1. an antineoplastic drug used to treat acute leukemias
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How To Use thioguanine In A Sentence

  • A competitive pathway also converts 6-MP to its cytotoxic 6-thioguanine nucleotides (6-TGNs) that are associated with bone marrow suppression (leukopenia, neutropenia, thrombocytopenia). Clinical studies: IBD treatment safety
  • Life-threatening ways and assuming have supported observed as linkages of thioguanine-induced granulocytopenia and thrombocytopenia. Wii-volution
  • Thioguanine later found its main utility in the treatment of acute myelocytic leukemia in adults, in combination with cytosine arabinoside. Nobel Lecture The Purine Path To Chemotherapy
  • She was treated with a chemotherapeutic regimen that included daunorubicin, cytosine, and thioguanine.
  • This lead to the loss of antitumor activity, with the exception of the 2-amino-6-mercapto derivative, thioguanine, which we had previously found to have strong antimetabolic activity. Nobel Lecture The Purine Path To Chemotherapy
  • He was diagnosed with acute monoblastic leukemia (AML-MSa) and subsequently underwent induction therapy with daunorubicin, 6-thioguanine, and cytosine arabinoside.
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