How To Use Norepinephrine In A Sentence
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Recent studies have revealed a correlation between prognosis in heart failure and plasma levels of such neurohormones as endothelin, norepinephrine and renin, among others.
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It is called GABA gamma-aminobutyric acid and it calms the brain from too much of the neurotransmitters epinephrine and norepinephrine.
The UltraMind Solution
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He then went on to study the release of norepinephrine from the adrenergic neurons in the ear artery by cholinergic agonists acting on prejunctional nicotinic receptors.
Robert F. Furchgott - Autobiography
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This results in rebound of the previously suppressed stimulatory transmitters (serotonin, norepinephrine and dopamine).
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Norepinephrine and serotonin may be excitatory or inhibitory, but they are functionally inhibitory on pain transmission; glutamate is the other important excitatory neurotransmitter.
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This diurnal variation in melatonin synthesis is brought about by norepinephrine secreted by the postganglionic sympathetic nerves that innervate the pineal gland.
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And the amino acid phenylalanine can be very helpful in boosting the other energy-giving, motivating, and focusing neurotransmitter norepinephrine.
The UltraMind Solution
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The postsynaptic receptors become supersensitive to neurotransmitter effects and may be related to an increase in the number of alpha and beta receptors. 4 This may occur in compensation for chronic cocaine use when norepinephrine becomes depleted. 4
Cocaine Toxicity
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It is advisable to use a direct-acting alpha-adrenergic agonist, such as norepinephrine, because their actions are not dependent upon the release of intracellular amines, the metabolism and availability of which are altered by MAO-I's.
Monamine Oxidase Inhibitors
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The theory behind standard antidepression medication is that the disease is caused by low levels of key brain chemicals like serotonin, dopamine, and norepinephrine, and thus by manipulating those imbalanced neurotransmitters, a patient's depression will be reversed or at least alleviated.
Dr. Larry Dossey: The Mythology Of Science-Based Medicine
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Its close cousins are the stimulating and energy-giving neurotransmitters epinephrine and norepinephrine.
The UltraMind Solution
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The printed sensors can be incorporated into logic-based biocomputing systems that will monitor biomarkers such as lactate, oxygen, norepinephrine and glucose.
Gizmag Emerging Technology Magazine
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In writing the 1955 review on the "Pharmacology of vascular smooth muscle," I had become very interested in the mechanisms by which sympathetic postganglionic denervation and certain drugs like cocaine markedly potentiate the response of effector organs to epinephrine and norepinephrine, yet markedly reduce the response to the sympathomimetic tyramine.
Robert F. Furchgott - Autobiography
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Locally it blocks the initiation and propagation of nerve impulses along an axon by interference with sodium permeability during depolarization. 3,11 Centrally it blocks the presynaptic reuptake of norepinephrine and dopamine.
Cocaine Toxicity
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It inhibits serotonin, norepinephrine, and dopamine reuptake.
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Norepinephrine is converted to epinephrine by an enzyme, N-methyltransferase, which is present almost exclusively in the adrenal medulla.
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My studies in graduate school involved developing a better understanding of why and how neurons of the sympathetic nervous system innervate the heart and produce and release norepinephrine.
Louis J. Ignarro - Autobiography
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Due to concerns about potential adverse vasoconstrictive effects on regional vascular beds, such as the liver and the kidney, norepinephrine traditionally had either not been used or had been reserved as a last resort in a moribund patient, with predictably poor results.
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In the brain, high levels of the catecholamines dopamine and norepinephrine are released in the PFC during stress exposure, even during relatively mild psychological stress.
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I geographically triassic what all the steinman is compulsorily on the bulge dissent norepinephrine so that i can canonization the shrubbery and tirolean. has to spear at its specifically fizzing, appropriately prophylactic haplotype, and stambul apogamy they jejunostomy to coot faker in mollification to do it.
Rational Review
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When you're under stress your adrenal glands produce the hormones cortisol, norepinephrine, and adrenaline.
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The addition of norepinephrine, epinephrine, dopamine, and dopa to the cultures of E. coli resulted in increased growth when compared to non-catecholamine-supplemented control cultures.
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Intravenous infusions of norepinephrine and phenylephrine were started to produce peripheral vasoconstriction and increase blood pressure.
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For example, damage to the central amygdaloid nucleus reduces activation of NTS and PVN neurons following IL - 1beta injections and attenuates stress-induced norepinephrine release in the PVN.
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Specific hormones that belong to this category are epinephrine and norepinephrine.
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All of the molecules in a given vesicle are identical; that is, a vesicle will contain only norepinephrine molecules or only GABA molecules.
Alcohol and The Addictive Brain
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I'm a catecholamine man myself: it's norepinephrine which does it -- that's a breakdown of tyrosine.
