How To Use Liposarcoma In A Sentence
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Almost 20 percent of the myxoid liposarcoma tumors studied had a mutated form of the gene PIK3CA.
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Less than one year after resection of a myxoid / round cell liposarcoma of the left lateral calf, a 61-year-old male presented with a CT scan showing a 2 cm low-density lesion in the right lobe of the liver.
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To study the genetic changes in dedifferentiated liposarcomas, paired well-differentiated and dedifferentiated components of 29 tumors were analyzed separately by array-based comparative genomic hybridization.
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Liposarcoma represents a unique model insofar as some well-differentiated liposarcomas progress to non-lipogenic, so-called 'dedifferentiated,' forms.
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Microscopically, it has a mixture of collagenized vascular tissue, clusters of adipocytes, and myxoid areas with spindle cells resembling a well-differentiated or myxoid liposarcoma.
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An abundant, granular, myxoid background can also be seen in myxoid liposarcoma, but the cells are monomorphously spindle / stellate.
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The lesion was surgically removed with a right hepatic lobectomy and the pathology was consistent with metastatic myxoid / round cell liposarcoma.
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In other sites, liposarcoma is thought to be derived from residual rests of primitive mesenchymal tissue.
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Type (full-length or truncated) and level of expression varied with morphology and karyotype, with the highest levels in atypical lipomatous tumors and lipomas with rearrangements of 12q13-15 and the lowest in lipomas with 6p - or 13q-rearrangements, hibernomas, spindle cell lipomas and myxoid liposarcomas.
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