How To Use Penicillin In A Sentence
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Penicillin was an extremely significant medical discovery.
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Streptomycin is more stable than penicillin and so it was easier to isolate and manufacture.
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Currently, many pneumococci are resistant to penicillins and other agents.
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- Antibacterial (antibiotic) of the penicillin group, acting specifically against penicillinase producing staphylococci
Chapter 4
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Like Harry Lime, the penicillin-diluting racketeer he plays in the film, Welles infects The Third Man from opening titles to closing credits.
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The discovery of penicillin was a landmark in the history of medicine.
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The invention of penicillin effectively wiped out the staph infection problem in hospitals, but after the bacteria developed resistance to it, methicillin became the standard treatment in 1960.
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We therefore assessed penicillin resistance against the prescribing of phenoxymethylpenicillin, all penicillins, and all lactams, and erythromycin resistance against the prescribing of erythromycin and all macrolides.
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In an almost-standard sandwich-type configuration, penicillinase enzyme was attached to the target cells using anti-penicillinase and bridging antibodies.
The Scientist
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Since 1948 his research topics have included carbohydrate-amino acid relationship in nervous tissue, a study of the mode of action of insulin, fermentation technology, 6-aminopenicillanic acid and penicillinase-stable penicillins, lysergic acid production in submerged culture, and the isolation of new fungal metabolites.
Ernst B. Chain - Biography
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In its early stages, leptospirosis can be treated with antibiotics such as penicillin, streptomycin, tetracycline and erythromycin.
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For the patient who is allergic to penicillins, the use of trimethoprim/sulfamethoxazole is indicated.
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penicillin was an important discovery
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In 1909 Ehrlich and Hata finally achieved success with the 606th experimental compound, patented under the name "Salvarsan" and later known as arsphenamine; in modified form, the drug remained the mainstay of syphilis treatment until the discovery of penicillin.
ArchivesBlogs
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Penicillin, in fact, saved so many lives in its early days that statues of Alexander Fleming were erected at many bullrings around Spain.
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Encouraged by the discovery of streptothricin and stimulated by the triumphal development of penicillin treatment, the research team headed by Dr. Waksman continued their untiring search for new antibiotic-producing microbes.
Nobel Prize in Physiology or Medicine 1952 - Presentation Speech
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Although popular mythology credits Alexander Fleming, it was Florey and his team who gave the world the miracle drug, penicillin.
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Unlike Streptococcus pneumoniae, group A beta-hemolytic streptococci have not developed resistance to penicillins.
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The liver is also actively involved in detoxifying and excreting into the bile many different drugs, including sulfonamides, penicillin, ampicillin and erythromycin to name a few.
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The design is penicillin factory with an annual output of 500 tons of the preliminary design.
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Later, we also grew crystals of potassium and rubidium benzyl-penicillin, hoping again for isomorphous series.
Nobel Lecture The X-Ray Analysis Of Complicated Molecules
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Exanthematous eruptions most commonly occur in association with the administration of penicillins or cephalosporins.
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Treatment consisted of cleaning and bandaging the wound and administering injections of nikethamide to reduce shock and penicillin to prevent infection.
DEPARTMENT OF DEFENSE INTELLIGENCE REPORT
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Treatment then consists of finding an acceptable substitute and avoiding penicillin.
An Alternative Approach to Allergies
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All the 300 strains were resistant to oxacillin and penicillin and susceptible to rifampicin and vancomycin.
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Penicillin was an extremely significant medical discovery.
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- The combination of probenecid and procaine penicillin is always indicated for the treatment of gonorrhoea, except in pregnant women.
Chapter 4
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No government forces a hospital to give penicillin to a patient who has pointed out that he is allergic to it.
Times, Sunday Times
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An example would be the bacteria that secrete penicillinase, which is an enzyme that destroys penicillin.
Cities In Flight
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Most of our "medically important" antibiotics, like penicillins, tetracyclines and erythromycins, are used in animals, not people.
David Wallinga, M.D.: Feeding Animals Antibiotics: Not Helping U.S. Meat Export
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Penicillin was acclaimed as the most important discovery during the 1940's.
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As the streptococci are now resistant to penicillin the treatment fails.
Times, Sunday Times
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Enterococci are inherently resistant to cephalosporins, semi-synthetic penicillins, and clindamycin.
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They include many human antibiotics, penicillins and some names I recognise from the bad days of the European fish-farming industry -- nitrofuran, chloramphenicol and organophosphate pesticides.
