How To Use Inhibitor In A Sentence
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Lefebvre V, Peeters-Joris C, Vaes G. Modulation by interleukin 1 and tumor necrosis factor alpha of production of collagenase, tissue inhibitor of metalloproteinases and collagen types in differentiated and dedifferentiated articular chondrocytes.
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BDC is currently conducting a Phase two placebo-controlled proof of concept study with the tumor necrosis factor (TNF) inhibitor, etanercept, epidurally administered to a minimum of 40 patients with sciatica.
THE MEDICAL NEWS
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Activated ROCK induces neurite retraction [5] while selective ROCK inhibitor, Y-27632, as well as ROCK dominant negative mutants promote neurite formation
PLoS ONE Alerts: New Articles
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Sanofi's treatment leads a new family of medicines known as parp inhibitors, designed to prevent breast cancer from repairing itself after being blasted by chemotherapy.
BusinessWeek.com -- Top News
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In addition, the dorsal central column of primary afferent fibers within the spinal cord appears susceptible to the inhibitory effects of hypoxia in rats.
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MAO inhibitors are commonly prescribed by medical doctors to treat depression.
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A number of the older tricyclic antidepressants, typical neuroleptic medications and, more recently, selective serotonin reuptake inhibitors have been trialed in eating disorders.
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This is of clinical relevance because cyclosporine A is a known inhibitor of calcineurin.
Urology Division Research
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There are two main classes of antidepressant used for treating cataplexy - the Tricyclic antidepressants and the Selective Serotonin Reuptake Inhibitors (SSRIs).
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Conclusion: 9.1 C 3 molecule is a kind of killing cell inhibitory receptor.
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Horses Mouth January 22, 2007 4:24 PM
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There are other kinds of generalized seizures that are basically inhibitory, like briefly turning off a switch.
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Standard, first-line OCD treatment typically includes selective serotonin-reuptake inhibitors (SSRIs) and tricyclic antidepressants such as clomipramine, along with behavioral therapies.
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-- (BUSINESS WIRE) -- Apr 8, 2009 - KAI Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced the Company has initiated a third Phase 2a study of KAI-1678, a first-in-class, isozyme-selective, small peptide inhibitor of the epsilon protein kinase C pathway (epsilon PKC).
Undefined
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Yes, indeed, guns are fired before leaving the factory and a rust inhibitor is often applied to the exterior and the bore after testfire.
Dirty guns sold as new
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I agreed to be put on an SSRI, a selective serotonin reuptake inhibitor.
Blogging About Anti-Anxiety Meds
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The clinical use of HMG CoA-reductase inhibitors and the associated depletion of coenzyme Q10: A review of animal and human publications.
Hyla Cass, M.D.: Is Your Medication Robbing You of Nutrients Part 2: Getting Specific
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His work has established the inhibitory role astrocytes can play in preventing central nervous system regeneration.
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Elidel belongs to a class of drugs known as calcineurin inhibitors, so called because they reduce immune activity by inhibiting the activity of the enzyme calcineurin.
FDA Runs Protection Racket For Big Pharma
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In the new research, published in the journal, Annals of Rheumatic Diseases, patients were taking either a high dose of lumiracoxib, a type of drug known as a cox-2 inhibitor, high dose of ibuprofen or naproxen, which are both non-steroidal anti-inflammatory drugs known as NSAIDs.
The Down-Side of Pain Killers | Impact Lab
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The FDA is advising doctors to weigh the benefits against risks when prescribing Cox - 2 inhibitors for their patients.
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It is used as a corrosion inhibitor, a plasticizer, and a lubricant, as well as an ingredient in a variety of polymers and personal care products.
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Oilseeds often contain toxic or undesirable factors such as gossypol in cottonseed, trypsin inhibitor in soya beans and cyanogenetic glucosides in linseed, whereas groundnuts have been noted as being particularly vulnerable to mycotoxin formation.
Chapter 6
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In other words, the function of one organ could have facilitatory as well as inhibitory actions on other organs via their connections, namely meridians, blood, and qi (vital air).
