How To Use Polymorphism In A Sentence
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A common goal of population genetic investigations is to explain the fate of genetic polymorphism within a species.
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This was an exciting period in the molecular biology of adenovirus with the discoveries (a) that only one specific fragment of the genome, the E1 region, was responsible for oncogenic transformation; (b) that restriction endonuclease length polymorphism could be utilized to generate genetic maps; (c) the mapping of specific genes on the viral genome; and (d) generation of a viral map of sequences expressed as stable RNAs.
Phillip A. Sharp - Autobiography
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This is a textbook example of polymorphism — many types accessed through one uniform interface.
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Renin and atrial natriuretic peptide restriction fragment length polymorphisms: association with ethnicity and blood pressure.
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The high polymorphism of MHC genes in Chinese alligator would be of great benefit to genetic conservation in the captive population of Chinese alligator.
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Restriction Fragment Length Polymorphism(RFLP)is a new genetic marker.
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Future clinical trials may be aimed at specific patient populations determined by genetic polymorphism and other risk factors.
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Objective:To investigate the interaction effect of parathyroid hormone(PTH) gene polymorphism with calcium intake on bone mass accretion in Chinese adolescent girls.
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- meaning "information hiding" in the general sense, and not necessarily a particular programming mechanism such as polymorphism or some such thing.
WindowsClient.net
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It uses a technique called polymorphism, a mechanism that can use compression and encryption to make the code appear different to antivirus software and more difficult to detect.
Infoworld News
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Our aim was to test whether an intrasexual polymorphism, facultative paedomorphosis (a process in which the development of somatic and gonadal tissues differs in alternative morphs), could affect SSD variation patterns in European newts.
BioMed Central - Latest articles
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Microsomal epoxide hydrolase detoxifies reactive oxygen species generated by endotoxin exposure, and polymorphisms of the miH gene are associated with altered enzyme activity.
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Google also found that legitimate antivirus vendors were having more trouble identifying the fake programs due to an increased level of "polymorphism," a technique used to make an application look unique and evade malware scanners.
ARN News
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Hence, the polymorphism hypothesis is attractive because it could help to explain how a segmentally duplicated genome such as that of maize can avoid deleterious ectopic recombination between paralogs.
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Examples of the concept include Integration and polymorphism: degree of autonomy of individual versus integration of specialized individuals, relative degrees of fitness (Boardman and Cheetham, 1973; Schopf, 1973; Bates and Kirk, 1985; Pitelka and Ashmun, 1985; Mackie, 1986).
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METHODS:Polymerase chain reaction restriction fragment length polymorphism(PCR RFLP) was used to analyze NQO1 gene polymorphism in Parkinson disease group and healthy adult control group.
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The study by Seielstad, Minch, and Cavalli-Sforza may be regarded as the pioneer study on the relations between genetic variation of unilinearly transmitted polymorphisms and sociocultural factors.
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Therefore, efforts to discover such phenomena were undertaken mainly for polymorphism data from regions of low recombination.
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However, to retain this hypothesis, we would have to eliminate the alternative explanation that the observed polymorphism is because of secondary admixture of differentiated populations.
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Methods The 104 patients with CVD and 98 healthy individuals were detected the AT1R genotypes polymorphisms by restriction fragment length polymorphism in order to analysis.
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Method Polymerase chain reaction and restriction fragment length polymorphism were used to examine 40 oral malignant tumors for loss of heterozygosity at chromosome 3p.
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Methods We used the polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) to examine 40 oral squamous cell carcinomas for loss of heterozygosity (LOH) at APC.
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He had begun a study of prion autocatalysis in yeast and became interested in the significance of polymorphisms in human genes that encode molecules involved in drug transport and metabolism.
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Phylogenesis of 48 tobacco germplasms from different countries or regions was analyzed with amplified fragment length polymorphism (AFLP).
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To investigate the molecular mechanism of IMF deposition, we explored the expression patterns of lipoprotein lipase (LPL) gene, hormone sensitive lipase (HSL) gene and the polymorphism of LPL gene.
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Recent advances in genome-wide single-nucleotide polymorphism (SNP) analyses have revealed previously unrecognized microdeletions and uniparental disomy (UPD) in a broad spectrum of human cancers.
