How To Use Chromosomal In A Sentence

Chromosomal abnormalities included gonosomal aberrations in 5 cases.
For example, acesulfame-K induces chromosomal aberrations; sucralose is associated with several effects in animals, is weakly mutagenic, and increases the glycosylated hemoglobin in diabetic patients.
This process is commonly manifested in chromosomal monosomics in which the most common effect is an approximate twofold increase of target gene expression throughout the genome.
It has a wide cell tropism and remains extra-chromosomal, therefore minimising the risk of insertional mutagenesis.
The chromosome 22q11. 2 deletion is a chromosomal difference, one that may or may not "run in the family" (meaning it's hereditary). Velocardiofacial, conotruncal anomaly face and Opitz G/BBB syndromes

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I didn't know how many eggs I'd have left after treatment or if any remaining eggs would be chromosomally viable. Pregnancy After Breast Cancer
Abnormal levels of alpha-fetoprotein in amniotic fluid or maternal blood may indicate an increased risk for a variety of birth defects or chromosomal disorders. Glossary
Thus a gene for chromosomal fratricide will spread as surely as a murderer will inherit the Earth.
So it may be advisable for babies with this type of lymphatic malformation to have chromosomal analysis performed.
Such results can be related to the formation of meiotic trivalent in the hybrids leading to the production of viable aneuploid gametes and post-zygotic elimination of embryos due to chromosomal non disjunction events at meiosis. The Rise of Human Chromosome 2: Beyond the Deme - The Panda's Thumb
Fetal cells contained in the amniotic fluid will be tested for Down syndrome and other chromosomal abnormalities.
Critical to this hypothesis is the identification of insulator or boundary elements that delimit chromosomal domains.
To make a very long story short, it appears that a common human variant of the microcephalin gene originated on a chromosomal region that separated from the human lineage over 1 million years ago, only to come back “introgress” into H. sapiens about 37,000 years ago. The Panda's Thumb: Andrea Bottaro Archives
However, the genetic determinants appear to be chromosomal.
The researchers ran a test commonly used to evaluate children for neurodevelopmental disorders such as autism called a chromosomal microarray. RedOrbit News - Technology
The researchers launched the study to compare the newer screening, called chromosomal microarray analysis (CMA), against the tests that the ABC News: ABCNews
Oocytes and sperm are haploid, with one set of chromosomes, whereas somatic cells are diploid, with two chromosomal sets.
Some chromosomal variation is evident in the New Zealand members of the K. ericoides complex, which helps to support the recognition of additional taxa within this aggregate species.
Biologic theorists believe chromosomal or nervous system disorders are the cause.
Chromosomal sex determination can also be more complex, with multiple X and Y chromosomes, or maternal, as in the carrion fly Chrysomya rufifacies.
Gross chromosomal disturbance would certainly seem likely to cause either cell death or conversion to a cancerous state.
The most direct way to assess chromosomal aneuploidy is to evaluate chromosome numbers in metaphase cells.
Abnormal levels of alpha-fetoprotein in amniotic fluid or maternal blood may indicate an increased risk for a variety of birth defects or chromosomal disorders. Glossary
More generally, there is a need to discriminate between the effects of chromosomal rearrangements and linked genic incompatibilities in both plants and animals.
The risk of bearing a child with certain chromosomal birth defects increases as a woman ages.
The type of chromosomal aberrations detected in the azoospermic and oligozoospermic men are given in Table I.
Analysis of chromosomal karyotype in 637 cases of genetic counseling shows that abnormal rate are more higher in Down′s syndrome, Turner syndrome, primarily or secondary amenorrhea cases.
These tests score either chromosomal structural aberrations at metaphase or micronuclei at interphase.
The handicap is caused by a chromosomal abnormality which basically means that there is an additional chromosome in the cells.
Conventional cytogenetics is a validated technique to study the acquired gross chromosomal aberrations associated with human cancer.
Lack of extrusion of the palindrome may explain why it was not deleted from the chromosomal locus during growth of the recombinants.
The telomeres being studied in Lee's project act as a kind of protective cap for chromosomal ends - much like the plastic aglet at the end of a shoelace, for example - allowing cells to retain their biological information. Newswise: Latest News
The gene content of chromosomal segments conditioning quantitative resistance to multiple pathogens was inspected.
chromosomal defect
Although triploidy and haploidy of chromosomal regions in humans often cause viable or semiviable developmental defects, it is difficult to identify regions of the genome that are haplolethal.
