How To Use Nucleic acid In A Sentence
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Its addition in minute amounts to the nucleoprotein tumor fraction, was expected to suppress the formation of the fibrillar halo if nucleic acids rather that the protein were responsible for the nerve growth promoting effect elicited by this fraction.
Nobel Lecture The Nerve Growth Factor: Thirty-Five Years Later
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He is seeking a causal source for the sequence specificity found in nucleic acids and proteins.
Are Stereochemical Explanations Causally Sufficient?
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Unlike larger polypeptides and proteins, small nucleic acid duplexes and hairpins do not have a dense core to which this effect would apply.
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However, reactive oxygen species generated by UVA radiation, particularly singlet oxygen, can also damage nucleic acids.
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Ribonucleic acid (RNA) – the biomolecule which can do it all
The Nobel Prize in Chemistry 1989
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A virus is a small packet of infectious nucleic acid material surrounded by a protein coat.
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Nucleic acids were extracted from grains of wheat using a modification of the CTAB protocol as described by SALLARES et al. 1995.
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These genes are now known to be molecules of a substance called deoxyribonucleic acid and each of these molecules has a little code of information on it that permits it to manufacture duplicates of itself to be handed on for example, to one's children, and also to manufacture special molecules such as the molecules of proteins, in which each atom is put in its right place in this product molecule.
WN.com - Financial News
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A magnet then holds the beads/nucleic acids on the side of the tip while remaining material is ejected.
The Scientist
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We will show, I hope, fairly conclusively that there is little or no interconversion between the two types of nucleic acid synthesis in the cell.
On Handling the Data
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The three investigators found that a porous clay called montmorillonite, already known to encourage the linking of nucleic acids, also has an effect on fatty acids, the building blocks of cell membranes.
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Water, protein, fat, ribonucleic acid, carbohydrate and a little mineral substance, fragrant odor.
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The present invention proposes exonuclease III digesting double stranded nucleic acid molecule coated in microporous plate and containing special marker to detect transcription factor protein.
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Many Nobel Prizes have been awarded for the determination of the structure of biological macromolecules (proteins and nucleic acids).
The Nobel Prize in Chemistry: The Development of Modern Chemistry
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After purification, the isolated nucleic acids can be used for any downstream application.
The Scientist
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He also studied the orientation of purines and pyrimidines in tobacco mosaic virus and in nucleic acids, by measuring the ultraviolet dichroism of oriented specimens, and he studied, with the visible-light polarizing microscope, the arrangement of virus particles in crystals of TMV and measured dry mass in cells with interference microscopes.
Maurice Wilkins - Biography
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He has demonstrated the interconversion of a linear nucleic acid molecule to a ring-shaped one.
Physiology or Medicine 1969 - Press Release
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Because nucleic acids always carry a negative charge, separation of nucleic acids occurs strictly by molecular size.
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Helicases are protein motors that use the energy of NTP hydrolysis to dissociate the hydrogen bonding between the nucleic acid duplexes and also to disrupt other non-covalent interactions between complementary base pairs.
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Bradford, about the detachable pattern in nucleic acids: The detachable pattern is the genome.
A Minimal Genome
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'by truely living organisms and are either then ingested (much as a paramecium will' ingest 'strings of free-floating DNA) and by default should be considered to be' information data packets 'that have come to exist because they have evolutionary advantage to the organisms which are able to use the nucleic acid's data.
PhysOrg.com - latest science and technology news stories
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In support of the virino hypothesis is the existence of different strains of prions that cause differing patterns of disease and breed true; the existence of strains in pathogens is usually the result of changes in the nucleic acid sequence of the infectious agent.
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We do not really understand the origins of biological information, but I suspect there is a lot of inadvertency in those early events and in the choice of which particular nucleic acids and amino acids were employed when life began.
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Both strands can act as templates to produce a molecule called ribonucleic acid.
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One of the technologies that has enabled this profile are the bicyclic nucleic acid chemistries such as locked nucleic acids LNAs.
Forbes.com: News
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For substances containing allyl or allylic side chains a direct mechanism of action involving an allylic cation which then reacts with nucleophilic centers of nucleic acid bases has been discussed in the literature.
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Next Big Future
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Bradford, you're the one who seems to be supporting the notion that there is CSI in nucleic acids.
A Minimal Genome
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Nucleic acids are also polymers, composed of repeating units called nucleotides.