Naturejobs - All Jobs
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Methods Single round Touchdown PCR (TD PCR) and restriction fragment length polymorphism (RFLP) method were used for genotyping in 110 people from the Han population in Chongqing.
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All selected polymorphisms were verified by re-sequencing DNA taken from the mice used in the backcross.
PLoS ONE Alerts: New Articles
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This may be due to the complete absence of functional Ea and/or non-polymorphism of the Ea gene product.
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Objectives: To study the association between M235T allele polymorphism in exon 2 of angiotensinogen(AGT) gene and essential hypertension(EH).
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Recent epidemical study indicates that the incidence of AD in some populations is substantially influenced by the gene polymorphisms of the inflammation mediators.
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This may be related to the large size of the chromosomal DNA to be deleted, to polymorphism at this locus, or to specific effects of the donor DNA.
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Organisms exhibiting genetic polymorphism often also exhibit true alternative life-history strategies in which behavioral tactics are genetically fixed.
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The presence of high levels of nucleotide diversity, however, is only one characteristic of the signature of a balanced polymorphism.
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By contrast, we found that PINK1 containing the G411S polymorphism, which is conserved in vertebrates, but not invertebrates, could compensate for loss of endogenous PINK1, consistent with the view that PINK1 G411S may be a natural variant and not a disease-causing mutation.
PLoS Biology: New Articles
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Method 32 cases of hydatidiform mole were analyzed by DNA restriction fragment length polymorphism (RFLP, hybridized with the probe 33.15).
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Objectives: To study the association between M235T allele polymorphism in exon 2 of angiotensinogen(AGT) gene and essential hypertension(EH).
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Method Polymerase chain reaction and restriction fragment length polymorphism were used to examine 40 oral malignant tumors for loss of heterozygosity at chromosome 3p.
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Single strand conformation polymorphism (SSCP) essay and sequence analysis of the PCR product were used to ascertain the gene mutation.
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The first direct observation of nucleotide variation on the fourth chromosome was an analysis of polymorphism at the cubitus interruptus gene in D. melanogaster and simulans.
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Since that time there have been numerous studies, particularly on animal cells, investigating mitochondrial polymorphism and behaviour.
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IBS is caused by a polymorphism of the serotonin receptors lining the digestive tract, causing digestive dysfunction based on mood.
The Volokh Conspiracy » Adderall
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Methods Single round Touchdown PCR (TD PCR) and restriction fragment length polymorphism (RFLP) method were used for genotyping in 110 people from the Han population in Chongqing.
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The applications of karyotyping and restriction fragment length polymorphism (RFLP) analyses, specific DNA probes and PCR method to the diagnosis of Candida albicans infections are reviewed.
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(An allele is any of the variants of a gene that takes more than one form; such genes are known as polymorphisms.
The Science of Success
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The aluminium silicate minerals andalusite, kyanite, and sillimanite are good examples of this phenomenon of polymorphism.
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Method 32 cases of hydatidiform mole were analyzed by DNA restriction fragment length polymorphism (RFLP, hybridized with the probe 33.15).
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I would also add that there are living species which I believe Dave knows about more than I that maintain karyotypic polymorphism within their populations.
The Rise of Human Chromosome 2: Beyond the Deme - The Panda's Thumb
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The TPH gene A218C polymorphism and the MAOA gene T1460C polymorphism were determined by the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique.
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Most polymorphism thus appears to predate the split of these closely related genera.
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We investigated the association between 48 coding and three non-coding single nucleotide polymorphisms (SNPs) from 35 inflammatory genes and the development of CAD, using a large discordant sibship collection (2699 individuals in 891 families).
BioMed Central - Latest articles
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Objective To examine the methylenetetrahydrofolate reductase ( MTHFR ) gene polymorphism in women with recurrent pregnancy loss ( RPL ).
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You also need to make sure that you do not sneak a noncompliant object through your interface using polymorphism .
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The remaining ‘incongruous’ crosses disagreeing in gene order with the largest clique were used to infer the existence of inversion polymorphism.
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Conditions for the selective maintenance of stable polymorphisms by antagonistic pleiotropy are quite restrictive.
