Get Free Checker

How To Use Gene expression In A Sentence

  • These results illustrate that variation exists in maize for the impact of ploidy on gene expression.
  • Kantorow M, Kays T, Horwitz J, Huang Q, Sun J, et al. (1998) Differential display detects altered gene expression between cataractous and normal human lenses. PLoS ONE Alerts: New Articles
  • The highest GOX expression levels (1552 units of secreted protein per gram dry cell weight) were achieved with the strain K. marxianus CBS 6556, using an episomal system in which the INU1 promoter and terminator were used to drive heterologous gene expression, together with the INU1 prepro sequence, which was employed to drive secretion of the enzyme. BioMed Central - Latest articles
  • The next decade will better characterize how the environment affects gene expression--the genome-exposome interactions--and our health, and provide us better ways to measure and improve those interactions and help us create the best expression of ourselves. Mark Hyman, MD: Why Your Genes Don't Determine Your Health
  • This process is commonly manifested in chromosomal monosomics in which the most common effect is an approximate twofold increase of target gene expression throughout the genome.
Master English with Ease
Translate words instantly and build your vocabulary every day.
Boost Your
Learning
Master English with Ease
  • So imprinting of X-linked genes naturally results in sexually dimorphic gene expression.
  • Methods Osteoblast related gene expression frequency, specialty, and the relationship between osteoblastic phenotype and biological behavior of osteosarcoma were studied.
  • In recent years, studies searching for association between genetic markers and quantitative gene expression profiling, referred to as genetical genomics PLoS ONE Alerts: New Articles
  • This leads me to speculate that behavioral state-related gene expression may be of essence in exploring the deep psychobiology of consciousness in therapeutic hypnosis.
  • Objective To delineate the immune regulatory pathway in pathogenesis of systemic lupus erythematosus (SLE) by using gene expression profile analysis.
  • These biochemical and organismal effects are evolutionarily dissociable to some extent, because some changes in gene expression appear to have no consequence for organismal phenotype.
  • As a next step, he intends to build more-complex nanorods that will yield higher and more-sustained rates of gene expression, which would be necessary to treat diseases such as hemophilia and cystic fibrosis.
  • I can make antisense RNA and block the gene expression -'`Hold it. VITALS
  • Conversely, in other regions such as the hippocampus and olfactory bulb, which is associated with smell, gene expression was more contained.
  • As a next step, he intends to build more-complex nanorods that will yield higher and more-sustained rates of gene expression, which would be necessary to treat diseases such as hemophilia and cystic fibrosis.
  • It is, in principle, possible that sphingosine could be involved in the regulation of gene expression and signal transduction.
  • Hence the authors concluded that gene expression had diverged most rapidly in the human brain.
  • Guess what, gene expression produces the same nested hierarchy of relatedness, with chimps our closest relatives, as we find for genes.
  • Cross species comparison reveals a strong variability of gene expression along the oral-aboral axis and during the life cycle among cnidarian lineages. PLoS ONE Alerts: New Articles
  • However, even this correlative approach does not necessarily demonstrate the underlying mechanism, especially given the diversity of changes in gene expression, and the likely multi-component nature of resistance.
  • The bactericidal agent triclosan modulates thyroid hormone-associated gene expression and disrupts postembryonic anuran development. WHAT REALLY HAPPENED
  • Given the complexity of gene expression prenatally and postnatally, variation by racial or ethnic admixture may or may not occur. Dan Agin: Black and White in America IV: IQ Myths and Realities
  • Research trauma state of mononuclear cell gene expression: a serious trauma often leads to fatal sepsis and toxic shock.
  • It appears that the purine metabolic system in humans has found a way to avoid the overproduction of uric acid by downregulating the Xor gene expression, the product converting hypoxanthine to xanthine and further xanthine to uric acid.
  • These ubiquitous probes have been extremely useful as reporters for gene expression studies in cultured cells and tissues, as well as living animals. Archive 2005-10-01
  • The gene expression biomarkers of caloric restriction can also be used to develop pharmaceuticals targeted to its genomic effects.
