How To Use Neuronal In A Sentence
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Our interneuronal connections in our brain, for example, process information at chemical signaling speeds of a few hundred feet per second, compared to a billion feet per second for electronics - electronics is a million times faster.
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Conclusion: Both spinal and supraspinal neuronal Phosphoinositide 3-kinase(PI3K) pathway played important role in morphine dependent and naloxone-precipitated withdrawal response in mice.
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L1-CAM, together with other members of the L1 subfamily, is critical for several early development processes like axon outgrowth, fasciculation, neuronal migration and survival
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Astrocytes, previously thought to be unimportant in neuronal transmission, have recently been implicated in long-term modulation of neuronal synapses.
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Our data cofirm previous evidences, that long-term neuronal consequences of high-dose cholinergic activation are not necessarily derived from prolonged seizure activation (as seen in SE)
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Now there are new tools that let us see the interneuronal connections and their signaling, in vivo, and in real-time.
2005/04 - 2005/05
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Many theories propose that listening to and interpreting music with complex patterns activates the neuronal pathways in the hippocampus, which can lead to an increased efficacy of the neurons.
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A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis
Innovations-report
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Conclusion: Maternal folate deficiency can change the ultrastructure of fetal rat lobus frontalis. It may lead to abnormality of neuronal function and disturb fetal brain development.
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Other in vitro studies showed that the same cannabinoid could protect against neuronal death in response to hypoxia and glucose deprivation in cell culture conditions, but this effect was not mediated by CBI or CB2 receptors.
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Nevertheless, the mechanism of neuronal cell cycle activation remains unclear.
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These modulate the neuronal circuits that are thought to be dysfunctional in such disorders.
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Consider the physiologist's intuition that an increased neuronal firing frequency explains increased intensity of experience.
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Broadly expressed cell markers, such as the neuronal nuclei antigen NeuN, the glial fibrillary acidic protein (GFAP), myelin proteolipid protein (PLP) and the fractalkine receptor CX3CR1 (which identify neurons, astrocytes, oligodendrocytes and microglia, respectively), are commonly used in immunohistochemical analysis of brain development or disease.
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Non-drugged rats that were placed in the complex cages had spiny neurons with increased dendritic branching, reflecting new neuronal development.
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This Institute brings together for the first time the basic neurosciences with psychiatry and neurology to investigate the fundamental neuronal basis of mental illness.
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Another suggested cause is calcium-induced neuronal death which could implicate disruption of cytoskeletal microtubules inside neurons as the precipitating factor.
Deepak Chopra: End-of-Life Brain Activity - A Sign of the Soul?
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These measurements correlate with neuronal cell count and show a relative reduction of neurons in the epileptogenic hippocampus.
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Maybe in another 65 million years, give or take, cranial capacity will come to equilibrate with neuronal/mental capability.
Matthew Yglesias » Arctic Seabed Methane Stores Destabilizing
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Values are mean percentage±sem of the total number of neuronal somata.
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Neuronal GSX expression, as reported from several hydrozoan and anthozoan species, is clearly more significant.
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They are long lived, grow rapidly in culture, and, with careful prompting in the laboratory, have the potential to induce the formation of specialized dentin, bone, and neuronal cells.
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Accordingly, in pre-empting neuronal glucose utiliztion by the neuron, ketone bodies may compromise neuronal energetic efficiency and, together with both endogenously generated and diffusible ROS exported by the fatty acid-oxidizing astrocyte, promote cell injury.
Metabolism and ketosis | The Blog of Michael R. Eades, M.D.
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The C8-B4 clone was created in 1996, and the neuronal cells grow adherently in culture.
Undefined
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Now he's looking to crowdfund his next research project, on the neuronal effects of amphetamines.
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RNA cannot immediately play a role in neuronal functions; it might however, be important for long-term neuronal processes.
Eric R. Kandel - Autobiography
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Gouras also developed many of the non-invasive methods used to assess neuronal function in mouse visual system, such as electroretinography, which measures the retina's response to light.
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Dissemination occurs in immunosuppressed individuals via hematogenous or direct neuronal extension.