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What we found was a far bigger revelation than we were expecting: it was a new form of cellular self-control based on one of the oldest types of molecule around— ribonucleic acid, or RNA.
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Peptide nucleic acids ( PNAs ) constitute an attractive new class of probes, recently introduced in cytogenetics.
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We select this level of quasi-rigidity at 0.23 following a previous investigation of the dynamics of double helical nucleic acid oligomers.
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He called this compound nuclein; today we call it nucleic acid.
Nobel Prize in Physiology or Medicine 1968 - Presentation Speech
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The riboswitch Block's team studied grabbed onto a molecule called adenine, the nucleic acid dubbed "A.
Biosingularity
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Summary : The candy chain a chain after third life following protein, nucleic acid.
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Nevertheless, the most optimal method for extracting nucleic acid must also be determined for each specimen type.
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High resolution is a necessity when performing nucleic acid analysis.
The Scientist
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Organotherapy has a direct effect on stimulating the function of the organ by enhancing the selection of enzymes and specific nucleic acids lacking in the organ.
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The C5 atom of cytidine bears a substantially larger negative charge than many nitrogen atoms in popular nucleic acid force fields.
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Clearly, the binding to DNA effectively shields the chromophores from quenching by nitromethane, consistent with an intimate association of the compounds with the nucleic acid.
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A nitrogenous molecule, either a PYRIMIDINE or a PURINE, that combines with a pentose sugar and phosphoric acid to form a nucleotide, the fundamental unit of nucleic acids.
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A chronometer is hidden within all words, and in each length of nucleic acid.
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The early chapters give a basic knowledge of nucleic acid metabolism and chemistry, with an outline of elementary genetics.
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The functions of these non-coding nucleic acid sequences are only partly understood.
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In other words, DNA is a molecule called deoxyribonucleic acid that gives life its biological instructions.
Yahoo! News: Business - Opinion
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It translates genetic information from messenger ribonucleic acid and makes protein accordingly.
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I typed it out as I was thinking about how some major classes of biomolecules - protein, carbohydrate, lipid, and nucleic acid - are perceived.
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Monera morphology mutagen mutations natural selection neurotransmitter nitrogen fixing nitrogenous wastes nucleic acids nucleotides nucleus omnivore opposable thumb order organ organelles organic compounds organic molecules
21. Life Sciences
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The primary categories for natural polymers include polysaccharides, proteins, nucleic acids, and polyisoprenes.
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Some of these complexes form immensely complicated sequences of nucleic acids which begin to replicate themselves.
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The fluorescence enhancement upon binding nucleic acid is also important.
The Scientist
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Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication.
SuperCooperators
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However, each set of to occupy those realms by multiple complete physical form into an mand for the regeneration of the bodies can be made to carry a dif - physical embodiments all connected energy form which can be pro - Adamic race and the preparation of ferent nucleic acid template on with one mind. jected to a vehicle or a n environ - the Christ people for n e w worlds which proteins of specific 15 Thus, one mind will transmit ment in the lower heavens where it of creation, a change in biological stereoisomeric forms have been to many bodies as one genetic code can be remodulated into the same life could not now evolve on Earth, synthesized. is used a s the master code for physical form.
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These basophil granules have been named chromatin or basichromatin and owe their staining properties to the presence of nucleic acid.
I. Embryology. 1. The Animal Cell
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RB has modest affinity for nucleic acid and little affinity for albumin or either phospholipid.
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A multidisciplinary international team demonstrated through botanical examination, phytochemical investigation, and genetic deoxyribonucleic acid analysis by polymerase chain reaction that this material contained tetrahydrocannabinol, the psychoactive component of cannabis, its oxidative degradation product, cannabinol, other metabolites, and its synthetic enzyme, tetrahydrocannabinolic acid synthase, as well as a novel genetic variant with two single nucleotide polymorphisms.
2,700-year-old marijuana stash found
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Unlike larger polypeptides and proteins, small nucleic acid duplexes and hairpins do not have a dense core to which this effect would apply.
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The present invention proposes exonuclease III digesting double stranded nucleic acid molecule coated in microporous plate and containing special marker to detect transcription factor protein.
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Such " ribozymes " are often used to catalyze reactions involving deoxyribonucleic acid or RNA.
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NMR spectroscopy, which provides atomic resolution images of biological molecules such as proteins and nucleic acids, showed these aromatic rings were made of lignin derivatives that are abundant in rice soils.
