How To Use Immune response In A Sentence
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Flying consumes a great deal of energy, and so, we reasoned, the energy demands of flying would compete with the energy needed to fuel the immune response.
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The results showed that the women in unhappy relationships and the women who remained emotionally hung up on their ex-husbands had decidedly weaker immune responses than the women who were in happier relationships (or were happily out of them).
Is There a Health Advantage to Being Married? | Impact Lab
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In the absence of a normal cellular immune response, bacterial proliferation may lead to infection.
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Hyperimmune responses, either at the initial immunisation challenge or in the amplification of immune response, can be observed in cellular mechanisms such as basophil degranulation, or at a molecular level, with changes in the levels of messengers such as leukotrienes; reduction of the intensity of these mechanisms are described in terms of molecular pharmacology, such as selective or nonselective inhibition of lipoxygenases.
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Pre-clinical data from earlier studies indicated significantly enhanced immune responses against the malaria parasite (circumsporozoite stage of the Plasmodium falciparum) when Crucell's AdVac� technology and GSK's RTS, S/AS technology are used in combination, versus either component alone.
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Hines MT, Palmer GH, Knowles DP, Alperin DC, et al. (2003) Analysis of anamnestic immune responses in adult horses and priming in neonates induced by a DNA vaccine expressing the
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You have an immune response to the vaccine as your body develops antibodies to the virus.
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An adjuvant is a vaccine component that boosts the immune response to the vaccine.
Aluminum
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The reason: The vitamin is involved in raising a healthy immune response.
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the immune response recognizes invading substances
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In the realm of immunology, substances that cause immune responses or allergic reactions are known as antigens.
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New therapeutic strategies are now urgently needed to reinforce anticancer immune responses and to complement existing treatments.
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HLAs, or human leukocyte antigens, are molecules involved in the immune response.
Priya Malhotra: Sex With Neanderthals: The Ultimate Immunity Boost
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Significant numbers of larvae reach the lungs and migrate to the bronchioles where they are killed by the animal's immune response.
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And if opponents aren't used to seeing such naked aggression, until they do, their immune response will be somewhat impaired.
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The body uses humoral and cellular immune responses to reject a transplanted graft.
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HIV is a progressive disease which the immune response ultimately fails to control.
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Pre-clinical data from earlier studies indicated significantly enhanced immune responses against the malaria parasite (circumsporozoite stage of the Plasmodium falciparum) when Crucell's Adenovirus (AdVac®) technology and GSK's RTS, S/AS technology are used in combination, versus either component alone.
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This rapid platelet decrease suggests an anamnestic response (i.e. a rapid immune response to new antigens by an already primed immune system).
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Because histoplasmosis can mount an immune response, skin tests are often done.
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Biological Therapy, or immunotherapy, uses substances made naturally in the body to stimulate or bolster your own immune response to the disorder.
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In the presence of a competent immune response the parasite encysts.
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Thus a balance of forces can result from a weakened infection which induces a weakened immune response,(sentence dictionary) leading to persistence.
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Thus, there is some suggestion of variation in the immune response within Crohn's disease.
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The immune response produces a syndrome of inflammation at the site of the infection.
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This hypothesis needs to be tested by using long acting and short acting antimalarials and studying their effect on immune responses.
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Antibodies acquired through colostrum at birth are critical to the newborn's health, but only last three to six months and while present can block the immune response to a vaccine.
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Women with higher levels of perceived stress were more likely an impaired immune response to HPV 16.
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Duncan BW, Harrison MR, Flake AW, Bethel CI, Bigler ME, Roncorolo MG: Immune response in hematopoietic chimeric rhesus monkeys.
Fetal Stem Cell Transplantation, In Utero Stemm Cell Publications
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However, the primary cause of Crohn's disease is thought to be a dysregulated immune response to gut bacteria.
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New TB adjuvants (enhancers of the immune response) have been studied.
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If we find that giving the vaccine intradermally is safe and prompts an immune response that is as strong as when the vaccine is given subcutaneously, we potentially could protect more people with the same amount of vaccine," said Dr. Sharon Frey, principal investigator and professor of infectious diseases at Saint Louis University School of Medicine, in a statement.
