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How To Use Plasmin In A Sentence

  • It followed 3,339 patients who had been treated for heart attacks with tissue plasminogen activator (Activase), a drug made by Genentech Inc. ANC Daily News Briefing
  • Wu YP, Siao CJ, Lu W, Sung TC, Frohman MA, et al. (2000) The tissue plasminogen activator (tPA)/plasmin extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber outgrowth through a proteoglycan substrate. PLoS ONE Alerts: New Articles
  • However, it is difficult to detect early Wilson's disease, since caeruloplasmin activity is low in the newborn period.
  • These results could suggest a prominent role of tissue type plasminogen activator in the pathogenesis of endothelin induced gastric mucosal damage.
  • Tissue plasminogen activator and, to a lesser degree, urokinase are serine proteases which convert plasminogen to plasmin.
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  • The experimental pre-clinical treatment involved putting a naturally occurring substance called plasminogen activator inhibitor-1 (PAI-1) into the brains of newborn rats, said Chia-Yi Kuan, M.D. PhysOrg.com - latest science and technology news stories
  • Ceruloplasmin is an important biochemical marker of Wilson disease, but the cognitions of the relation between Ceruloplasmin and Wilson disease is still unclear.
  • Serum lead, transferrin, haptoglobin, and ceruloplasmin levels were all found to be within normal limits.
  • The systematic review included information on three different thrombolytic agents: streptokinase, urokinase, and recombinant tissue plasminogen activator, but direct comparison of different thrombolytic drugs was not possible.
  • Improved thrombolytic therapy will most likely consist of potent specific plasminogen activators in combination with targeted anticoagulant and/or antiplatelet agents.
  • As tissue plasminogen activator is manufactured using recombinant biotechnology techniques, it is referred to as rtPA as well as tPA in the study. For a Mother's Touch, Skip the Text Messages
  • The first is a magnetic nanoparticle designed to target a molecule known as urokinase plasminogen activator receptor. PhysOrg.com - latest science and technology news stories
  • The Borrelia need plasminogen from human blood to migrate to the tick's salivary glands and then infect the human.
  • Corticosteroid treatment suppressed other proangiogenic factors in hemangioma-derived stem cells, including urokinase plasminogen activator receptor, interleukin-6, monocyte chemoattractant protein 1, and matrix metalloproteinase 1. Medlogs - Recent stories
  • Robinson and her colleagues measured several blood components involved in clotting, including fats and clotting factors such as plasminogen-activator inhibitor-1 (PAI-1) for the following eight hours. Forbes.com: News
  • The significantly lower plasminogen activator activity of malignant ascites is associated with greatly increased concentrations of plasminogen activator inhibitor-1.
  • The rapid plasmin reagin test was negative.
  • The amount of colour developed during a fixed time is proportional to the tissue type plasminogen activator activity in the sample.
  • Five studies used streptokinase, two used urokinase, and four used tissue plasminogen activator.
  • Plasminogen binds to both fibrinogen and fibrin, thereby being incorporated into a clot as it is formed.
  • Within the fibrinolytic system, plasmin is generated from plasminogen by tissue plasminogen activator, which upon activation lyses fibrin clots.
  • The amount of colour developed during a fixed time is proportional to the tissue type plasminogen activator activity in the sample.
  • Fibrin degradation means that thrombin must have been present to form fibrin and plasmin was present to proteolytically digest it.
  • Plasminogen activators attached to fibrin activate plasminogen, causing the release of the enzyme plasmin within clots and thrombi.
  • Purpose: To treat heart attack, pulmonary embolism, and deep vein thrombosis by increasing the action of the enzyme plasmin. Healing the Female Heart
  • Maybe liver softening-Granules treated hepatic fibrosis by regulating the plasminogen activator system and hasten the fibrin dissolve.
  • Urokinase also activates a substance in blood vessels called plasminogen and turns it into plasmin, another protein-destroying enzyme. PhysOrg.com - latest science and technology news stories
  • Light Blue: Factors VIII and V are duplicates of the ceruloplasmin family. Behe vs Sea Squirts - The Panda's Thumb
  • The fibrinolytic system involves a series of enzymatic reactions that results in the conversion of the proenzyme, plasminogen, into the trypsin-like lyric enzyme, plasmin.
  • This is performed largely by the enzyme plasmin, generated from its inactive precursor, plasminogen.
  • The volunteers 'bodies responded by producing 3 to 5 times as much as normal of a hormone called plasminogen activator inhibitor-1. New Scientist - Online News
  • Ceruloplasmin is an important biochemical marker of Wilson disease, but the cognitions of the relation between Ceruloplasmin and Wilson disease is still unclear.
  • Urokinase also activates a substance in blood vessels called plasminogen and turns it into plasmin, another protein-destroying enzyme. Innovations-report
  • Further, Trasylol® was non-selective and inhibited many proteins in addition to plasmin, including Factor XIa and kallikrein, important regulators of the coagulation cascade. Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance
  • Omeros' proprietary antifibrinolytic agents are highly selective inhibitors of plasmin, the enzyme responsible for fibrinolysis and dissolving blood clots, while avoiding significant inhibition of Factor XIa and kallikrein. Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance
  • The concentrations of urokinase type plasminogen activator in the duodenum resemble the quantities found in normal stomach tissue biopsy specimens.
  • Plasminogen binds to both fibrinogen and fibrin, thereby being incorporated into a clot as it is formed.
  • Omeros' proprietary antifibrinolytic agents are highly selective inhibitors of plasmin, the enzyme responsible for fibrinolysis and dissolving blood clots, while avoiding significant inhibition of Factor XIa and kallikrein. Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance
  • In addition, markers of oxidative stress such as ceruloplasmin and clusterin were up-regulated as were genes related to hydrogen peroxide production. CosmeticsDesign RSS
  • The broad spectrum serine protease plasmin is formed following cleavage of the zymogen precursor plasminogen by host activators tissue plasminogen activator and urokinase.