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TC-5214 blocks these brain receptors, which are called neuronal nicotinic receptors.
AstraZeneca Dealt Setback on Antidepressant
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The idea is the turn up the volume of neuronal signals that use acetylcholine as a transmitter molecule, by inhibiting the enzyme that would break it down and sweep it out of the synapse.
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Hanson has shown that amphetamines increase the concentration of catecholamines in the synaptic cleft by stimulating their release from the interneuronal storage vesicles.
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At the present time we can only speculate about the implications of such ‘experience-dependent shaping of neuronal circuits’ for facilitating the deep psychobiology of therapeutic hypnosis.
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Temburni, MK, et al. Receptor Targeting and Heterogeneity at interneuronal nicotinic cholinergic synapses in vivo.
T.S. Wiley: Estrogen Dilemma: There Is No Dilemma When You Know the Details
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My understanding is represented in vast patterns of neurotransmitter strengths, synaptic clefts, and interneuronal connections.
'I Married a Computer': An Exchange
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Neuronal Transmission, Cellular Excitability, and Calcium Signaling The many markers involved in the assembly, function and / or regulation of neurotransmitter receptors, included several related to peptidergic, aminergic, and cholinergic signaling, and suggested that HVC is a major target of neuromodulation by these pathways (
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More information: "A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis", Published: Aug. 17, 2010, in
PhysOrg.com - latest science and technology news stories
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The basic types of changes due to toxins can be divided into three categories - sensory, motor, and interneuronal - depending on the type of damage sustained.
Neurotoxicity
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Xu YA, Gada H, Guttmann RP, Siman R (2003) Cross-talk between calpain and caspase proteolytic systems during neuronal apoptosis.
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In epilepsy sufferers, the brain is hyperexcitable, meaning that when stimulated there is a much bigger increase in neuronal firing than in a normal brain.
Times, Sunday Times
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Now there are new tools that let us see the interneuronal connections and their signaling, _in vivo, _ and in real-time.
Asimov's Science Fiction
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Microinjection of bicuculline in the ventrolateral PAG led to a decrease in the neuronal responses to heat.
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Distinct subpopulations of astrocytes might differently contribute to modulate neuronal hyperactivity in the epileptogenic region, possibly by releasing in addition to glutamate, ATP, and other neuroactive signals, e.g.,
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Therefore, the homology of entomostracan and malacostracan neuronal stem cells remains uncertain.
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But because hypoglossal motoneurons and motor axons project to any one of the eight tongue muscles, it is unclear to which of these muscles the motoneuronal activities corresponded.
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Instead, the brain showed neuronal loss, gliosis, and glial cytoplasmic inclusions in the striatum and substantia nigra, leading to the diagnosis of striatonigral degeneration.
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Another strategy was to create "electrochromic dyes" with large changes in dipole moment between ground and excited state, so that a change in neuronal membrane potential could shift the peak wavelengths of absorbance or fluorescence4.
Roger Y. Tsien - Autobiography
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At the same time, and by the very same token, the enlarged forebrain permits increased neuronal processing of olfactory information, so the tight chemical coupling between olfaction and endocrine release is no longer so necessary.
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Dissemination occurs in immunosuppressed individuals via hematogenous or direct neuronal extension.
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Our results uncover a protein involved in neuronal homeostasis, identify a family of candidate genes to be screened in patients with Kufs 'disease, and suggest that a deficiency in sulfatase is part of the NCL pathogenesis.
Innovations-report
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Ed, back up for a minute - are you saying that as a result of the literacy training, the grey matter in the adult sample increased (you wrote: "had more grey matter in five regions towards the back of their brains") as in somehow added more neuronal cell bodies, neuropil, etc.,
Literacy News – 64th Edition « News « Literacy News
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The hyposensitivity in the gut was accompanied by a 46% increase in the somatic referred pain areas indicating central neuronal changes.
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Neuropathic itch occurs with any disease along the afferent neuronal pathway.
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They are long lived, grow rapidly in culture, and, with careful prompting in the laboratory, have the potential to induce the formation of specialized dentin, bone, and neuronal cells.
