How To Use fibrinogen In A Sentence
- Plasminogen binds to both fibrinogen and fibrin, thereby being incorporated into a clot as it is formed.
- One of the key reactions in the mammalian blood coagulation and hemostatic process is the cleavage of the zymogen prothrombin to thrombin which in turn activates fibrinogen to fibrin, eventually resulting in clot formation.
- Inherited dysfibrinogenemia is caused by mutations in the coding region of the fibrinogen A, B, or gamma gene.
- Fibrinogen is modified by thrombin to produce fibrin monomers that are the primary constituent of the fibrin clot.
- Monitoring these tests along with fibrinogen and platelet counts provides important information for the early detection of hemostatic activation and for monitoring the severity of the condition.
- The Amphioxus has no gene for fibrinogen, the final step in the modern clotting cascade, yet it still clots its haemolymph. The Panda's Thumb: Ian Musgrave Archives
- In the assay, the addition of thrombin to citrated plasma causes the conversion of fibrinogen to fibrin, yielding a stops bleeding much quicker.
- This leads to extravasation of fibrinogen and other plasma proteins, activation of the clotting system, and deposition of a fibrin gel in the extravascular space.
- Currently, cryoprecipitate is the only source of concentrated fibrinogen available.
- Thrombin forms clots and thrombi by removal of fibrinopeptides A and B from fibrinogen to form fibrin.
