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point mutation

NOUN
  1. (genetics) a mutation due to an intramolecular reorganization of a gene

How To Use point mutation In A Sentence

  • These mutagens cause point mutations, because they change the genetic code at one point, so changing a protein's amino acid sequence.
  • The different distributions of insertions/deletions and SNPs are clearly related to the two different responsible mechanisms, namely recombination and point mutations. PLoS ONE Alerts: New Articles
  • Researchers at Jefferson Medical College have used a gene repair technique to genetically change white albino mice hairs to black by correcting a point mutation in the tyrosinase gene.
  • The third act of the GFP story began in 1994, when Roger Tsien explained how the chromophore of GFP can form spontaneously in the presence of oxygen and engineered a GFP variant with blue fluorescence, demonstrating that point mutations in the primary structure of GFP can modulate its fluorescence emission spectrum. The Nobel Prize in Chemistry 2008 - Presentation Speech
  • Thus, two of the polymerase mutants are modest spontaneous mutators for some point mutations in yeast strains that are proficient in DNA mismatch repair.
  • This indicated that these mutants had point mutations and not exon deletion or insertion.
  • What about lateral gene transfer then? does that break the magic line of how much genetic difference constitutes a ‘new’ organism? diploidy? single point mutation? it’s all arbitrary. we can put labels on it for convenience’s sake; but really - we are all really, really, really old. The Earth’s Elder
  • Point mutations were created by oligonucleotide-mediated site-directed mutagenesis and confirmed by DNA sequencing.
  • Cremona ML, Amaya MF, Buschiazzo A, Giambiagi S, et al. (2001) Probing molecular function of trypanosomal sialidases: single point mutations can change substrate specificity and increase hydrolytic activity. PLoS ONE Alerts: New Articles
  • Both large-scale losses via deletion and gene inactivations by revertible point mutations have been observed in modern microbes.
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