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Acetylcholine esterase inhibitor (neostigmine): indications: colonic pseudo-obstruction
PLoS Medicine: New Articles
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We coded all drugs according to the British National Formulary and defined secondary prevention drugs as aspirin, blockers, lipid lowering agents, or angiotensin converting enzyme inhibitors.
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The patient was put on a liquid diet, sucralfate proton pump inhibitor treatment and was symptom-free within two weeks.
BioMed Central - Latest articles
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Like the skin comparison neurons in the spinal cord, the center may be excitatory and the surround inhibitory.
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When those rust inhibitors lose their effectiveness, the inside of the radiator can start to corrode.
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Fortunately, the inhibitory salt effect can be alleviated in vivo by natural DNA supercoiling.
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All three drugs are variations on the same theme - they are known as PDE5 inhibitors - but with different side effects.
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Fischler and Bloom conclude from these results that in visual word recognition the effect of context is essentially inhibitory rather than facilitatory.
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The lack of enterprise space in the town is a major inhibitor to the development of new businesses.
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As indicated previously, intracellular calcium is usually an inhibitor of adenylate cyclase, but this is not invariably the case.
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It seems that the failure of the axons to regenerate is partly the result of an inhibitory effect exerted by central nervous system glial cells, associated with the myelin of nerve fibers.
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Kuntz DA, Hoffman D, Janzer RC, Gerber-Lemaire S, et al. (2008) Functionalized pyrrolidine inhibitors of human type II alpha-mannosidases as anti-cancer agents: Optimizing the fit to the active site.
PLoS ONE Alerts: New Articles
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Retinoic acid, tamoxifen, and the two telomerase inhibitors each significantly squelched immortalization.
The Scientist
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While the combined use of Hypericum with orthodox medications has even shown an increased favorable response, it is advisable to exert some cautious watchfulness with the prolonged usage of St. Johnswort with serotonin reuptake inhibitors (SSRI) and monoamine oxidase inhibitors (MAOI).
THE NATURAL REMEDY BIBLE
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Some of the calcium channel blockers also exert an inhibitory effect on the sinus and atrioventricular nodes, causing the heart rate to slow.
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Thus, the bile itself seemed to be the inhibitory agent in the venous effluent.
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Aim To investigate the cytotoxic activity of HDAC inhibitor Trichostatin A (TSA)combined with anticancer drugs targeting DNA on T24 bladder cancer cell line.
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They commissioned a study of the possible military uses of calmative pharmaceuticals such as anesthetics and serotonin reuptake inhibitors.
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While not depicted here, it is suggested that the inhibitory input to these DA pathways produces the overt and covert restlessness characteristic of akathisia.
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Another type, called selective serotonin reuptake inhibitors (SSRIs) work by slowing down the reuptake process.
Skip the Prozac and Spring Cleaning! Get Dirty! | Impact Lab
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The results of bacteriostatic experiment of anthocyanins from purple sweet potato indicated that their minimum inhibitory concentration (MIC) on Staph.
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As a measure that everyone could recognize, clinicians and researchers used the minimum amount of drug needed to kill bacteria, expressed as milligrams of drug per liter of blood, which they called the minimum inhibitory concentration, or MIC for short.
SUPERBUG
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Importantly, the team found that EGCG only reacted with proteasome inhibitors that have a boronic acid base (including bortezomib) but did not react with several non-boronic acid-based proteasome inhibitors (such as nelfinavir [Viracept®], a treatment for HIV).
Innovations-report
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The treatment with both cycloheximide and MG132, a proteasome inhibitor, showed that the stability of FOXL2 is dependent on the co-transfection with SUMO-1.
PLoS ONE Alerts: New Articles
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This inhibition was observed in both the directly and indirectly stimulated contractions, and was not changed by addition of neostigmine, an acetylcholine esterase inhibitor.
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Guanidine consequently is a specific inhibitor of the poliovirus.