Chinalyst - China blogs in English
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Penicillin also kills corkscrew organisms such as the spirochete of syphillis.
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So within a short time, there will be millions of germs resistant to penicillin.
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Results the Penicillin G Benzathine injection had mild allergy effect and no muscle stimulation.
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Stepping back a generation, doctors were familiar with hospital wards full of patients succumbing to sepsis in the pre-penicillin era.
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Another accidental discovery was penicillin.
Times, Sunday Times
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In its early stages, leptospirosis can be treated with antibiotics such as penicillin, streptomycin, tetracycline and erythromycin.
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Therefore it is necessary to treat breast infections with a penicillinase-resistant antibiotic such as either flucloxacillin or erythromycin.
Chapter 39
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The antibiotics used were mainly cephalosporins, penicillins, fluoroquinolones, aminoglycosides, tetracyclines and antituberculosis drugs.
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If antibiotics are required, one that is active against gram-positive organisms such as penicillinase-resistant penicillins, cephalosporins, macrolides, or fluoroquinolones should be chosen.
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Penicillins, cephalosporins, monobactams and carbapenems can all be hydrolyzed by multiple members of the beta lactamase family of enzymes, resulting in a microbiologically ineffective compound.
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- Metronidazole can be used as an antibiotic, under medical supervision, with the same dose used for amoebiasis treatment and combined with penicillin or ampicillin for 6 to 10 days.
Chapter 4
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Used with some antibiotics of the penicillin family, probenecid increases the amount of penicillin in the blood and makes it last longer, increasing the effectiveness of treatment.
Chapter 37
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The curative treatment recommended for endocarditis combines penicillin or amoxicillin with gentamicin.
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A myth has grown up that he blundered into his discovery and did not realise the true potential of penicillin, leaving others to exploit it.
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For example, the resistance to penicillin initially was due to production of an enzyme penicillinase by bacteria, antibiotics like cloxallin were developed which was resistant to penicillinase enzyme.
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The lactams are a family of antimicrobial agents consisting of four major groups: penicillins, cephalosporins, monobactams, and carbapenems.
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Penicillin is made up of plant material that the body can absorb.
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The surprising finding was that people who had reacted to sulphonamides were more likely to react to penicillins than to sulphonamide non-antibiotics.
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We specialize in supply streptomycin, penicillin and other pharmacopoeia material below market price.
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The patient had an allergy to penicillin.
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Major classes of antibiotics include tetracyclines, aminoglycosides, penicillins, cephalosporins, fluoroquinolones, streptogramins, sulfonamides, and erythromycins.
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The pdb-codes of the proteins are as follows: endonuclease III - 2ABK, dihydrodipicolinate synthase - 1DHP, blue copper oxydase CuoE - 1KV7, threonine dehydratase - 1TDJ, penicillin amidase - 1PNK.
PLoS ONE Alerts: New Articles
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All the 300 strains were resistant to oxacillin and penicillin and susceptible to rifampicin and vancomycin.
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Of 27 penicillin-resistant strains, 10 (37\%) were resistant to erythromycin, 8 (29. 6\%) to cefotaxime, 2 (7. 4\%) to levofloxacin, and 4 (14. 8\%) were identified as multidrug resistant.
BioMed Central - Latest articles
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Penicillin was an extremely significant medical discovery.
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The study continued to be funded by the government long after penicillin was available as a cure.
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Most common and most easily curable with penicillin and other antibiotics is the cutaneous form, observed among people who come into contact with contaminated hides, hair, or bonemeal or who butcher infected animals.
Inaccrochable
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And that was the area of some of the first campaigns, the mass campaigns for penicillin, the yaws eradication.
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Another accidental discovery was penicillin.
Times, Sunday Times
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Penicillin is a very useful drug for humans but kills guinea pigs and hamsters.
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Penicillin kills most gram negative cocci that cause gonorrhea and epidemic spinal meningitis.
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The effect on people of consuming over a lifetime tiny quantities of penicillin, neomycin and other drugs left over in meat is little studied.
Antibiotics in Pork Draw More Scrutiny By Inspectors
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The discovery of penicillin was a landmark in the history of medicine.
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Caught in time, a penicillin injection from a GP can be life-saving.
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Patients who are allergic to penicillin can be treated with erythromycin or first-generation cephalosporins (if there is no immediate-type hypersensitivity to beta-lactam antibiotics).
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Penicillin is the agent of choice for intrapartum antibiotic prophylaxis.
