How To Use Cytotoxin In A Sentence
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Because bioreductive drugs are activated to form highly effective cytotoxins under hypoxic conditions, they can be used to inactivate hypoxic tumor cells that are refractory to the direct cytotoxicity of hypericin-PDT.
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These results suggest that combining NMDAR antagonist ketamine with an astrocytic inhibitor or cytotoxin, which is suitable for clinical use once synthesized, might be a potential strategy for clinical management of neuropathic pain.
BioMed Central - Latest articles
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The possibility that a cytotoxin may play a role in the pathogenesis of EPEC infection had been suggested.
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The gold standard for the diagnosis of C. difficile-mediated disease is a cytotoxin assay.
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Previous studies have indicated that there is considerable variation in the quantity or activity of vacuolating cytotoxin produced or secreted by H. pylori isolates.
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Nilewski et al. Total synthesis of a chlorosulpholipid cytotoxin associated with seafood poisoning
Undefined
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This endogenous nitric oxide can lead to de-repression of the genes encoding systems that are concerned with the detoxification of nitric oxide and the repair of proteins potentially damaged by the cytotoxin.
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These aberrations can be formed by cytotoxins produced by many viral and some bacterial illnesses.
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Subtilase cytotoxin is produced by certain kinds of E. coli bacteria, causing bloody diarrhea and a potentially fatal disease called haemolytic uraemic syndrome (HUS) in humans.
Health News from Medical News Today
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These anti-cancer drugs are actually cytotoxins, or ' cell-killing drugs ' which do not differentiate between good and bad cells.
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Recently, it has been suggested that nitric oxide produced during an inflammatory response could become an endogenous cytotoxin, with mutagenic and/or carcinogenic properties.
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The fer-de-lance, a pit viper from Central and South America, has in its venom several highly effective cytotoxins - chemicals that target living cells.
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GenSpera's technology platform combines a potent cytotoxin (12ADT) with a pro-drug delivery system that activates the drug only within the tumor.
The Earth Times Online Newspaper
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While remaining innocuous to the normal tissues, the prodrug is converted to the cytotoxin by the enzyme localised at the tumour.
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Tocopherols protect against the side effects of radiotherapy and cytotoxins.
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It is thought that certain strains of H. pylori (especially east-Asian cytotoxin-associated gene [cagA] - positive strains) might carry an increased risk of developing gastric cancer, but currently identified cagA genotypes in the Asia-Pacific are not associated with cancer.
PhysOrg.com - latest science and technology news stories
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It is known that Salmonella and E. coli can produce the potent cytotoxin nitric oxide as a side product of nitrate metabolism.
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If cytotoxins have no ‘accomplice’ in the cell interior, chemotherapy is usually destined to fail - chemoresistance is the result.
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Therefore, the present study is to validate the coadministration effects of a neuronal noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist ketamine and astrocytic cytotoxin L-alpha-aminoadipate (LAA) on spinal nerve ligation (SNL) - induced neuropathic pain.
BioMed Central - Latest articles
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One cell line responded to genotoxins and the other cell line responded to cytotoxins.
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A study has demonstrated that cytotoxin production was the most common virulence factor compared to adhesive and invasive ability.
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GenSpera's has combined a plant-derived cytotoxin with a delivery system that releases the drug only within the tumor.
San Antonio Business News - Local San Antonio News | The San Antonio Business Journal
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While remaining innocuous to the normal tissues, the prodrug is converted to the cytotoxin by the enzyme localised at the tumour.
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Apoptosis can be induced by immune cells and cytotoxins, and by changes in homeostatic signals.
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H. pylori (especially east-Asian cytotoxin-associated gene [cagA] - positive strains) might carry an increased risk of developing gastric cancer, but currently identified cagA genotypes in the Asia-Pacific are not associated with cancer.
EurekAlert! - Breaking News
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Because bioreductive drugs are activated to form highly effective cytotoxins under hypoxic conditions, they can be used to inactivate hypoxic tumor cells that are refractory to the direct cytotoxicity of hypericin-PDT.