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alkylating agent

NOUN
  1. an antineoplastic drug used to treat some forms of cancer

How To Use alkylating agent In A Sentence

  • Chemical mutagens are classified as alkylating agents, cross-linking agents, and polycyclic aromatic hydrocarbons (PAHs).
  • The mms4 mutant has previously been found to be sensitive to alkylating agents such as MMS, weakly sensitive to ultraviolet light, and resistant to X rays.
  • Parp is activated by DNA strand breaks induced by alkylating agents.
  • The hydrocarbon diperchlorate products have utility as detonatable sensitizers for explosives and alkylating agents.
  • PARP is a nuclear enzyme activated by DNA strand breaks induced by alkylating agents or X-rays.
  • Drugs such as alkylating agents, antimetabolites, anticonvulsants, chlorothiazide diuretics and estrogens can inhibit platelet production by suppressing megakaryocyte production. (2,3)
  • All four mutant lines displayed an increased sensitivity to the bifunctional alkylating agent mitomycin C.
  • People undergoing cancer treatment such as radiation and chemotherapy and use of radiomimetic alkylating agents develop secondary Myelodysplastic syndrome as an effect of late toxicity caused by the treatment. Undefined
  • Consistent with these functions, mei - 41 mutants are sensitive to hydroxyurea, an inhibitor of DNA replication, and DNA-damaging agents such as X-ray and alkylating agents.
  • We found that it is also hypersensitive to various DNA-damaging agents, including UV irradiation and the DNA alkylating agent MMS.
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