How To Use Homozygote In A Sentence
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If the mutation is question is severely deleterious, for example if homozygote embryos invariably die during development to take an extreme example, it can never be fixed.
The Rise of Human Chromosome 2: Beyond the Deme - The Panda's Thumb
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A final, important point is that even with just those two simple mutations the process is convoluted almost to the point of incoherence.17 Even with just the sickle and C genes—with heterozygote versus homozygote advantage and with varying detrimental effects—the interplay of the mutant and normal genes is chaotic and tangled.
The Edge of Evolution
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A2A2 homozygote, the lower the equilibrium frequency of A2, for a given value of
Population Genetics
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B framework is quite restricted when it comes to explaining why recessive mutants are so common, the appearance of dominant mutations, the existence of functional recessive homozygotes, the phenomenon of overdominance, and how genetic dominance may arise from intralocus interaction
PLoS ONE Alerts: New Articles
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Results For the same SNP locus, the homozygote showed a single product peak, and the heterozygote showed two product peaks with different length.
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This phenotype is intermediate between the two homozygotes and therefore no complementation is observed.
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Expression in heterozygotes and homozygotes is apparently identical.
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Thus, CFTR -/- homozygotes displayed defective chloride transport in epithelia of airways and intestines, failure to thrive, meconium ileus, and pathological alterations of gastrointestinal glands.
The 2007 Nobel Prize in Physiology or Medicine - Advanced Information
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However, after several backcrosses, its heterozygotes could be distinguished from the dominant homozygotes.
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This is because inbred individuals are more likely to express deleterious alleles as homozygotes than are outbreds.
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For example, in inbred populations there may be very few heterozygotes but several different homozygotes.
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Within a sexual population, however, the segregation of alleles would break down the genetic association, and the less fit homozygotes would be formed by syngamy each generation.
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I added it to the list on our Instructors' Blog, stated as follows:Students should be able to define dominance as a particular relationship between the effects of two alleles; dominance is said to exist when the phenotype of the heterozygote is the same as that of a homozygote for one of the alleles the 'dominant' one.
How to teach about dominance
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I would posit that the low-lifespan-after-senescence-onset would likely have a similar effect -- heterozygotic organisms (and maybe the homozygotes too) may have an advantage in terms of metabolism or ability to reproduce or something.
Boing Boing
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That's about 450 is the US units. 600 has been recorded (rarely) amongst people with the heterozygotic (1 copy) form of the mutation, and nearly double that for homozygotes (2 copies).
Archive 2005-05-01
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For example, in inbred populations there may be very few heterozygotes but several different homozygotes.
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Homozygotes and heterozygotes at individual sites were distinguished by their chromatographic patterns.
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Similarly, inbreeding decreases the effective size of selection but unmasks deleterious alleles in homozygotes.
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So, the idea is that some allele exists which confers an evolutionary benefit when present in the heterozygote stronger sperm, for example, and confers homosexuality in the homozygote.
"The more we play God or try to improve on Mother Nature, the more damage we are doing with all kinds of experiments that... turn into nightmares."
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HOMOZYGOTE (same yolk), an individual which contains only one member of an allelomorphic pair, but contains that in duplicate, having received it from both parents.
Applied Eugenics
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This is where the heterozygote has a higher fitness than either homozygote.
Red Lynx Simulator - The Panda's Thumb
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Instead, they are directly related to the allele frequency of the homozygote tested and the sample size.
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The eye color of homozygotes and heterozygotes was compared in flies of the same age and sex.