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The brain showed extensive neuronal loss and severe astrogliosis in the striatum and substantia nigra.
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Accordingly, in pre-empting neuronal glucose utiliztion by the neuron, ketone bodies may compromise neuronal energetic efficiency and, together with both endogenously generated and diffusible ROS exported by the fatty acid-oxidizing astrocyte, promote cell injury.
Metabolism and ketosis | The Blog of Michael R. Eades, M.D.
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To explore ER fragmentation further, we transfected hippocampal cultures to express a fluorescent protein targeted to the ER (EGFP-ER or DsRed2-ER (RedER) where the fluorescent protein is flanked by an ER-targeting sequence and a KDEL ER retention signal previously shown to label neuronal ER
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This primary pathology includes a range of inflammatory disorders as well as neuronal loss along with dendritic damage and synaptic loss.
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Torres-Aleman, I, et al. Estradiol promotes cell shape changes and glial fibrillary acidic protein redistribution in hypothalamic astrocytes in vitro: a neuronal-mediated effect.
T.S. Wiley: Estrogen Dilemma: There Is No Dilemma When You Know the Details
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Ecstasy alters neuronal function in a brain structure called the hippocampus, which helps create short-term memory.
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The inhibitory effect of the GABA/benzodiazepine complex on neuronal discharge produces sedation, anticonvulsant activity, anxiolysis and striated muscle relaxation. 6,7,8,9
Flumanazil
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In most animals, including cats, rats and some monkeys, the brain's primary motor cortex controls all movements indirectly through the circuitry of the spinal cord, said researcher Peter Strick, professor of neurobiology at the University of Pittsburgh School of Medicine and Pittsburgh's Veterans Affairs Medical Center. great apes that use tools, another area of the motor cortex developed and is now home to a special set of cortico-motoneuronal (CM) cells, Strick explained.
Livescience.com
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Expression of BECN1, as well as a number of other key genes in the autophagic pathway, declines with ageing in the human brain (T.L. and B.A.Y., unpublished observations), potentially increasing neuronal vulnerability to the toxic effects of protein aggregates.
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Gliosis is linked to neuronal degeneration and may explain the loss of the hypocretin cells.
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Hitherto the conception of chemical transmission at nerve endings and neuronal synapses, originating in Loewi's discovery, and with the extension that the work of my colleagues has been able to give to it, can claim one practical result, in the specific, though alas only short, alleviation of the condition of myasthenia gravis, by eserine and its synthetic analogues.
Sir Henry Dale - Nobel Lecture
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MAIN OUTCOME MEASURES: The cellular density and cross section area of RMS, the expression of polysialylated neuronal cell adhesion molecule (PSA-NCAM)RESULTS: Totally 25 SD rats were recruited.
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Several lines of evidence previously implied that oxidative damage to lipid membranes could disrupt normal neuronal and glial cell functioning, leading to the formation of amyloid plaques and to neuronal cell death.
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Therefore, the present study is to validate the coadministration effects of a neuronal noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist ketamine and astrocytic cytotoxin L-alpha-aminoadipate (LAA) on spinal nerve ligation (SNL) - induced neuropathic pain.
BioMed Central - Latest articles
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His model is a connectionist model illustrating how neural trajectories and multidimensional, neuronal activation vectors drive reason.
Analogy, How Scientifically Powerful is It?
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Most of the bone marrow-derived cells in the brain tissue were glia (support cells) and other non-neuronal cells.
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As a consequence of the inhibition of MAO, biogenic amines can not be converted into catecholamines, causing a drop or deficiency in neuronal catecholamine stores.
Monamine Oxidase Inhibitors
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Hochberg LR, Serruya MD, Friehs GM, Mukand JA, Saleh M, et al. (2006) Neuronal ensemble control of prosthetic devices by a human with tetraplegia.
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Caffeine stimulates the central nervous system, thus increasing neuronal activity and brain function.
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We analysed eye movements and neuronal firing in the abducens nucleus.
