How To Use Folate In A Sentence
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Folic acid (also known as folate) is a B vitamin that is important for the healthy development of the neural tubes, which eventually become a baby's brain and spinal cord.
Can folic acid reduce the risk of heart defects, too?
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Mushrooms also contain B-complex vitamins, such as riboflavin, niacin, folate and pantothenic acid, not easily found in produce.
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Spinach Spinach is loaded with iron and folate, a B vitamin considered so important that it is now routinely added to flour.
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Folic acid: Also called folate, folacin, or vitamin B9, folic acid is a B vitamin involved in producing thymidine for DNA replication.
You Staying Young
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Mushrooms also contain B-complex vitamins, such as riboflavin, niacin, folate and pantothenic acid, not easily found in produce.
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A woman who gets adequate amounts of the B vitamin folate is much less likely to have a baby with a birth defect affecting the spinal cord.
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Folic acid: Also called folate, folacin, or vitamin B9, folic acid is a B vitamin involved in producing thymidine for DNA replication.
You Staying Young
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Nutritionally, there are many benefits but most interesting is that fact that chickpeas are high in folate, which is a B vitamin necessary for creating serotonin which makes us happy and assists in liver regeneration, amongst other things, and in this respect amongst other properties, chickpeas are also similar to spinach - no wonder I feel so good after eating both!
Archive 2008-02-01
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Folic acid also known as folate is a B vitamin that is important for the healthy development of the neural tubes, which eventually become a baby's brain and spinal cord.
Can folic acid reduce the risk of heart defects, too?
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Inside our bodies, the B vitamins folate and choline work in a delicate balance.
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Several congenital abnormalities are rendered less likely by an adequate folate intake.
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Plasma concentration of homocysteine is a good biomarker for folate deficiency.
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A cup of spinach is an excellent source of folate, which may help reduce your risk of heart attack.
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One cup of blackberries or boysenberries contains just 75 calories but about one-third of the RDA for vitamin C, some folate and iron, and more than 7 grams of fiber.
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Experimental studies have confirmed that folates are highly convulsant if the blood-brain barrier is circumvented.
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Folate that’s produced synthetically is called folic acid.
Pregnancy, Childbirth, and the Newborn
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One cup of groats has 6 grams of fiber and is also rich in copper, niacin, folate, iron, magnesium, manganese, phosphorus and zinc.
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There are also studies on the combination of the short half-life antifolates, chloroproguanil and dapsone, and on pyronaridine, a Chinese synthetic compound.
Chapter 2
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But all beans, including cream-colored navy beans and garbanzo beans, contain iron, folate, zinc, and a bit of calcium.
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Randomized trials of high dose folate supplementation were performed in individuals with a history of precancerous polyps of the colon.
Folic Acid Supplementation - Too Much of a Good Thing?
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If it says "folic acid" then find another vitamin that has the words "L 5 methyl-tetrahydrofolate" or "5 formyl tetrahydrofolate" on the label.
Mark Hyman, MD: Nutrition Tips: Folic Acid: Killer or Cure-All?
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Folate (also referred to as folic acid), 800 mcg with at least 400 mcg coming from the active form or 5-MTHF (or L-methylfolate)
The UltraMind Solution
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Of these 42 patients, 38 had elevated serum folate, a sensitive marker of SIBO.
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Folate is a generic term used for a family of related compounds that exhibit similar vitamin activity within the body.
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In any case, what he found was that treating two different leukemia and lymphoma cell lines with ascorbate at those concentrations before treating them with chemotherapeutic agents, including mechanistically dissimilar agents such as doxorubicin, which intercalates with DNA and causes DNA breaks; methotrexate, which inhibits folate metabolism; cisplatin, which crosslinks DNA; vincristine, which interferes with microtubule function; and imatinib mesylate (better known by its trade name of Gleevec), a selective inhibitor of the activity of a protein called bcr-abl, which is the oncogene that plays a central role in the development of chronic myelogenous leukemia (CML).
Adrian Monck
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Most nicotinic acid and half the folate in foods are not absorbable.
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On the other hand, mercury, arachidonic acid (an inflammatory omega-6 fat from dietary sources like meat and dairy), cortisol (the stress hormone), and homocysteine (because of a lack of folate, B6, or B12) all overexcite the NMDA receptor, leading to cell death.
The UltraMind Solution
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Many breads and baked products are also fortified with folate.
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Oranges are rich in folate, which reduces levels of homocysteine, a body chemical which is associated with heart disease.
The Sun
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Certain medicines, such as some antiepileptic drugs and the antibiotic drug trimethoprim, can interfere with folate levels.
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Folate is found in dark green leafy vegetables, beans and legumes and citrus fruits.
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Vitamins B6, B12, and folate also called folic acid have a strongly positive influence on methylation, which can suppress the production of cortisol.8 Methylation also reduces the harmful amino acid homocysteine.9 Vitamin B6 also aids in the production of both GABA and serotonin, the two brain chemicals most likely to calm the fires of anxiety.10
The Chemistry of Calm
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Whole grains are also important sources of vitamins and minerals, such as thiamin, riboflavin, niacin, folate, selenium, zinc and iron.
