How To Use Penicillinase In A Sentence
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C. Resistance to penicillin is mediated both by plasmid-encoded penicillinase and by changes in chromosome-encoded proteins that control the permeability of the drug.
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After all, the resistant strain has the genetic information necessary to produce penicillinase, which is a complex chemical.
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The object of interest was the so-called large domain of the TEM-1 penicillinase, an enzyme that breaks down antibiotics related to penicillin.
Axe (2004) and the evolution of enzyme function - The Panda's Thumb
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These chemically modified penicillins have a side chain that inhibits the action of penicillinase.
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Recall that Axe did not work with the native TEM-1 penicillinase, but rather with a variant that had a lower activity.
Axe (2004) and the evolution of enzyme function - The Panda's Thumb
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Staphylococcus aureus (MRSA), resulting in the concept that MRSA has emerged on a few occasions after penicillinase-stable β-lactam antibiotics were introduced to clinical practice, followed by intercontinental spread of individual clones.
Proceedings of the National Academy of Sciences current issue
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Consider a penicillinase-resistant penicillin (such as methicillin or nafcillin) or vancomycin plus an aminoglycoside or aztreonam.
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Oral antibiotics are usually used in the treatment and include first-generation cephalosporins, penicillinase-resistant penicillins, macrolides, and fluoroquinolones.
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Penicillin was first used in the early 1940s and by 1950, most Staphylococcus aureus organisms were resistant to the drug by virtue of elaboration of a penicillinase enzyme.
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A control gene regulates the production of an enzyme that destroys the antibiotic, e.g. penicillinase which destroys penicillin.
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- Antibacterial (antibiotic) of the penicillin group, acting specifically against penicillinase producing staphylococci
Chapter 4
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Before I discovered I wasn't cut out to be a bench biochemist, my undergraduate research was on "Competitive inhibition of penicillinase by notalysin, a
Citizendium, the Citizens' Compendium - Recent changes [en]
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Axe’s numbers tell us about the apparent isolation of the low-activity variant, but reveal little nor can it be expected to about the “isolation” or evolution of TEM-1 penicillinase.
Axe (2004) and the evolution of enzyme function - The Panda's Thumb
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For example, the resistance to penicillin initially was due to production of an enzyme penicillinase by bacteria, antibiotics like cloxallin were developed which was resistant to penicillinase enzyme.
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If antibiotics are required, one that is active against gram-positive organisms such as penicillinase-resistant penicillins, cephalosporins, macrolides, or fluoroquinolones should be chosen.
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Therefore it is necessary to treat breast infections with a penicillinase-resistant antibiotic such as either flucloxacillin or erythromycin.
Chapter 39
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An example would be the bacteria that secrete penicillinase, which is an enzyme that destroys penicillin.
Cities In Flight
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Since 1948 his research topics have included carbohydrate-amino acid relationship in nervous tissue, a study of the mode of action of insulin, fermentation technology, 6-aminopenicillanic acid and penicillinase-stable penicillins, lysergic acid production in submerged culture, and the isolation of new fungal metabolites.
Ernst B. Chain - Biography
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In an almost-standard sandwich-type configuration, penicillinase enzyme was attached to the target cells using anti-penicillinase and bridging antibodies.
The Scientist