How To Use Photosensitize In A Sentence
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The topics of interest cover the use of light for therapeutic and diagnostic purposes - from fundamental principles to development and application - and extend to the interaction of light with biological material at the molecular, membrane, cell and organ levels (including phototoxicity and photosensitizer molecules and particles), as well as to novel optical imaging techniques (including functional imaging for applications in life sciences).
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The approach is called photodynamic therapy, or PDT, which uses light energy to activate a drug called a photosensitizer that produces a form of oxygen that kills nearby cells.
Sound Politics
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So, I joined the Society for Photographic Engineering and Technology, and started reading up on why certain things, such as photosensitized materials and their chemistry, worked.
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The induction of DNA single-strand breaks(ssb)by exposure to hematoporphyrin photosensitizer(PSD-007)followed by photoirradiation was observed in mice leukemia cells(L7712)in vitro.
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This finding provides support for the ongoing development of more solubilized versions of lutetium texaphyrin as photosensitizers for use in the diagnosis and PDT of cancerous disease.
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The specificity of the PDT effect correlates with the distribution and concentration of the photosensitizer in the tumor.
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Upon irradiation with laser light (680 nm), a photosensitizer in the donor bead converts ambient oxygen to singlet-state oxygen.
The Scientist
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They all need the sun to photosensitize their venom.
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By contrast, the formation of photosensitized frank scissions, which must arise from sugar oxidation, is not usual.
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In a series of studies, they have shown that photosensitizers that localize in mitochondria are very efficient inducers of apoptosis.
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The antitumor properties of St. John's wort are attributed to hypericin, which is a powerful photosensitizer.
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A low power laser warms the targeted tissue and releases a bolus of photosensitizer.
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The majority of photosensitizers are derivatives of hematoporphyrin, a synthetic porphyrin synthesized from heme.
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I suspect the weapon is also photosensitized to detonate under a high-intensity beam of light.
The Pandora Principle
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It appears as a result of the photosensitized formation of free radicals, singlet oxygen, photoproducts or other intermediates.
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The majority of photosensitizers are derivatives of hematoporphyrin, a synthetic porphyrin synthesized from heme.
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For all formulations tested, uptake of photosensitizer into cells was dependent on concentration, time and temperature.
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This appears to work well for photosensitizers that are delivered intravascularly and then diffuse out into the parenchyma and localize in the cellular spaces.
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Again, this will need to be incorporated into clinical protocols, although it is noted that other photosensitizers and antineoplastic drugs in common use, such as paclitaxol, also use similar excipients.
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These efforts have successfully identified mitochondria, lysosomes and various cytoplasmic membranes as among the primary targets of PDT-mediated damage, depending on the particular photosensitizer.
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Test is made to antioxidation activity of extracts of Plumbago Zeyanica L. by ESR method, photosensitized compound microbiological method and photometric method.
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Objective:To introduce a new therapy combining percutaneous laser and photosensitizer in treatment of portal vein tumor thrombus(PVTT), and evaluate the efficacy and validity of the method.
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An enormous number of naturally occurring and synthetic compounds are known to be photosensitizers commonly used in photobiological studies.
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In photochemistry and photobiology, it is often assumed that the noncovalent association of a photosensitizer to its target will lead to more effective damage because diffusion-limited processes are eliminated.
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The photosensitizer used in this study was benzoporphyrin derivative monoacid ring ‘a’ as supplied in a lipid formulated preparation under the generic name verteporfin.
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Photoproduct levels may reflect the net photochemical effects of light and oxygen within tissue on native photosensitizers.
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Warm California sunlight poured in through the photosensitized windows, gilding everything inside from furniture to flowers.
Jed the Dead
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Furthermore, the extent of photosensitizer distribution and penetration into the spheroids was examined.
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Hypericin, a polycyclic quinone obtained from plants of the genus Hypericum, has been shown to be a promising photosensitizer.
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We wished to evaluate the efficacy of Pul8 photosensitizer in the induction of apoptosis because its anhydride group may provide the possibility of coupling this photosensitizer to cell-targeting agents like antibodies.
