How To Use Nucleoside In A Sentence
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One particular pleasure of that period was the development of the methoxyl-trityl family of protecting groups for nucleoside-5'-hydroxyl groups (one synthesis of trimethoxytritanol erupted and left a large orange stain on the laboratory ceiling); this class of protecting group is still in use in modern automated syntheses of DNA and RNA fragments.
Michael Smith - Autobiography
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It is therefore noteworthy that nucleosides and nucleotides can generate singlet oxygen when directly excited by UV light and thus have the potential for self-sensitized oxidative degradation.
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The steady-state ITC method has been used to determine the enzyme kinetics parameters of several enzymes, including H. pylori urease, E. coli GroEL chaperonin, heparinase I, yeast hexokinase, HIV protease, pyruvate carboxylase, and dinucleoside polyphosphate hydrolase.
GEN News Highlights
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Purine salvage pathway allows interconversion of bases, nucleosides and nucleotides.
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Recommended name pyrimidine-deoxynucleoside 2'-dioxygenase Synonyms deoxyuridine
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The chemical and biological effects of UV radiation on purine and pyrimidine nucleosides and nucleotides have been the subject of many studies.
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Abacavir Sulfate Tablets are used in combination with other medications to control HIV infection and is included in the ARV class of drugs known as nucleoside reverse transcriptase inhibitors.
Mylan's Matrix Receives Tentative FDA Approval Under PEPFAR for Abacavir Sulfate Tablets, 60 mg - Yahoo! Finance
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The synthesis of nucleotides from the purine bases and purine nucleosides takes place in a series of steps known as the salvage pathways.
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I had to work out the determination of the independent specific activities of the sugars and bases which I did by treating the nucleosides with nucleoside phosphorylase and hypoxanthine to exchange for the base to be analyzed.
Irwin Rose - Autobiography
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The drug is included in a class of drugs known as nucleoside reverse transcriptase inhibitors, and the tablet is a preferred form because of its ease, accuracy and convenience of dosing, according to the company.
Mylan AIDS drug gets tentative FDA approval | Pittsburgh Business Times
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Recommended name pyrimidine-deoxynucleoside 2'-dioxygenase Synonyms deoxyuridine
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Clofarabine, a type of drug called a purine nucleoside antimetabolite, works by blocking the production and repair of DNA, the building blocks of genes.
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Didanosine works by reducing the growth of HIV. It belongs to a class of medications called nucleoside analogues.
DWS Pill Scribe
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- 1995: Two new classes of anti-HIV drugs, also targeting replication, are approved: protease inhibitors and non-nucleoside reverse transcriptase inhibitors.
ANC Daily News Briefing
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List of Abbreviations NDP nucleoside 5'-diphosphate NEM N-ethylmaleimide Neu neuraminic acid NMN nicotinamide mononucleotide NMP nucleoside 5'-monophosphate NTP nucleoside
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All three drugs are known as non-nucleoside reverse transcriptase inhibitor drugs, or NNRTIs.
ANC Daily News Briefing
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The invention discloses a seleno acylglycerol phospholipid compound containing tegafur and synthesis thereof, and relates to organic selenium and a nucleoside substance.
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In looking for a way to designate the ring face of a simple ring compound such as G6P or of the two rings of a nucleoside, or of fused ring compounds such as sterols, we realized that a universal method could be devised using the established rules for numbering the atoms of rings as contained in standard chemical handbooks15.
Irwin Rose - Autobiography
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No mutations were detected associated with resistance to multinucleoside or nucleotide reverse transcriptase inhibitors, such as Q151M or insertions at codon 69.
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When the acyclic adenosine analog was tested in the antiviral screen, it showed antiherpetic activity in vitro at about twice the concentration of ara-A The antiviral program now concentrated on the acyclic nucleoside analogs, with the syntheses conducted by Schaeffer and Beauchamp, the antiviral testing by Bauer and Collins, and the mechanisms of action, enzymology and in vivometabolism by my group (108,109).
Nobel Lecture The Purine Path To Chemotherapy
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Then why does no one call G proteins motors, despite the fact that they harness the energy from hydrolysis of a nucleoside triphosphate to cause a conformational change by the same mechanism seen in myosins and kinesins?
Analogy, How Scientifically Powerful is It?
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Nucleoside analogs such as cytarabine and gemcitabine are powerful anticancer agents, but a simple c ...
THE MEDICAL NEWS
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I had to work out the determination of the independent specific activities of the sugars and bases which I did by treating the nucleosides with nucleoside phosphorylase and hypoxanthine to exchange for the base to be analyzed.
Irwin Rose - Autobiography
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The nucleosides are better models for the bases in DNA and RNA because the sugar moiety eliminates tautomers that cannot occur in the polymers.
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The purine and pyrimidine bases in cells are linked to carbohydrate and in this form are termed, nucleosides.
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The combination therapy of one protease inhibitor and two nucleoside transcriptase inhibitors has markedly increased the number of CD4 cells and decreased the viral load of patients.
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This suggested that other enzymes might also recognize such a side chain as a pentose and that nucleoside analogs of this kind might have antimetabolite properties.
Nobel Lecture The Purine Path To Chemotherapy
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In an attempt to shed light on this matter, we have studied the intrinsic fluorescence properties of the purine and pyrimidine nucleosides dA, dG, dT, and dC in organic solvents in the presence of small amounts of water.
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Purine salvage pathway allows interconversion of bases, nucleosides and nucleotides.
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To study efficiency of nucleoside peptide nutrient on antioxidation function of rat by 3 dosage group.
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A white, odorless powder, C9H12N2O6, that is the nucleoside of uracil, important in carbohydrate metabolism, and used in biochemical experiments.
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Several nucleoside-based inhibitors of these viral enzymes, including that of the HIV virus, also typically show modest inhibition of telomere synthesis.
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Two of these, adenylate kinase and purine nucleoside phosphorylase, contain potential critical building blocks.
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Hepatic steatosis, most commonly associated with the nucleoside analogs, didanosine, stavudine and zalcitabine can lead to severe hepatotoxicity in HIV / HBV co-infected patients.
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It's a nucleoside reverse transcriptase inhibitor, or an NRTi, in AIDS speak.
Charles Karel Bouley: HIV Prevention Drug: Thanks, But No Thanks
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The disorders can be treated with uridine and/or cytidine, which leads to increased UMP production via the action of nucleoside kinases.