André Lwoff - Nobel Lecture
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For the first time, we observe that the acyl binding site of cholesterol esterase shows stereospecificity for diastereomeric inhibitors.
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A study was done to determine if various organic acids differ in their inhibitory or lethal activity against acid-adapted and unadapted Escherichia coli.
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And some research suggests that the drugs — memantine (Namenda), and cholinesterase inhibitors such as donepezil (Aricept and generic) and galantamine (Razadyne and generic) — may be more effective when taken together.
Brain boosters in a bottle?
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MGCD290 is an oral, small molecule, Hos2 fungal inhibitor for use in combination with azoles, such as fluconazole, for fungal infections.
Marketwire - Breaking News Releases
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-- On December 14, 2009 - Ipsen announced the preliminary results of a phase I trial in metastatic breast cancer with BN83495, Ipsen's lead and first-in-class orally available irreversible steroid sulfatase (STS) inhibitor.
StreetInsider.com News Articles
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It's an inhibitor, a barrier that we don't feel we need here in Chippenham.
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This indicates the presence of an inhibitory surround.
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Objective To examine the function of ornithine decarboxylase antizyme inhibitor ( Oazin ) gene in the mouse development.
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Can you use tamoxifen or an aromatase inhibitor to prevent breast cancer in the first place?
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Those results, as well as data on a class of drugs known as dipeptidyl peptidase IV inhibitors DPIV, could provide a catalyst for OSI shares, the Wachovia analyst said.
OSI's Macugen Still Burdened By Lucentis Threat
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Kidney beans also contain protease inhibitors which frustrate the development of cancerous cells.
Green Bell Pepper stuffed with Kidney Beans
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Adverse drug reactions are possible if the drug is an inhibitor of CYP isoenzymes and disrupts enzyme function.
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The only synaptic feedback to the pyloric pacemaker group through the EP to PD inhibitory synapse was removed by applying 10-5 M picrotoxin in the bath.
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Results The globin hydrolysate which fully contained small molecule peptide showed the highest ACE inhibitory activity and some hemagglutinative activity with the degree of hydrolysis of 12.6%.
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The FDA is expected to decide soon on telaprevir, another so-called protease inhibitor from Vertex Pharmaceuticals Inc. and Johnson & Johnson .
FDA Clears Merck Hepatitis Drug
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However, in other cases, it may be associated with a biochemical and/or physiological defect in the brain of the patient with epilepsy presumably due to an imbalance of excitatory and inhibitory neurotransmitters.
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Whether the chemical is alcohol, narcotics, cocaine, or nth-generation selective serotonin reuptake inhibitors, their effects tend to become blunted over time.
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Drugs against anxiety act for instance on certain inhibitory ionic channels in the brain.
Physiology or Medicine 1991 - Press Release
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Reverse that action, and through the force of our own inhibitory power let a new pain be a reminder to us to _let go, _ instead of to hold on, and by decreasing the strain we decrease the possibility of more pain.
Power Through Repose
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Proteinase inhibitors, affecting trypsin and chymotrypsin, have been found in seeds of A. cowleana and other species. but only at levels similar to those found in peas or beans-much lower than levels in soybeans or winged beans (Kortt, 1984).
Chapter 48
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The FDA warns that concomitant administration of amiodarone or other CYP2C9 inhibitors (eg, fluconazole) with carvedilol may enhance the beta-blocking properties of carvedilol and lead to further slowing of the heart rate or cardiac conduction.
TheHeart.org
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OBJECTIVE: To study the feasibility and safety of serotonin (5-HT) reuptake inhibitor in the adjunctive therapy of the patients with OAB.
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Objective:To investigate the renal expression of macrophage migration inhibitory factor(MIF)in lupus nephritis and its correlation with renal injuries.
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The experimental results show that 1,2-Octanediol has inhibitory effect on gibbsite precipitation by adsorption on the surface of seeds.
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General Chemical is a leading producer of such commodities as soda ash and calcium chloride, while Garratt-Callahan makes higher value goods such as biocides, and corrosion and scale inhibitors.