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That made us think about pre-natal folate levels, and whether not having enough folate in early gestation could increase your risk not only of neural tube defects but of schizophrenia also.
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Folate molecules on the nanoparticle bind to receptors on tumor cell membranes and the cell immediately internalizes it, because it thinks it's getting the vitamin it needs.
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Even better, chow down on good sources of folate: spinach, romaine lettuce, broccoli, orange juice and green peas.
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Romaine Lettuce: This salad green is packed with folate, vitamin C, and betacarotene.
Dr. Patricia Fitzgerald: Obama Garden Watch: 10 Vegetables Worth A Fist Bump
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Nilsson et al found increased plasma homocysteine along with decreased serum folate, B12, and creatinine levels in 69 percent of demented and non-demented psychogeriatric patients.
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The good news is that you can take the nature-made form of this nutrient -- called methyl folate (and there are a few forms of that too).
Mark Hyman, MD: Nutrition Tips: Folic Acid: Killer or Cure-All?
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Plasma folate levels were measured by radioimmunoassay for the quantitative determination of vitamin B 12 and folate in serum.
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Folate helps break down homocysteine, which can lead to brain atrophy in high levels.
Times, Sunday Times
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Published data from children and pregnant women in Blantyre over the study period show that "quintuple" mutant parasites with two mutations in the dihydropteroate synthase (dhps) gene and three dihydrofolate reductase (dhfr) mutations were highly prevalent in Blantyre over the study period
PLoS ONE Alerts: New Articles
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Bottiglieri T. "Folate, vitamin B12 and neuropsychiatric disorders.
Hyla Cass, M.D.: Is Your Medication Robbing You of Nutrients Part 2: Getting Specific
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The body more readily absorbs folic acid from vitamin supplements and fortified foods than folate from food.
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He and his group have found that folate deficiency breaks chromosomes due to massive incorporation of uracil into human DNA.
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Objective: To study folate - conjugated albumin nanoparticles targeting ... to tumor cells via folate receptor - mediated endocytosis.
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General Apraxin approached every day nearer the town, and laid the unrounding country defolate, fo that it could no longer afford any fubfiftance to the befieged.
Memoirs and Travels of Mauritius Augustus Count de Benyowsky: Consisting of ...
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Folic acid, also known as folate, isn't a medicine.
The Sun
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George had another gene called MTHFR (viii) that made him require very high doses of folate to lower his blood levels of homocysteine, which is a substance very toxic to the brain.
Mark Hyman, MD: 9 Steps to Reverse Dementia and Memory Loss As You Age
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Salad leaves are rich in a range of nutrients including fibre, folate and so-called carotenoids such as alphacarotene, lutein and zeaxanthin.
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We now have an overwhelming consensus amongst well-designed, large, epidemiologic studies suggesting this inverse relationship between folate intake and the risk of developing colon-rectal cancer.
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Meat is also a decent source of nutrients such as vitamin A, vitamin B12, folate, selenium and zinc.
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Several congenital abnormalities are rendered less likely by an adequate folate intake.
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This synergistic activity may be explained by sulfadoxine inhibition of dhps despite the double mutations in the dhps genes, which would interact with pyrimethamine acting to block the remaining folate despite dhfr mutations in the low p-aminobenzoic acid and low folic acid medium mixed with blood.
Reality 1, Behe 0 - The Panda's Thumb
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The absence of a low folate value should not deter the physician from obtaining a duodenal biopsy specimen.
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You need to eat plenty of leafy greens, beans, fruit, and whole grains to get adequate levels of vitamins B6 and B12, betaine and folate (all in the right nature made forms).
Mark Hyman, MD: Nutrition Tips: Folic Acid: Killer or Cure-All?
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Salad leaves are rich in a range of nutrients including fibre, folate and so-called carotenoids such as alphacarotene, lutein and zeaxanthin.
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Most nicotinic acid and half the folate in foods are not absorbable.
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The anticonvulsant drugs phenytoin and valproic acid appear to interfere with folate absorption.
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Whole grains are also important sources of vitamins and minerals, such as thiamin, riboflavin, niacin, folate, selenium, zinc and iron.
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This trial was the first to report a survival advantage from chemotherapy in malignant pleural mesothelioma showing a statistically significant improvement in median survival from 10 months in the patients treated with cisplatin alone to 13.3 months in the combination pemetrexed group in patients who received supplementation with folate and vitamin B12.
Balkinization
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Could similar phenomena occur at other enzymes, particularly allosteric enzymes where structurally similar dihydrofolate plays a regulatory role?
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Natural folates can be found in dark green leafy vegetables (such as spinach, kale, mustard greens, radicchio and Swiss chard), oranges, lentils, asparagus and garbanzo beans.
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Whole grains - These grains, such as pearled barley and oatmeal, are loaded with fiber, potassium, magnesium, chromium, omega-3 fatty acids and folate.
Marketwire - Breaking News Releases
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The 2 studies reported that individuals carrying the MTHFR 677TT variant genotype, which is associated with decreased enzyme activity, lower plasma folate levels, and elevated plasma homocysteine levels, had a statistically significant approximately 2- to 5-fold higher risk of pancreatic cancer compared with individuals with the 677CC genotype.
