How To Use Fibroblast In A Sentence
-
Jr The effect of flavonoids on beta-hexosaminidase transport and endocytosis has been studied in cultured human skin fibroblasts.
Wil's Ebay E-Store
-
Its primary function is at sites of inflammation, where it is produced in macrophages, fibroblasts, and synovial cells.
-
A similar trend was observed for succinate, and for malate plus glutamate oxidation, by digitonin-permeabilized fibroblasts (not shown).
-
There was an organized thrombus in multiple sections of the superior sagittal sinus, with the thrombus showing an ingrowth of fibroblasts.
-
Viral antigen extended, in a time-dependent fashion, from nasal epithelium into the subjacent lamina propria and along olfactory nerves in cells interpreted to be perineural fibroblasts.
-
Avian encephalomyelitis virus ( AEV ) was blindly passaged in chicken embryo fibroblast ( CEF ) cell for six generations.
-
Lorenz HP, Longaker MT, Whitby DJ, Harrison MR, Adzick NS: Scarless fetal skin repair is intrinsic to the fetal fibroblast.
CHOP scarless fetal wound healing publications
-
Methods BMGNeo - IFN - a DNA was transferred into NIH 3 T 3 fibroblasts by the liposome method.
-
In rheumatoid arthritis the e. femoral nerve is often damaged a. principal lesion is an area of fibrinoid necrosis surrounded by fibroblasts 20.
Recently Uploaded Slideshows
-
Fibroblasts cells expressing high amounts of NEFH were strongly misshapen, multinucleated, and had many inclusions, typical changes seen in neuropathies
PLoS ONE Alerts: New Articles
-
These peptides also inhibited proliferation, angiogenesis, and ERK activation induced by basic fibroblast growth factor with similar potency and efficacy.
-
The researchers also added connective tissue cells called fibroblasts to the mix as a crucial third ingredient.
-
Treatment with sucralfate did not significantly alter the number of capillaries or myofibroblasts.
-
Interestingly, depending on the gestational age, myofibroblasts can disappear from the wound site, a phenomenon that has been correlated to scarless wound healing.
-
Kreth G, Solovei I, Koehler D, Saracoglu K, et al. (2005) Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes.
PLoS ONE Alerts: New Articles
-
The anormal proliferation of the cardiac fibroblast can facilitate the progress of the remodeling of the cardiac ventricle and accelerate the process of the heart failure.
-
This work led to my appreciation of the role of specific serum factors in the control of cell multiplication and the demonstration that a multiplication-stimulating factor in calf serum for chicken fibroblasts was the same as somatomedin.
Howard M. Temin - Autobiography
-
Current research suggests that, during the final stages of wound healing, myofibroblasts, again, generally identified by [alpha] smooth muscle actin expression, die through apoptosis to leave an acellular scar.
-
We would like to mention that we found a different behavior in fibroblasts on laminin-coated glass coverslips.
-
In this study we report normal UV-upregulation of reporter expression in xeroderma pigmento-sum group E fibroblasts, consistent with normal TCR.
-
Electron microscopy showed a striking increase in collagen with minimal fibroblast proliferation.
-
Fibroblasts infected with retroviral constructs expressing the indicated cDNA (top) were harvested 9 days postinfection, and whole cell extracts assayed by western blot with the indicated antibodies (left).
PLoS ONE Alerts: New Articles
-
Collagen is synthesized by fibroblasts, the living cells present in all connective tissue, so named because they generate fibres - of collagen.
-
Regulation of interleukin-1beta-induced chemokine production and matrix metalloproteinase 2 activation by epigallocatechin-3-gallate in rheumatoid arthritis synovial fibroblasts.
The Autoimmune Epidemic
-
The Boer goat ear skin fibroblast nucleo-transferred embryos and bovine-goat(Boer) interspecies clone embryos have been evaluated by studying the ultrastructure of Boer goat embryos in vivo.
-
Guizhou isolate of newcastle disease virus could grow on chicken embryo fibroblast and resulted in cytopathogenic effect.
-
The adventitia is rich in collagen bundles, and contains some cells that may be fibroblasts or macrophages.
-
ObjectiveTo study the role of mitomycin C(MMC) and hyaluronic acid (HA) on the proliferations of normal and photorefractive keratectomy(PRK) rabbit corneal fibroblasts.
-
In 2000, the organism was cultured in human fibroblast cell line by centrifugation shell vial technique.
-
In adults, fibroblasts in connective tissue rarely undergo division.
-
Electron microscopy showed a striking increase in collagen with minimal fibroblast proliferation.
-
A dense band of fibroblasts, collagen fibers, proteoglycans, and occasional mast cells encase the granuloma.
-
Tumors are a complex mix of neoplastic cancer cells and normal cells - inflammatory and immune cells, endothelial cells, fibroblasts, pericytes, and others, collectively known as stromal cells.
Undefined
-
This molecule is the most potent chemotactic agent for monocytes, lymphocytes, neutrophils, and fibroblasts and has a significant stimulant effect on the formation of granulation tissue.