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Rubin also strongly urges all dieters not to do any aerobic exercise, as it harms the body's immune response.
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Using Crucell's AdVac® technology with two different adenovirus vectors - Ad35 and Ad26 - as delivery mechanisms, this approach seeks to elicit a protective immune response obtained from delivering the circumsporozoite protein (CSP).
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Furthermore, immune responses to tubercle bacilli are extraordinarily complicated.
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This cell population, termed multipotent progenitor cells, or MPP, appears to be activated in the context of allergies or infection with parasitic worms and may be one of the earliest cellular events in the developing immune response.
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Schistosoma mansoni (a platyhelminth) [17] Phylogenetic comparisons of putative Hirudo innate immune response genes present within the Hirudo transcriptome database herein described show a strong resemblance to the corresponding mammalian genes, indicating that this important physiological response may have older origins than what has been previously proposed.
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H2 immune responses, with specific "allergenic" potential (thus the "Asp f" designations).
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With cellular immune response, specific cytotoxic T cells are formed.
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The term adjuvant, from a Latin word meaning "to help," was coined in the 1920s by Gaston Ramon, a veterinarian at the Pasteur Institute in France, who observed that horses given diphtheria toxin had a stronger immune response if they had some inflammation at the injection site.
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The viruses being tested induce an immune response for which pre-clinical tests with immunodeficient mice can't wholly account.
The Scientist
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It is possible, however, that synthetic chemicals might affect the immune response in some way.
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In a number of laboratory and clinical trials, dendritic cell immunotherapy had succeeded in eliciting a powerful immune response against brain tumor cells, but significant improvements in length of survival had not been realized.
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In the acutely infected child or adult, this stage represents the incubation period before immune response.
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In a recent study, it was determined that cellular components of the body's natural immune system (such as monocytes and granulocytes) bound Viscum album agglutinin-I molecules to a higher degree than lymphocytes, suggesting that this herb can support natural immune responses.
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The role played by histamine as an immunomodulator and the obvious involvement of spleen cells in the immune response of the organism prospect new scenarios in which NGF may gain access, not through a back door, but through the main entrance.
Nobel Lecture The Nerve Growth Factor: Thirty-Five Years Later
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Through a series of steps called the immune response, the immune system attacks organisms and substances that invade our systems and cause disease.
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The vaccine, which generates an immune response to the parasite's circumsporozoite protein, is far from perfect.
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These flares may be caused by other viral infections, or they may be secondary to viral reactivation and an unregulated immune response.
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Although H pylori does not invade the mucosa, bacterial proteins may activate monocytes with a local T-cell mediated immune response.
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Leprosy is a complex mycobacterial disease whose manifestations and complications are determined by the immune response.
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HIV is a progressive disease which the immune response ultimately fails to control.
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In many cases of pathogen-induced immunopathology, the reduction or elimination of IL-10 activity should permit the desired effector immune response to eliminate with pathogen without further pathology.
FreshPatents.com: Notable Patent Applications - 07/22/2010
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HIV is a progressive disease which the immune response ultimately fails to control.
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We investigated condition dependence of secondary sexual characters and the immune response variables using residual body mass as an estimate of body condition.
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The use of immunoassays that detect antibodies that bind to epitopes on the bacterial surface of the homologous infecting strain is important to detect potentially protective immune responses.
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In our comparative study of immune response after vaccination with BCG, in subjects from Chengalput, India and London, M. bovis BCG vaccination did not enhance bacteriostasis with the Indians, but did so with the subjects from London.
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Intraperitoneal injection of xenogeneic cells resulted in the development of an immune response as tested by ELISA.
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It has been said the butter may reduce the risk of cancer because it contains healthy bacteria which aids digestion and boosts immune response.
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Other molecules, the happens, also generate an immune response.
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This immune response leads to the destruction of the beta cells that make insulin.
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The suppression of immune responses is costly, in particular for nonresistant individuals with high levels of somatic infections.