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Treatment then consists of finding an acceptable substitute and avoiding penicillin.
An Alternative Approach to Allergies
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Axe’s numbers tell us about the apparent isolation of the low-activity variant, but reveal little nor can it be expected to about the “isolation” or evolution of TEM-1 penicillinase.
Axe (2004) and the evolution of enzyme function - The Panda's Thumb
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Our trial was not designed to study whether penicillin would prevent quinsy or peritonsillar cellulitis.
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Basic drugs were available throughout the study period but affordable antibiotics for example, such as penicillin, chloramphenicol, and gentamicin were normally used.
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Medical breakthroughs, including sulfa drugs, penicillin, and quinine, were also a consequence of the war.
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However, just as with penicillin and the tetracyclines in the past, vets are now simply prescribing more macrolides generally to make up for the ban on tylosin as a growth promoter.
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This has been shown to occur with penicillin, valproic acid, quinidine, sulfonamides, cimetidine and heparin.
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A coolie grabbed a handful of penicillin from a shelf.
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Significant changes were observed in morphological and cultural characteristics of variants with decreased susceptibility to penicillin.
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The sift did not reveal any deletions that make cells susceptible to amoxicillin, penicillin, rifampin or vancomycin, which are used to treat bacterial infections of the airways, stomach and skin.
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Reports have documented postcoital allergic reactions including asthma in female subjects due to ingestion of walnut, vinblastine, thioridazine, and penicillin by the male partner before coitus.
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Before I discovered I wasn't cut out to be a bench biochemist, my undergraduate research was on "Competitive inhibition of penicillinase by notalysin, a
Citizendium, the Citizens' Compendium - Recent changes [en]
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May 22, 2006, 5: 36 pm buy penicillin says: buy penicillin skimp coroner fraternities campers freed phototypesetter
The Volokh Conspiracy » More about “Banning” the Bible:
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Penicillin produced a revolution in medicine.
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Novexel 104 inhibits several classes of bacterial enzymes called beta-lactamases, that break down beta-lactin antibiotics such as Cephalosporin, Penicillin and Carbapenem.
Forest Laboratories Inc. Management Discusses F2Q2011 Results - Earnings Call Transcript -- Seeking Alpha
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C. Resistance to penicillin is mediated both by plasmid-encoded penicillinase and by changes in chromosome-encoded proteins that control the permeability of the drug.
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However, antibiotics most likely to cause severe allergic reactions (e.g., penicillins, cephalosporins and sulfa drugs) are not contained in vaccines.
Antibiotics
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The violations occurred over a number of years, as recently as 2008, and involved 23 positive tests for drugs such as neomycin, penicillin, gentamicin and other antibiotics.
Health News from Medical News Today
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It is also a bactericidal agent among other antimicrobial agents, such as penicillin, sulfa, and tetracycline.
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For this reason many doctors now routinely prescribe certain antibiotics, namely erythromycin or penicillin, for any woman who gets pregnant and has a history of repeated miscarriage.
Getting Pregnant
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Penicillin was acclaimed as the most important discovery during the 1940's.
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Penicillin was acclaimed as the most important discovery during the 1940's.
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Antibiotic categories to consider include penicillins, cephalosporins, and macrolides.
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Most work by interfering with metabolic pathways that are unique to bacteria - eg, penicillin weakens bacteria cell walls but has no effect on human tissue.
Times, Sunday Times
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She injected the patient with penicillin.
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Computers have not really changed the world, not the way railways did or penicillin.
Times, Sunday Times
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The central nucleus of all these penicillins was the same, but the exact structure was established only after much controversy.
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Numerous death have occurred from anaphylaxis after the injection of penicillin.
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These results suggest that penicillin can be given safely to patients with negative intradermal skin tests to penicillin.
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A control gene regulates the production of an enzyme that destroys the antibiotic, e.g. penicillinase which destroys penicillin.
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The search engines would not have realized, as did Sir Alexander Fleming, that the penicillium mold forming on some accidentally spilled rye bread crumbs and preventing staphylococcus bacteria from growing in his Petrie dish could herald the discovery of the life-saving antibiotic, penicillin.
Marshall P. Duke: Pancake People, Rise Up!
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She was also seen by the doctor and was also given the drug amoxicillin, which is part of the penicillin family of medicines, despite telling him she was allergic to penicillin, the hearing was told.
