[
UK
/ɹɪfɹˈæktəɹˌi/
]
[ US /ɹəˈfɹæktɝi/ ]
[ US /ɹəˈfɹæktɝi/ ]
ADJECTIVE
-
temporarily unresponsive or not fully responsive to a process or stimulus
the refractory period of a muscle fiber -
stubbornly resistant to authority or control
a fractious animal that would not submit to the harness
a refractory child -
not responding to treatment
a refractory case of acne
a stubborn infection
stubborn rust stains
NOUN
- lining consisting of material with a high melting point; used to line the inside walls of a furnace
How To Use refractory In A Sentence
- Very high dosage fluphenazine for nonchronic treatment-refractory patients. The Neuropsychiatric Guide to Modern Everyday Psychiatry
- That enviably resilient Bayesian model has been cracked, in the eyes of many philosophers, by such refractory phenomena as akrasia or ‘weakness of will.’
- In WS, the three PAI loci are highly refractory to cleavage by either HpaII or MspI, diagnostic of dense CG and CCG methylation of the recognition site.
- They are generally so refractory, self-conceited, obstinate, so firmly addicted to that religion in which they have been bred and brought up, that no persuasion, no terror, no persecution, can divert them. Anatomy of Melancholy
- In refractory cases, monounsaturated fats may replace carbohydrates, but weight and lipid profile should be closely monitored.
- This, in turn, renders cells refractory to subsequent infection by the same or other viruses that use the CD4 receptor for entry; thus creating a state of super-infection immunity.
- Does the downregulation of the FGF23 signaling pathway in hyperplastic parathyroid glands contribute to refractory secondary hyperparathyroidism in CKD patients Naturejobs - All Jobs
- * The effect of this little bit of science may be thus stated -- Men for two years had been punished as refractory for not making all day two thousand revolutions per hour of a 15 lb. crank, when all the while it was a _45 lb. crank_ they had been vainly struggling against all day. It Is Never Too Late to Mend
- ROME -- Long-term gout patients should not be considered "refractory" -- and clinicians should not treat them as such -- until uric crystals are dissolved to the point that flares of pain are prevented, a researcher said here. Medicaid and Medicare
- Fumed silica is used as a filler in the cement and refractory materials industries, as well as in heat insulation and filling material for synthetic rubbers, polymers and grouts. Silicon