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For this reason, the synthetic hormones are technically known as ovulation inhibitors.
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Fischler and Bloom conclude from these results that in visual word recognition the effect of context is essentially inhibitory rather than facilitatory.
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Cholinesterase inhibitors, which reduce cholinesterase - the enzyme that breaks down acetylcholine - are the only FDA-approved treatment for Alzheimer's.
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Aim To investigate the cytotoxic activity of HDAC inhibitor Trichostatin A (TSA)combined with anticancer drugs targeting DNA on T24 bladder cancer cell line.
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Seeing that it’s involved in inactivation/metabolism of norepinephrine and dopamine (neurotransmitters), this may be similar in effect to reuptake inhibitors or catecholamine agonists ... you know, like amphetamines ....
The Volokh Conspiracy » Some Scientists’ Openness to the Possibility of Genetic Differences in Mental Traits Among Racial and Ethnic Groups
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To answer this question, they first compared the levels of thrombin-activatable fibrinolysis inhibitor in bronchoalveolar fluid and in plasma.
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Researchers are investigating whether aromatase inhibitors can prevent breast cancer.
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The high level of plasma gastrin in PA is quite appropriate in view of the absence of the inhibitory effect of HCl on the secretion of antral gastrin.
Nobel Lecture Radioimmunoassay: A Probe For Fine Structure Of Biologic Systems
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Therefore, intervention with hypotensive drugs other than angiotensin converting enzyme inhibitors should be considered.
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After treatment in the HR condition, cytotrophoblast cells were lysed in a cold RIPA buffer (Pierce Biotechnology) containing a protease inhibitor cocktail (Roche).
PLoS ONE Alerts: New Articles
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However, one powerful advantage of endogenous angiogenesis inhibitors is the lack of side effects.
The Scientist
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Either of these receptors has an excitatory or inhibitory effect on the end organ.
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The chemical/petroleum processing industry is a heavy user of water treatment chemicals, ranging from corrosion inhibitors to coagulants / flocculants.
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Aromatase inhibitors are drugs that reduce the levels of estrogen in your body.
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-- On November 25, 2009 - Ipsen announced the initiation of an international, multi-center, controlled, randomized Phase II clinical trial to evaluate the safety and efficacy of BN83495, its investigational first-in-class steroid sulfatase (STS) inhibitor, in advanced endometrial cancer.
StreetInsider.com News Articles
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The new oil is formulated with high-quality Group II base stocks and uses a proprietary, premium additive package containing ashless dispersants, oxidation inhibitors, metallic detergents and a metallic anti-wear agents.
Business Wire Travel News
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You insist that you alone gave the go - ahead for the promicin inhibitor program. Is that right, sir?
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Tim Foley Alzheimer's disease is often treated by a class of drugs called cholinesterase inhibitors, which help boost levels of a brain chemical called acetylcholine.
Drug Cocktail May Slow Alzheimer's
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Proton pump inhibitors (PPIs), such as Prevacid and Prilosec, which suppress gastric acid production, are routinely prescribed to combat the potential GI side effects of heart disease treatment.
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It was the first test in healthy women of newer hormone-blocking pills called aromatase inhibitors, sold as Arimidex, Femara and Aromasin, and in generic form.
Breast Cancer Risk May Be Cut With Hormone-Blocker Aromasin In Some Groups
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The endorphins function as inhibitory neurotransmitters and neurohormones: they are released from nerve cells to act on other cells that bear opioid receptors and thus dampen the activity of those cells.
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Corsini, A, et al. Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMGF-CoA reductase.
T.S. Wiley: Estrogen Dilemma: There Is No Dilemma When You Know the Details
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Angiogenesis inhibitors are also used to treat macular degeneration, a common cause of blindness.
Times, Sunday Times
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Study participants were 9-year-olds eight girls, 12 boys who performed a series of stimulus-discrimination tests known as flanker tasks, to assess their inhibitory control.
Physical Activity May Strengthen Children’s Ability To Pay Attention | Impact Lab
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Current treatment involves the use of drugs such as donepezil, tacrine, rivastigmine, galanlamine etc which act as choline esterase inhibitors.