The Asian News - RSS feed
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Penicillin interactions between statistical, fi nancial and psy - has three adverse events of primary interest (ana - chological aspects of trial design have been hinted phylaxis, bacterial drug resistance and sodium load at.
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After much prodding, he related that he had been taking a combination of penicillin and sulfa antibiotics, which he had purchased without a prescription ‘in the fish medication aisle’ of a local pet store.
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She was later treated with a penicillin-based drug despite her allergy being documented in her case notes.
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The discovery of penicillin was a landmark in the history of medicine.
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Without a cell wall the organism is resistant to the effects of penicillin and other beta-lactam antibiotics, which disrupt bacterial cell walls.
This Season���s Mean Mycoplasma ��� Sketching Our Turn With Atypical Pneumonia
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Fleming discovered penicillin by accident in 1928.
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In sum, while the CGMP regulations would not prohibit decontamination and conversion, the difficulty of cleaning up penicillin residues makes the chore daunting.
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Penicillin was first used in the early 1940s and by 1950, most Staphylococcus aureus organisms were resistant to the drug by virtue of elaboration of a penicillinase enzyme.
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The funguses in which penicillin was discovered use it to kill bacteria which might compete with them for food.
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Fleming discovered penicillin by accident in 1928.
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Studies from the late 1960s and the 1970s revealed that streptococcal eradication was equal with intramuscularly and orally administered penicillins.
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However, one kind of sore throat - called strep throat - should be treated with penicillin.
Chapter 28
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She was not convinced the drug was to blame, but she agreed to authorize a different prescription—a sulfonamide, a drug class that has been on the market even longer than penicillin.
SUPERBUG
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It also produces raw materials and finished products of antibiotics, such as penicillin and rifampicin.
Times, Sunday Times
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· Use an antibiotic such as tetracycline, ampicillin, or penicillin.
Chapter 20
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Medical breakthroughs, including sulfa drugs, penicillin, and quinine, were also a consequence of the war.
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The patients had been treated with ampicillin, penicillin, or chloramphenicol.
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That is partly because it is a glycopeptide, a separate class of drug from penicillin and methicillin.
SUPERBUG
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The factors that may have been responsible were, first, sulfonamide and penicillin for infection; second, ergometrine use to reduce postpartum hemorrhage; third, universal blood transfusion; and fourth, much better cooperation and better medical education and so on.
Doctor Resigns From Hospital Because She Won’t Do Unneeded C-Sections
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Drugs that have been implicated include penicillin, aminopenicillins, sulfonamides, allopurinol, thiazides, quinolones, hydantoins, and propylthiouracil.
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Many were originally sensitive to antibiotics such as penicillins, but overuse of these drugs has resulted in many multi-resistant bacteria.
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Some antibiotics, such as gentamicin, penicillin G, tetracycline, methicillin, erythromycin, and vancomycin, are not compatible with heparin.
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Some strains have become resistant to antibiotics used heavily in the past including penicillin, tetracyclines, ciprofloxacin and cefixime.
The Sun
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Oral antibiotics are usually used in the treatment and include first-generation cephalosporins, penicillinase-resistant penicillins, macrolides, and fluoroquinolones.
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Treatment then consists of finding an acceptable substitute and avoiding penicillin.
An Alternative Approach to Allergies
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All the usual range of antibiotics, penicillins and cephalosporins are pretty much useless against these things.
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They also have a "zesty" chicken soup called avgolemono that they bill as traditional "greek penicillin".
Recent Reviews Near San Francisco, CA
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A single injection of penicillin can cure syphilis if the woman has had the infection for less than one year.
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Intestinal absorption of penicillin, captopril, ciprofloxacin, quinidine and zidovudine was reported to be reduced when given with food.
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For example, in some parts of the world pneumococci remain predictably sensitive to penicillin, and this drug can remain a first line agent for presumed pneumococcal meningitis, but we do not know how long this will be true.
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Yeasts have been used for centuries by peoples worldwide to ferment sugar to alcohol; the drug penicillin was found in a mould.
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Resistance can lead to the creation of a superbug and is one of the reasons penicillin has traditionally been used.
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Major classes of antibiotics include tetracyclines, aminoglycosides, penicillins, cephalosporins, fluoroquinolones, streptogramins, sulfonamides, and erythromycins.
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ANTIBIOTICS IN SEPSIS 2 Monotherapy with carbapenem antibiotics = β-lactam and an aminoglycoside (Netspan) Extended spectrum carboxypenicillins or ureidopenicillins combined with beta lactamase inhibitors (Tazact) have been shown to be effective for the treatment of suspected infections in febrile, neutropenic cancer patients and in patients with peritonitis or nosocomial pneumonia.