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They also speculate that the variable effects of beta antagonists may be caused by genetic polymorphisms in the beta-adrenergic receptor.
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Polymorphism is the capability of something to assume different forms.
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In particular, if a sample is taken from such a population, levels of polymorphism within and between demes will be the same.
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A sketch about patterns, interfaces and polymorphism preceded a discussion of the Memento, Command and Objects for State patterns, which were fine and relatively unambiguous.
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Identification of the gene encoding s-ADH and the eventual search for polymorphisms are awaited with interest.
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Terminal restriction fragment length polymorphism is a new microbioecology technique.
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Xylan in nature is a complex of many polysaccharides, and this makes it appears polymorphism and poly-sphere, therefore, it is necessary to classify xylanase of great variety.
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AFLP (amplified fragment length polymorphism) is a new DNA molecular marker technique with high efficiency, promptitude, stability and accuracy.
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Sure OOP introduced constructs such as polymorphism and interfaces etc to wiggle this, but imperfectly.
Tooling Around
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A peak in the graph is expected to be centered around a site containing a balanced polymorphism.
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Late binding in addition to data types provides a needed aspect to allow polymorphism or the choosing of an object's method implementation at run-time.
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A multidisciplinary international team demonstrated through botanical examination, phytochemical investigation, and genetic deoxyribonucleic acid analysis by polymerase chain reaction that this material contained tetrahydrocannabinol, the psychoactive component of cannabis, its oxidative degradation product, cannabinol, other metabolites, and its synthetic enzyme, tetrahydrocannabinolic acid synthase, as well as a novel genetic variant with two single nucleotide polymorphisms.
2,700-year-old marijuana stash found
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All eg95 sequences showed double-peaks in regions of high quality reads, which were interpreted as single nucleotide polymorphisms (SNPs), and not heterozygosis, because our primers amplify separate eg95 loci.
PLoS ONE Alerts: New Articles
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Genotyping was performed using restriction fragment length polymorphisms.
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Both position types occur in every crossbill population studied, so the maintenance of this polymorphism necessitates an evolutionary explanation.
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The researchers conducted a genome-wide association study and found several polymorphisms - single-letter DNA alterations - also known as "SNPs or" snips "- associated with reduced hemoglobin levels.
RedOrbit News - Technology
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Many of the 5000 or so bryozoan species exhibit polymorphism.
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Methods: Polymerase chain reaction-single strand conformation polymorphism(PCR-SSCP) was used to exclude known gene mutation of HGF from 2 familial gingival fibromatosis .
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In children, GSTM1 polymorphism seems to modify BU pharmacokinetics after intravenous drug administration. busulfan, hematopoietic stem cell transplantation, glutathione
Naturejobs - All Jobs
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The polymorphism at A-6G and G-217A sites in promotor region plays an important role in regulating the gene expression, and the products of keep close correlation with the level of blood pressure.
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His research seeks to elaborate the spatial context of niche-width theory to make more relevant the fitness strategy of polymorphism and include multiunit expressions of specialism and generalism.
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Objective To investigate whether the angiotensinogen AGT(M235T) gene polymorphisms might be implicated in essential hypertension(EH) in Sichuan Hans population.
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The situation of recurrent mutation is especially likely for a C / T polymorphism at the hypermutable CpG dinucleotides.
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The applications of karyotyping and restriction fragment length polymorphism (RFLP) analyses, specific DNA probes and PCR method to the diagnosis of Candida albicans infections are reviewed.
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Conclusion The 10 STR were verified as good genetic marker with high heterozygosities and polymorphism information content in Han population.
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The Object - Oriented characters, such as encapsulation, inheritance, polymorphism and dynamic binding etc, increase the testing complexity.
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Partly because of my reading-up on other areas of direct interest (like cryptic diversity [see previous post], the discovery of new species, declines in global biodiversity, Cretaceous biogeography, radical homoplasy, polymorphism, and evolutionary reversals), I am returning again and again to the salamander literature.
Archive 2006-03-01
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Methods LOH at APC and MCC genetic loci in 46 specimens resected from esophageal neoplasm was studied with polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP).
