How To Use Point mutation In A Sentence
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These mutagens cause point mutations, because they change the genetic code at one point, so changing a protein's amino acid sequence.
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The different distributions of insertions/deletions and SNPs are clearly related to the two different responsible mechanisms, namely recombination and point mutations.
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Researchers at Jefferson Medical College have used a gene repair technique to genetically change white albino mice hairs to black by correcting a point mutation in the tyrosinase gene.
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The third act of the GFP story began in 1994, when Roger Tsien explained how the chromophore of GFP can form spontaneously in the presence of oxygen and engineered a GFP variant with blue fluorescence, demonstrating that point mutations in the primary structure of GFP can modulate its fluorescence emission spectrum.
The Nobel Prize in Chemistry 2008 - Presentation Speech
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Thus, two of the polymerase mutants are modest spontaneous mutators for some point mutations in yeast strains that are proficient in DNA mismatch repair.
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This indicated that these mutants had point mutations and not exon deletion or insertion.
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What about lateral gene transfer then? does that break the magic line of how much genetic difference constitutes a ‘new’ organism? diploidy? single point mutation? it’s all arbitrary. we can put labels on it for convenience’s sake; but really - we are all really, really, really old.
The Earth’s Elder
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Point mutations were created by oligonucleotide-mediated site-directed mutagenesis and confirmed by DNA sequencing.
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Cremona ML, Amaya MF, Buschiazzo A, Giambiagi S, et al. (2001) Probing molecular function of trypanosomal sialidases: single point mutations can change substrate specificity and increase hydrolytic activity.
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Both large-scale losses via deletion and gene inactivations by revertible point mutations have been observed in modern microbes.
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Objective : To construct enhanced cyan fluorescence protein ( ECFP ) lentiviral vector using the gene multipoint mutation.
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I believe this type of contingency therefore, to be a necessary condition for any change in phenotype requiring more than rudimentary changes genetically, (more than single point mutations certainly), IF, (and that's a big "IF"), those changes occur via the Darwinian mechanism.
Assessing Fault
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Daniel Smith: I believe this type of contingency therefore, to be a necessary condition for any change in phenotype requiring more than rudimentary changes genetically, (more than single point mutations certainly), IF, (and that's a big "IF"), those changes occur via the Darwinian mechanism.
Assessing Fault
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The changes in asexual reproduction are more likely to be a “single point mutation” and get copied in every successive generation.
Think Progress » Poll: Large Number Of Texans Doubt The Theory Of Evolution, Believe In Human-Dinosaur Coexistence
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Fortunately, the excitation maximum of green fluorescent protein is readily shifted to 488 nanometers (in the cyan region) by introducing a single point mutation altering the serine at position 65 into a threonine residue (S65T).
Archive 2005-10-01
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In February 2004, a mitochondrial DNA ( "mtDNA") point mutation analysis revealed a single nucleotide change in the 16S ribosomal RNA gene (T2387C).
David Kirby: The Vaccine-Autism Court Document Every American Should Read
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If we propose that these regulate cistronic activity by their binding of proteins *like* transcription factors and cis/trans factors, *and* their binding of RNA sequences let us regard these too as transcription factors potentially with their own point mutations.
It's more than genes, it's networks and systems - The Panda's Thumb
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The use of immunohistochemical staining as a marker of point mutation has been critically reviewed by Wyndord-Thomas.
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This cell line detects a wide variety of mutagenic lesions, including point mutations, deletions and various types of chromosomal aberrations.
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Probably as Arthur Hunt says, by mistaking complex multigenic changes for single point mutations.
Reality 1, Behe 0 - The Panda's Thumb
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We can only estimate the relative expansion slippage rates and contraction slippage rates compared to the point mutation rate.
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In BCR - fusion gene negative myeloproliferative diseases, the discovery of JAK 2 V 617 F point mutation is an important landmark.
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Unlike most chemical mutagens, which tend to cause point mutations, rays tend to produce larger aberrations such as chromosome deficiencies or rearrangements.
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A small region of monomer B catalytic domain (dark grey) and monomer C oligomerisation domain (light grey) have been included to illustrate the proximity of point mutations with regard to dimer and tetramer interfaces.
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The increase in mutant frequency was attributed to an increase in point mutations.
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Of course, through gene doubling, it IS possible to duplicate a gene, and then have the duplicate altered by point mutation to produce a different protein, such as, say, a hemotoxin component.
"Retraining the Scientific Imagination..." - The Panda's Thumb