We have been examining the potential use of oligonucleotides to direct nucleotide exchanges in episomal and chromosomal genes.
Moreover, we present data on the variability of the first six equine Y-chromosomal microsatellite markers in the domestic horse and other equine species.
The field of this course mainly studies the chromosomal disorder, single gene disorder, polygenetic disorders, genetic diagnosis and counseling.
allopolyploids are generated by hybridization between two related species. the hybrid is sterile. however, sometimes chromosomal doubling occurs, restoring fertility. if the two parental species are diploid, the resulting allopolyploid is called allotetraploid. Lynn Margulis: "Definitely a Darwinist" - The Panda's Thumb
For example, SINES and LINES can cause insertional mutagenesis, hybrid dysgenesis, chromosomal rearrangements, etc. Junk DNA, Junk Science, and The Onion Test - The Panda's Thumb
Its production - spermatogenesis - involves cell divisions and reorganization of chromosomal material, which generates genetic diversity.
This may be related to the large size of the chromosomal DNA to be deleted, to polymorphism at this locus, or to specific effects of the donor DNA.
No significant increase in cells with chromosomal aberrations, polyploidy or endoreduplication was observed at the concentrations analyzed.
Chromosomal analysis through blood tests is also available in some cases.
But the sub-text in all affirmative action debates is the fallacious belief that blacks selected to benefit from it are hopelessly and helplessly genetically inferior -- that their DNA is chromosomally deficient, if not defective. Irene Monroe: Theory of Blacks' Intellectual Inferiority Rears Ugly Head at Harvard
Objective : to assess the relationship between azoospermia or severe oligozoospermia and Y chromosomal microdeletions.
The man had been studying the videotape of the scan and had concluded it was a severe case of chromosomal non-disjunction. GRACE
The risk of chromosomal abnormalities is very low for my age which is also a relief.
She won the Nobel Prize in 1983 for her discovery of chromosomal instability 50 years ago.
Recall that a twofold increase in secondary mutation frequency in recD was also seen for chromosomal loci.
The rate difference may show a relationship between the development tumor at jaw face and chromosomal anomaly.
Initially I started to work on virus-induced chromosomal modifications and at the same time received relatively solid training in diagnostic bacteriology and virology, both of them at that time in an early stage of development. Harald zur Hausen - Autobiography
When the researchers injected iPS cells derived from a chromosomally normal individual, the resulting tumors spawned elaborate networks of blood vessels to feed themselves. How Down Syndrome Protects Against Cancer | Impact Lab
This conclusion was further supported by the fact that large part of the secretome was found to be coded by a piece of extra-chromosomal DNA called plasmid, which is, simply, the most mobile part of the whole bacterial genome Health News from Medical News Today
As in mammals, both chromosomal constitution and cell interactions are involved in the development of germ-cell sexual phenotype.
This cell line detects a wide variety of mutagenic lesions, including point mutations, deletions and various types of chromosomal aberrations.
The tissue is sent to the laboratory where the fetal villi are dissected from the maternal decidua and either processed directly or cultured for chromosomal, DNA or biochemical analysis.
You don't really believe he has a chromosomal abnormality, do you? AND GOD CREATED THE AU PAIR
As a complementary approach, chromosomal revertant mutants of cdc7 - PD1 were isolated in the hope that mutations that promote septation and counteract the septation defect of cdc7 - PD1 would be identified.
The number of cells with chromosomal aberrations among 100 well-spread metaphases was recorded.
Chorionic villous sampling was also performed to rule out a fetal chromosomal anomaly that occurs in 6 to 8 percent of such cases. Lower Urinary Tract Obstruction (LUTO)
Boys with this chromosomal alteration have a progressive testicular failure with spermatogenic failure and reduced testosterone concentrations in late adolescence and early adulthood. JAMA current issue
Conclusion: Gene have different degree loses in abnormal chromosome karyogram, result in chromosomal gene linkage not equilibrium and and emergence clinical effect.
It was also possible that drugs used to stimulate ovaries could trigger chromosomal abnormalities.
Looking for alternatives Evans discovered that chromosomally normal cell cultures could be established directly from early mouse embryos. The 2007 Nobel Prize in Physiology or Medicine - Press Release
Thus a gene for chromosomal fratricide will spread as surely as a murderer will inherit the Earth.
In fact, we did not find any informative marker in the three chromosomal divisions around the centromere of this chromosome.
Those chromosomal rearrangements that lead to the loss of an essential gene or DNA segment would make the cells inviable.
The centromere is responsible for two key chromosomal functions in mitosis and meiosis.
