How To Use Lysosome In A Sentence
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Although this 21-chapter book is an excellent review, it at first look appears to be mistitled, as it only deals with the more common lysosome-, peroxisome-, and mitochondrion - based diseases.
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For instance, within the individual cell, the subcellular sites of photo-damage may include the plasma membrane, the lysosomes and the mitochondria.
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Lysosomes are intracellular organelles that specialize in breaking down cellular waste.
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A primary pathway for the uptake of mitochondrial sequences by the nucleus may be provided by autophagy of mitochondria in cellular vacuoles (lysosomes).
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The spindle cell population consisted of bipolar cells with large oval nuclei that contained macronucleoli and scattered rough endoplasmic reticulum, mitochondria, and lysosomes within their cytoplasm.
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In the phagosomes, lysosomes are activated and fuse with the apoptotic bodies, bringing on their dissolution.
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Furthermore, recent studies from this laboratory have shown that experimental ethanol administration increases the fragility of rat pancreatic lysosomes.
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NgHexA was more efficiently taken up than the wild-type HexA and delivered to lysosomes, where it degraded accumulated substrates including GM2 ganglioside (GM2) when administered to cultured fibroblasts derived from a Sandhoff disease (SD) patient.
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These enzymes participate in the degradative process of compounds taken up by lysosomes.
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In the animal cell there are many things the instruction manuel is the DNA protein factory is the ribosome recycling center is the lysosome gift wrapping and shipping center is the golgi complex DNA is stored and maintains in the nucleus (x) the mitochondria converts glucose into usable energy tokens tubes and fibers make the cytoskeleton the flexible outer skin is the cell membrane the smooth endoplasmic reticulum is where lipids are made vesicle delivers the proteins the cytosol is the slimy filling the rough endoplasmic reticulum helps ribosomes make and fold proteins those are the parts of the animals cell hope you like our song, ciao farewell!!!!!!!!!!!
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Lysosomes contain enzymes which digest and modify material brought into the cell by endocytosis.
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Cysteamine enters the lysosomes by a specific transporter and converts cystine to cysteine and cysteine-cysteamine mixed disulfide.
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Epithelial cell reticulum expansion, reduced microvilli, chromosome concentration, increased lysosome.
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In addition, low relative molecular mass proteins (less than 60,000Da), as well as low concentrations of albumin, that were able to penetrate the layers in the renal corpuscle are removed by pinocytosis, followed by degradation by hydrolytic enzymes in lysosomes.
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Thus, the photodamaged lysosomes and the normal ones will suffer the same level of osmotic stress in the same hypotonic sucrose medium.
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TPP1 is synthesized as an inactive proenzyme (pro-TPP1) that is proteolytically processed into the active enzyme after exposure to low pH in vitro or targeting to the lysosome in vivo.
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This mutant, in contrast to the wild-type bacterium, was shown both to have impaired the ability to replicate within macrophages and to have prevented phagosome/lysosome fusion.
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The cytoskeleton is involved in the saltatory movement of organelles such as mitochondria or in the fusion of endosomes with primary lysosomes.
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With their modification, which they call the lysosome patch clamp, Xu's group was able to record TRPML1 activity in the tiny lysosome.
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Based on this mechanism, other phenomena related to receptor and ligand recycling to the cell surface or targeting to the lysosome could be explained, which are also due to the pH difference between the external environment and the interior of the endocytic pathway vesicles.
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Alternatively, the crystalloid structures could be in the process of degradation within the lysosomes.
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To discover the mechanism that drives ganglioside-mediated protection from a-synuclein-caused cell death, Wei et al treated cells with a molecule that disrupts the function of lysosomes, cell components responsible for digesting unneeded and excess material in cells.
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The enzyme is present in lysosomes, where it helps break down mucopolysaccharides.
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This effect allows aspirin to inhibit granulocyte adherence to damaged vasculature, stabilize lysosomes and inhibit the migration of polymorphonuclear leukocytes and macrophages to the site of inflammation.
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Furthermore, it is not enough simply to treat patients with recombinant enzymes - modifications must be made so that the infused enzyme is targeted to lysosomes in relevant cells and tissues.
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Forum: Science Jobs Forum Posted By: Jessica Post Time: 10-29-2008 at 10: 18 PM what role do lysosomes play in apoptosis, digit formation, and syndactyly?
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In all eukaryotic cells the lysosomes or vacuoles play major cellular turnover roles, including autophagy where entire organelles are delivered to them for turnover.
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These authors, by using differential and density-gradient centrifugation techniques, achieved the differentiation of the microbody fraction from lysosomes, microsomes, and mitochondria.
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Energy production takes place within mitochondria, the power plant of the cell; the breakdown and recycling of waste takes place in the lysosome etc. The production of new products, proteins in the case of the cell, is carried out by ribosomes in a process resembling an assembly line.
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Acid hydrolases of the lysosomes degrade the apoproteins and release free fatty acids and cholesterol.
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Loss of GlcNAcT-IVa, or the addition of glycan-ligand mimetics, attenuates Glut-2 cell-surface half-life, provoking endocytosis with redistribution into endosomes and lysosomes.
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Intact lysosomes, mitochondria and microsomes were isolated from RPE cells.
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These protein and lipid molecules are then transported inside lysosomes -- minute, balloon-like sacs within the cell.
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After internalization of organisms into phagosomes, secondary lysosomes are fused to form the complete parasitophorus vacuole.
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These efforts have successfully identified mitochondria, lysosomes and various cytoplasmic membranes as among the primary targets of PDT-mediated damage, depending on the particular photosensitizer.
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With their modification, which they call the lysosome patch clamp, the researchers determined that a protein called TRPML1 serves as the calcium channel in lysosomes and that a lipid known as PI (3,5) P2 carries the signal that activates the protein.
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