-
Whole lysates of mouse organs (brain, liver, kidney, spleen, heart, and lungs), embryonic day 12 embryos, and cultured fibroblasts, clarified by high-speed centrifugation, were preabsorbed on the column with coupled preimmune serum.
PLoS Biology: New Articles
-
The fibroblasts were used between culture passages 3 and 6.
-
Fibroblast-like cells migrate into the empty segments of the developing blastema to establish cell lines that later become myoblasts.
-
The vaccine virus was also grown in guinea pig fibroblast cells.
Varicella (Chickenpox) Vaccine
-
Very little effect was observed in either the distribution or the total beta-hexosaminidase activity in normal fibroblast cultures.
Wil's Ebay E-Store
-
Inflammatory myofibroblastic tumor, also referred to as inflammatory fibrosarcoma, is a rare tumor composed of myofibroblastic spindle cells of uncertain etiology and disputed nosology.
-
The tumor shows diffuse growth of plump fibroblasts in a cartilaginous stroma with calcification.
-
The models explain the trigonal pyramidal shape of fibroblast growth factor and provide a basis for interpretation of protein crystal structures.
-
NgHexA was more efficiently taken up than the wild-type HexA and delivered to lysosomes, where it degraded accumulated substrates including GM2 ganglioside (GM2) when administered to cultured fibroblasts derived from a Sandhoff disease (SD) patient.
Naturejobs - All Jobs
-
We found no regulation in proliferation data from dedifferentiated or embryonic cells, and we observed a dual control in proliferation data from normal mouse bone marrow cells, and from normal human fibroblasts (however, the latter was a short series).
PLoS ONE Alerts: New Articles
-
The horse dermal fibroblast (NBL-6) cells presented in the digital image above were resident in an adherent culture stained for F-actin with Alexa Fluor 488 conjugated to phalloidin (green fluorescence), and for DNA with the bis-benzimidazole dye Hoechst 33258
Undefined
-
The persistence of the myofibroblastic phenotype in the areas of active fibrosis is a characteristic finding in fibrotic lung disease.
-
Once grown to confluency, the cells were passaged twice in the ratio of 1: 6 to obtain pure fibroblast cultures.
-
FGFRL1, the gene for the fifth member of the fibroblast growth factor receptor (FGFR) family, is found in all vertebrates from fish to man and in the cephalochordate amphioxus.
BioMed Central - Latest articles
-
Once the fibroblast is fully mature, displayed by being completely surrounded by the matrix, it is called a fibrocyte.
CreationWiki - Recent changes [en]
-
Fig. 1B) and of adventitial fibroblasts (data not shown).
PLoS ONE Alerts: New Articles
-
Both have been shown to inhibit DNA synthesis and arrest fibroblast growth without apoptosis and thus preserve the cytoarchitecture.
-
The fibroblast line grows adherently to glass and plastic in culture and is generally utilized as a transfection host for virus genomes and recombinant plasmids.
Undefined
-
Platelet-derived growth factor is a major polypeptide growth factor found in human serum, platelets and fibroblasts and is a potent mitogen for cells of mesenchymal origin.
-
Typical plaques showed proliferation of myofibroblastic cells with myxoid stroma.
-
Phagocytosis of the RTHDF fibroblasts was studied using carboxylate-modified polystyrene fluorescent latex beads with a diameter of 1.0 µm (Sigma-Aldrich) as described by Ganassin et al. [63].
PLoS ONE Alerts: New Articles
-
Moreover, BALF from allergen-stimulated airways was mitogenic for airway fibroblasts.
-
Conclusion Trabeculectomy with applying suramin may enhance the success rates of surgery by suppressing the fibroblasts and synthesis of newly formed collagen fibers, and by inhibiting scar formation.
-
Fibroblasts are found in connective tissue, which includes cartilage and the cellular matrix known as stroma that provides support to body structures, such as organs, glands and also tumors.
PhysOrg.com - latest science and technology news stories
-
The derm is is composed of fibroblasts, collagen, matrix proteins, and elastic fibers.
-
This application of topical nitric oxide may stimulate wound fibroblasts to increase collagen synthesis and remodeling.
-
Objective To observe the differences of colony forming unit-fibroblastic(CFU-F) numbers in bone marrow aspirated in various ways from New Zealand white rabbits.
-
The middle layer, or dermis, contains connective tissue, small blood vessels, sweat and oil glands, nerves, and cells that produce collagen, called fibroblasts.
-
This fact appears in the literature as the discrepancy between sensitivity curves measured with a monochromatic source and with polychromatic radiation observed in normal human skin fibroblasts.
-
Taxifolin and hesperitin inhibited receptor-mediated endocytosis of beta-hexosaminidase by fibroblasts up to 50% of control uptake.
Wil's Ebay E-Store
-
The phenotype of cancer invasion depends on composition and density of the ECM, and can vary from amoeboid blebbing, mesenchymal fibroblast-like motility and multicellular streaming or chain migration
PLoS ONE Alerts: New Articles
-
The two studies showing that kinetin affects cell differentiation in keratinocytes and fibroblasts were done in vitro.