  • The positive clinical results, together with our previously published mechanisms of gene expression modulation related to key metabolic pathways in lipid metabolism, provide impetus for much larger clinical studies. Meat and mortality | The Blog of Michael R. Eades, M.D.
  • There is indeed direct evidence that mechanical stress can generate intracellular signals that regulate gene expression.
  • The essential and initial problem of gene expression microarray data analysis is to identify differentially expressed genes (DEGs), under certain conditions.
  • As discussed in chapter 2, the flavor cinnamic aldehyde contains Michael acceptor pharmacophores, which turn on gene expression of a number of cell-protective antioxidant enzymes. Forever Young
  • Flores-Morales A, Stahlberg N, Tollet-Egnell P, Lundeberg J, Malek RL, et al. (2001) Microarray analysis of the in vivo effects of hypophysectomy and growth hormone treatment on gene expression in the rat. PLoS ONE Alerts: New Articles
  • This distribution of gene expression suggests that different micro-environments exist within the granulomas, to which the bacilli are responsive, adopting different metabolic states.
  • They also recorded gene expression in real - time using a bioluminescent reporter of gene activity.
  • In this study, the pectate lyase gene expression was located in the recent products of cambial divisions of both phloem and xylem and conspicuously localized in the xylem parenchyma cells of young vascular bundles.
  • Genetic epistasis of gene expression can also be considered with large sample sizes.
  • Weickert CS, Straub RE, McClintock BW, Matsumoto M, Hashimoto R, et al. (2004) Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain. PLoS ONE Alerts: New Articles
  • DNA microarray has been applied to DNA sequencing, pharmaceuticals analysis, gene expression and so on.
  • N, et al. (2008) Visual sensitivities tuned by heterochronic shifts in opsin gene expression. PLoS Biology: New Articles
  • There is indeed direct evidence that mechanical stress can generate intracellular signals that regulate gene expression.
  • It has also been fundamental in investigating many nonhereditary traits, especially gene expression relevant to complex diseases such as laminitis, developmental bone diseases, and colic.
  • Conclusion Disturbance of embryonic cell behavior and related gene expression played important roles in developmental toxicity caused by methylmercury.
  • It can regulate specific gene expression, cellular secretion and membrane permeability.
  • Although GVG-regulated gene expression has been characterized extensively in dicotyledonous and monocotyledonous plants such as tobacco, Arabidopsis, and rice, it has not been tested in gymnosperms.
  • Intriguingly, a different pattern of gene expression is seen when elongation in the presence of oxygen is promoted by ethylene or carbon dioxide.
  • The definition of epigenetics is somewhat variable, with some scientists limiting the term to refer to specific molecular mechanisms that alter gene expression.
  • In mung bean, mechanical strain, salt, cycloheximide, and auxin treatment could induce the CPK gene expression.
  • The definition of epigenetics is somewhat variable, with some scientists limiting the term to refer to specific molecular mechanisms that alter gene expression.
  • Over the past three decades a great deal of evidence has accumulated in favor of the hypothesis that steroid receptor hormones act via regulation of gene expression.
  • Similar effects on limb outgrowth and Hoxd gene expression were observed in forelimb cultures.
  • MicroRNAs, small RNA molecules that regulate gene expression, have been found to circulate in blood within lipid membrane-encased particles (exosomes) that are secreted from and blebbed off of cancer cells. Undefined
  • Extracts of diesel exhaust particles modulate the aryl hydrocarbon receptor and estrogen-dependent gene expression in cells in vitro and are endocrine disrupters.
  • Kilic E, Bahr M (2003) Human synapsin 1 gene promoter confers highly neuron-specific long-term transgene expression from an adenoviral vector in the adult rat brain depending on the transduced area. PLoS ONE Alerts: New Articles
  • Liu B, Fan Y, et al. (2007) Antisense RNA-mediated suppression of Bmi-1 gene expression inhibits the proliferation of lung cancer cell line A549. PLoS ONE Alerts: New Articles
  • Research trauma state of mononuclear cell gene expression: a serious trauma often leads to fatal sepsis and toxic shock.
  • By mapping homologous skeletal elements of the vertebrate forelimb onto their phylogeny, an explicit alternative interpretation of the significance of Hox gene expression emerges.