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Antimalarial drugs or immune response modifiers like methotrexate can reduce steroid dose and side effects.
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Furthermore, immune responses to tubercle bacilli are extraordinarily complicated.
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They also studied structures called microglia, which activate the brain's immune response.
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According to this theory, an initial insult caused by an infective agent, drugs, or gluten may damage mucosal surface, leading to an autoimmune response with ongoing inflammation in susceptible individuals.
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This overnutrition is a threat to our survival and it stimulates an innate immune response because that's the only response we have.
Inflammation and diet | The Blog of Michael R. Eades, M.D.
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The authors noted a marked augmentation in immune response demonstrated by a change from complete anergy to normal immune response in one patient.
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The role of B-cells in the immune response is to release antibodies that may opsonize a particular cell and assist T-cells in destruction of that cell.
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HBV is not cytopathic, and liver injury is caused by the host's immune response against infected hepatocytes.
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Now, the term eczema usually refers to atopic eczema, or atopic dermatitis (atopic means “allergic”), which is a complex genetic disorder that results in defective skin barriers, reduced innate skin immune responses, and exaggerated immune (T cell) responses to environmental allergens that lead to chronic skin inflammation.
You Raising Your Child
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The reason: The vitamin is involved in raising a healthy immune response.
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With disease progression, the autoimmune response of the disease may become more difficult to suppress.
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Their results indicate that the cellular immune responses needed to protect against TB and HIV, are impaired by ascariasis and other helminthic infections.
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Traditional vaxes must be kept cold and don't always trigger a sufficient immune response.
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Biotherapy is designed to repair, stimulate, or enhance your bodys own immune responses.
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Objective To compare humoral immune responses and T helper cell polarization induced by different injection methods of a multi epitope chimeric DNA vaccine.
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Additionally, the grafts also contain minor histocompatibility antigens, which will elicit a rather slow immune response.
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Infection with T gondii induces both cellular and humoral immune responses.
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Candidate antisepsis therapies have included agents that target host cell activation, mediators of the inflammatory response, agents that boost the immune response, and prostaglandin inhibitors.
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Discussion Coeliac disease probably represents an aberrant immune response by antigen specific T cells of the small intestine to certain cereal peptides.
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The article warns that the immune response to pre-exposure vaccination may be impaired by concurrent use of antimalarial drugs.
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The molecule delivers proteins to a crucial cluster of genes and helps regulate immune response, cancer growth, and fat and stem-cell production, among other things.
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Those who are untroubled by the norms of society suffer from much lower levels of stress, so their immune response systems function more efficiently.
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Cellular immune responses in higher eukaryotes entail specific acts of cell proliferation and differentiation.
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Hence the delay between the onset of flu and the immune response that cures it.
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Although the largest post-mating increase occurred in immune response genes, one antimicrobial peptide, cecropin, is secreted in what appears to be a plug protecting the entrance to the oviduct.
Proceedings of the National Academy of Sciences current issue
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Biopharmaceutical company Novavax jumped 25 cents, or 11%, to 2.59 after the first stage of a trial studying the Rockville, Md., company's pandemic influenza vaccine showed that safety and immunogenicity, or the ability to invoke an immune response, were consistent among the entire 1,000-person study population.
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Some squamate reptiles appear to have relatively slow cellular immune responses compared with mammals.
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With the development of a protective immune response and serological evidence of immunity, infection becomes latent and usually remains so for the life of the patient.
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Both humoral and cellular immune responses are important in clearing the parasite and providing immunity.
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The result demonstrated that Rhesus monkey immunized by multi epitope PCX could elicit high - level immune responses.
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This immune response leads to the destruction of the beta cells that make insulin.
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The drug then reinvigorates patients' anti-tumour immune response and promotes shrinkage of the tumour.
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While antigene composition of human and animals tissues is different, some overlapping exists, so autoimmune response against brain tissue of vaccinated children is possible.
On Thursday, the Legg report will be published along with...
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In the realm of immunology, substances that cause immune responses or allergic reactions are known as antigens.
