How To Use Heterozygous In A Sentence
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In heterozygous females, pre-B cells whose active X chromosome expresses the mutant gene would not terminally differentiate and proliferate.
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We sequenced genomic DNA from heterozygous animals in an attempt to identify the remaining mutations.
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In practice this model could be extended to include inferences from crosses with resulting heterozygous individuals, such as backcrosses or intercrosses.
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CRANE: In the first place, the chromosomes are so small and there are so many, that you can't identify them, and you can't tell which genes, and they have got a heterozygous population, and the variety is self-sterile and has to be cross-pollinated, so there is only one way from a horticultural standpoint by which we can do anything, and that is through clones.
Northern Nut Growers Association Report of the Proceedings at the 41st Annual Meeting Pleasant Valley, New York, August 28, 29 and 30, 1950
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An allele does not care if it is in a half - blooded ( heterozygous ) or pure - blooded ( homozygous ) individual.
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When an organism is heterozygous for a trait, the resulting phenotype for that trait expresses only the dominant allele .
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heterozygous for eye color
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Ten wild-type females crossed with mutant males gave birth to 22 heterozygous mutant mouse pups and 30 wild-type littermates, which were used as control pups.
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The mutation was heterozygous and replacing a highly conserved Asn residue with a Ser.
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Animals developed as perfectly normal hermaphrodites if derived from a heterozygous hermaphrodite mother.
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Heterozygous mutations in the gene encoding the CHD (chromodomain helicase DNA-binding domain) member CHD7, an ATP-dependent chromatin remodeller homologous to the
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‘Heterozygous’ means having two different allelomorphs in the two corresponding loci of a pair of chromosomes.
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Amplification with both normal and mutant primers indicates the heterozygous deletion of that type.
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Recombination requires the simultaneous infection of a cell with two different proviruses, allowing the encapsulation of one RNA transcript from each provirus into a heterozygous virion.
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These mutants were also included in a project that examined the distribution of aborted seeds in heterozygous siliques as a measure of gametophytic expression of emb64) was identified from a collection of X-irradiated seeds generated in the 1980s by Joseph Ecker
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Results We identified and validated compound, heterozygous, causative alleles in SH3TC2 (the SH3 domain and tetratricopeptide repeats 2 gene), involving two mutations, in the proband and in family members affected by Charcot-Marie-Tooth disease.
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Among their findings, mice heterozygous for a null mutation of the alpha-isoform of calcium / calmodulin-dependent protein kinase II show profoundly dysregulated behaviors, including a severe working memory deficit and an exaggerated infradian rhythm (cycle of increases and decreases in locomotor activity in their home cage; 2-3 weeks / cycle), which are comparable to the symptoms observed in patients with schizophrenia, bipolar disorder and other psychiatric disorders.
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In the higher liability classes the probability of an affected individual being heterozygous or homozygous for the major allele was about 0.10.
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Conclusion The proband's hearing loss resulted from the compound heterozygous mutations N392Y and S448X for SLC26A4 gene.
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Both heterozygous Cx 43 KO and CMV 43~ CT transgenic mice had normal hearts.
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What is the expected genotypic ration resulting from a homozygous dominant x heterozygous monohybrid cross? what are some examples of generalists (species with broad niches) and specialist (species with narrow niches)?
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Because SHARP studied the combination of simvastatin and ezetimibe compared with placebo, it was not designed to assess the independent contributions of each drug to the observed effect; for this reason, the FDA did not approve a new indication for VYTORIN or for ZETIA ® (ezetimibe) and the study's efficacy results have not been incorporated into the label for ZETIA.VYTORIN is indicated as adjunctive therapy to diet for the reduction of total cholesterol, LDL cholesterol, apolipoprotein B, triglycerides, and non-HDL cholesterol, and to increase HDL cholesterol in patients with primary (heterozygous familial and nonfamilial) hyperlipidemia or mixed hyperlipidemia when diet alone is not enough.
Forbes.com: News
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A resulting triple-heterozygous resistant-susceptible plant, i.e., a heterozygous plant at the three resistance loci, was isolated and selfed to produce the 27 expected genotypes described in Table 1.
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It was shown that most mutant genes are incompletely recessive (not «overdominant») and are acted upon by selection while heterozygous.
Hermann J. Muller - Biography
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When an organism is heterozygous for a trait, the resulting phenotype for that trait expresses only the dominant allele .
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Our findings provide the first example of a single overdominant gene for yield and suggest that single heterozygous mutations may improve productivity in other agricultural organisms.
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The rationale is that self-sterile ryes are highly heterozygous and commonly carry deleterious genes (in heterozygous condition), some of which become homozygous in triticale and presumably result in reduced vigor and/or fertility.
8 Research Needs
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It had been known for some time that a crossover within the inverted segment in plants that are heterozygous for an inversion in one arm of a chromosome would result in a dicentric chromosome, and also an acentric fragment composed of all the chromatin from the distal breakpoint of the inversion to the end of the arm.
Nobel Lecture The Significance of Responses of the Genome to Challenge
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An example of overdominance is the allele in black Africans that confers resistance to malaria when present in one chromosome (heterozygous), but causes sickle cell anemia when present in both (homozygous).
"The more we play God or try to improve on Mother Nature, the more damage we are doing with all kinds of experiments that... turn into nightmares."
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Developmentally early induction often yields no clones at all, suggesting that the small clones depend on perdurance of wild-type gene product from the heterozygous clone precursor cell.
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One such condition includes homozygous familial hypercholesterolemia, which is rarer than the heterozygous form.
The Seattle Times