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EPR-and light absorbance spectroscopy [3]; mouse macrophage enzyme: cytochrome P-450 type hemoprotein [9]; naturally occuring neuronal mutant with a 105-amino acid deletion in the heme-binding domain as a result of in-frame mutation by specific alternative splicing, contains heme, but shows no l-arginine and NADPH-dependent citrulline-forming activity in presence of Ca2+ - promoted calmodulin, the heme coordination geometry is highly abnormal [28];
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Just as temporal aspects of acoustic resonances underlie the harmonicity of musical sounds, temporal aspects of neuronal correlation mechanisms may explain our preference for harmonic relationships in music.
Balderdash
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A post-mortem study of the animals showed a robust growth of neurons and an increase in neurotransmitters in the spinal cords of rats that received the transplanted neuronal cells.
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Our discovery hinted that the physical forces that mold the gyri and sulci also influence neuronal migration. Developmental studies in humans have bolstered this suggestion.
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That's because while the brain works at slower speeds than a computer, it has 100 trillion interneuronal connections, so it can perform 20 petaflops, while the fastest supercomputer can perform one or two petaflops.
I, Robot
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I felt that designing a dye to measure Ca2+ should be a far easier problem than designing a dye to track fast changes in neuronal membrane potential.
Roger Y. Tsien - Autobiography
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Fuxe, Demonstration of extraneuronal 5-hydroxytryptamine accumulation in brain following membrane-pump blockade by chlorimipramine, Brain Research 12 1969: 456-60.
Alcohol and The Addictive Brain
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Neurosteroids can therefore alter neuronal excitability very rapidly by binding to receptors for inhibitory or excitatory neurotransmitters at the cell membrane.
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Intriguingly, NeuN+ and / or Map2+ neurons showed marked phenotypic defects on the glass surface, characterised by an absence of migration, and poor elaboration of processes and fasciculation among neuronal colonies as compared to REST-100 and REST / KD-50
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Neuronal inflammation and necrosis leads to severe pain or postherpetic neuralgia, which increases as the infection travels down the nerve.
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If aluminium causes direct neuronal death, why would this lead to slowing of conduction along the axons of the optic nerves?
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The synapse is the probable arena where general anesthetics depress neuronal function.
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A post-mortem study of the animals showed a robust growth of neurons and an increase in neurotransmitters in the spinal cords of rats that received the transplanted neuronal cells.
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The neuronal membrane is made up primarily of fats.
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Ed, back up for a minute - are you saying that as a result of the literacy training, the grey matter in the adult sample increased (you wrote: “had more grey matter in five regions towards the back of their brains”) as in somehow added more neuronal cell bodies, neuropil, etc.,
Literacy News – 55th Edition « News « Literacy News
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Our clinical findings suggest that the neuronal disorder may be compensated to some degree because the intestines are richly innervated.
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What goes on in the brain remains to be explored, as does the neuronal mechanism: the researchers plan to develop a protocol that will let them use fMRI to identify the areas of the cortex that are activated during the "multisensory" learning process.
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Individual cells apparently often control similar interneuronal or motor functions from animal to animal, and again, structural and functional parallels often persist across larger taxonomic groups.
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There are proposed explanations for the end-of-life brain activity as non-functional, generalized neuronal depolarization.
Deepak Chopra: End-of-Life Brain Activity - A Sign of the Soul?
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One 2006 study published in Toxicology Science concludes that the combination of several common additives appears to have a neurotoxic effect: "Although the use of single food additives at their regulated concentrations is believed to be relatively safe in terms of neuronal development, their combined effects remain unclear.
Our Deadly, Daily Chemical Cocktail
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The difference in decoded locations (separations) for the 'fixate' and 'saccade' trials are plotted in Theoretical neuronal populations response to a pair of dots.
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Included in this designation are hereditary motor and sensory neuropathy, type I (formerly known as Charcot-Marie-Tooth, type I, or the hypertrophic type of peroneal muscular atrophy); hereditary and motor sensory neuropathy, type II (formerly known as Charcot-Marie-Tooth, type II, or the neuronal type of peroneal muscular atrophy); and distal hereditary motor neuronopathy (formerly known as Charcot-Marie-Tooth, type III, the spinal type of peroneal muscular atrophy, or distal spinal muscular atrophy).