The human genome project allowed geneticists to develop chromosomal microarray (CMA), also referred to as molecular karyotyping. PhysOrg.com - latest science and technology news stories
This suggests that the insertion could affect either the transcriptional or the transpositional activity of the retrotransposons or the epigenetic state of that chromosomal region.
These effects include the induction of chromosomal aberrations and sister chromatid exchange.
The genetic structure of this species is complex, with several recognized "chromosomal forms" that differ ecologically.
The tissue is sent to the laboratory where the fetal villi are dissected from the maternal decidua and either processed directly or cultured for chromosomal, DNA or biochemical analysis.
Klinefelter syndrome is still the most common chromosomal disease, balanced translocation accounts for largest proportion of autosomal abnormality.
The results are discussed in relation to the chromosomal evolution of the genus.
In chromosomally normal mice, the standard two copies of the Dscr1 gene produce just enough protein to help reign in normal blood-vessel growth, but not enough to stem the angiogenesis overload triggered by a developing tumor. How Down Syndrome Protects Against Cancer | Impact Lab
Chromosomal abnormalities that occur when nonmatching pairs of chromosomes swap genetic information are known as chromosomal translocations. Medlogs - Recent stories
Groups with chromosomal sex determination systems are expected to evince differences among males and females in absolute DNA content.
If you transfer to the uterus embryos that are confirmed to be chromosomally normal and develop well, reaching the blastocyst stage, the chance of producing a child is very high, about 70%. Embryo 'health check' could increase pregnancy rates through IVF treatment
Chromosomal translocations are known to contribute to the development or progression of many types of cancer.
The colicin V is exported by CvaA and CvaB into the cytoplasmic membrane and outer membrane by a host chromosomal gene product TolC PLoS ONE Alerts: New Articles
Conclusion:Maternal serum PAPP-A might be a marker for predicting fetal chromosomal anomaly.
We find that full function of the endogenous rDNA locus depends not merely on the presence of the rDNA cistrons but also on chromosomal context.
Death was the great and old man had warred against it so fiercely and so long that was engraved on the deepest of the chromosomal was the other side of the battle, and the war was called And the universe didn't give a damn about either side. In Alien Hands
Generation of entire chromosomal maps has been a central problem in genetics right from its early years.
Following that nucleation step, silencing spreads along the chromosome, as observed or proposed for related systems and as supported by the fact that Swi6 can oligomerize and cover large chromosomal regions.
Maize hybrids with a type of teosinte from Guatemala, known as Florida teosinte, were partially sterile, exhibited incomplete chromosomal homology, produced some univalents, and had reduced linkage distances.
Furthermore, laboratory studies of the uptake of exogenous chromosomal DNA in bacteria have also demonstrated that recombination can mediate the process of adaptive evolution.
Individuals with developmental delay or mental retardation, birth defects, multisystem medical problems, unusual facial features or failure to thrive are referred for evaluation and diagnosis of a genetic syndrome or a chromosomal abnormality. Evaluation, counseling, follow-up care
Folate deficiency appears to facilitate genetic modification at a fragile chromosomal site.
In collaboration with Dr. Barr, who discovered the gene involved in alveolar rhabdomyosarcoma, Dr. Womer and others have used the chromosomal changes in sarcomas to determine response to treatment. Pediatric cancer research
In these studies, the duplications are produced by transformation of the cloned DNA and its insertion into ectopic chromosomal locations.
Even if there are âintelligenceâ genes, they are not going to travel (chromosomally) with a non-existent race gene, and very very unlikely to travel with a gene like melanin-production (empirical question...although I think this too has been answered with genetic epidemiology studies about interâ and intra-continental variance). The Volokh Conspiracy » 1. Science, Faith, and Not Ruling Out Possibilities
These tests score either chromosomal structural aberrations at metaphase or micronuclei at interphase.
Complete eukaryote chromosomes were investigated for intrachromosomal duplications of constitute a major part of the genome.
The objective of this study was to determine the chromosomal constitution and sperm characteristics among Indian males with severe male factor infertility.
Several chromosomal abnormalities were observed in the tetraploid albino plants.
Although this assay is very sensitive for detecting chromosomal loss, it is unable to detect non-disjunction and chromosome gain.
I started to work eagerly on the induction of specific chromosomal aberrations in adenovirus type 12-infected human cells, simultaneously studying a DNA-replication disturbance of individual chromosomes in human lymphoblastoid and lymphoma cell lines, and, to please my mentor, I demonstrated electron microscopically the presence of EBV particles directly in individual serologically antigen-positive Burkitt's lymphoma cells. Harald zur Hausen - Autobiography
The blood test could identify certain chromosomal changes that guide physicians to prescribe certain anticancer drugs.