  • During latent infection, the viral genome persists as an episome, and viral gene expression is highly restricted.
  • The term epigenetics refers to heritable changes in gene expression and phenotype caused by mechanisms other than changes in DNA sequence. RedOrbit News - Technology
  • If so, my estimate of the total energy investment into gene expression will be an overestimate.
  • These cells are thought to resemble embryonic stem cells (ESCs) on the basis of global gene expression analyses; however, few studies have tested the ability and efficiency of iPS cells to contribute to chimaerism, colonization of germ tissues, and most importantly, germ-line transmission and live birth from iPS cells produced by tetraploid complementation. Naturejobs - All Jobs
  • It has been reported that ARF gene expression was not effected by auxin concentration.
  • We hypothesized that the highly efficient plasmid-based piggyBac transposon system would enable long-term inducible gene expression in mice in vivo. Naturejobs - All Jobs
  • Spontaneous SOS gene expression was measured in strain GY7109 recA carrying plasmids with different recAX chimeras.
  • Thus it appears that some aspects of ethylene-dependent gene expression are conserved between climacteric fruits such as melon and tomato.
  • However, temporal colinearity of Hox gene expression and compact Hox clusters have so far only been described in the cephalochordate, amphioxus, and in vertebrates, but not in Cnidaria, Lophotrochozoa, or Ecdysozoa.
  • The pattern of reporter gene expression exactly matches that of the trapped gene since its transcription starts from the promoter of this gene.
  • Frequency of successful exchange between taxa will depend on propinquity, metabolic compatibility, adaptations to their abiotic environment, gene expression systems, and gene transfer mechanisms.
  • Fetal intramuscular delivery of recombinant adenovirus results in persistent postnatal transgene expression in both muscle and liver. Fetal Gene Therapy Publications and Information
  • In lowly expressed genes, gene expression noise may cause a gene's expression level to dip below levels necessary for proper biological functions.
  • (F, lower level) densitometric analysis of gene expression plotted as the expression ratio to GAPDH, used as internal control. PLoS ONE Alerts: New Articles
  • To look at this they looked at changes in gene expression in an area of the brain called the striatum, which is an area associated with the rewarding and reinforcing properties of drugs like cocaine. ScienceBlogs Channel : Life Science
  • Although these features are inconsequential for the use of DsRed as a reporter of gene expression, the usefulness of DsRed as an epitope tag is severely limited. Archive 2005-10-01
  • The polymorphism at A-6G and G-217A sites in promotor region plays an important role in regulating the gene expression, and the products of keep close correlation with the level of blood pressure.
  • In addition to seeds, the promoters directed reporter gene expression in pollen and in seed coats.
  • An account of the development of behaviour within an individual would have to mention a series of environmental influences on gene expression.
  • Gene expression profiling in PPAR γ2-deficient cells indicated a major dysregulation of cell cycle control and metabolic signaling networks related to peroxisomal and lysosomal maturation, lipid oxidation and degradation. Naturejobs - All Jobs
  • LifeGen Technologies help validate the critical role gene expression modulation plays in the aging process. New Studies Show Significant Anti-Aging Benefits of Cordyceps - Yahoo! Finance
  • Diseases caused by aberrant gene expression include viral diseases and cancer.
  • The bactericidal agent triclosan modulates thyroid hormone-associated gene expression and disrupts postembryonic anuran development. WHAT REALLY HAPPENED
  • Promoter is an important cis-regulatory element for gene expression and plays an important role in the process of plant gene expression and regulation.
  • To investigate the importance of the nonadditive gene expression in relation to the additive gene expression, we investigated the potence for all genes with significant dominance effects.
  • Down-regulated topoisomerase II gene expression in etoposide-selected cells has also been shown to be associated with an increased rate of spontaneous polyploidization.
  • Despite its importance, relatively little is known about the structural determinants of beta-globin mRNA stability or how they contribute to regulating beta-globin gene expression. Sickle cell disease research at The Children's Hospital
  • Victor Oreffo (AstraZeneca, Loughborough, UK) presented results on gene expression analysis following in vivo or in vitro exposure to the oxidative stress agents menadione and diquat.
