NOUN
- a mouse with a genetic defect that prevents them from growing hair and also prevents them from immunologically rejecting human cells and tissues; widely used in preclinical trials
How To Use nude mouse In A Sentence
- A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells. Nudity among animals
- The genetic basis of the nude mouse mutation is a disruption of the FOXN1 gene. Nudity among animals
- Results The NIH3T3 cells transformed with K12 gene formed colony in soft agar and induce tumorigenesis in nude mouse.