How To Use Mutagenic In A Sentence
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Recently, it has been suggested that nitric oxide produced during an inflammatory response could become an endogenous cytotoxin, with mutagenic and/or carcinogenic properties.
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Transgenic selection assays provide a unique opportunity to study the mechanisms of mutagenicity in different somatic and germinal tissues in vivo.
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A high sulfur content of the fuel and high engine speeds (rated power) and loads are associated with an increase in mutagenicity of diesel exhaust particles.
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Chronic toxicity may take the following forms: oncogenicity - cancercausing teratogenity - causing deformities in offspring mutagenicity - causing genetic mutations reproductive effects effecting an individual's capacity to bear young
Chapter 12
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This suggests a mutagenic source different from germ cell replication.
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Lange, “Presentation of Benzo(a)pyrene to Microsomal Enzymes by Asbestos Fibers in the Salmonella/Mammalian Microsome Mutagenicity Test,” Environmental Health Perspectives 51 (1983): 337–41.
The Emperor of All Maladies
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A mutagenic oligo containing one of the mutations was annealed to a genome carrying the second mutation, and the oligo was extended using T4 DNA polymerase, essentially as in Sambrook, Fritsch, and Maniatis.
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Among the 22 flavone derivatives tested, only wogonin was strongly mutagenic, while five derivatives, apigenin triacetate, acacetin, chrysoeriol, pedalitin, and pedalitin tetraacetate, were only weakly mutagenic.
Wil's Ebay E-Store
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They used PCR amplification, then mutagenic PCR amplification, then PCR amplification.
A Disclaimer for Behe?
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What is now suggested is that a programme be designed based essentially on short-term studies, that is, chemical analyses of feeding studies in laboratory and/or target species of farm animal, with in vitro or in vivo mutagenicity studies as indicators of possible long-term hazard.
Chapter 26
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We show here that these strains can be used to determine very easily the mutagenic specificity of various mutagens.
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The residues were redissolved in DMSO for analysis of polynuclear aromatic compounds and for the mutagenicity test.
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Consequently, these results demonstrate that CS and MeIQx have a bifunctional action, with similar induction patterns of specific CYP proteins, mutagenic activity and UDPGT activity.
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Additionally, monascus pigments, purpurin, chlorophyllin and curcumin were reported to inhibit the mutagenicity of heterocyclic amines and other carcinogens.
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In practice, the bacterial mutation test is the most widely used and best validated bioassay for assessment of potentially mutagenic contaminants.
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Though the mutagenic activity of ethylene thiourea is well documented, very little is known about the deleterious effects of zineb.
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The nitrous acid produced later in the reaction chain is toxic, corrosive, mutagenic, teratogenic, and carcinogenic.
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If mutations can solve the problem, then a cost-benefit analysis is needed to determine whether a mutagenic mechanism can provide benefits sufficient to counterbalance its cost.
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At present the evidence for hydroxyl radicals being mutagenic is limited.
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Several studies have demonstrated that only the 5-nitrofurans are mutagenic and that derivatives with the nitro group outside the furan ring do not show mutagenic activity.
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Coincidentally with Muller's discovery in 1927 of the mutagenic effect of X rays, Vladimirovich started his long-term investigations of radiation genetics and radiobiology.
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Due to its extreme mutagenic potency, this compound constitutes an interesting model to study the mutagenic action of nitrofurans.
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And mutagenicity is of course a bad thing, because increased DNA damage is generally held to be a factor in carcinogenesis.
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Feeding of freshly irradiated wheat resulted in significantly increased incidence of polyploid cells in bone marrow, aneuploid cells in testis, reduction in number of spermatogonia of types A, B and resting primary spermatocytes as well as a higher mutagenic index.
NUKED FOOD
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Gamma-tocopherol traps mutagenic electrophiles such as NOX and complements alpha-tocopherol: physiological implications.
Craig Cooper: The Real Facts About Vitamin E and Prostate Cancer
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Thus there was some evidence that irradiated PRD diet has weak mutagenic activity in the meiotic and/or pre-meiotic phase of the spermatogenic cycle which appeared to be lessened on storage; the inclusion of such a diet in toxicological studies would therefore need to be carefully considered.
NUKED FOOD
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The resulting soluble organic fractions were analysed for polynuclear aromatic compounds and tested for mutagenic effects.
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Three consecutive rounds with mutagenic PCR amplification were performed with an average mutagenic rate of 3.7% per amino acid for each round.
A Disclaimer for Behe?
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Lead is clearly not a powerful mutagen, nor is it consistently mutagenic among various test systems.
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Potentially harmful polycyclic aromatic hydrocarbons or PAHs for short, heterocyclic amines, and higher and mutagenic aldehydes, along with fine and ultrafine particles, have all been found in cooking fumes, using vegetable oils, such as safflower, soya bean, and rapeseed oils, as well as lard.
