NOUN
- (genetics) a mutation caused by the insertion of exogenous DNA into a genome
How To Use insertional mutagenesis In A Sentence
- It has a wide cell tropism and remains extra-chromosomal, therefore minimising the risk of insertional mutagenesis.
- For example, SINES and LINES can cause insertional mutagenesis, hybrid dysgenesis, chromosomal rearrangements, etc. Junk DNA, Junk Science, and The Onion Test - The Panda's Thumb
- A feasible way to decrease the risk of insertional mutagenesis is to combine the reprogramming factors into a single polycistronic vector by inserting a 'self-cleaving' 2A peptide or an internal ribosome entry site (IRES) sequence between two consecutive open reading frames. BioMed Central - Latest articles
- Insertional mutagenesis is a method for identifying genes by using the integration of DNA as the mutagen , thereby facilitating the cloning of the mutated gene.
- The FeLV-induced tumors are thought to be caused, at least in part, by somatically acquired insertional mutagenesis in which the integrated provirus may activate a proto-oncogene or disrupt a tumor suppressor gene.