  • In addition, high-calcium diets inhibit lipogenesis, fat-producing gene expression, and accelerate lipolysis, the breakdown of stored fat. Fat is Not Your Fate
  • We propose that in Raji cells the accumulation of a repressor is prevented, thus allowing gene expression.
  • The promoter induced gene expression after heat shock in a time-course dependent manner.
  • Gene expression differences between highly malignant osteosarcoma and benign osteoblastoma involve cell cycle regulation. Naturejobs - All Jobs
  • Fetal intramuscular delivery of recombinant adenovirus results in persistent postnatal transgene expression in both muscle and liver. Fetal Gene Therapy Publications and Information
  • Smith J, Theodoris C, Davidson EH (2007) A gene regulatory network subcircuit drives a dynamic pattern of gene expression. PLoS Biology: New Articles
  • Epigenetic modifications, such as cytosine methylation, are inherited in plant species and may occur in response to biotic or abiotic stress, affecting gene expression without changing genome sequence. ScienceBlogs Channel : Life Science
  • Once NFκB is activated in the cytosol (watery portion of the cell) during oxidative stress (excess free radicals), it translocates to the nucleus, where it activates gene expression for the production of pro-inflammatory proteins called cytokines. Forever Young
  • All these processes are regulated by a complex intercellular communication regulating intracellular signal transduction and gene expression leading to an orchestrated re-epithelization of the skin as a whole. Naturejobs - All Jobs
  • There is indeed direct evidence that mechanical stress can generate intracellular signals that regulate gene expression.
  • Explants were incubated at different temperatures (°C) after bombardment and analysed for reporter-gene expression.
  • The more RNA segments that attach to a gene, the more that gene will glow or fluoresce, which is called gene expression.
  • Uniparental disomy and imprinting modify gene expression with passage through maternal or paternal meiosis.
  • The authors of the study published in Science noted a number of interesting things - a preponderance of genes encoding protein kinases, evidence for substantial horizontal gene flow from bacteria and archaebacteria, and a streamlined core gene expression machinery transcription and RNA processing. The Panda's Thumb: Research News Archives
  • If an impact is too rapid, and acclimation on the level of gene expression cannot occur, cellular damage and cell death are initiated.
  • While forelimb length is just one of several key morphological changes that occurred during the evolution of the bat wing, this unprecedented finding demonstrates that evolution can be driven by changes in the patterns of gene expression, rather than solely by changes in the genes, themselves. Ancient Sleep and Flipping Switches
  • In contrast to the extensive study of species with persistent endosperm, little is known about the global gene expression pattern in the endosperm of exalbuminous seed species such as crucifer oilseeds. BioMed Central - Latest articles
  • The term epigenetics refers to changes in the phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence. PhysOrg.com - latest science and technology news stories
  • These results demonstrate the existence of a class of modifiers of gene expression whose effects are associated with transient changes in DNA methylation of specific loci.
  • The morphological and physiological change of syncytium is considered to be the result of soybean gene expression induced by SCN directly.
  • Similar effects on limb outgrowth and Hoxd gene expression were observed in forelimb cultures.
  • The definition of epigenetics is somewhat variable, with some scientists limiting the term to refer to specific molecular mechanisms that alter gene expression.
  • An emerging issue in evolutionary genetics is whether it is possible to use gene expression profiling to identify genes that are associated with divergence between species and whether these genes have undergone positive selection.
  • From studies on living organisms it is impossible to learn details of the molecular events in IL-6 induced gene expression.
  • There is indeed direct evidence that mechanical stress can generate intracellular signals that regulate gene expression.
  • In us mammals, the way this asymmetry in gene expression seems to hinge on the way cilia rotate to set up a net leftward flow of extraembryonic fluids. The Panda's Thumb: Development Archives
  • Gene expression profiles offer unprecedented insight into the diverse alterations that occur in cryptorchidism. Urology Division Research
  • It is interesting to note in this regard that previous studies have shown that the heat shock family is induced and is important in stress such as hypoxia but these studies had not appreciated the differences between IH and CH and their gene expression underpinnings or the specificity of tissue importance for the survival of the whole organism PLoS ONE Alerts: New Articles
  • Development of the tetracycline ( Tet ) - inducible gene expression system allows genes to be living organism.
