the refractory period of a muscle fiber
Threats of the same treatment prevented refractory congregations from using disused churches they had hired for private worship.
Suboptimal smears had higher RBC count and hemoglobin level and lower platelet count in patients with myelodysplastic syndrome: refractory anemia.
However, with the realisation that the response to levodopa in Parkinson's disease tends to wear off and in itself can produce dyskinesias, pallidotomy gained renewed acceptance as a treatment if the disease proved refractory.
Now, thallium is a much more fusible and vaporizable metal than silver; and its vapour facilitates the passage of the electricity to such a degree, as to render the current almost incompetent to vaporize the more refractory silver. Six Lectures on Light Delivered In The United States In 1872-1873
Synthetic zircon is used to make gemstones that resemble fine diamonds and as a refractory material in foundry molds and furnace linings.
Caspofungin is a Protocol Drug at UIHC and may only be used in patients who are refractory to or intolerant of amphotericin B or amphotericin B lipid complex, or by recommendation of Infectious Diseases Division consult.
If the patient is hypotensive and refractory to IV fluids, pressor agents should be used with extreme caution and the dose carefully titrated to response. Monamine Oxidase Inhibitors
Within a month, De Courcy heard that the castles were pulled down, and, on his calling his refractory vassal to account, received a truly Irish answer: MacMahon said he had not promised to hold stones, but land, and it was contrary to his nature to couch within cold stones, when the warm woods were so nigh. Cameos from English History, from Rollo to Edward II
Lou Dobbs, that paragon of choice xenophobic political battles to pick and win, hopped on this “American Otherness” bandwagon like it was the last copter out of Saigon and is riding it for all it's stupidly worth — which is pretty much just huzzahs and dittoes from the scrape-knuckled fucktards who flock to him post-their mid-afternoon Limbaugh-lovin 'refractory period. Archive 2009-08-01
In the acute isolated bullfrog sciatic nerve, the amplitude, conductivity and refractory period of the action potential were also observed respectively after administration.
The refractory metals include niobium (also known as columbium), tantalum, molybdenum, tungsten, and rhenium.
But the women enrolled in these initial trials were patients with late-stage, metastatic cancers, often heavily pretreated with standard chemotherapies and refractory to all drugs—women carrying the worst and most aggressive variants of breast cancer. The Emperor of All Maladies
The drug is only approved in the US for the treatment of patients with refractory schizophrenia.
They construct it in the sense of developing a conception of the real as being the refractory limit of their own actions.
In addition, our ALN-PCS program represents an opportunity in severe hypercholesterolemia for a novel therapeutic strategy that phenocopies human genetics, and our new program targeting hepcidin creates an opportunity for RNAi therapeutics in the treatment of refractory anemias. Alnylam Launches “Alnylam 5x15” Product Strategy and Provides Guidance and Goals for 2011 - Yahoo! Finance
Furthermore, Rush and colleagues, including Sackeim, are studying the use of vagus nerve stimulation, a promising and moderately invasive treatment for refractory unipolar and bipolar depressions.
Because bioreductive drugs are activated to form highly effective cytotoxins under hypoxic conditions, they can be used to inactivate hypoxic tumor cells that are refractory to the direct cytotoxicity of hypericin-PDT.
-- Come hither, why, you refractory Baggage you, come or I shall touze you, ingenuously I shall; tom, tom, or I'll whip it. The Works of Aphra Behn Volume IV.
In his reply, Mr Goggins said: ‘Special accommodation may only be used for the temporary confinement of a violent or refractory prisoner, and not as punishment.’
The dust is then sifted, the residue is brayed again; refractory stalks are burned to ashes, and this is mixed with the snuff.
Steel tundishes are lined with dense refractory products backed up by insulation materials.
Last, for severe or treatment refractory depression, electroconvulsive therapy is often curative.
A large number of other properties of the nerve fibres vary with the speed of conduction, for instance, the duration of the impulse, its rate of rise, its size, the duration of the inexcitable or refractory period following each impulse, the threshold of excitation, the sensitivity of the discharge to pressure on the nerve and to asphyxia, in short, an array of properties connected with impulse conduction all of which need not vary in an exactly parallel manner. Physiology or Medicine 1944 - Presentation Speech
Occasionally, when confronted with unusual symptoms or signs that are refractory to standard therapy, referral may be indicated.
Furthermore the labeling of the MBP-SEC preparation was refractory to PNGase F, which hydrolyzes N - but not O-linkages.
Although seizures are easily controlled with anticonvulsants in some patients, others are refractory to drugs.
The intravenous and oral formulations are used for the treatment of aspergillosis in patients who are intolerant of or who are refractory to amphotericin B therapy.
