How To Use Proto-oncogene In A Sentence
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Activating even two potent proto-oncogenes had not recapitulated the full syndrome of cancer in every cell of the mouse.
The Emperor of All Maladies
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It was shown previously that somatic hypermutability of proto-oncogenes can induce development of lymphomas.
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The FeLV-induced tumors are thought to be caused, at least in part, by somatically acquired insertional mutagenesis in which the integrated provirus may activate a proto-oncogene or disrupt a tumor suppressor gene.
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The normal expression of proto-oncogenes plays an important role in the regulation of spermatogonial mitosis , spermatocyte meiosis as well as spermiogenesis and sperm maturation.
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To test the roles of other oncogenes and environmental stimuli, Leder created a second OncoMouse, in which two activated proto-oncogenes, ras and myc, were engineered into the chromosome and expressed in breast cells.
The Emperor of All Maladies
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Cyclin D1 is a key cell cycle regulator and a candidate proto-oncogene, whose deregulation has been implicated in pathogenesis of several types of cancers, including NPC.
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Objective To explore the correlation between chromosome fragile site in peripheral blood lymphocytes and proto-oncogene expression rate in patients with hepatocellular carcinoma.