Dr. Verlinsky helped pioneer in the U.S. a prenatal diagnosis technique known as chorionic villus sampling, which screens fetuses for genetic and chromosomal disorders at 10 weeks, at least six weeks earlier than the test known as amniocentesis. Chicagotribune.com -
The chromosomal complement of each cell is divided into the autosomes and the sex chromosomes.
A rise in intracellular calcium at the onset of anaphase could regulate the polar ejection force by shutting down the centriolar turbines, but defective regulation could result in an excessive force that contributes to the chromosomal instability characteristic of most cancer cells. Revisiting Rivista - The Panda's Thumb
Here we present evidence that the chromosomal hypermutation is promoted by recombination.
However, if the obstruction is related to underlying chromosomal or genetic conditions, the risk of recurrence equals the risk of recurrence of the underlying condition. Lower Urinary Tract Obstruction (LUTO)
In our experiments, we used three strains carrying chromosomal duplications with known endpoints.
Amniocentesis is performed for viral cultures, chromosomal analysis and alpha-fetoprotein levels. Hydrocephalus
Prior to this report, chromosomal rearrangements accounted for all erythroblast transformation-specific gene fusions associated with prostate cancer. MedPageToday.com - medical news plus CME for physicians
The complete absence of untransformed animals in these transformed lines suggested that these stable lines were homozygous for a chromosomal insertion of the transforming plasmid.
Creationists sometimes try to argue that what we consider straightforward, well-demonstrated cytological and genetic events don't and can't occur: that you can't get chromosome rearrangements, or that variations in chromosome number and organization are obstacles to evolution, making discussions of synteny, or the rearrangement of chromosomal material in evolution, an impossibility. Life will find a way - The Panda's Thumb
The chromosomal location, patterns of genomic dispersion, and copy numbers of its tandemly arranged units varied between the species.
Cells containing any of these types of chromosomal alterations were considered aberrant cells.
For this humanized yeast screen, an S. cerevisiae strain was created harboring a deletion of the chromosomal yeast HSF locus (yhsfΔ) and which expresses a wild-type episomal copy of yeast HSF from the galactose-inducible, glucose-repressible PLoS Biology: New Articles
The rate difference may show a relationship between the development tumor at jaw face and chromosomal anomaly.
The chromosome 22q11. 2 deletion is a chromosomal difference, which may or may not run in the family. Deletion of a small piece on the long arm of chromosome 22
In karyotyping, forms of which have been around since the 1960s, geneticists use a microscope to look for chromosomal abnormalities that are associated with autism, explained Dr. David Miller, a clinical geneticist and assistant director of the Genetics Diagnostic Laboratory at Children's Hospital Boston, which conducted the new research along with Boston's Autism Consortium. Medlogs - Recent stories
It is chromosomally different from the mother and father. Misconception
These exposed populations have been shown to have chromosomal damage.
But a new procedure called cytoplasmic transfer may soon help women whose eggs are, according to a microscopic examination, chromosomally or structurally fragile and therefore may fail to implant or grow. The Infertility Challenge
Emory University School of Medicine offers a new method of genetic testing called chromosomal microarrays that can pick up chromosomal abnormalities across the genome based on analysis of a blood sample, said David Ledbetter, director of the school's medical-genetics department. Gene-Patent Licenses Could Hurt Research, Study Says
Most of what goes wrong during meiosis-to-fertilization-to-mitosis results in chromosomal abnormalities, usually nondisjunction, thus providing a mechanism for aneuplodiy -- rather than an insistence that it really does happen. WN.com - Articles related to Plants give up some deep secrets of drought resistance
A common type of chromosomal abnormality is called a trisomy.
Amniocentesis is performed for viral cultures, chromosomal analysis and alpha-fetoprotein levels. Hydrocephalus
Although Belinda was 37, she decided against amniocentesis or any other test to detect chromosomal abnormalities.
Unlike the retrovirus, adenoviral DNA functions in an extrachromosomal manner.
Of all the chromosomal aberrations, the appearance of asynapitc univalent and resultant pollen abortion was the major cause of seedless fruits.
When their computer identified a chromosome with an unusual banding pattern, the researchers chalked up an intrachromosomal aberration.
Mitochondrial Eve is the female counterpart of the Y - chromosomal Adam, the patrilinear most recent common ancestor.
