[
US
/ˌhoʊmoʊˈzaɪɡoʊt/
]
NOUN
- (genetics) an organism having two identical alleles of a particular gene and so breeding true for the particular characteristic
How To Use homozygote In A Sentence
- If the mutation is question is severely deleterious, for example if homozygote embryos invariably die during development to take an extreme example, it can never be fixed. The Rise of Human Chromosome 2: Beyond the Deme - The Panda's Thumb
- A final, important point is that even with just those two simple mutations the process is convoluted almost to the point of incoherence.17 Even with just the sickle and C genes—with heterozygote versus homozygote advantage and with varying detrimental effects—the interplay of the mutant and normal genes is chaotic and tangled. The Edge of Evolution
- A2A2 homozygote, the lower the equilibrium frequency of A2, for a given value of Population Genetics
- B framework is quite restricted when it comes to explaining why recessive mutants are so common, the appearance of dominant mutations, the existence of functional recessive homozygotes, the phenomenon of overdominance, and how genetic dominance may arise from intralocus interaction PLoS ONE Alerts: New Articles
- Results For the same SNP locus, the homozygote showed a single product peak, and the heterozygote showed two product peaks with different length.
- This phenotype is intermediate between the two homozygotes and therefore no complementation is observed.
- Expression in heterozygotes and homozygotes is apparently identical.
- Thus, CFTR -/- homozygotes displayed defective chloride transport in epithelia of airways and intestines, failure to thrive, meconium ileus, and pathological alterations of gastrointestinal glands. The 2007 Nobel Prize in Physiology or Medicine - Advanced Information
- However, after several backcrosses, its heterozygotes could be distinguished from the dominant homozygotes.
- This is because inbred individuals are more likely to express deleterious alleles as homozygotes than are outbreds.