Health News from Medical News Today
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Recent studies have investigated the source and target neurons for the diffusible neuronal messenger molecule nitric oxide in the nervous system of the locust.
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They say that minute amounts of a metal called 'yttrium' may impede neuronal activity.
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The effect of CoCl 2 pretreatment on glucose transport activity of cultured newborn rat hippocampal neurons and its role in neuronal hypoxic tolerance were observed.
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Since failures were not observed when selecting fluorescent spots lying in a row on top of a neuronal process, in later experiments 0.5 M tetrodotoxin was applied to prevent rundown, and the destaining step was omitted.
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Panel A shows a symmetric division of a neuronal unipotent progenitor.
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Elder patients may be susceptible to neuronal loss.
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Homocysteine also causes DNA strand breakage, resulting in mitochondrial membrane damage, nuclear disintegration, and apoptosis of neuronal cells.
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Anti-calbindin antibody labels Purkinje cell bodies and dendritic arbors, while the Nissl counterstain (purple) labels all neuronal cell bodies.
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Hannah has verbal dyspraxia and also a rare neuronal migration, which mean she has difficulty in speaking and is between 18 months and two years behind the expected levels for her age group.
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Walum E, Varnbo I, Peterson A. Effects of dissolved carbon monoxide on the respiratory activity of perfused neuronal and muscle cell cultures.
Carbon Monoxide
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The calcium waves spreading through glial cells may constitute a long-range signalling network acting in concert with conventional neuronal networks.
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The enteric nervous system contains a large number of neurons organized in intricate neuronal circuits.
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The vast excess of neuronal cells present during the early stages of brain development is also eliminated by the same mechanism.
Press Release: The 2002 Nobel Prize in Physiology or Medicine
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The brain consists of millions of interconnected neurons, and cognitive activity reduces, ultimately, to patterns of neuronal excitation and inhibition.
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A neuronal isoform of the aplysia CPEB has prion-like properties.
Of Prions and People - The Panda's Thumb
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Benzodiazepines are believed to potentiate gamma amino butyric acid (GABA) neuronal inhibition.
Flumanazil
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These compounds share with the barbiturates the properties of addiction/habituation, seizure suppression (and withdrawal seizures after prolonged high dosage), and inhibition of spinal interneuronal transmission (muscle relaxation).
The Neuropsychiatric Guide to Modern Everyday Psychiatry
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Tixier E, Coulet F, Roussel S, Petit E, et al. (2007) Crosstalk between HIF-1 and ROCK pathways in neuronal differentiation of mesenchymal stem cells, neurospheres and in PC12 neurite outgrowth.
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There is the real danger of permanent neuronal damage.
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Just recently, scanning tools can see individual interneuronal connections, and watch them fire in real time.
Kurzweil Interview, Arnold Kling | EconLog | Library of Economics and Liberty
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The suspected genes are diverse and encompass multiple functional systems including fibrinolysis, inflammation, vascular reactivity, and neuronal repair.
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Thus, the tip of the leading process actively pulls the soma forward during neuronal migration through a myosin II-dependent forward F-actin flow along the leading process.
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Because of the possibility of eventual neuronal death, the later neurologic consequences of pernicious anemia can be irreversible.
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Neuronal stem cells could be induced to form new connections to repair damage.
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METHODS: The current study analyzed the effects of BDNF on induction of neuronal progenitor cell migration and sensorimotor recovery after cortical photothrombotic stroke.
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Naftolin, A, et al. Neuronal membrane remodeling during the oestrus cycle: a freeze-freacture study in the arcuate nucleus of the rat hypothalemus.
T.S. Wiley: Estrogen Dilemma: There Is No Dilemma When You Know the Details
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Thus, the tip of the leading process actively pulls the soma forward during neuronal migration through a myosin II-dependent forward F-actin flow along the leading process.
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But the scan is not yet at a high enough resolution to recreate the interneuronal connections, synapses and neurotransmitter concentrations that are the key to capturing the individuality within a human brain.