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Drugs that have been implicated include penicillin, aminopenicillins, sulfonamides, allopurinol, thiazides, quinolones, hydantoins, and propylthiouracil.
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Penicillin was once expensive too — so rare and expensive that it was filtered from the urine of the first patient for reinjection.
The Volokh Conspiracy » “Fannie Mae Health Care”:
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A combination of penicillin or ampicillin with gentamicin is appropriate for endocarditis caused by enterococci that are not highly resistant to penicillin.
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Penicillin was an extremely significant medical discovery.
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the last issue of penicillin was over a month ago
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It is also a bactericidal agent among other antimicrobial agents, such as penicillin, sulfa, and tetracycline.
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OBJECTIVE To improve the HPLC method for identification and determination of Penicillin V potassium Tablets.
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Several drug classes that have lost their punch against the worsening strain include families that contain: penicillin, erythromycin, clindamycin, tetracycline and fluoroquinolone drugs such as Cipro, said Binh Diep, researcher at the University of California at San Francisco and first author of the study in the Annals of Internal Medicine.
Resistance of Superbug Grows
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She fell into a coma after being given penicillin, despite being acutely allergic to it.
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Overuse of antibiotics has been shown to drive the evolution of mutant strains of bacteria immune to a broad spectrum of drugs, including penicillins, cephalosporins, and quinolones.
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Other fungi provide numerous drugs (such as penicillin and other antibiotics), foods like mushrooms, truffles and morels, and the bubbles in bread, champagne, and beer.
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There were now several classes of antibiotics, from the penicillin derivatives to the sulfa drugs, the tetracyclines, erythromycin, and the antituberculosis drug streptomycin.
SUPERBUG
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I can relate some real horror stories about when my Dad was in practice - internal medicine - when he encountered people that "pilled" their children to avoid disease by feeding them penicillin and sulfa drugs.
Propeller Most Popular Stories
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Both boys were taken to York Hospital and have been put on a course of penicillin as a precaution.
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After performing aspiration, appropriate antibiotic therapy (including penicillin, clindamycin, cephalosporins, or metronidazole) must be initiated.
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Drugs cached on the national dinner plate may include antibiotics like penicillin, florfenicol, sulfamethazine and sulfadimethoxine, the anti-parasite drug Ivermectin, the non-steroidal anti-inflammatory drug flunixin and heavy metals says OIG, which oversees
AlterNet.org Main RSS Feed
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Conclusion: Cefradine aseptic screening and penicillin to eliminate enzyme inhibition, sterility test to ensure the accuracy of nature.
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The 2011 version turns out to be resistant to eight classes of antibiotics, including penicillin, streptomycin and sulfonamide.
Gene Probe Yields E. coli Clue
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Enterococci are inherently resistant to cephalosporins, semi-synthetic penicillins, and clindamycin.
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While the incidence of true cross-reactivity between penicillins and cephalosporins is low, the possible reactions include anaphylaxis, which can be fatal.
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The curative treatment recommended for endocarditis combines penicillin or amoxicillin with gentamicin.
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Now that we know that this microbe is sensitive, you have a generic drug called doxycycline, as well as generic penicillin that is quite effective against this.
CNN Transcript Oct 28, 2001
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Penicillin was acclaimed as the most important discovery during the 1940's.
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This has been shown to occur with penicillin, valproic acid, quinidine, sulfonamides, cimetidine and heparin.
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It is also a bactericidal agent among other antimicrobial agents, such as penicillin, sulfa, and tetracycline.
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Conclusion: Cefradine aseptic screening and penicillin to eliminate enzyme inhibition, sterility test to ensure the accuracy of nature.
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Neil was peeved when I refused his request for a prescription for penicillin.
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When the synapses of these inhibitory neurons are blocked by drugs (such as of picrotoxin or penicillin), the excitatory network can sustain a chain reaction leading to an epileptiform discharge.
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Consider a penicillinase-resistant penicillin (such as methicillin or nafcillin) or vancomycin plus an aminoglycoside or aztreonam.
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Penicillin or amoxicillin-clavulanate potassium is recommended for use in nonallergic patients with dog bites.
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Chemical mutagens or serial passages were employed earlier to decrease susceptibility to penicillin in BHS group A strains.
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They include chlortetracycline, erythromycin, neomycin, oxytetracycline, penicillin, and penicillin/streptomycin.