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This genetic material, also known as DNA deoxyribonucleic acid, is found in the genes, which together form the chromosomes—small threads in the nucleus of the cell.
Modern Science in the Bible
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The statement that functional polynucleotides (nucleic acids) can spontaneously form is equivalent to the statement that the ink and paper of a printed page can organize themselves into a meaningful text.
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Genetic information is programmed like a chemical code in deoxyribonucleic acid, better known by its abbreviated name of DNA.
The Nobel Prize in Chemistry 1989 - Presentation Speech
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Components of the primary genetic material in our cells, called deoxyribose nucleic acid
The World's Healthiest Foods
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Most viruses in the ocean consist of nucleic acids surrounded by a protein coat (called a capsid).
Marine viruses
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People assumed nucleic acids carried genetic information and proteins catalyzed reactions or signaled cellular events.
The Scientist
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Millett IS, Herschlag D, Doniach S (2005) Probing counterion modulated repulsion and attraction between nucleic acid duplexes in solution.
PLoS ONE Alerts: New Articles
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Researchers have used this approach to identify protease and kinase substrates, protein: protein interactions, and protein: nucleic acid interactions.
The Scientist
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ribonucleic acid is the genetic material of some viruses
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Reverse transcriptase, polymerase chain reaction, nucleic acid probe test---the whole nine yards.
MINUTES TO BURN
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The expression is used to analyze experimental data for the stretching of various different types of biopolymers: polypeptides, polysaccharides, and nucleic acids.
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However, as mammalian cells will not readily take up naked nucleic acids, the RNAs have to be complexed with agents such as cationic lipids to allow them to enter the cells.
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If this mass of nuclei is brought into contact with dilute acids the greater part of the protein is dissolved while the nucleic acid is left.
Albrecht Kossel - Nobel Lecture
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Enzymes that act on substrates such as polypeptides, nucleic acids, oligosaccharides, or lipid membranes often interact with more than one substrate molecule.
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Not always necessarily at the same time, but at least to be able to look at protein kinase activity, redox state, gene transcription, protein degradation, localization of DNAs and RNAs by slightly more indirect means, which if you use GFP and RFP to label a protein that in turn binds specifically to your favourite nucleic acid, and the list goes on and on.
Roger Y. Tsien - Interview
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Enzymes that act on substrates such as polypeptides, nucleic acids, oligosaccharides, or lipid membranes often interact with more than one substrate molecule.
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Material was spun at 6000 rpm for 1 min to pellet nucleic acid, and supernatant was removed to a clean tube.
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The interaction between clomifene citrate(CC) and deoxyribonucleic acid (DNA) was studied by fluorescence spectroscopy using ethidium bromide (EB) as a fluorescence probe.
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This system labels nucleic acids, antibodies, proteins, and peptides with chemiluminescent acridinium esters.
The Scientist
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Any of several basic compounds derived from or structurally related to pyrimidine, especially the nucleic acid constituents uracil, cytosine, and thymine.
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However, the lock is always a very complicated molecule of high molecular weight, a protein or a nucleic acid.
The Nobel Prize in Chemistry 1987 - Presentation Speech
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Enzyme immunoassays for detecting chlamydial antigen and direct nucleic acid probe assays are the most widely used tests and can evaluate large numbers of samples.
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Let us remember that they are concerned with a DNA endonuclease, so I had some experience dealing with an enzyme that cut nucleic acids.
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The opening sentence of his paper, written with his colleague Jim Watson and published in Nature that year, put it more modestly: "We wish to suggest a structure for the salt of deoxyribose nucleic acid.
The Twentieth-Century Darwin
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The polymerase chain reaction assay, branched DNA assay and nucleic acid sequence-based amplification assay quantitate human immunodeficiency virus RNA levels.
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The calculations of Sponar suggest the nonplanarity of amino groups that are bound to aromatic systems such as in aniline or in the nucleic acid bases.
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The binding reaction of Bismarck Brown R and nucleic acid was studied by the spectrophotometric method.
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We have modeled the closing kinetics and in so doing have obtained stacking enthalpies and entropies for single-stranded nucleic acids.
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Deoxyribonucleic acid samples were obtained from buccal swabs; a cytology brush was used.
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The most widely used method for separation of nucleic acids is precipitation with ethanol or other organic solvents.
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Various diagnostic techniques such as improved culture techniques, serodiagnosis, and nucleic acid amplification have been developed and evaluated to improve diagnosis of childhood tuberculosis.