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To study the effects of a primary immune response to T-cell dependent antigens on central serotonin(-HT)metabolism, keyhole limpet hemocyanin(KLH)was administered intraperitoneally to F male rats.
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Rejection is the term applied to the natural immune response to foreign tissue.
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Its primary way of killing cancer cells is by eliciting an immune response, drawing what are known as effector cells (various types of killer white blood cells) to the tumor and activating them.
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A previous kidney biopsy from New Hampshire had shown membranoproliferative glomerulonephritis, inflammation of microscopic structures in the kidney caused by an abnormal immune response.
After the Diagnosis
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Therefore, they may fail to elicit a humoral immune response.
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Another reason for multiple doses is that immune responses last longer after more than one dose of some vaccines.
Vaccine Schedules
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The products use a large amount of organisms and adjuvants such as aluminum hydroxide or oil to produce a sufficient immune response.
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the specific target of the immune response in rheumatoid arthritis is filaggrin
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Detection of IgG isotype reactivity with the E7 oncoproteins of HPV appears to reflect the effectiveness of the immune response against cervical cancers and their precursors.
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We have previously postulated that the amplification and divergence of the members of the mucin family covering the trypanosomal surface are also involved in delay the host immune response
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Plants produce phytoalexins as an immune response to physical, chemical, or biological damage.
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Many components of ESA have potent immunogenicity, and induce protective cell - mediated and humoral immune responses.
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Adjuvants enhance the immune response by increasing the stability of the vaccine in the body, which then stimulates the immune system for a longer time.
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Administration of cytokines or cytokine antagonists alters only one aspect of a complex immune response.
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The results indicated that the level of cellular and humoral immune response of probiotical chicks after immunizing with ND vaccine could be enhanced .
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Progressive growth of a spontaneous T cell lymphoma, designated as Dalton's lymphoma, causes suppression of immune responses and thymic atrophy.
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HIV is a progressive disease which the immune response ultimately fails to control.
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Figure 3 is a schematic illustration of the suggested mechanisms responsible for eliciting an immune response resulting in acquired hemophilia.
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Natural silk contains the glycoprotein sericin, which causes an immune response when used in medical sutures.
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The drug then reinvigorates patients' anti-tumour immune response and promotes shrinkage of the tumour.
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Autoimmune responses are believed to play a prominent role in polymyalgia rheumatica, with bursitis, synovitis and tenosynovitis of the proximal shoulder and hip girdles being characteristic features.
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As an important leucoprotease, myeloperoxidase (MPO) has many effects in mediating inflammation, regulating immune response and so on, which also takes part in the genesis and development of diseases.
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It is clear that a significant proportion of heterogeneity in outcome of infectious disease can be attributed to deviation of the immune response in one direction or the other.
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The DC were also exposed to keyhole limpet hemocyanin (KLH), which was used as a surrogate marker to show an immune response.
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The similarity between an allergic response and an autoimmune response is clearest in the autoimmune disease known as celiac disease—what some term a gluten allergy—in which the body perceives gluten as a foreign invader.
The Autoimmune Epidemic
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Likewise, the suppression of the cellular immune response can be determined using well known in vitro analyses, e.g., proliferation and cytotoxicity assays or characterization of activation phenotypes of peripheral blood lymphocytes by, e.g., flow cytometric analysis.
FreshPatents.com: Notable Patent Applications - 07/22/2010
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Studies have shown that it can enhance both the innate immune response to fight infections as well as adaptive immune response conferring long-term immune enhancement.
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When inoculated into humans, the weakened bacteria should induce an immune response but not cause disease.
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It is known which specific immune responses are required for therapeutic benefit, so we have proceeded cautiously.
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Many of us believe the human body contains an immune system which we evolved to fight off disease, and rather than introduce harmful toxins (that's exactly what a vaccine adjuvant is – its the intended purpose, to be toxic and elicit an immune response to make the vaccine effective), we're willing to take the chance that we might get the flu, and in almost all cases, that means a couple days off work feeling crappy.