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Sometimes a secondary bacterial infection of the tonsils occurs, and this is usually treated with the antibiotic penicillin.
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Other antibiotics like penicillin and vancomycin slow the bacteria's ability to manufacture cell walls.
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It is well established that far less expensive antibiotics, including the penicillins and tetracyclines, are highly effective against Anthrax.
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A broad-spectrum antibiotic such as tetracycline kills many kinds of bacteria, while a narrow-spectrum antibiotic like penicillin kills only a few kinds of bacteria.
Chapter 8
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At present, the most effective strategy available to deal with S. pyogenes is treatment of acute infections by administration of therapeutic doses of a broad-spectrum antibiotic like penicillin.
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This has been shown to occur with penicillin, valproic acid, quinidine, sulfonamides, cimetidine and heparin.
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As an interne, I had not heard of sulfanilamide or penicillin; in my own specialty the anti-psychotic drugs or electro-convulsive therapy had not been introduced.
Medicare in Canada
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The man was dying, emaciated and had a high fever when the first injection of their scant supply of penicillin was given.
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The first thing I learned was that to make penicillin, you have to grow a mold called penicillium.
Phineas L. MacGuire . . . Gets Slimed!
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Staphylococcus aureus (MRSA), resulting in the concept that MRSA has emerged on a few occasions after penicillinase-stable β-lactam antibiotics were introduced to clinical practice, followed by intercontinental spread of individual clones.
Proceedings of the National Academy of Sciences current issue
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This proposal has been addressed very positively by industry. penicillin some drugs have retained excellent activity against particular target organisms, such as the penicillin against Streptococcus agalactia despite extensive use for 40 years. development of resistance to animal antimicrobials may present a hazard to humans when the resistant bacteria can cause disease in humans and can be transmitted via contaminated food.
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The development of penicillin during World War II added the last "A" to modern surgery's triad of anesthesia, asepsis, and antibiotics.
Gowns, Germs and Steel
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Drugs that have been implicated include penicillin, aminopenicillins, sulfonamides, allopurinol, thiazides, quinolones, hydantoins, and propylthiouracil.
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The next morning grandma was worse and the labs called to say that the pneumococcus was present in both specimens and that it was resistant to penicillin.
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buy penicillin skimp coroner fraternities campers freed phototypesetter
The Volokh Conspiracy » More about “Banning” the Bible:
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Because mono is caused by a virus, antibiotics such as penicillin won't help unless the child has a secondary infection like strep bacteria.
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Penicillin was a revolutionary drug.
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Prompt serology examination and penicillin treatment are the keys to cure ocular syphilis.
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Recall that Axe did not work with the native TEM-1 penicillinase, but rather with a variant that had a lower activity.
Axe (2004) and the evolution of enzyme function - The Panda's Thumb
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Penicillin also kills corkscrew organisms such as the spirochete of syphillis.
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The sift did not reveal any deletions that make cells susceptible to amoxicillin, penicillin, rifampin or vancomycin, which are used to treat bacterial infections of the airways, stomach and skin.
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Some antibiotics, such as gentamicin, penicillin G, tetracycline, methicillin, erythromycin, and vancomycin, are not compatible with heparin.
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Oral contraceptive failure may occur with the concomitant use of griseofulvin, rifampicin, and other antibiotics, especially aminopenicillins e.g.
Hello Ginette 35 meet Risma 17 You are going to make her Blind
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The following results emerge by simply reformulating the research question as: what is the benefit of an additional four days of penicillin treatment, after the initial three days?
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Many sorts of bacteria are resistant to penicillin.
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These chemically modified penicillins have a side chain that inhibits the action of penicillinase.
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When taken with probenecid, the amount of penicillin in the blood increases and lasts longer making the treatment more effective.
Chapter 37
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Beta-lactam antibiotics include methicillin and other more common antibiotics such as oxacillin, penicillin and amoxicillin.
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The object of interest was the so-called large domain of the TEM-1 penicillinase, an enzyme that breaks down antibiotics related to penicillin.
Axe (2004) and the evolution of enzyme function - The Panda's Thumb
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Identifying penicillia is relatively easy for a trained microbiologist; certifying that the substance ‘dissolving’ bacteria on petri dishes is true penicillin is quite a different matter.
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Penicillin, for instance, prevents the final cross - linking step, or transpeptidation, in the macromolecule's assembly.
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penicillin-resistant bacteria
