How To Use alkylating agent In A Sentence
- Chemical mutagens are classified as alkylating agents, cross-linking agents, and polycyclic aromatic hydrocarbons (PAHs).
- The mms4 mutant has previously been found to be sensitive to alkylating agents such as MMS, weakly sensitive to ultraviolet light, and resistant to X rays.
- Parp is activated by DNA strand breaks induced by alkylating agents.
- The hydrocarbon diperchlorate products have utility as detonatable sensitizers for explosives and alkylating agents.
- PARP is a nuclear enzyme activated by DNA strand breaks induced by alkylating agents or X-rays.
- Drugs such as alkylating agents, antimetabolites, anticonvulsants, chlorothiazide diuretics and estrogens can inhibit platelet production by suppressing megakaryocyte production. (2,3)
- All four mutant lines displayed an increased sensitivity to the bifunctional alkylating agent mitomycin C.
- People undergoing cancer treatment such as radiation and chemotherapy and use of radiomimetic alkylating agents develop secondary Myelodysplastic syndrome as an effect of late toxicity caused by the treatment. Undefined
- Consistent with these functions, mei - 41 mutants are sensitive to hydroxyurea, an inhibitor of DNA replication, and DNA-damaging agents such as X-ray and alkylating agents.
- We found that it is also hypersensitive to various DNA-damaging agents, including UV irradiation and the DNA alkylating agent MMS.