However, these guidelines list amiodarone as being only ‘possibly effective’ for the treatment of refractory pulseless ventricular tachycardia or ventricular fibrillation.
Finally the oxyhydrogen blowpipe, which is indispensable for the treatment of very refractory metals, consumes large quantities of hydrogen and oxygen. Scientific American Supplement No. 819, September 12, 1891
Such refractory materials as silicon dioxide and aluminum oxide are so severely attacked that their use is hazardous.
The seal ring consists of a heat insulation sleeve, a refractory fiber layer and a heat-resistant rubber layer, and is made into a sealed circular shape.
In fact there are now some premanufactured refractory firebox retrofits that work well with a 15 to 1 ratio and deliver twice the heat of conventional fireboxes.
By industrial standards a clay is called refractory when it does not soften below 1580 °C. 1. Refractories
With this the refractory gouvernante began in great hurry to adjust her tartan mantle for going abroad, by pulling it so forwards as to conceal the white linen cap, the edges of which bordered her shrivelled but still fresh and healthful countenance. The Fair Maid of Perth
the obedient colonies...are heavily taxed; the refractory remain unburdened
Chemical beneficiation is an effective method for treating refractory phosphate ores.
Although two additional histidine residues are potentially accessible, we focused on the two histidines unique to cx 50 because cx 46 hemichannels were refractory to modification by DEPC.
Within two minutes of cardiac arrest, approximately two thirds of patients develop ventricular fibrillation, but the rhythm becomes increasingly refractory to defibrillation over time.
The problem was rendered still more refractory by the fact that they usually had little idea of the true architecture of the molecule they wanted to make.
When stimulated after the refractory phase (2 s after the spontaneous reversal or later), the cells responded within ~ 2 s to the stimulus.
Thus far, these patients have proved relatively refractory to potential therapies interfering with individual molecules.
The propagative stages of the nematode occur exclusively in adult male crickets; thus adult females crickets are refractory to infection.
The bio-oxidation pretreatment technology provides a sustainable development way for refractory gold concentrate.
Christensen JD: Refractory condylomata acuminata: a controlled clinical trial of carbon dioxide laser versus conventional surgical treatment. We Blog A Lot
All participants had refractory schizophrenia and had been hospitalized for 30 days to 364 days in the previous year.
Laparoscopic uterine nerve ablation and presacral neurectomy also have been used in refractory cases.
Patients with severe, refractory celiac sprue are at an increased risk of developing intestinal T-cell lymphoma.
In scorification the proportion of lead required for scorifying 1 gram of ore is in average cases from 10 to 15 grams, sinking in the case of galena to 2 grams, and rising with earthy and refractory substances to from 30 to 40 grams. A Text-book of Assaying: For the Use of Those Connected with Mines.
Methylergonovine maleate should be restricted to use in refractory cases and should never be used for more than six months continuously.
Equally important is the mineralogical composition of the raw material in primary gold deposits, in which the gold can occur as free gold or bound to pyrite or arsenopyrite as "refractory ore". Chapter 6
Natural graphite is used mostly in what are called refractory applications. Graphite
However, Model 4 cannot reproduce the cellular response to sensory stimuli during the refractory phase of the flagellar motor, because this functional phase was deliberately neglected for a first estimate.
For the purpose of this book the term refractory will cover clays and materials that are suitable to be used in a potter's kiln fired up to 1. Refractories
Lou Dobbs, that paragon of choice xenophobic political battles to pick and win, hopped on this “American Otherness” bandwagon like it was the last copter out of Saigon and is riding it for all it's stupidly worth — which is pretty much just huzzahs and dittoes from the scrape-knuckled fucktards who flock to him post-their mid-afternoon Limbaugh-lovin 'refractory period. “Res-pect Mah Authori-taaaaaayyyyh!”
He also studied the chemical processes involved in making glass, pottery and refractory bricks.
Adjunctive corticosteroids may be beneficial in patients with tuberculous meningitis, tuberculous pericarditis, or miliary tuberculosis with refractory hypoxemia.
AMEP ™, anti-invasive biotherapy, is dedicated to metastatic and invasive melanoma, an advanced skin cancer refractory to most treatments. Health News from Medical News Today
Objective to approach method to treat the refractory aseptic impetiginous dermatosis.
The reason is that the traits of interest, hybrid sterility and inviability, are by their very nature barriers to crossing and thus are refractory to standard genetic approaches.
The clinical manifestations contain hemorrhage, refractory headache, and epilepsy etc, part of the patients show progressive hemiparalysis due to long-term intracephalic steal blood.
Carbonized palm and carbonized hair are made by means of calcination in a sealed refractory vessel.
One of the patterns is heated and clamped on top of a dump box or hopper, which contains the resin-refractory mixture.
Also under investigation as possible container materials are certain types of refractory ceramics.