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Double reduction may play a significant role in plant evolution and the maintenance of genetic polymorphism in natural populations.
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In the subclass Hexacorallia, polymorphism of polyps in colonies is unknown, so for this group, variation in life cycles simply involves fission.
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Knowledge and understanding of various polymorphisms, including that of the 2 adrenoceptor and leucotriene C4 synthase, has led to the study of pharmacogenetic determinants that may influence the response to treatment in asthma.
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A more pressing concern is whether each of the two main populations are themselves produced by admixture between local populations, perhaps including inversion polymorphism types.
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Restriction fragment length polymorphism ( RFLP ) technique used in cancer research.
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Renin and atrial natriuretic peptide restriction fragment length polymorphisms: association with ethnicity and blood pressure.
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In section 3.2 we saw that compounds which exist in more than one crystalline form are said to exhibit polymorphism.
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The results presented below show that these two extremes produce very different patterns of polymorphism.
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Objective Polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP) assay was applied to molecular typing of resistance-associated esterase genes of Culex pipiens complex.
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In spite of the discovery that angiotensinogen (AGT) gene polymorphism is associated with essential hypertension, the genetics of this disease has remained poorly understood [58].
The 2007 Nobel Prize in Physiology or Medicine - Advanced Information
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Many of the 5000 or so bryozoan species exhibit polymorphism.
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METHODS:Polymerase chain reaction restriction fragment length polymorphism(PCR RFLP) was used to analyze NQO1 gene polymorphism in Parkinson disease group and healthy adult control group.
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Anthozoan life cycles are therefore simpler and their evolution centers on the presence or absence of clonality and the development of polymorphism of polyps in colonial forms.
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Microsatellite loci appear to be distributed throughout vertebrate genomes and can demonstrate high levels of intraspecific allelic polymorphism.
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Molar polymorphism is probably a primitive mammalian character, conserved in marsupials and mustelids.
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The polymorphism is common in many insect groups, most notably the Hemiptera / Homoptera (waterstriders, planthoppers and aphids), Coleoptera and, Orthoptera (crickets and grasshoppers).
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Some of the genetic polymorphism that existed in the ancestral populations was lost in the populations of the two lakes.
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What we were looking for was what we call a polymorphism—an unusual or abnormal form of a gene—that might prove to be associated with alcoholism.
Alcohol and The Addictive Brain
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Methods Single round Touchdown PCR (TD PCR) and restriction fragment length polymorphism (RFLP) method were used for genotyping in 110 people from the Han population in Chongqing.
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This is called polymorphism where a sub-type can be substituted in any situation where a parent type is expected i.e. the object can be treated as an instance of the parent class.
A Byte of Python
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He gave us the first quantitative theories of sexual selection, mimicry, polymorphism, evolution of recombination rates, and supergenes.
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Botanists have classically viewed this polymorphism as an outcrossing mechanism, since in most situations reciprocal morphs can only cross-fertilize.
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AFLP (amplified fragment length polymorphism) is a new DNA molecular marker technique with high efficiency, promptitude, stability and accuracy.
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The cDNA-amplified fragment length polymorphism approach was used to identify genes expressed differentially during early and late flower bud development in tea plant(Camellia sinensis).
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The selective maintenance of inversion polymorphisms has been the subject of abundant theoretical work.
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The glutelin electrophoretogram had abundant bands with stronger polymorphism and more characteristic hands, so it could effectively identify the differences between rape hybrid and parental lines.
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In the course of the study, we decided to include genetic polymorphisms of DNA repair genes.
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This magnificent enterprise has charted our species' path out of Africa using successive generations of markers: blood type, allozyme, mitochondrial DNA, the Y chromosome, and nuclear single nucleotide polymorphisms SNPs.
"On Human Diversity"
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ABSTRACT:Objective To explore the association between monoamine oxidase A (MAOA) variable number tandem repeat (VNTR) polymorphism and major depression in Chinese Han population.
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Gene mutation can occur at many levels - from single nucleotide polymorphisms, to the introduction of stop codons and longer stretches of DNA (whole genes, even) via intron/exon shuffling.
On Thursday, the Legg report will be published along with...
