How To Use Tamoxifen In A Sentence
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In addition to the initial therapy, most patients received tamoxifen in a dosage of 20 mg daily as adjuvant treatment.
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This patient's doctor may be able to get her free tamoxifen.
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Cataract surgery was required approximately twice as often among women who took tamoxifen.
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Drugs like Tamoxifen and the newer drugs that are often called aromatase inhibitors.
NPR Topics: News
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Hormone therapy (for example, tamoxifen, letrozole, anastrozole and goserelin) improve survival rates and reduce recurrence.
Times, Sunday Times
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These treatments may involve drugs such as tamoxifen, which are meant to prevent the cancer from growing again.
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Tamoxifen had little effect on recurrence or death in women who were classified in these trials as having ER-poor disease[Sentence dictionary], and did not significantly modify the effects of polychemotherapy.
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What are the findings from the third study, which examines switching to an aromatase inhibitor after two to three years of tamoxifen?
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These have shown that tamoxifen alone is inadequate treatment (and so, probably, is treatment with aromatase inhibitors alone) and should be given only to very frail women with a life expectancy of less than a year.
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When the main tamoxifen trials were published in 1983, dissemination into practice took about five years.
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Some studies suggest that tamoxifen interferes with brain metabolism and cognitive function.
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Current treatment commonly centres on tamoxifen, another drug which shrinks tumours.
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The risk did not decrease after discontinuation of tamoxifen and was not modified by other risk factors for endometrial cancer.
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The risk is small compared to the benefits of using tamoxifen to treat breast cancer.
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This crystalline retinopathy is rarely seen with standard doses of tamoxifen, but when present it can cause a substantial progressive drop in visual acuity.
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‘But greater use of tamoxifen has had a huge impact over the past 10 years,’ he added.
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The findings add to an accumulation of evidence suggesting that inhibition of the cytochrome P450 2D6 isozyme (CYP2D6) may adversely affect outcomes in breast cancer patients taking tamoxifen.
MedPageToday.com - medical news plus CME for physicians
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The ATAC study is an international collaboration which compared the safety and efficacy of tamoxifen with anastrozole alone and the combination of both drugs for 5 years.
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Unlike tamoxifen, aromatase inhibitors do not cause menopausal symptoms, but they may increase risk of osteoporosis.
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Resistance to tamoxifen is thought to be an epithelial 'cancer cell' phenomenon, but we show here that it is clearly a 'stromal' phenomenon," Dr. Lisanti said.
Science Blog - Science news straight from the source
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Hormone therapy (for example, tamoxifen, letrozole, anastrozole and goserelin) improve survival rates and reduce recurrence.
Times, Sunday Times
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For example, thyroxine for thyroid cancer, tamoxifen for oestrogen receptor positive breast cancer, and stilboestrol for cancer of the prostate.
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They were receiving endocrine therapy such as anastrozole (Arimidex) or tamoxifen to reduce cancer recurrence risk.
Yahoo! News: Business - Opinion
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Goss and colleagues present data on the use of an aromatase inhibitor, letrozole, for prevention of breast cancer recurrence in women who have completed five years of tamoxifen therapy.
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However, known carcinogens include alcoholic beverages, estrogen treatments for menopause symptoms, birth control pills, certain viruses and parasites, and even some drugs used to treat cancer, such as cyclophosphamide and tamoxifen.
Weighing cancer risks, from cellphones to coffee
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The question of how long patients should continue taking the drug is important because tamoxifen is not problem free.
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As a preventive measure, taking tamoxifen doesn't guarantee that you'll remain cancer-free.
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About half in each of these groups were treated with chemotherapy followed by five years of tamoxifen.
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The authors suggest that tamoxifen may be underused in selected groups of women who could benefit from prophylaxis.
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In these tests, advertised as drug response profiles, the companies check for some DNA segments that encode enzymes involved in metabolizing some drugs like tamoxifen, methotrexate, Plavix (clopidogrel), coumadin and others.
Dr. Elaine Schattner: An Educated Medical Consumer: On Personal DNA Testing
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His work with another called SRC-3 has led to better understanding of cancer and inflammation and led to the understanding of drugs such as tamoxifen in the treatment of breast cancer.
Health News from Medical News Today
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Retinoic acid, tamoxifen, and the two telomerase inhibitors each significantly squelched immortalization.
The Scientist
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Can you use tamoxifen or an aromatase inhibitor to prevent breast cancer in the first place?
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Patients managed as outpatients (such as those treated with tamoxifen only) were likely to be missed.
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Drugs such as venlafaxine (brand name includes Effexor) or citalopram (Celexa) don't appear to interfere with tamoxifen "to anywhere near the same degree.
Canada.com Top Stories
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While looking through her papers, her family discovered she was one of the first to investigate the use of the drug Tamoxifen in cancer care.
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The effect found for tamoxifen also reduced the overall incidence of osteoporotic fractures of the hip, spine and radius by 19%.
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Another approach is to use an anti-estrogen drug like tamoxifen preventively in postmenopausal women whose histories of breast problems indicate that they are at high risk of developing cancer; I am involved in a study that is examining this kind of treatment.
Good News and Bad News About Breast Cancer
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The results come from continued long - term follow - up of tamoxifen study by the Swedish Breast Cancer Group.
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In rat liver, it has been shown that tamoxifen forms covalent DNA adducts, implying a genotoxic mechanism for its carcinogenicity in this tissue.
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As with all medicines, tamoxifen has side effects that may affect some women and not others.
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Hormonal therapy for postmenopausal women using chemicals such as tamoxifen is cytostatic, meaning it stops estrogen from stimulating breast cancer cells.
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We do not know if raloxifene is better than tamoxifen.
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One other variation is to do both chemo and tamoxifen.
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Giordano, Donatella Vizza, Salvatore Panza, Ines Barone, Daniela Bonofiglio, Suzanne A. Fuqua, Stefania Catalano and Sebastiano A.dò carried out the study, "A.tivated farnesoid X receptor inhibits growth of tamoxifen resistant breast cancer cells.
Newswise: Latest News
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As this history is often incomplete, our measured population of all patients on tamoxifen is grossly underestimated.
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However, personal history, such as abnormal biopsy, was highly correlated with the decision to take tamoxifen.
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Much of the success for the development of tamoxifen, goserilin, and anastrozole in the treatment of early or metastatic breast cancer can be attributed to Ian's ceaseless energy and zeal.
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Interestingly, tamoxifen was originally invented in the UK as a post-coital contraceptive.
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It is scientifically sound that soy estrogenic compounds may act like tamoxifen to interfere with the activity of estrogen and reduce the risk of recurrence of breast cancer.
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