Remembering Dr. Alois Alzheimer
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This stretch is made possible by the presence of nitrergic inhibitory nerves, excited in a swallow, in both longitudinal muscle layers within this short segment.
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DFMO is an inhibitor that specifically targets a key protein called ornithine decarboxylase
Medlogs - Recent stories
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Medicines called ACE inhibitors and angiotensin-II receptor blockers are helpful.
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Additionally, ovarian differentiation can be altered by embryonic exposure to a inhibitor of aromatase, the enzyme essential for estrogen synthesis.
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It is becoming evident however that some strains that appear to have similar spectra of inhibitory activity produce quite different bacteriocins.
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Moreover, this method has the advantage of not needing to discover an inhibitor for every oncoprotein.
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The inhibition of proteinases by protein proteinase inhibitors is an individual case of protein-protein interaction.
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First, sodium lauryl sulfate and EDTA were put into the prepared complex inhibitor at the rate of 1:1 in mass.
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Some currently circulating H5N1 strains are fully resistant to these the M2 inhibitors. However, should a new virus emerge through reassortment, the M2 inhibitors might be effective.
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The mutation results in loss of RAD51 focus formation in response to DNA damage and in increased cellular sensitivity to the DNA interstrand cross-linking agent mitomycin C and the topoisomerase-1 inhibitor camptothecin.
Naturejobs - All Jobs
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Atrial fibrillation is less common among hypertensive patients taking long-term monotherapy with ACE inhibitors, angiotensin II-receptor blockers (ARBs), or beta-blockers than among those on calcium channel blockers, the
Medlogs - Recent stories
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Results of the study** show that combined use of glucosamine and chondroitin are of benefit to breast cancer patients experiencing joint pain and stiffness related to the use of aromatase inhibitors.
Dr. Nalini Chilkov: Natural Relief From Breast Cancer Treatment Side Effects: Joint Pain
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The combination therapy of one protease inhibitor and two nucleoside transcriptase inhibitors has markedly increased the number of CD4 cells and decreased the viral load of patients.
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Apoptosis modulators such as caspase inhibitors might one day come close to curing acute brain injury.
The Scientist
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Corrosion inhibitors protect metal equipment and piping from the effect of prolonged contact with water.
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Oilseeds often contain toxic or undesirable factors such as gossypol in cottonseed, trypsin inhibitor in soya beans and cyanogenetic glucosides in linseed, whereas groundnuts have been noted as being particularly vulnerable to mycotoxin formation.
Chapter 6
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Progress has been made in the development of new anti-emetic drugs (emesis = vomiting), particularly the serotonin antagonists which are potent inhibitors of chemotherapy-induced vomiting.
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I parametrically simulate all of: both short and long term potentiation from digital signal frequencies, axonial growth and destruction, formation of excitatory or inhibitory receptors, as appropriate (based on source neurotransmitter type or if it is a correlate verses anti-correlate interconnection).
MachineMachine (formerly 'The Huge Entity')
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Auspex Pharmaceuticals, a developer of next-generation medicines with improved safety and performance through the targeted deuteration of clinically validated drugs, today announced positive results from its Phase 1 clinical trial evaluating SD-254, a Selective Serotinin-Norepinephrine Reuptake Inhibitor (SNRI).
Medlogs - Recent stories
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For example, ACE inhibitors, beta-blockers, ARBs, spironolactone and digoxin are probably not necessary in all patients.
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Treatment includes strict plasma glucose control to achieve and maintain normoglycemia and administration of angiotensin converting enzyme inhibitors to decrease the progress of diabetic nephropathy.
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Objective To disclose the changes in pathophysiology of cardiovascular deconditioning(CVD) induced by tail-suspension(TS) and to explore the effects of NOS inhibitor on CVD in TS rats.
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Two kinds of motor nerves, excitatory nerves that release acetylcholine and inhibitory nerves that release nitric oxide, account for all events that occur in smooth muscle of the esophagus in a swallow.