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The research of ribonucleic acid structures and functions and its applications has always been one of the significant field of biology .
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It's those messages stored in nucleic acids and the need to express them which leads me to believe there is a disconnect between prebiotic conditions and the actual causal genesis of the former.
Another Look
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Hydrogen bonding also plays an important role in determining the three-dimensional structures adopted by proteins and nucleic acids.
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Helicases are protein motors that use the energy of NTP hydrolysis to dissociate the hydrogen bonding between the nucleic acid duplexes and also to disrupt other non-covalent interactions between complementary base pairs.
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Direct labeling involves the introduction of a covalently linked fluorophore in the nucleic acid sequence.
The Scientist
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The beads are washed, and purified nucleic acids are released into a small volume.
The Scientist
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DNA and RNA are both nucleic acids.
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It was hypothesized that the water used to resuspend the nucleic acid was not at the proper pH.
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In the virino model, the host protein protects the scrapie agent nucleic acid from degradation and prevents the host raising an immune response, since the protein/nucleic acid complex is seen as ‘self’.
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Carbohydrates are made of simple sugars, proteins are made up of 20 amino acids, and nucleic acids are compose of oxy- and deoxy- nucleic sugars and 5 base pairs.
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ADA which has important relationships with the immune system of the body, is a kind of catabolic enzymes of nucleic acid. ADA can specifically catalyze adenosine to generate irreversible deamination.
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units of nucleic acids
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Art, CSI is found in nucleic acids, not activities.
A Minimal Genome
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A competing theory points to virinos (mini viruses), that are using particularly tough protein ‘shells’ to contain their small amount of nucleic acid.
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Phenolic compounds in plants are notorious for their detrimental effects in both nucleic acid and protein research.
The Scientist
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This advanced nucleic acid amplification test is rapidly gaining importance in diagnostic microbiology.
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Singer continued her research in nucleic acids and was intensely involved in developing related policy.
Maxine Singer: Biochemist
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The Human Genome Project has promoted the development of nucleic acid sequence analysis technology.
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Church, “The cleavage site of the restriction endonuclease Ava II,” Nucleic Acids Research 5 1978, 2313–2319.
The $1,000 Genome
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The early chapters give a basic knowledge of nucleic acid metabolism and chemistry, with an outline of elementary genetics.
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Transport of polyelectrolytes, in particular of nucleic acid fragments, through proteinaceous pores in membranes has also been reported.
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Plants then synthesize antimicrobial substances, including the protein chitinase, which degrades the cell walls of fungi, and enzymes called nucleases, which break apart the ribonucleic acid of viruses.
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In contrast to the colinearity hypothesis that a continuous nucleic acid sequence generated an amino acid chain, it became apparent that stretches of DNA were often split between coding regions (exons) and non-coding regions (introns).
Molecular Biology
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The early chapters give a basic knowledge of nucleic acid metabolism and chemistry, with an outline of elementary genetics.
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ADA which has important relationships with the immune system of the body, is a kind of catabolic enzymes of nucleic acid. ADA can specifically catalyze adenosine to generate irreversible deamination.
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Most people know that the instructions for producing a living organism are encoded in the sequence of four bases (A, T, G and C) in a long molecule called deoxyribonucleic acid (DNA).
Scientific Blogging
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Therefore, as the tissue is processed as a mass, a nucleic acid-based approach usually involves contamination by nonmalignant and nonviable cancer cells.
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Quality control was performed to ensure the tissue specimens contained sufficient quantity of nucleic acids for amplification testing.
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RNA (ribonucleic acid) in living cells is not only a molecule of heredity but also can function as a biocatalyst.
Press Release: The 1989 Nobel Prize in Chemistry
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The unmodified biopolymers may be nucleic acids, polypeptides, proteins, carbohydrates, lipids and analogues thereof.
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RNA – ribonucleic acid – is a copy of the DNA instructions that serves as a messenger to direct protein synthesis, which is then destroyed after it has fulfilled its function.
Exploring the New RNA World
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Reverse transcriptase, polymerase chain reaction, nucleic acid probe test---the whole nine yards.
MINUTES TO BURN
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In the first, DNA is spotted onto a glass slide; in the second, oligonucleotides of 15-30 nucleic acid base pairs are synthesised on to a silica slide by a process known as photolithography.
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With the advanced magnetic isolation method, the instrument can automatically isolate high purity nucleic acid from various samples, such as blood, tissue and cells.