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Still working with teratocarcinoma, he once again stumbled onto a remarkable aspect of the immune response to cancer.
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Infection is oral, and the virus multiplies in the pharynx and intestine for one to three weeks before it is contained by a local immune response or a viraemic phase occurs.
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The degree of completeness of the combinatorial system in the most anciently arisen living vertebrates to possess the combinatorial immune response was surprising.
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In the virino model, the host protein protects the scrapie agent nucleic acid from degradation and prevents the host raising an immune response, since the protein/nucleic acid complex is seen as ‘self’.
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An immune response is brought about by two components of the immune system, namely the innate immunity and the acquired or specific immunity, acting in conjunction with each other and with other molecules.
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The researchers used weakened versions of two viruses commonly used in vaccine development -- a common cold virus called an adenovirus and a smallpox virus -- to deliver the primate version of the HIV antigen into the body and trigger an immune response.
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In preclinical trials, it has been shown to reduce the incidence of diabetes in animals, apparently by down-regulating the immune response.
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This immune response elevates the level of a blood antibody known as IgE.
The Autoimmune Epidemic
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This novel vaccine induces strong cellular and antibody immune responses in animal models, including non-human primates.
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Even though HBV is not considered a cytopathic virus, immune responses directed against HBV epitopes will continue to cause hepatic damage in the presence of viraemia.
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Augmentation of immune responses to the disease with dendritic cells and idiotype vaccination is also being evaluated.
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However, no significant covariation was observed between length of the tarsometatarsus, an index of skeletal body size, or intensity of T-cell-mediated immune response and sonographic features of begging calls.
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As before, treatment of nonirradiated mice with active or inactive T4N5 had no effect on the generation of an immune response.
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Purpose To observe an immune response to acupoint injection of pertussis vaccine.
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These gene products control innate immune responses and further instruct development of antigen-specific acquired immunity.
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Domenech P, Manca C, Su H, Barczak AK, et al. (2004) A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response.
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Although H pylori does not invade the mucosa, bacterial proteins may activate monocytes with a local T-cell mediated immune response.
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The results confirm the association with protection of anti-MSP3 cytophilic responses, confirm in one additional setting that worms increase malaria morbidity and show a Th2 worm-driven pattern of anti-malarial immune responses.
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Still working with teratocarcinoma, he once again stumbled onto a remarkable aspect of the immune response to cancer.
Vaccinating Against Cancer
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Because these islets carried the kind of peptide that spleen cells use to reeducate the immune system, they were able both to control blood sugar and to end the autoimmune response.
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Immunonutrients have been shown to upregulate host immune response, to control inflammatory response, and to modulate nitrogen balance and protein synthesis after injury.
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An altered immune response to Epstein-Barr nuclear antigen 1 in pediatric systemic lupus erythematosus.
The Autoimmune Epidemic
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Dr. Benacerraf's specific contribution was the discovery that the strength of an individual's immune response was controlled by a group of genes, which he called "immune response genes.
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Conclusion Hepatitis A vaccine with attenuated Salmonella typhimurium as vector can induce immune response.
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For a study of female immunological infertility by Chen Xiaoping, researchers used Guyin Decoction ginseng, rehmannia, dioscorea, cornus, cuscuta, polygala, schizandra, and licorice to treat 60 women with infertility attributed to antisperm immune response.
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Early risk may suggest a mechanism involving an aberrant immune response to cereal antigens in an immature gut.
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Conversely, an allergy is a hyperimmune response to a special antigen called an allergen (eg, pollen, chemical substances).
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The researchers hypothesize that the pronounced loss of these neurons could be caused either by a neurodegenerative process or an autoimmune response.
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This alteration is thought to be mostly the result of the immune response to the virus.
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These cells have the potential to present tumour-specific antigens and thereby induce an immune response.
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The result was azathioprine (1957) which replaced mercaptopurine as an inhibitor of the immune response.
Physiology or Medicine 1988 - Press Release
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But, for people with gluten intolerance, or celiac sprue, the body perceives gluten as a foreign substance and responds with a full-blown immune response.