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Isolation and identification of a new growth inhibitor, Raphanusanin, from radish seedlings and its role in light inhibition of hypocotyl growth.
Chapter 27
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Like the skin comparison neurons in the spinal cord, the center may be excitatory and the surround inhibitory.
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Study the inhibitory effect and the mechanism of helleborus thibetanus france. Polysaccharide(HFPS) on tumor growth.
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Goss PE, Reid CL, Bailey D, Dennis JW (1997) Phase IB clinical trial of the oligosaccharide processing inhibitor swainsonine in patients with advanced malignancies.
PLoS ONE Alerts: New Articles
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No mutations were detected associated with resistance to multinucleoside or nucleotide reverse transcriptase inhibitors, such as Q151M or insertions at codon 69.
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In addition, using emetine (a translation inhibitor altering ribosome functioning) we detected the involvement of ribotoxic stress in p38 MAPK activation by UVA.
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Conclusion The extracts of Illicium lanceolatum A . C . Smith have obvious inhibitory effect against two usual bacteria.
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But in the end these elements only really came into play in the final episode and they weren't really inhibitors.
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The strongest AMD genetic association found in the study was in a region on chromosome 22, near a gene called metalloproteinase inhibitor 3 (TIMP3).
Analysis
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Production was not abrogated by inhibitors of cyclooxygenases, xanthine oxidase, nitric oxide synthases, and mitochondrial enzymes.
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Boceprevir, a protease inhibitor, along with peginterferon and ribavirin increases response rates in previously untreated patients," said Dr. Raj Reddy, co-researcher of one of the studies and director of hepatology and medical director of liver transplantation at the University of Pennsylvania in Philadelphia.
New drug may boost hepatitis C treatment
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Because other small molecule inhibitors of Hsp90, including celastrol, novobiocin, and EGCG, are thought to bind Hsp90 at the carboxy-terminus
PLoS Biology: New Articles
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But in spite of these inhibitors, there is a promising development around intelligent switches.
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Those that make you happy, relaxed, and peaceful are called inhibitory neurotransmitters.
The UltraMind Solution
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Individual muscle fibers may be innervated by one or both of the excitatory neurons, and generally receive inhibitory input as well.
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There are three broad classes of corrosion-inhibiting admixtures, using different chemical mechanisms to control oxidation and the resulting corrosion - anodic inhibitors, cathodic inhibitors, and organic inhibitors.
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This result is in accordance with functional data showing that axon growth inhibitory molecules are less prominent in fish oligodendrocytes and CNS myelin compared to mammals.
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With small tweaks in design, the DHFR inhibitors can have antibacterial, antifungal and antiprotozoal properties, says Anderson.
PhysOrg.com - latest science and technology news stories
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One piece with which Milne was pleased was his clarification of the tyramine monoamine-oxidase inhibitor interaction (the ‘cheese reaction’).
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We also find that PMA and LPS increase the level of hres mRNA while pyrrolidine dithiocarbamate (PDTC), which is an inhibitor of Sp1 binding, abrogates the basal, and also PMA/LPS induced resistin mRNA levels.
PLoS ONE Alerts: New Articles
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Treatment B inhibitor pyrollidine dithiocarbamate or the resveratrol analog CAY10512 abrogated this response.
Journal of Biological Chemistry current issue
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Despite a variety of drugs that include pills such as diuretics, beta blockers and ACE-inhibitors, only about a third are successfully treated.
Old Blood-Pressure Treatments Make High-Tech Comebacks
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The B genes act as awn inhibitors, A acts as awn promotors, b 1 a leads to half awned condition and Hd gives hooded condition.
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Erlotinib is a small molecule tyrosine kinase inhibitor that efficiently blocks EGFR.
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The trial compares AS1413-based treatment with standard current treatment based on the classical TopoII inhibitor daunorubicin.
Marketwire - Breaking News Releases
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By contrast with their failure to affect habituation, the protein synthesis inhibitors did produce amnesia for associative learning.