Since emerging evidence suggests that biomarkers of bone turnover carry notable potential to become useful tools for monitoring patients with metastatic bone disease, we measured a panel of bone formation and bone resorption markers in a relatively homogenous group of patients with hormone-refractory prostatic carcinoma (HRPC) and bone only metastases, immediately before 186Rhenium-l, l-hydroxyethylidene diphosphonate (186Re-HEDP) therapy and strictly after Health News from Medical News Today
Graphite is also used as a refractory in high-temperature furnaces, to make black paint, in explosives and matches, and in certain kinds of cathode ray tubes.
The potters of the Far East were the first to use refractory clays for their kilns. 1. Refractories
In unstimulated cells, the refractory period would take ~ 1-2 s and is prolonged by a repellent stimulus.
Ameni enquired of them as to the preparations for the festival of the morrow, and then desired the chief haruspex to call the refractory pupils together in the school-court. Uarda : a Romance of Ancient Egypt — Volume 05
Kippenberger, even at his most refractory, is an artist of energy, sharp insight, great skill and considerable integrity.
The most refractory substances yielded to the action of the deflagrator, melting like wax before a common fire. Continental Monthly , Vol. 6, No. 1, July, 1864 Devoted to Literature and National Policy.
RA with ringed sideroblasts, 4 RA with excess blasts-1, 24 refractory cytopenia with multilineage dysplasia, 14 refractory cytopenia with multilineage dysplasia with ringed sideroblasts, 4 MDS-unclassified, 2 MDS/Myeloproliferative disorder-U, 4 MDS-del 5q, and 1 Telik Announces Final Positive Phase 2 Results of a Multicenter Study of Oral Ezatiostat Hydrochloride (TELINTRA®, TLK199) in Patients with Myelodysplastic Syndrome - Yahoo! Finance
This glost kiln produces combination of flatware and hollow-ware fired on refractory batts.
The sulphur converted into a state of vapor passes through the conduit, R, into the coke or charcoal retort, G ', which is divided into two parts by the partition, _g g'_, of refractory clay, and heated by the fireplace, L'. Scientific American Supplement, No. 299, September 24, 1881
They were then analyzed for the development of side effects, the indication to use 6-mercaptopurine and azathioprine and the ability to discontinue corticosteroid use in those patients taking 5-acetylsalicylic acid products who were corticosteroid-dependent or whose disease was refractory to treatment. IBD clinical studies: drug comparisons
In the acute isolated bullfrog sciatic nerve, the amplitude, conductivity and refractory period of the action potential were also observed respectively after administration.
It is mostly used as binder and curing agentproduction of hi - temp refractory materials for kiln.
Thus, rather than being refractory to conversion, large heterologies converted as often, or more often, than equidistant small heterologies.
He was a self-indulgence of Bridget's, part of her deliberate, refractory quirkiness for which she, Frances, was now carrying the can. INSTANCES OF THE NUMBER 3
a refractory child
For refractory purposes, high-alumina materials, fire clays, and a product called synthetic mullite (produced in the United States and elsewhere), can be used in place of kyanite and its related minerals. Kyanite
He was a self-indulgence of Bridget's, part of her deliberate, refractory quirkiness for which she, Frances, was now carrying the can. INSTANCES OF THE NUMBER 3
However, this first requires expression of Nef in a resting T cell that is refractory to infection.
High levels of refractory elements such as rhenium can make the alloys prone to the formation of what are known as deleterious topologically close packed The Engineer - News
He was a self-indulgence of Bridget's, part of her deliberate, refractory quirkiness for which she, Frances, was now carrying the can. INSTANCES OF THE NUMBER 3
The tale of Gormenghast requires a large number of refractory animals, few of them capable of taking direction.
The bio-oxidation pretreatment technology provides a sustainable development way for refractory gold concentrate.
At the time-point of stimulation, the cells had recovered from the refractory phase and were fully responsive, whereas nearly none of the cells had reversed spontaneously.
a refractory case of acne
If the patient is hypotensive and refractory to IV fluids, pressor agents should be used with extreme caution and the dose carefully titrated to response. Monamine Oxidase Inhibitors
Then he cautioned them against disobedience and quoth he, "Be ye not deluded by becoming my companions nor say to yourselves, We be the assessors of the King; for that the byword declareth: Whenas the King sitteth beware of his severity, and be not refractory whenever he shall say to thee 'Do.' Arabian nights. English
Severe hepatotoxic events are also noted for an ongoing phase 1/2 combination study in pediatric patients with relapsed or refractory acute leukemia.
His hands were bound behind him, and over his neck was the heavy wooden collar or furca which was placed upon refractory slaves. The Last of the Legions and Other Tales of Long Ago

How To Use Refractory In A Sentence

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