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The expressions of neuronal markers NSE (neural specific enolase), NF (neurofilament), and glial cell marker GFAP (glial fibrillary acidic protein) were detected by fluorescent immunohistochemistry.
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ScienceDaily (Apr. 13, 2010) — In focal epilepsy, seizures are generated by a localized, synchronous neuronal electrical discharge that may spread to large portions of the brain.
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However, behaviors that are outwardly different, such as the lateral bending of Melibe or the parapodial flapping and undulations of Clione and Aplysia brasiliana differ in their neuronal substrate.
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TC-5214 targets a different set of receptors, known as neuronal nicotinic receptors.
Yahoo! News: Business - Opinion
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Histologic examination of the brain showed extensive neuronal loss, gliosis, rarefaction, scarring, and foci of chronic inflammation in multiple brain regions.
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These measurements correlate with neuronal cell count and show a relative reduction of neurons in the epileptogenic hippocampus.
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Fetal Alcohol Syndrome is nonhereditary; alcohol causes neuronal damage and cell loss in the fetal brain through direct action as a toxin.
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Electrophysiological measurements of brain activity play an important role in understanding signal propagation through individual neurons and neuronal networks, but existing technologies are relatively crude: Micropipette electrodes poked into cells are invasive and harmful, and microfabricated electrode arrays are too bulky to detect activity at the level of individual axons and dendrites, the neuronal projections responsible for electrical signal propagation and interneuron communication.
Wired
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Examination of various SNc neuronal markers indicated that neurodegeneration was due to cell loss and not just downregulation of DA synthesis.
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Tonabersat is the leading compound in an exciting new class of selective drugs known as neuronal gap junction blockers, which offer the potential to prevent the onset of migraine as a preferred alternative to acute treatment.
Medlogs - Recent stories
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If aluminium causes direct neuronal death, why would this lead to slowing of conduction along the axons of the optic nerves?
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The terms neuronal and neural also need to be defined.
Undefined
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For many years, neuroscientists have known that two factors, CREB and zif268, activate genes involved in neuronal plasticity and learning.
Scientists Identify Genes Activated During Learning And Memory | Impact Lab
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Conceiably, direct control of neuronal activity with light could someday become a therapy in itself.
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Another strategy was to create "electrochromic dyes" with large changes in dipole moment between ground and excited state, so that a change in neuronal membrane potential could shift the peak wavelengths of absorbance or fluorescence4.
Roger Y. Tsien - Autobiography
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These abnormal responses are generally attributed to the removal of inhibitory signals that influence the interneuronal networks controlling the response.
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It is here, especially, that we need to proceed with caution; if the principle of chemical transmission is ultimately to find a further extension to the interneuronal transmission in the brain itself, it is by patient testing of the groundwork of experimental fact, at each new step, that a safe and steady advance will be achieved.
Sir Henry Dale - Nobel Lecture
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Neuronal circuitry for centrifugal modulation in visual information processing. Visual information is transmitted and processed from the retina to the telencephalon where visual perception results.
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In case 3, however, we noted Purkinje neuronal drop-out, gliosis, and proliferation of microglial nodules in the cerebellar folia.
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Little is known about the neuronal mechanisms that subserve long-term memory persistence in the brain.
I'd Forgotten to Post about this one
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The calcium waves spreading through glial cells may constitute a long-range signalling network acting in concert with conventional neuronal networks.
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Measuring metabolic and neuronal activity at the same time provides direct evidence for this link.
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Through learning and experience, connections are increasingly established between the neurons: by the end of the first three years, the child's brain has twice as many neuronal connections as the adult brain.
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Unlike hypothalamic gangliocytomas, also known as neuronal hamartomas, pituitary gangliocytomas are not attached to the infundibulum or hypothalamus and tend to be endocrinologically active.
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Focal epilepsies are characterized by a condition of neuronal hyperexcitability that is restricted to the epileptogenic region.
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The dark appearance of the caudate nucleus and putamen is attributable to their content of blood vessels and neuronal cell bodies.
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These measurements correlate with neuronal cell count and show a relative reduction of neurons in the epileptogenic hippocampus.