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Both Incivek and Victrelis are known as protease inhibitors, designed to block an enzyme that helps the hepatitis C virus replicate.
Hepatitis C Drug Approved
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The COX-2 inhibitor celecoxib brand name Celebrex led to a 62 percent reduction in non-melanoma skin cancers, which includes basal cell carcinomas and squamous cell carcinomas.
Daily Dispatch: Multiple social identities may be theme of 2011; USA Today buys electronics review site
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What's different, at least for journalists in Iraq today, is that the viciousness and brutality is a much greater inhibitor to work.
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Such a move could often be viewed as a capital inhibitor.
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Legal rules may well be used presentationally, rather than being operational working rules or inhibitors.
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EU and Japan USPTO issues Notice of Allowance for menadione to prevent skin rash in patients taking EGFR inhibitors Premier Purchasing Partners announces new agreements for orthopedic power tools and accessories Kaiser Permanente to deploy solar power systems at 15 facilities across the state New cakes and frostings may someday contain less fat and calories
THE MEDICAL NEWS
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Objective To investigate the inhibitory effect of electropuncture on epileptic petit mal and its underlying mechanism.
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If the memory loss is severe enough to warrant a diagnosis of dementia, then cholinesterase inhibitor therapy would be indicated.
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The selective serotonin reuptake inhibitor fluoxetine is effective in this age group.
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This notion is also supported by the observation that substitution of salubrinal with subtoxic concentrations of the phosphatase inhibitor cantharidin induced a comparable increase in PSI-mediated cytotoxicity, whereas the PP2B / calcineurin inhibitor cypermethrin proved to be ineffective.
PLoS ONE Alerts: New Articles
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The mechanism responsible for the inhibitory action of hyperglycaemia on gall bladder motility is not known.
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We restricted our analyses to loop diuretics, angiotensin converting enzyme inhibitors, blockers, spironolactone, and digoxin.
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This tonic contraction is mostly myogenic, due to special properties of this smooth muscle, but it is modified by excitatory and inhibitory nerves.
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The most serious adverse reactions are systemic hypersensitivity reactions including bronchospastic reactions and / or hypotension and anaphylaxis and the development of high-titer inhibitors necessitating alternative treatments to AHF.
BioSpace.com Featured News and Stories
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These inhibitors can potentiate the hypotensive effects of nitrates and alpha blockers.
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Also, I am not sure I would call the fugu non-catalytic domain “inhibitory”, as opposed to simply non-functional or not fully functional in mammalian cells.
3 recent reports use evolution to study mechanisms of antibody diversification - The Panda's Thumb
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A group of estrogen-blocking drugs called aromatase inhibitors have proven effective in preventing breast cancer from recurring after surgery.
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Current treatment involves the use of drugs such as donepezil, tacrine, rivastigmine, galanlamine etc which act as choline esterase inhibitors.
Remembering Dr. Alois Alzheimer
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This ratio suggests that the enzyme-inhibitor complex can be described as prolate ellipsoid, for reasons discussed before.
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In 1970, I had begun work on the basic pancreatic trypsin inhibitor which has later become the model compound for the development of protein NMR, molecular dynamics, and experimental folding studies in other laboratories.
Robert Huber - Autobiography
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The main ones prescribed are selective serotonin reuptake inhibitors.
Times, Sunday Times
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Therapeutic trials include those with proton pump inhibitors, prokinetic agents, mucosal protectants, anticholinergics and low-dose antidepressants.
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Gumperz JE, Parham P, Long EO, Wagtmann N (1998) Direct binding and functional transfer of NK cell inhibitory receptors reveal novel patterns of HLA-C allotype recognition.
PLoS ONE Alerts: New Articles
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This inhibitory effect is most strongly observed for alternating tasks, resulting in an alternating-switch cost that is discriminable from switch cost per se.
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The question exists as to why both the lidocaine and the placebo saline solution would have an inhibitory effect on muscle-firing characteristics.
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An attack of inherited angioedema is treated with an injection of the C1 inhibitor, the substance that your body is deficient in.
