How To Use Homeobox In A Sentence
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Homeobox genes encode transcription factors involved in many aspects of developmental processes.
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Black vertical lines indicate the typical homeobox gene family and gray vertical lines the atypical homeobox gene family.
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Homeobox gene is a sort of regulatory gene which controls embryonic development and cellular differentiation.
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This binding capability can be pinpointed to a characteristic base sequence known as a homeobox.
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Comparisons of the roles of homeobox genes in metazoan development are playing a pivotal role in the current resynthesis of developmental and evolutionary biology.
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As an evolutionary biologist, I would assert that the modification of the ancestral homeobox function (i.e. longitudinal differentiation) into the regulation of longitudinal metameric development would qualify as an example of evolutionary exaptation, which Stephen Jay Gould emphasized as one of the principle mechanisms of macroevolution.
Ancient Predator Revealed!
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Homeobox genes play a key role in the morphogenesis of segmental body structures along the primary anterior-posterior body axis including the genitourinary system.
Urology Division Research
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A homeobox gene involved in setting up the mammalian body plan also appears to control grooming behavior in mice.
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If it turns out that there are other possible mechanisms but that the homeobox regulatory mechanism was the least costly evolutionary speaking for primitive animals with out metamerism then MET gains additional plausibility
Ancient Predator Revealed!
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If I were a FLID supporter, I would propose that the homeobox regulatory mechanism for body regions was a "front-loaded design element" that, once it was in place, could be modified extensively via standard evolutionary mechanisms to produce the various metameric metazoan bauplans.
Ancient Predator Revealed!
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In the context of this thread, the homeobox regulatory mechanism of non-metameric ancestral metazoans (such as flatworms) would qualify as an exaptation for the homeobox regulatory mechanism of their metameric descendants.
Ancient Predator Revealed!
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Few, for instance, are found near the critical regions known as homeobox gene clusters.
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Sean Carroll's book, Endless Forms Most Beautiful has a good, relatively simple description of how the homeobox regulatory mechanism is tied to metamerism.
Ancient Predator Revealed!
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Because of their fundamental importance in development, homeobox genes are of substantial interest to evolutionary biologists as they may provide key information on the evolution of development.
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LIM homeobox gene family is one of the several subfamilies of homeobox genes.
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In Gould's concept of the term, the original homeobox regulatory mechanism would have evolved first in non-metameric animals, and then become modified later in the dominant metameric forms (i.e. arthropods and vertebrates).
Ancient Predator Revealed!
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He and his group have discovered the homeobox, a DNA segment characteristic for homeotic genes which is not only present in arthropods and their ancestors, but also in vertebrates up to man.
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A gene can only be called a Hox gene sensu stricto if it has a homeobox sequence, is homologous to other known Hox genes, and is organized in a colinear cluster.
Jellyfish lack true Hox genes! - The Panda's Thumb
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Miller DJ (1992) Genomes of diploblastic organisms contain homeoboxes: sequence of eveC, an even-skipped homologue from the cnidarian Acropora formosa.
PLoS ONE Alerts: New Articles
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This binding capability can be pinpointed to a characteristic base sequence known as a homeobox.
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If I were a FLID supporter, I would propose that the homeobox regulatory mechanism for body regions was a "front-loaded design element" that, once it was in place, could be modified extensively via standard evolutionary mechanisms to produce the various metameric metazoan bauplans.
Ancient Predator Revealed!
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Lapebie P, Renard E, Bezac C, Boury-Esnault N, et al. (2008) NK homeobox genes with choanocyte-specific expression in homoscleromorph sponges.
PLoS ONE Alerts: New Articles
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So, would the homeobox regulation of metamerism be considered as a "front-loaded" pre-adaptation?
Ancient Predator Revealed!