Meat diet reduces risk of pancreatic cancer | The Blog of Michael R. Eades, M.D.
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Enlarged red cells, called megaloblasts, are caused by vitamin B12 deficiency and folate deficiency.
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Folate and vitamin D deficiency may necessitate vitamin supplementations.
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Spinach: Good source of betacarotene, magnesium, and folate.
Dr. Patricia Fitzgerald: Obama Garden Watch: 10 Vegetables Worth A Fist Bump
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Parsnips -- High in folate and vitamin C. Parsnip soups and mash are fantabulous!
Carolyn Scott: Why Fall Fruits & Veggies Are So Dang Good for You
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This risk only appeared in women who did not eat enough folate or folic acid.
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This is due to the role folate plays in methyl donation in the body.
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A diet rich in citrus fruits offers protection against cardiovascular disease due to compounds like folate, which is necessary for lowering levels of the cardiovascular risk factorhaemocysteine; potassium, which helps lower blood pressure, protecting against stroke and cardiac arrhythmias; and Vitamin C, carotenoids and flavonoids found in citrus fruits, all of which have been identified as having protective cardiovascular effects.
Archive 2008-03-01
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Leafy greens, beans, and orange juice are good sources of folate.
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Other nutrients that are needed to make red blood cells include iron and folate (folic acid).
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Antifolates had never been tried in this disease, but if the drugs could stop aggressive leukemias from growing—even if temporarily—might they not at least partially relieve the eruptions of choriocarcinoma?
The Emperor of All Maladies
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Folic acid, also known generically as folate or folacin, is a member of the B-complex family of vitamins, and works in concert with vitamin B 12.
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Conclusion: Maternal folate deficiency can change the ultrastructure of fetal rat lobus frontalis. It may lead to abnormality of neuronal function and disturb fetal brain development.
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High mean corpuscular volume, which is often a sign of either vitamin B12 or folate deficiency, has been found to be predictive for a risk of colorectal polyps in men.
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Such restrictions in the conformational freedom imposed by denaturants have been suggested through analyses of x-ray B-factors for lysozyme, ribonuclease A, and dihydrofolate reductase.
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Methotrexate is an antimetabolite and antifolate drug used in treatment of cancer and autoimmune diseases.
PLoS ONE Alerts: New Articles
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Other vitamins that are needed to manufacture red blood cells include folate (folic acid) and vitamin B12.
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Minor toxic effects, such as stomatitis, malaise, nausea, diarrhea, headaches and mild alopecia, are common but respond to folate supplementation.
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To top it off, sunlight also destroys your reserves of folic acid, also known as folate or vitamin B9.
You Staying Young
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Multivitamins, folate, and green vegetables protect against gene promoter methylation in the aerodigestive tract of smokers.
Dr. Richard Palmquist: Green Veterinary Medicine: Veggies for Pets
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This wheat has higher levels of folate, betaine, calcium, lutein, Onega-3 fatty acids, fiber, selenium and vitamin B-6 than annual whole wheat.
Julie Brothers: Farm To Fork Across America: In The Body Of Bread
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We need folate, or folic acid, for healthy nerves.
The Sun
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Do not folate the long term intravenous cipro in less amounts, or induce it for immediately than recommended by your doctor.
Wii-volution
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Erythrocyte folate results were corrected for the subjects' hematocrits and serum folate concentrations.
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Methotrexate Toxicity - antimetabolite/antifolate for cancer/autoimmune disease
FinanzNachrichten.de: Aktuelle Empfehlungen
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Folate deficiency appears to facilitate genetic modification at a fragile chromosomal site.
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Whole grains are also important sources of vitamins and minerals, such as thiamin, riboflavin, niacin, folate, selenium, zinc and iron.
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The highest incidence of folate deficiency as measured by serum and red cell folate concentrations is in elderly populations, especially psychogeriatric patients.
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Dried beans and legumes, oranges and orange juice, peanuts and leafy green vegetables all contain folate.
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Objective To examine the methylenetetrahydrofolate reductase ( MTHFR ) gene polymorphism in women with recurrent pregnancy loss ( RPL ).
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Vitamins C, B, folate, pantothenic acid and biotin are easily passed by the body and so need to be included in the daily diet.
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Methionine synthase inhibition causes folate trapping and a reduction in the amount of folate available for thymidine synthesis as described above.
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The active transport mechanism for methylfolate across the blood-brain barrier strictly limits the entry of the vitamin, perhaps for reasons concerned with the excitatory properties of folic acid.
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Epidemiological data from the US and Canada show a blip up in colon cancer cases after the introduction of folate-fortified foods (mostly breads) in these countries, further supporting the idea that high dose folate supplementation may not be such a good idea.
Folic Acid Supplementation - Too Much of a Good Thing?
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This was the reason that food was fortified with the synthetic form of folate called folic acid, which as it turns out is biochemically quite different in its effects.
Mark Hyman, MD: Nutrition Tips: Folic Acid: Killer or Cure-All?
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Good sources of folate include oranges, green leafy vegetables, asparagus and cantaloupe melon.