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This literature mainly comprises the variation in genes for blood coagulation factors, inhibitors, fibrinolytic factors and platelet membrane receptors.
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Is the reduction in respiratory amplitude an effect of vagal inhibitory feedback from lung stretch?
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Then we used filter theory to explain the difference between X and Y cell's spatial property and discussed effect of the large disinhibitory area on the spatial property of classical receptive field.
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Several nucleoside-based inhibitors of these viral enzymes, including that of the HIV virus, also typically show modest inhibition of telomere synthesis.
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Twenty-four hours after treatment, leaves were ground with a mortar and the expressed leaf extract was analyzed for proteinase inhibitor concentrations by radial immunodiffusion as described previously.
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Most popular sliced brands have preservatives and mould inhibitors such as calcium propionate and ascorbic acid.
The Sun
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In order to start the clinical phases for the HIV fusion inhibitors compounds, the company requires a technological partner with expertise in galenic peptide.
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Supraoptimal concentrations were inhibitory, probably because of the excessive osmolarity of the incubation medium.
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The carbanion intermediate analog, 2-hydroxy, 3-nitropropionate is competitive with respect to both malate and fumarate and therefore represents the intermediate species in the recycling whereas all other inhibitors are competitive with only one or the other of the substrates and therefore represent product species.
Irwin Rose - Autobiography
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A phosphatase inhibitor, sodium vanadate, reduced the effect of alkaline phosphatase and the p48 band remained undetectable.
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It is therefore not unreasonable to propose that bile salts might be the inhibitory component in the venous effluent.
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There are two classes of drugs to reduce uric acid: uricosurics, such as probenecid, which increases excretion, and xanthine oxidase inhibitors, such as allopurinol, which reduce production.
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There are two main types of preservatives: those containing an acid, such as propionic, acetic, and formic acids, and those containing mold inhibitors.
Fort Frances Times Online -
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Those studies found that the protein encoded by the Ciona AOX gene made its way to mitochondria, where it conferred cyanide-resistant respiration and protected against metabolic acidosis, oxidative stress, and cell death when cells were treated with OXPHOS inhibitors such as antimycin or cyanide.
Health News from Medical News Today
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Alkaline cleaning is used to remove oils, inhibitors, lubricants and dirt prior to coating.
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Available cholinesterase inhibitors drugs are donepezil, galantamine, rivastigmine, and tacrine. antipsychotic agents (olanzapine, quetiapine, risperidone), were found to have "adverse effects offset advantages in the efficacy of atypical antipsychotic drugs for the treatment of psychosis, aggression, or agitation in patients with Alzheimer's disease.
Citizendium, the Citizens' Compendium - Recent changes [en]
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This tonic contraction is mostly myogenic, due to special properties of this smooth muscle, but it is modified by excitatory and inhibitory nerves.
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The suspect compounds, known as cholinesterase inhibitors, aren't normally toxic at low levels.
Poisoned In The Gulf?
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The majority of chemotherapeutic strategies have, therefore, focused on the development of retroviral enzyme inhibitors.
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The inhibitory effect of the GABA/benzodiazepine complex on neuronal discharge produces sedation, anticonvulsant activity, anxiolysis and striated muscle relaxation. 6,7,8,9
Flumanazil
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Apart from monoclonal antibodies, small molecule therapeutics such as oncogenic protein kinase inhibitors are attracting a vast amount of investigational attention.
Ebookshare
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The existence of nitrate had an inhibitory effect on p-NCB reduction because of competition for electron donor between nitrate and p-NCB.
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It is also an effective antagonist or inhibitor of cortisol, a stress hormone that maintains the integrity of the circulatory system.
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Barium sulfonate and barium soap of petroleum ester oxide were dissolved in kerosene or machine oil to prepare oil-soluble corrosion inhibitor.
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The inhibitory stabilization of the membrane might be pictured as a heightening of the "resting" polarization, somewhat on the lines of an electrotonus.
Sir Charles Sherrington - Nobel Lecture
