How To Use Ototoxic In A Sentence
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The risk of ototoxicity is not as much of an issue with the intact tympanic membrane.
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For example, some antibiotics can be ototoxic, causing serious ear damage to humans.
Nicholas D. Kristof
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One, the kind that can happen to anyone, is called phototoxic, the effects of which resemble a very bad sunburn.
NYT > Home Page
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Antibiotics such as tetracycline and sulfamethoxazole (Bactrim), some diuretics and antihistamines (such as Benadryl), nonsteroidal anti-inflammatory drugs (Feldene, Naproxen, Motrin), and some antidepressants can be phototoxic after exposure to UV light.
Simple Skin Beauty
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Most of the written description details the inventors’ testing ofloxacin on guinea pigs and their findings that ototoxicity did not result from the use of their compound.
Erroneous "Skill in the Art" Triggers Obviousness
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Moreover unlike small organic fluorescent molecules, GFP evolved over the eons to have relatively low phototoxicity.
NIH Public Access - Seeing Circuits Assemble
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Hartely et al. found that 1,5-and 1,8 - disubstituted aminoanthraquinones are phototoxic to human leukemic cells.
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Furthermore, the limited excitation region reduces phototoxicity because photodamage is largely confined to the focal volume.
Undefined
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These include: head injuries like skull fracture, whiplash injury and closed head injury metabolic disorders like hyperlipidemia, vitamin B12 deficiency and thyroid disorder ototoxicity to medications like aspirin presbycusis or hearing loss associated with age earwax impaction hypertonia or muscle tension circulatory problems like hypertension, atherosclerosis and malformation of capillaries
MyLinkVault Newest Links
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The topics of interest cover the use of light for therapeutic and diagnostic purposes - from fundamental principles to development and application - and extend to the interaction of light with biological material at the molecular, membrane, cell and organ levels (including phototoxicity and photosensitizer molecules and particles), as well as to novel optical imaging techniques (including functional imaging for applications in life sciences).
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It should be useful for scientists involved in developing new assays or in testing phototoxicity effects of various xenobiotics.
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The phototoxic activity of this porphyrin is mainly mediated by the impairment of the enzymic and transport functions of both the outer and cytoplasmic membranes.
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My father suffered severe hearing loss due to an ototoxic drug antibiotic and my ORL advised me to claim I have an allergy to aspirin, rather than argue with Anglo-saxon 'doctors'.
Yahoo! News: Business - Opinion
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Exposure to solvents alone significantly increased the risk for hearing loss, most likely the result of ototoxic effects along the auditory pathway.
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These include: head injuries like skull fracture, whiplash injury and closed head injury metabolic disorders like hyperlipidemia, vitamin B12 deficiency and thyroid disorder ototoxicity to medications like aspirin presbycusis or hearing loss associated with age earwax impaction hypertonia or muscle tension circulatory problems like hypertension, atherosclerosis and malformation of capillaries
MyLinkVault Newest Links
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Our data favor the use of chemotherapy regimens that contain 20 mg/m2 cisplatin per day to limit ototoxicity.
PhysOrg.com - latest science and technology news stories
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Chloroquine-related ototoxicity is considered to be rare.
One Downside - Travel in Mexico
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Ultraviolet treatment of the lens is, however, not possible in a clinical setting because of retinal phototoxicity Instead, we chose to explore a multiphoton approach where ultraviolet-like effects are obtained in confined space using infra-red light that is less harmful to the retina
PLoS ONE Alerts: New Articles
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That phototoxic effect makes the skin red, swollen, and irritated, then causes it to peel.
Simple Skin Beauty
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Other than regular golf, he had no history of prolonged occupational or recreational exposure to loud noises (such as shooting) or exposure to ototoxic substances to account for this noise induced loss.
Medlogs - Recent stories
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For example, aquatic organisms that have ingested UV-B-absorbing PAHs have been shown to exhibit phototoxic effects following exposure to UV-B radiation [99].
Potential impacts of direct mechanisms of climate change on human health in the Arctic
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These medications must be administered carefully in patients who are elderly, have poor renal function, require a prolonged course of medication, or require simultaneous administration of multiple ototoxic agents.
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At these higher doses gentamicin is non-selective and extremely toxic to humans, with irreversible hearing loss (ototoxicity) being the main negative consequence.
Health News from Medical News Today
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For the ototoxic cream, prepare a principal lasix vials (about 1/16 inch) of pirbuterol to the swallowed area (s).
Wii-volution
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Her chest x-ray and systemic symptoms were improving, but she was experiencing some ototoxicity.
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This process that damages the ear is called ototoxicity, using the antibiotic neomycin.
News-Letter
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Furthermore, there are other limitations in fluorescence microscopy, such as phototoxicity and imaging setup complexity.
