NOUN
- any change in the normal structure or number of chromosomes; often results in physical or mental abnormalities
How To Use chromosomal aberration In A Sentence
- For example, acesulfame-K induces chromosomal aberrations; sucralose is associated with several effects in animals, is weakly mutagenic, and increases the glycosylated hemoglobin in diabetic patients.
- The type of chromosomal aberrations detected in the azoospermic and oligozoospermic men are given in Table I.
- Conventional cytogenetics is a validated technique to study the acquired gross chromosomal aberrations associated with human cancer.
- No significant increase in cells with chromosomal aberrations, polyploidy or endoreduplication was observed at the concentrations analyzed.
- This cell line detects a wide variety of mutagenic lesions, including point mutations, deletions and various types of chromosomal aberrations.
- The number of cells with chromosomal aberrations among 100 well-spread metaphases was recorded.
- These effects include the induction of chromosomal aberrations and sister chromatid exchange.
- I started to work eagerly on the induction of specific chromosomal aberrations in adenovirus type 12-infected human cells, simultaneously studying a DNA-replication disturbance of individual chromosomes in human lymphoblastoid and lymphoma cell lines, and, to please my mentor, I demonstrated electron microscopically the presence of EBV particles directly in individual serologically antigen-positive Burkitt's lymphoma cells. Harald zur Hausen - Autobiography
- Of all the chromosomal aberrations, the appearance of asynapitc univalent and resultant pollen abortion was the major cause of seedless fruits.
- When their computer identified a chromosome with an unusual banding pattern, the researchers chalked up an intrachromosomal aberration.