From 6 to 26 nucleotide repeats have been identified in the chromosomal ends of Protozoa, fungi, nematodes, plants, and vertebrates.
Basic questions such as the chromosomal evolution or the phylogeny of these living fossils are still unresolved.
The derivation of our model centers on tetraploid species in which multivalent pairing is only one mechanism for chromosomal pairings during meioses.
Lines below the chromosomal map indicate the deleted region with the arrow pointing in the direction of the deletion.
The main objective of our study was to identify chromosomal regions possibly containing putative disease loci involved in the etiology of anal atresia.
Cytogenetic damage, evaluated as chromosomal aberrations, has been successfully applied as a reliable biomarker for chronic health risk.
First-trimester screening also can help detect other chromosomal abnormalities such as trisomy 18.
Major chromosomal rearrangements are often found in transformed genomes, suggesting that T-DNA insertion either requires or causes genomic instability.
Even if there are âintelligenceâ genes, they are not going to travel (chromosomally) with a non-existent race gene, and very very unlikely to travel with a gene like melanin-production (empirical question ... although I think this too has been answered with genetic epidemiology studies about interâ and intra-continental variance). The Volokh Conspiracy » 1. Science, Faith, and Not Ruling Out Possibilities
Mitochondrial Eve is the female counterpart of the Y - chromosomal Adam, the patrilinear most recent common ancestor.
View larger image » If the serial fetal bladder drainages for urinary electrolytes and protein components come back favorable and if there is a recent history of decreased to no amniotic fluid (oligohydramnios, anhydramnios) and no chromosomal abnormalities in a male fetus, the family may be offered fetal intervention with a vesicoamniotic shunt placement or fetal cystoscopy to further evaluate the source of fetal urinary tract obstruction. Lower Urinary Tract Obstruction (LUTO)
Ectopic crossing over causes chromosomal abnormalities, including deletions, translocations, and acentric and dicentric chromosomes.
To be sonned by Rick Sanchez takes a certain chromosomal abundance. They Calling You A Bitch Not A Bandit At Your Wake | ATTACKERMAN
Autosomal genes often showed deranged regulatory levels, indicating they were in pathways perturbed by X chromosomal changes.
Anopheline mosquitoes, like Drosophila, are renowned for the presence of polytene chromosomes and chromosomal inversions.
Broadening the range of manipulatable DNA to megabase scale would be fundamental to deepen the understanding of gene regulation in the chromosomal context. PLoS ONE Alerts: New Articles
As reported previously, at each insertion site some chromosomal DNA was deleted, most likely in conjunction with the integration event.
He refused to accept ideas associating the gene with a particular stretch of chromosomal material.
The aim of this study was to characterize the molecular basis of the oncogenicity of CH-ES1 cells, we looked for abnormal chromosomal copy number (by array Comparative Genomic Hybridization, aCGH) and single nucleotide polymorphisms (SNPs). PLoS ONE Alerts: New Articles
He knew that, on average, about six births in a thousand involved some form of chromosomal abnormality. GRACE
One type of DNA called chromosomal DNA, also refered as nuclear DNA. CNN Transcript Oct 30, 2003
Their presence in cells is a reflection of structural and/or numerical chromosomal aberrations arising during mitosis.
However, the observed differences may be conditional on the chromosomal location of the chiasmata.
Some humans are born "intersexed," i.e.: born with chromosomal or other biological characteristics of both male and female. TEXAS FAITH: Why should science talk to religion? | RELIGION Blog | dallasnews.com
Further, in most organisms there is a virtual absence of exchange in heterochromatin and a reduction of exchange frequencies in euchromatin that lies near chromosomal elements such as centromeres and telomeres.
Moreover, the susceptibility to high recombination is preserved even if the specific region is translocated to a new chromosomal position.
However, we observed that a fraction of survivors become uracil auxotrophs, because of repair events associated with more complex chromosomal rearrangements.
Prenatal diagnosis for the detection of chromosomal abnormalities was carried out by conventional cytogenetics in the present study in the foetuses of high risk pregnancies in women attending a tertiary care facility in north India.
Physical intersexes are rare but do occur, and there are also cases in which chromosomal sex is different from phenotypical sex.
Your discoveries have revealed how the conserved function of telomere repeat sequences can maintain chromosomal and genetic stability and how synthesis of telomere DNA is achieved by the enzyme telomerase. The 2009 Nobel Prize in Physiology or Medicine - Presentation Speech

How To Use Chromosomal In A Sentence

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