pharmacokinetics

NOUN
  1. the study of the action of drugs in the body: method and rate of excretion; duration of effect; etc.
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How To Use pharmacokinetics In A Sentence

  • In addition, 21 of the 102 SNPs that predicted MRD also significantly associated with the pharmacokinetics of two antileukemic drugs, etoposide and methotrexate, which are representative of the array of antileukemic medications used to treat lymphoblastic leukemia. Undefined
  • For those who teach basic principles of medicinal chemistry, pharmacology or pharmacokinetics this book provides a valuable resource for examples and mechanisms of drug-drug interactions.
  • Although age-related analgesic effects are extremely variable among elderly patients, changes in pharmacokinetics and pharmacodynamics could account for various adverse effects in this population.
  • Its unique pharmacokinetics and pharmacodynamics make methadone a valuable option, but physicians should be aware of possible side effects.
  • As oral cephalosporins have poor pharmacokinetics it would seem that amoxicillin or amoxicillin-clavulanate should usually be the first choice for therapy.
  • OBJECTIVE To establish a LC-MS/MS method for the simultaneous determination of guaifenesin, bromhexine, ambroxol in human plasma and to study their pharmacokinetics in healthy volunteers.
  • A one-year open label, non-comparative extension to a randomized, multicenter, phase II study to evaluate the safety, tolerability, pharmacokinetics and the effects on liver iron concentration of repeated doses of 5-30 mg/kg/day of ICL670 (deferasirox) relative to deferoxamine in sickle cell disease patients with transfusional hemosiderosis Sickle cell disease research at The Children's Hospital
  • What drugs alter prothrombin time by interacting with warfarin levels ( pharmacokinetics )?
  • Does the patient have any metabolic impairments that would alter the pharmacokinetics or the pharmacodynamics of the drug (ie, impaired renal or liver function)?
  • Objective:To observe the changes of fentanyl pharmacokinetics in rats during anhepatic phase by treatment of large dose of dexamethasone and to investigate the extrahepatic metabolism of fentanyl.
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