THE PRESIDENT'S CHILD
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Another potential clue regarding the pathophysiology of SCM is that patients with tumors that secrete epinephrine and norepinephrine (collectively referred to as catecholamines) can sometimes present with profound heart dysfunction as well.
MND: Your Daily Dose of Counter-Theory
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We found that catecholamine effects on adenylyl cyclase activation in both heart and liver preparations were, indeed, due to beta adrenergic effects as shown by the relative potencies of l-isoproterenol, l-epinephrine and l-norepinephrine with inhibition by dichloroisoproterenol and failure of alpha blockers and agonists to have effects.
Ferid Murad - Autobiography
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Phenylpropanolamine, a racemic mixture of norephedrine esters, causes a release of norepinephrine throughout the body and stimulates hypothalamic adrenoreceptors to reduce appetite.
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Serotonin is a vasoconstrictor and uses agonists, such as ADP, epinephrine, and norepinephrine, to promote platelet aggregation.
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In one paper, with the running page heading of "the cocaine paradox," we presented evidence that in aortic strips of rabbit and isolated electrically-driven atria from guinea pig and cat, cocaine potentiated responses to norepinephrine and inhibited those to tyramine by blocking one and the same site on adrenergic nerve terminals.
Robert F. Furchgott - Autobiography
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Chronic stress raises the level of the excitatory hormones, including norepinephrine and cortisol, which can wear your body down and lead to disease.
Forever Young
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Aim:To observe the effects of atenolol on plasma levels of norepinephrine and epinephrine in the patients with hypertension.
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Norepinephrine and serotonin are involved in the loss of muscle tone during REM sleep.
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Cocaine acts by inhibiting norepinephrine reuptake in peripheral sympathetic nerve terminals as well as stimulating central sympathetic outflow.
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Within the adrenal medulla dopamine is converted to norepinephrine and epinephrine.
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The messenger molecules tell those cells: `Hey, give our friend here a shot of dopamine or norepinephrine.
BLACK EAGLES
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I'm a catecholamine man myself: it's norepinephrine which does it -- that's a breakdown of tyrosine.
THE PRESIDENT'S CHILD
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Norepinephrine is a potent vasoconstrictor synthesized from tyrosine in the presynaptic neuron.
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Seeing that it’s involved in inactivation/metabolism of norepinephrine and dopamine (neurotransmitters), this may be similar in effect to reuptake inhibitors or catecholamine agonists ... you know, like amphetamines ....
The Volokh Conspiracy » Some Scientists’ Openness to the Possibility of Genetic Differences in Mental Traits Among Racial and Ethnic Groups
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Auspex Pharmaceuticals, a developer of next-generation medicines with improved safety and performance through the targeted deuteration of clinically validated drugs, today announced positive results from its Phase 1 clinical trial evaluating SD-254, a Selective Serotinin-Norepinephrine Reuptake Inhibitor (SNRI).
Medlogs - Recent stories
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Ondansetron, which indirectly blocks an adrenaline-like brain hormone called norepinephrine, appears to have fewer side effects than Inderal.
DROWNING ON DRY LAND
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Other hormones that influence blood sugar levels are cortisol, growth hormone and catecholamines (epinephrine and norepinephrine).
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Eventually sympathin was found to be a molecule named norepinephrine (also called noradrenalin), which is very similar in structure to epinephrine (or adrenalin), discussed toward the end of Chapter 2 (see pp. 40-43).
The Human Brain
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I'm a catecholamine man myself: it's norepinephrine which does it -- that's a breakdown of tyrosine.
THE PRESIDENT'S CHILD
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In this study, abrupt drug withdrawal reinduced norepinephrine dependency in 30% of patients previously weaned from vasopressors.
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I'm a catecholamine man myself: it's norepinephrine which does it -- that's a breakdown of tyrosine.
THE PRESIDENT'S CHILD
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The stimulants promote the release of dopamine and norepinephrine from presynaptic neurons into the synaptic cleft but then block reuptake by these same neurons.
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This adrenaline rush is an effect caused by the adrenal glands in the body manufacturing epinephrine, cortisol, and norepinephrine.
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It is advisable to use a direct-acting alpha-adrenergic agonist, such as norepinephrine, because their actions are not dependent upon the release of intracellular amines, the metabolism and availability of which are altered by MAO-I's.
Monamine Oxidase Inhibitors
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This diurnal variation in melatonin synthesis is brought about by norepinephrine secreted by the postganglionic sympathetic nerves that innervate the pineal gland.
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Opiates also inhibit the production of a chemical messenger called norepinephrine, which is thought to enhance fear signals in the brain.
The Seattle Times
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It inhibits serotonin, norepinephrine, and dopamine reuptake.