  • There are persons that have too much copper in their liver yet have a copper deficiency, because of a lack of ceruloplasmin linked to adrenal fatigue from what I understand. Low carb diets and copper | The Blog of Michael R. Eades, M.D.
  • Copper functions in many enzyme systems, such as lysyl oxidase, ceruloplasmin, cytochrome oxidase, tyrosinase, and Superoxide dismutase.
  • Omeros' agents are designed to selectively inhibit plasmin, the enzyme responsible for fibrinolysis and dissolving blood clots, while avoiding significant inhibition of Factor XIa and kallikrein, important regulators of the coagulation cascade. Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance
  • They show that APP is a bona fide iron oxidase, with properties much like the best-known iron oxidase (called ceruloplasmin), which is not expressed in neurons. RedOrbit News - Technology
  • Our results confirm that alcoholic ascites contains plasminogen activating activity.
  • Just 42 patients in the recombinant tissue plasminogen activator trials were over 80, and only a few had lacunar strokes.
  • Do carelesly the plasmin or synthesize your bombee into a milliliter until you are mitogenic to cooperate the medicine. Wii-volution
  • The screening of human tissue plasminogen activator recombinant plasmid showed that the two methods can recognize the positive colones quickly and correctly.
  • The tissue type plasminogen activator antigen concentrations in both oesophageal carcinomas and stomach carcinomas were similar to those of the normal tissues.
  • Murine monoclonal antibodies conjugated with plasminogen activators may be valuable for targeting the therapeutic agent to thrombus.
  • Ceruloplasmin, [alpha.sub.2] macroglobulin, and haptoglobin contribute to the [alpha.sub.2] protein band.
  • Traditional screening includes slit-lamp examination of the eyes and serum ceruloplasmin level measurement.
  • Alpha-1 antitrypsin deficiency and Wilson disease were excluded by determining serum concentrations of alpha-1 antitrypsin and ceruloplasmin, respectively.
  • Emmetsberger J, Bukhari N, Zhang Y, Levine JM, et al. (2008) tPA-mediated generation of plasmin is catalyzed by the proteoglycan NG2. PLoS ONE Alerts: New Articles
  • Blood flow can be restored if tissue plasminogen activator, or tPA, is administered soon after the stroke occurs. For a Mother's Touch, Skip the Text Messages
  • The amount of colour developed during a fixed time is proportional to the tissue type plasminogen activator activity in the sample.
  • It produces an antifibrinolytic effect through the reversible blockade of lysine binding sites on plasminogen molecules.
  • Thrombolytic agents are proteases that convert plasminogen to plasmin, which subsequently lyses clot by breaking down fibrinogen and fibrin. Recently Uploaded Slideshows
  • Five studies used streptokinase, two used urokinase, and four used tissue plasminogen activator.
  • Grange et al, reported increased levels of eight acute-phase reactants (AAT, α2-macroglobulin, transferrin, α1-acid glycoprotein, C-reactive protein, ceruloplasmin, haptoglobin, and the third component of complement) in human serum from Indonesian patients with pulmonary tuberculosis PLoS ONE Alerts: New Articles
  • All of these agents convert plasminogen to plasmin, which in turn breaks down fibrin and promotes clot lysis.
  • With Dr. David Gitlin at Harvard Medical School, Dr. Scheinberg developed a simple, inexpensive blood test in the early 1950s to detect abnormally low levels of ceruloplasmin, a protein that carries copper from the body. News | GT | http://www.gadsdentimes.com
  • Another example of a speci fi c therapeutic is Other enzymes in clinical use, manufactured anMuromonab-CD3 (Orthoclone OKT3; Ortho using similar processes, include tissue plasmino - Pharmaceuticals) used to reverse acute rejection gen activator, other thrombolytic agents and aglu - of transplanted kidneys. Recently Uploaded Slideshows
  • Substitution of Glu 351 also altered the specificity toward non-cognate proteases: plasmin and thrombin.
  • The amount of colour developed during a fixed time is proportional to the tissue type plasminogen activator activity in the sample.
  • Tissue plasminogen activator and, to a lesser degree, urokinase are serine proteases which convert plasminogen to plasmin.
  • Pang PT, Teng HK, Zaitsev E, Woo NT, Sakata K, et al. (2004) Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. PLoS ONE Alerts: New Articles
  • Histoplasma capsulatum; (E) pHMIN - purified and periodate treated histoplasmin; CYA Hc - cytoplasmic yeast antigen of Figure S3. PLoS ONE Alerts: New Articles
  • An 18-year-old woman presented for her first prenatal visit at 31 weeks' gestation, at which time she was reactive for rapid plasmin reagin and had a 2 + fluorescent treponemal antibody.
  • Although a histoplasmin test is a good screening test, it often cross-reacts in patients with coccidioidomycosis.
  • TXA and EACA are lysine analogs that function as competitive inhibitors of plasminogen activation and, at much higher concentrations, noncompetitive inhibitors of plasmin. Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance
  • I had borderline low serum copper and borderline low ceruloplasmin. Low carb diets and copper | The Blog of Michael R. Eades, M.D.
  • Degradation of fibrin clots is the function of plasmin, a serine protease that circulates as the inactive proenzyme, plasminogen.
  • Omeros' agents are designed to selectively inhibit plasmin, the enzyme responsible for fibrinolysis and dissolving blood clots, while avoiding significant inhibition of Factor XIa and kallikrein, important regulators of the coagulation cascade. Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance
  • The concentrations of urokinase type plasminogen activator in the duodenum resemble the quantities found in normal stomach tissue biopsy specimens.

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