PhysOrg.com - latest science and technology news stories
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For example, acesulfame-K induces chromosomal aberrations; sucralose is associated with several effects in animals, is weakly mutagenic, and increases the glycosylated hemoglobin in diabetic patients.
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The tweaking came in later, with mutagenic PCR, again you have to actually read the paper.
A Disclaimer for Behe?
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Particulate matter of diesel engine exhaust from four different fuels was studied for content of polynuclear aromatic compounds and mutagenic effects.
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Gene mutations occur spontaneously and can be induced by mutagenic agents such has high temperature, mustard gas, and radiation.
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The development of transgenic mice has opened up new possibilities for mutagenicity testing in small animal models.
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The finding that phenothiazines reduce the incidence of cancer in humans generated a broad range of experimental studies, which confirmed their antitumor, cancer-chemopreventive and antimutagenic activities.
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The mutagenic activity of 0.05 nmol of BP 7,8-diol-9,10-epoxide-2 towards strain TA 100 of S. typhimurium was inhibited 50% by incubation of the bacteria and the diol-epoxide with myricetin (2 nmol), robinetin (2.5 nmol), luteolin (5 nmol), quercetin (5 nmol),
Wil's Ebay E-Store
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The purpose of this study was to determine if cooked meat containing only moderate concentrations of the known food mutagens would be detectably mutagenic.
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Our urine mutagenicity testing did not provide evidence of increased numbers of bacterial strain revertants.
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Adverse impacts of these chemicals can include mutagenic damage to DNA, cancer, neurological toxicity, reproductive toxicity, developmental toxicity and immune system damage, among others, according to Safer Chemicals, Healthy Families.
Robyn Griggs Lawrence: Toxic Flame Retardants Rampant in Baby Products, New Study Finds
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Some are known carcinogens, some are suspected carcinogens, some are toxic to people, some are toxic to aquatic life, some are mutagenic which means they can cause genetic defects and some have reproductive effects.
The UK's lack of fracking regulation is insane | George Monbiot
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As an indicator of mutagenic activity, we observed an incidence of micronuclei in erythrocytes.
Archive 2008-08-01
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But the World Health Organization reports that "propoxur is not considered mutagenic, embryotoxic, or teratogenic WHO, 2003.
Bill Chameides: Is Propoxur the Way to Not Let the Bedbugs Bite?
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Heterocyclic amines are produced when the meat is cooked at a high temperature and are known to be mutagenic, meaning that they can alter DNA thus increasing the rate of cell production that can lead to cancer.
Emaxhealth
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A rather odd thing has just just occurred in the life of nerdy high school student Peter Parker; after being bitten by a radioactive spider, his body chemistry is mutagenically altered in that he can scale walls and ceilings, and he develops a "spider-sense" that warns him of approaching danger.
Listal promoted
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Gene mutations occur spontaneously and can be induced by mutagenic agents such has high temperature, mustard gas, and radiation.
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Gamma-tocopherol traps mutagenic electrophiles such as NOX and complements alpha-tocopherol: physiological implications.
Craig Cooper: The Real Facts About Vitamin E and Prostate Cancer
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Pollutants in diesel exhausts exist as particles or gas phase compounds and the contribution of nitrated, oxygenated and alkylated PAHs to the mutagenic and carcinogenic activity has been recognized.
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The chlorinated nitrosamines showed stronger mutagenicity than non-chlorinated nitrosamines, indicating that alkylating activity was strengthened by the presence of a chloro group.
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Many carcinogens and mutagens have to be metabolized before their mutagenic activity can be detected.
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For example, many metals, like cadmium, lead, and mercury are toxic to humans and are mutagenic and carcinogenic.
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This cell line detects a wide variety of mutagenic lesions, including point mutations, deletions and various types of chromosomal aberrations.
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The tweaking came in later, with mutagenic PCR, zach:
A Disclaimer for Behe?
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Once pregnancy has progressed into the second trimester and once children reach puberty, the dangers of food poisoning and foodborne illnesses may again outweigh the mutagenic risks associated with phytochemicals (Flaxman and Sherman in press).
Archive 2005-06-01
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The first step is a qualitative evaluation of all available epidemiology studies, animal bioassay data, and biological activity (e.g., mutagenicity).
Risk assessment of chemical substances
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Substances which allow the Salmonella to grow are considered mutagenic.
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It is also accepted that a percentage of cancer patients develop secondary tumors after being treated with mutagenic agents such as cytostatic drugs.
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Epoxy compounds are highly reactive bifunctional alkylating agents, which may attack and bind covalently to DNA and cause mutagenic events.
