differentiation

[ US /ˌdɪfɝˌɛntʃiˈeɪʃən, dɪfɝˌɛnʃiˈeɪʃən/ ]
[ UK /dˌɪfəɹˌɛnʃɪˈe‍ɪʃən/ ]
NOUN
  1. a discrimination between things as different and distinct on the basis of their characteristics or attributes
    it is necessary to make a distinction between love and infatuation
  2. (biology) the structural adaptation of some body part for a particular function
    cell differentiation in the developing embryo
  3. the mathematical process of obtaining the derivative of a function
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How To Use differentiation In A Sentence

  • The presence of small lymphocytes in serous cavity fluid can pose great difficulty in the differentiation between a low-grade lymphoproliferative disorder and reactive lymphocytosis.
  • Objective To study the effects of retinoic acid on the differentiation of human rhabdomyosarcoma cells and on the expression of myogenic regulatory factor (MRF).
  • These authors, by using differential and density-gradient centrifugation techniques, achieved the differentiation of the microbody fraction from lysosomes, microsomes, and mitochondria.
  • Myostatin is a member of the transforming growth factor-beta (TGF-β) superfamily of growth and differentiation factors and is a primary regulator of muscle growth both pre - and postnatally, primarily via inhibition of myoblast proliferation and differentiation PLoS ONE Alerts: New Articles
  • The pragmatic differentiation between classificatory, potential and actual affines is undertaken in accordance with the proscriptive principles described above, and is framed within a consubstantial conception of relatedness.
  • What is the causal relation between the pattern of division and cell differentiation?
  • Objective To assess the effect of repeated gonadotropic stimulations on the developmental potential and growth differentiation factor-9 (GDF-9) expression of mouse oocytes.
  • But at least one religious leader believes the ability to use dedifferentiation to create human stem cells would eliminate the controversy. Cells That Go Back in Time
  • Torque transfer is a function of the internal gearing, which generates frictional resistance to differentiation through the axial and radial thrust forces of the gears in the differential.
  • Histologically, the tumor was composed of two distinct components - an epithelioid component with granular cytoplasm that stained for synaptophysin, melan-A, calretinin, and vimentin compatible with adrenocortical differentiation, and a pleomorphic to spindled component that was positive for desmin and myogenin, compatible with rhabdomyosarcomatous differentiation. BioMed Central - Latest articles
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