  • The developmental stage determines the distribution and duration of gene expression after early intra-amniotic gene transfer using lentiviral vectors. Fetal Gene Therapy Publications and Information
  • Objective To explore the correlation between chromosome fragile site in peripheral blood lymphocytes and proto-oncogene expression rate in patients with hepatocellular carcinoma.
  • However, it remains unclear what factors determine the rate of evolution of gene expression.
  • We propose that in Raji cells the accumulation of a repressor is prevented, thus allowing gene expression.
  • With the development of molecular biology and genetic engineering, intron is found to be especially important in gene expression regulation.
  • It can regulate specific gene expression, cellular secretion and membrane permeability.
  • A single injection of piggyBac transposons could achieve long-term inducible gene expression in the livers of mice in vivo, confirming our multiple-transposon strategy used in cultured cells. Naturejobs - All Jobs
  • For each signature, we calculated the gene expression centroid of the two groups of breast tumors (as determined in the original publications), and then correlated each centroid with cell line expression of the respective signature genes. PLoS ONE Alerts: New Articles
  • It is well established that adaptive responses, such as increased alcohol dehydrogenase gene expression and fermentative metabolism, are initiated under conditions of hypoxia, as well as anoxia.
  • The strategy of these authors entailed the introduction of a polycistronic vector encoding the genes c-Myc, Klf4, and SV40LT and selection of stable episomes that provided persistent gene expression to achieve reprogramming followed by the identification of vector-free subclones after several passages in the absence of selection. BioMed Central - Latest articles
  • KSC have become ideal research target cells in gene transfer, since abnormal epidermal gene expression can be regulated through stem cell gene transfer.
  • 2006 Jan 25;: 1-12, MT, Wagner, K, Delaney, DP, and Kolon, TF Gene expression alterations in cryptorchid males using spermatozoal microarray analysis .. Publications of the Urology Division
  • Important mechanisms for epigenetic alteration of gene expression include DNA methylation and histone acetylation.
  • Complex interactions of receptor and partner Smad with inhibitory Smad, coactivators or repressors, and regulatory proteins ultimately determine the wide range of activation or inhibition of TGF—dependent gene expression.
  • The mechanisms of how mindfulness alters brain and body physiology is under investigation by labs around the world, but preliminary findings demonstrate changes in brain function and structure, immune cytokines, stress hormones and gene expression patterns, to name a few. Susan Smalley, Ph.D.: Mind Body Medicine: Can What You Think and Feel Affect Your Physical Health?
  • They can also be molecular (when, for example, a compound that mimics a hormone alters gene expression) or social.
  • The term epigenetics refers to changes in phenotype or gene expression caused by chemical changes to the DNA, rather than changes in the DNA sequence itself. ScreenTalk
  • With respect to gene expression, transcriptomes from different plants or organs at different physiological states can now be monitored and compared.
  • The coding region is interrupted by several synthetic introns to improve gene expression.
  • The definition of epigenetics is somewhat variable, with some scientists limiting the term to refer to specific molecular mechanisms that alter gene expression.
  • All of the interacting proteins and protein enzymes involved in allosteric regulation are controlled by gene expression.
  • Gasperini S, Marchi M, Calzetti F, Laudanna C, Vicentini L, et al. (1999) Gene expression and production of the monokine induced by IFN-gamma (MIG), PLoS ONE Alerts: New Articles
  • In the eukaryotic genome, SP1 binding sites are well-known enhancer elements in genes with ubiquitous, yet inducible gene expression.
  • Model output is represented by solid lines, gene expression data by dashed lines.
  • Although control of gene expression at the transcriptional level is a key regulatory mechanism controlling carotenogenesis in chromoplasts, it is not the only one.
  • There is a report of some recent genetic research at Gene Expression which seems to me to be overinterpreted.
  • Research trauma state of mononuclear cell gene expression: a serious trauma often leads to fatal sepsis and toxic shock.
  • Statistical analysis of differential gene expression was performed using the limma and lumi R/Bioconductor packages. PLoS ONE Alerts: New Articles

Report a problem

Please indicate a type of error

Additional information (optional):