PLoS ONE Alerts: New Articles
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Do not stop taking medications without consulting with your health care professional about the possible ototoxic impact of your medications.
Undefined
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The rise of two-photon imaging has allowed the study of the live brain tissues in situ over periods of days to months with little or none of the phototoxicity effects that limited previous methods.
NIH Public Access - Seeing Circuits Assemble
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Second, confocal detection is inherently inefficient, often requiring more illumination of the live specimen than it can endure before bleaching or phototoxicity occurs.
NIH Public Access - Seeing Circuits Assemble
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Infants at high risk for hearing loss are those with a family history of hereditary childhood sensorineural hearing loss, hyperbilirubinemia, ototoxic medications, bacterial meningitis, birth weight of less than 1500 grams (3.3 pounds), in-utero infections, craniofacial abnormailites, low apgar scores, mechanical ventilation of 5 days or longer, or other syndromes known to included hearing loss.
Emaxhealth
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Although most of the ototoxic drugs have already been recognized by clinic doctors and pharmacologists.
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Simultaneous administration of several ototoxic agents or prolonged treatment with high dosages of an ototoxic medication should be avoided when possible.
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When examining the relationships between peak and trough vancomycin serum levels and the subsequent development of nephrotoxicity or ototoxicity, it is difficult to predict risk based on these data.
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The potential medicolegal implications of ototoxicity, therefore, have created a dilemma: we need to determine which topical antibiotic is safe and effective in treating patients with chronic discharge from their ears.
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For example, aquatic organisms that have assimilated UV-B absorbing polyaromatic hydrocarbons have shown phototoxic effects when exposed to UV-B radiation.
Climate change, interactive changes and stresses in the Arctic
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Most of the rare reports of ototoxicity or nephrotoxicity in patients receiving vancomycin are complicated by concomitant illness or drug use associated with such side effects.
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Infants at high risk for hearing loss are those with a family history of hereditary childhood sensorineural hearing loss, hyperbilirubinemia, ototoxic medications, bacterial meningitis, birth weight of less than 1500 grams (3.3 pounds), in-utero infections, craniofacial abnormailites, low apgar scores, mechanical ventilation of 5 days or longer, or other syndromes known to included hearing loss.
Emaxhealth
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This genetic disorder leads to an accumulation of protoporphyrin IX in the skin and an increased risk of incapacitating phototoxic reactions manifesting as pain and severe ulceration of the skin.
THE MEDICAL NEWS
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Sunlight falling on the dispersed oil may make the problem worse through a phenomenon known as phototoxicity.
Scientific American
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Also, some dermatologists believe that home phototherapy is inferior to hospital treatment and carries more risks, such as inaccurate dosimetry, phototoxicity, and unsupervised continuation of irradiation.
MedPageToday.com - medical news plus CME for physicians
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The aim of the study was to compare ototoxicity, tolerability, and efficacy of ACT with that of quinine and atovaquone / proguanil in the treatment of uncomplicated falciparum malaria.
BioMed Central - Latest articles
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Aspirin is also an ototoxic drug: it can damage the ear to the point of causing hearing loss.
Yahoo! News: Business - Opinion
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In contrast, tumors and ototoxic medications produce slowly progressive unilateral or bilateral lesions.
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Leading causes of acquired hearing loss include infectious diseases, especially meningitis and otitis media, trauma to the nervous system, damaging noise levels, and ototoxic drugs.
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The safety profile of the formulation is generally favorable, with no demonstrable ototoxicity, nephrotoxicity, bone marrow suppression, or cardiovascular adverse effects.
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If you are taking ototoxic antibiotics then this may be the reason that your ears are ringing.
EzineArticles
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Several other drugs used in CF care have nephrotoxic and ototoxic potential.
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The increase in volume of tissue (a phenomenon known as hypertrophy) is believed to be less prominent in ototoxically deafened cats due to the treatment.
News-Letter
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However, application to the skin is problematic because the photosensitizing properties of the benzophenone moiety may cause phototoxic effects when the treated skin region is exposed to UVA light.
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It is assumed that people with dark eyes also have more melanin in the inner ear than those with light eyes, and melanin causes the retention of ototoxic derivatives within the cochlea.
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However, irreversible ototoxicity associated with artemether / lumefantrine (AL) has been reported recently and suggested to be a serious limitation in the use of ACT.
BioMed Central - Latest articles
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Thekey of preventing acquired deafness was to prohibit the misapplication of ototoxic antibiotics.
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However, it is thought that patients with little to no drainage at the time of surgery who may be at highest risk for ototoxicity because of the lack of inflammation of the middle car mucosa to decrease the round window permeability.
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Objective To investigate the ototoxicity of a new chemical preparation salicylate gentamicin.
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some drugs are ototoxic