Simple Skin Beauty
-
In our studies, fibroblast contractile machinery was observed to function entirely within pseudopods, while GFP-alpha-actinin concentrated in pseudopod tips and cortex.
-
Regulation of interleukin-1beta-induced chemokine production and matrix metalloproteinase 2 activation by epigallocatechin-3-gallate in rheumatoid arthritis synovial fibroblasts.
The Autoimmune Epidemic
-
A similar sheet of human fibroblasts was wrapped around the media to provide the adventitia.
-
Fibroblasts grow into the exudate from both the visceral and parietal pleural surface to produce an inelastic membrane called the pleural peel.
-
This phenotypic conversion is specific to cancer cells and does not occur in co-cultures of GFP labeled fibroblasts with myogenic C2C12 cells.
PLoS ONE Alerts: New Articles
-
Unlike a moving fibroblast, however, the extending axon also grows in size, with an accompanying increase in the total surface area of the neuron's plasma membrane.
-
Their excentrically located, usually kidney-shaped nucleus, which is always darker than in the fibroblasts, is a secure criterion for their identification.
-
Certain cells, such as fibroblasts - cells responsible for producing extracellular matrix in wound healing and tissue remodelling - will migrate along the tracks.
-
Widely distributed in the embryo as a loose connective tissue, mucoid tissue is composed of large stellate fibroblasts in an abundant intercellular substance, which is homogeneous and soft.
-
Lin RY, Sullivan KM, Argenta PA, Lorenz HP, Adzick NS: Scarless human fetal skin repair is intrinsic to the fetal fibroblast and occurs in the absence of an inflammatory response: In situ hybridization and immunohistochemical studies.
CHOP scarless fetal wound healing publications
-
The anormal proliferation of the cardiac fibroblast can facilitate the progress of the remodeling of the cardiac ventricle and accelerate the process of the heart failure.
-
Attracted by cytokines and growth factors, fibroblasts migrate into wound sites within several days of injury.
-
In this study, we demonstrated by parabiosis that type I alveolar epithelial cells and lung fibroblasts as well as interstitial monocytes/macrophages could be derived from circulating slem/progenitor cells.
-
In the Journal of Clinical Investigation published online November 16, they demonstrate the critical role for fibroblast activation protein (FAP), expressed by one type of these so-called "stromal" cells, in promoting tumor growth in mice.
Undefined
-
It has been shown that conditioned media from fibroblasts from patients with idiopathic pulmonary fibrosis stimulates angiogenesis.
-
To include a test system avoiding this general problem, primary human embryonic fibroblasts were added to the study.
-
MRC-5 cells, which grow adherently in culture and exhibit fibroblast morphology, may double in population size 42 to 46 times before the onset of senescence.
Undefined
-
These embryonal carcinoma (EC) cells could be grown on feeder layers of irradiated fibroblasts.
The 2007 Nobel Prize in Physiology or Medicine - Advanced Information
-
Baf, Bafilomycin A1; BH, Bcl-2 homology; CHX, cycholoheximide; GFP-74Q, GFP-tagged exon 1 mutant htt fragment; htt, huntingtin; MEFs, mouse embryonic fibroblasts; 3MA, 3-methyl adenine; PE, phosphatidylethanolamine; STS, staurosporin; TNF -
Naturejobs - All Jobs
-
VEGF was mainly secreted by hepatocytes, and was also positively expressed in liver sinusoid endothelial cells, fat-storing cells, myofibroblast and monomorphic nucleus cells.
-
Sugawara S, Tada H, Takada H, Shimauchi H, et al. (2000) Cleavage of CD14 on human gingival fibroblasts cocultured with activated neutrophils is mediated by human leukocyte elastase resulting in down-regulation of lipopolysaccharide-induced IL-8 production.
PLoS ONE Alerts: New Articles
-
Fibroblasts stably infected with a retroviral construct expressing hemagglutinin (HA) - tagged MEOX2 were harvested 15 days postinfection and subjected to chromatin immunoprecipitation with HA, PolII, or preimmune IgG antibodies.
PLoS ONE Alerts: New Articles
-
For example, bronchial epithelial cells exposed to a compressive stress in vitro elicit a profibrotic response in unstressed fibroblasts.
-
Mikos AG (2001) Integrin alpha (v) beta (3) is involved in stimulated migration of vascular adventitial fibroblasts by basic fibroblast growth factor but not platelet-derived growth factor.
PLoS ONE Alerts: New Articles
-
Widely distributed in the embryo as a loose connective tissue, mucoid tissue is composed of large stellate fibroblasts in an abundant intercellular substance, which is homogeneous and soft.
-
The possible role of fibroblast growth factors in organization of the limb blastema is explored and the similarities between vertebrate and invertebrate control of regeneration are discussed.
-
A human gene can be inserted into fibroblasts using a retroviral vector, and the skin then grafted back to the donor.
-
Objective To establish the technique of Culture of normal human melanocyte , keratinocyte and fibroblast isolated from the same donor.
-
Treatment with sucralfate did not significantly alter the number of capillaries or myofibroblasts.