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These hormones include adrenaline, norepinephrine, aldosterone and corticosteroids (cortisone).
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For example, breathing in quick abdominal breaths—the Breath of Fire—stimulates the splanchnic nerves in the abdominal cavity, and potentiates release of stimulating epinephrine and norepinephrine.
Meditation as Medicine
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• Stimulation of the splanchnic nerves, causing increased output of epinephrine and norepinephrine
Meditation as Medicine
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If a pressor agent must be used, a direct-acting alpha-adrenergic agonist such as norepinephrine is preferable because it acts without releasing intracellular amines.
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Over time, these over-excited receptors become desensitized to the effects of norepinephrine, largely due to the effects of a second molecule, beta-adrenergic receptor kinase.
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As a natural response to a diseased heart, the body releases the hormone norepinephrine, causing the heart to beat up to five times faster than normal.
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The second mechanism of TCA cardiotoxicity involves the blockade of norepinephrine uptake at the adrenergic presynaptic endings.
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According to a study conducted by Alec Roy, M.D. formerly at the National Institute on Alcohol Abuse and Alcoholism, norepinephrine is secreted under stress, arousal, or thrill, so pathological gamblers gamble to make up for their underdosage.
New morning ritual
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This result is due to several factors: a direct release of norepinephrine from storage vesicles, the blockage of reuptake of norepinephrine once it has been released into the synaptic cleft and a decrease in norepinephrine metabolism due to inability of MAO to break down norepinephrine.
Monamine Oxidase Inhibitors
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Thus, sympatholytics interfere with the part of the nervous system that uses norepinephrine to raise blood pressure.
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Drugs that enhance the effectiveness of norepinephrine and serotonin are commonly used as antidepressants.
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In addition to their effects as neurotransmitters, norepinephrine and epinephrine can influence the rate of metabolism.
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The phenylalanine from the dipeptide component of the aspartame molecule, is a major precursor in the norepinephrine-dopamine synthetic pathway.
Pennsylvania Psychiatrist and Aspartame Expert Endorses Hawaii and New Mexico Aspartame Legislation
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Thus, large doses of the drug may be required in some patients with septic shock, possibly due to α-receptor down-regulation in sepsis. 111 Cardiovascular Effects Norepinephrine therapy usually causes a clinically significant increase in MAP attributable to its vasoconstrictive effects, with little change in HR or cardiac output, leading to increased systemic vascular resistance.
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We showed that the positive inotropic effects of norepinephrine and strophanthin-K were correlated with an increase in rate of exchange of calcium in an intracellular pool associated with the contractile process and that the negative inotropic effects of acetylcholine and adenosine were correlated with a decrease in rate of exchange in that pool.
Robert F. Furchgott - Autobiography
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Some scientists believe that the combination of the norepinephrine and endorphins help us to learn quickly and permanently.
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While some antidepressants actually increase weight, at least one—called bupropion (Wellbutrin)—has been shown to be effective for weight loss by influencing levels of norepinephrine (the fight-or-flight neurochemical), as well as increasing the pleasure-seeking dopamine.
You: On a Diet
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When blood pressure could not be maintained with a dose of 20 µg per kilogram of body weight per minute for dopamine or a dose of 0.19 µg per kilogram per minute for norepinephrine, open-label norepinephrine, epinephrine, or vasopressin could be added.
Medlogs - Recent stories
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In that same year, W. B. Cannon found an accelerator substance released by the sympathetic nerves, and called it sympathin.5 It was later shown by U.S. von Euler to be a combination of epinephrine and a similar substance called norepinephrine.6 Cannon went on to characterize the function of the sympathetic (norepinephrine) and parasympathetic (acetylcholine) divisions of the autonomic nervous system.
Alcohol and The Addictive Brain
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The conceptual basis of progressive left ventricular dysfunction has now turned to neurohormones such as norepinephrine, angiotensin and aldosterone.
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Low dose norepinephrine in patients with septic shock and oliguria: effects on afterload, urine flow, and oxygen transport.
Recently Uploaded Slideshows
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Serum levels of atrial natriuretic peptide, brain natriuretic peptide, norepinephrine and other neurohormones are elevated in patients with heart failure.
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Tofranil is an older medication, known as a tricyclic antidepressant, which works by making more of the neurotransmitters serotonin and norepinephrine available.
Medlogs - Recent stories
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MAOI drugs like iproniazid, on the other hand, countered the reserpine effect and raised levels of norepinephrine.
MANUFACTURING DEPRESSION
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I geographically triassic what all the steinman is compulsorily on the bulge dissent norepinephrine so that i can canonization the shrubbery and tirolean. has to spear at its specifically fizzing, appropriately prophylactic haplotype, and stambul apogamy they jejunostomy to coot faker in mollification to do it.
Rational Review
