How To Use Pharmacokinetics In A Sentence
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In addition, 21 of the 102 SNPs that predicted MRD also significantly associated with the pharmacokinetics of two antileukemic drugs, etoposide and methotrexate, which are representative of the array of antileukemic medications used to treat lymphoblastic leukemia.
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For those who teach basic principles of medicinal chemistry, pharmacology or pharmacokinetics this book provides a valuable resource for examples and mechanisms of drug-drug interactions.
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Although age-related analgesic effects are extremely variable among elderly patients, changes in pharmacokinetics and pharmacodynamics could account for various adverse effects in this population.
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Its unique pharmacokinetics and pharmacodynamics make methadone a valuable option, but physicians should be aware of possible side effects.
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As oral cephalosporins have poor pharmacokinetics it would seem that amoxicillin or amoxicillin-clavulanate should usually be the first choice for therapy.
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OBJECTIVE To establish a LC-MS/MS method for the simultaneous determination of guaifenesin, bromhexine, ambroxol in human plasma and to study their pharmacokinetics in healthy volunteers.
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A one-year open label, non-comparative extension to a randomized, multicenter, phase II study to evaluate the safety, tolerability, pharmacokinetics and the effects on liver iron concentration of repeated doses of 5-30 mg/kg/day of ICL670 (deferasirox) relative to deferoxamine in sickle cell disease patients with transfusional hemosiderosis
Sickle cell disease research at The Children's Hospital
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What drugs alter prothrombin time by interacting with warfarin levels ( pharmacokinetics )?
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Does the patient have any metabolic impairments that would alter the pharmacokinetics or the pharmacodynamics of the drug (ie, impaired renal or liver function)?
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Objective:To observe the changes of fentanyl pharmacokinetics in rats during anhepatic phase by treatment of large dose of dexamethasone and to investigate the extrahepatic metabolism of fentanyl.
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Genetics influence drug efficacy and pharmacokinetics in individuals through variability uptake and metabolism of medications.
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But what you can compare is total estrogen exposure, something pharmacokinetics experts call "the area under the curve" or AUC.
Thoughts on the Contraceptive Patch and Blood Clot Risks
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Possible influences of ginseng on the pharmacokinetics and pharmacodynamics of warfarin in rats.
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• Pharm D, M.D., and / or Ph. D. in a discipline closely related to pharmacokinetics, immunopharmacology, or pharmacogenetics.
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( "docent") (Tenure Track system) in the Department of Bioanalysis, charged with academic teaching (in Dutch), scientific research and carrying out scientific duties in the fields of pharmacokinetics and pharmaceutical care.
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In children, GSTM1 polymorphism seems to modify BU pharmacokinetics after intravenous drug administration. busulfan, hematopoietic stem cell transplantation, glutathione
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Methadone's unique pharmacokinetics and pharmacodynamics make it a valuable option in the management of cancer pain and other chronic pain, including neuropathic pain states.
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It is not clear, however, how well these results may be extrapolated to pediatric patients, because of the marked differences in pharmacokinetics of nitrofurantoin in adults and children.
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These proposed services adapt to the validation and development of anti - cancer drug candidates and are fully validated such as sub-cutaneous and orthotopic tumors models in animals; in vitro and in vivo angiogenesis models; an original "Nodule" system, tumor invasion tests, in vivo imaging, bio-distribution, pharmacokinetics, toxicity, histological analysis, biomarker studies, ...
THE MEDICAL NEWS
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The pharmacokinetics and pharmacodynamics of drugs can change unpredictably in patients at the end of life.
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The first section is dedicated to the fundamental principles of toxicology, including chapters on postmortem forensic toxicology, performance toxicology, forensic drug testing, and pharmacokinetics and pharmacodynamics.
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Because of the large inter-individual variability in indomethacin pharmacokinetic in neonates, it is to be established to what degree the patient characteristics influence the pharmacokinetics of drugs.
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Other factors, including drug potency, receptor affinity, and pharmacokinetics also influence these outcomes.
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The text has carried on detailed analysis to Pharmacokinetics and neuropharmacology of Ganfukang dropping pill .
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Future work must delineate the social and biological factors, including any differences in pharmacokinetics associated with chemotherapeutic agents, that account for disparities in outcome.
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