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ABSTRACT:Objective To explore the association between monoamine oxidase A (MAOA) variable number tandem repeat (VNTR) polymorphism and major depression in Chinese Han population.
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The doubling-up of parentheses in the way Verity describes is nothing more or less than an early form of polymorphism, as functions can also be seen as virtual arrays of infinite values.
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A representative set of 42 leucaena genetic resources from Thailand, USA(Hawaii), Mexico, Philippines, Clolmbia and China, were analyzed by amplified fragment length polymorphism(AFLP) methodology.
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And, templates can be used with inheritance for applications such as parameterized virtuality, which combines the best of two forms of polymorphism.
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You could then bring in the concept of a machine that 'composes' two other machines together, creating a machine that 'contains' both machines wired together somehow, as the next step.... and you'd probably have to discuss polymorphism at this point too....
Teaching Functional Programming To Kids
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The cluster analysis based on AFLP data of two different types showed that: the polymorphism between apomictic reproduction type and sexual type are little, the genetic relationship is very intimate.
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At each locus, polymorphism can be maintained provided that two conditions are met.
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The glutelin electrophoretogram had abundant bands with stronger polymorphism and more characteristic hands, so it could effectively identify the differences between rape hybrid and parental lines.
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The aluminium silicate minerals andalusite, kyanite, and sillimanite are good examples of this phenomenon of polymorphism.
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Polymorphisms produced by the remaining three probes (ANX1, CLTA, and POLR2E) all failed to map to the expected location and were suffixed with like1, like2, etc.
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In the final alignments spanning a total of 2626 bp, we observed 65 segregating sites, corresponding to 1 SNP per ~40 bp, which is in concordance with previously published levels of exonic polymorphism in the genus
PLoS ONE Alerts: New Articles
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ABSTRACT:Objective To explore the association between monoamine oxidase A (MAOA) variable number tandem repeat (VNTR) polymorphism and major depression in Chinese Han population.
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Objective To investigate the association among tryptophan hydroxylase(TPH) gene A218C polymorphism, unipolar depression(UPD) and symptom phenotypes in Han nationality of Chinese.
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Primary immunodeficiency diseases caused by genetic polymorphisms are now largely diagnosable with molecular probes.
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Adaptive strategies may often evolve, such as the biochemical polymorphisms of blood and serum groups.
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The study indicated that ISSR produced high polymorphism on tartary buckwheat. ISSR analysis can be used for the molecular evaluation and studies of genetic diversity of tartary buckwheat germplasm.
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The aim of this study was to characterize the molecular basis of the oncogenicity of CH-ES1 cells, we looked for abnormal chromosomal copy number (by array Comparative Genomic Hybridization, aCGH) and single nucleotide polymorphisms (SNPs).
PLoS ONE Alerts: New Articles
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We have studied different aspects of DNA sequence polymorphism within a single deme drawn from a population that has experienced a range expansion.
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Identification of the gene encoding s-ADH and the eventual search for polymorphisms are awaited with interest.
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RMI uses object serialization to marshal and unmarshal parameters and does not truncate types, supporting true object-oriented polymorphism.
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Typically, polymorphism in a sample is needed to perform those tests and estimate population parameters.
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It was thought that polymorphism between tandemly repeated genes suppresses recombination, thereby preventing sequence homogenization of the gene family.
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A new word such as polyformism may have to be coined, or an older word polymorphism may have to be invoked, to be set beside polytheism, to provide the corrective.
The Full Feed from HuffingtonPost.com
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Standard cytogenetic analysis including preparation of karyotypes, metaphase and interphase based fluorescence in situ hybridization (FISH), high resolution single nucleotide polymorphism oligonucleotide based array (SNP array) analysis and mutation analysis of the INI1/SMARCB1 gene are available.
Cancer Cytogenetics Lab
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I had not worked on genetics since, as a Cambridge undergraduate, I had published juvenilia on polymorphisms maintained by single locus selection.
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Being based on the colour of maternal tissue, this polymorphism necessarily has a modificatory basis.
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Objective To investigate whether the angiotensinogen AGT(M235T) gene polymorphisms might be implicated in essential hypertension(EH) in Sichuan Hans population.
