How To Use Cholinesterase In A Sentence
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Most work by blocking acetylcholinesterase, an enzyme vital for nerve function.
Times, Sunday Times
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Fleisher JH, Harris LW, Murtha EF (1967) Reactivation by pyridinium aldoxime methochloride (PAM) of inhibited cholinesterase activity in dogs after poisoning with pinacolyl methylphosphonofluoridate (soman).
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In experiments with the new material it defended completely against Staph and E. Coli infections and within 24 hoursit restored 70% of acetylcholinesterase — a bodily enzyme that is attacked by nerve agents.
Combating Terrorism with an Environmentally Friendly Polymer | Inhabitat
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Memantine is intended to treat moderate to severe Alzheimer's, but it is frequently used in mild Alzheimer's patients "off-label" - for uses other than those approved by the Federal Drug Administration - either alone or in combination with a drug known as a cholinesterase inhibitor.
The Globe and Mail - Home RSS feed
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Janda said, "we found that thc was a very effective inhibitor of acetylcholinesterase. in addition to propidium, we also found that thc was considerably more effective than two of the approved drugs for alzheimer's disease treatment, donepezil (aricept ®) and tacrine (cognex
Aids-write.org
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The cholinesterase inhibitor tacrine is used rarely because of potential liver toxicity and the need for frequent laboratory monitoring.
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When it has finished transmitting its messages, it is broken up by an enzyme, acetylcholinesterase.
Times, Sunday Times
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New study finds that older people hospitalized for bradycardia are more likely to be taking cholinesterase-inhibiting drugs such as donepezil People taking one of several drugs commonly prescribed to treat
WN.com - Articles related to Lyme disease debate rages on
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In someone with Alzheimer's, cholinesterase breaks down and destroys acetylcholine, the neurotransmitter chemical.
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Most modern synthetic organophosphorus compounds are tailor-made to inhibit acetylcholinesterase, an enzyme essential for life in humans and other animal species.
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The use of antidepressants, antipsychotics, or anticholinesterase inhibitors for insomnia related to delirium or dementia is also unproved.
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To test whether different acetylcholinesterase activity accounts for the sex differences in nicotinic currents, we probed nicotinic currents using carbachol, a nicotinic receptor agonist that is not broken down by endogenous acetylcholinesterase.
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And some research suggests that the drugs—memantine (Namenda), and cholinesterase inhibitors such as donepezil (Aricept and generic) and galantamine (Razadyne and generic)—may be more effective when taken together.
Brain boosters in a bottle?
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Organophosphate and carbamates are nerve poisons that lower the blood levels of an enzyme called cholinesterase, which aids in the regulation of the nervous system.
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By inhibiting cholinesterase, more acetylcholine is available for normal memory-related and cognitive functioning.
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As an anticholinesterase, Mev also elicits cardiac depression by a vagomimetic action on the heart via accumulation of acetylcholine.
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A mainstay of treatment for Alzheimer's is a class of drugs called the cholinesterase inhibitors.
BBC News | News Front Page | World Edition
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In both, males and females, the inward current persists longer after carbachol compared to acetylcholine, since the acetylcholinesterase in the brain slice metabolizes applied acetylcholine allowing the cell to return to baseline faster.
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Once released, ACh must be removed rapidly in order to allow repolarization to take place; this step, hydrolysis, is carried out by the enzyme, acetylcholinesterase.
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Correlation of electrophysiology with pathology, pathogenesis and anticholinesterase therapy in post-polio syndrome.
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Decreased libido and impaired ejaculation also may occur; they can be treated with dose reduction or a peripheral cholinesterase inhibitor neostigmine, 7.5-15 mg at 30 to 60 minutes prior to intercourse.
The Neuropsychiatric Guide to Modern Everyday Psychiatry
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Repeat exposure results in accumulation and increasing inhibition of the key enzyme acetylcholinesterase.
Times, Sunday Times
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Fortunately, nerves contain an enzyme called cholinesterase (koh'lin-es'tur-ays) which brings about the breakup of acetylcholine to acetic acid and choline once more.
The Human Brain
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All nerve agents act by inhibiting the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine.
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I can tell you how an enzyme called acetylcholinesterase works but I can't tell you how to properly use present participles.
Reasoned School Reform
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The use of antidepressants, antipsychotics, or anticholinesterase inhibitors for insomnia related to delirium or dementia is also unproved.
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Whether or not the toxin used in the IDF attacks was a known nerve gas, the evidence strongly suggests that it was a potent anticholinesterase poison -- a nerve gas by any other name. (see sidebar,
WHAT REALLY HAPPENED
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The main clinical features of striated muscle is local or systemic weakness in the activities easy to fatigue by rest or with anti-cholinesterase drugs can be mitigated.
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In someone with Alzheimer's, cholinesterase breaks down and destroys acetylcholine, the neurotransmitter chemical.
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Patients with concomitant disease were included if their conditions were controlled, but patients with neurodegenerative conditions and those who had already received cholinesterase inhibitor therapy were excluded.
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Both teas inhibited the activity of the enzyme acetylcholinesterase, which breaks down the chemical messenger, or neurotransmitter, acetylcholine.
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The UN team concluded from them that the patients had been exposed to an anticholinesterase agent "- nerve gas. (
WHAT REALLY HAPPENED
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All nerve agents act by inhibiting the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine.
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This neurotoxic action kills bugs by reducing the level of a certain enzyme (acetylcholinesterase) that clears an important neurotransmitter chemical (acetylcholine) out of the junction between nerve cells.
Dr. Walter Crinnion: Could Organic Produce Be the New Ritalin?
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Blood - Determination of cholinesterase activity - Spectrophotometric method - Acetylthiocholine and dithio - bis - ( nitrobenzoic acid ) method.
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Sage oil inhibits an enzyme called acetylcholinesterase, whose normal job is to break down the chemical messenger acetylcholine.
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And some research suggests that the drugs — memantine (Namenda), and cholinesterase inhibitors such as donepezil (Aricept and generic) and galantamine (Razadyne and generic) — may be more effective when taken together.
Brain boosters in a bottle?
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The sex difference persisted when the nicotinic receptors were activated with carbachol, an analogue of acetylcholine that is not broken down by endogenous acetylcholinesterase.
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Cholinesterase inhibitors, which reduce cholinesterase - the enzyme that breaks down acetylcholine - are the only FDA-approved treatment for Alzheimer's.
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Researches also show that Epimedium can inhibit an enzyme called acetylcholinesterase
Xml's Blinklist.com
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Tim Foley Alzheimer's disease is often treated by a class of drugs called cholinesterase inhibitors, which help boost levels of a brain chemical called acetylcholine.
Drug Cocktail May Slow Alzheimer's
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Normally, at these nicotinic synapses, the transmitter is rapidly destroyed by the enzyme cholinesterase, so its action is evanescent; this is not the case with nicotine.
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In the study, it was found that DEET blocked the enzyme cholinesterase, which is essential for transmitting messages from the brain to the muscles, in experiments done on rodents using an amount of DEET equivalent to that used by humans.
Livescience.com
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Enzyme kinetics investigation revealed that the affinity of gut carboxylesterase of Periplaneta americana (L. ) for dipterex was 23 times greater than that with the cholinesterase.
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Whereas the anticholinesterase compounds, which have high acute toxicity (and hence are highly hazardous to the applicator), are readily and rapidly degraded in nature, the halogenated hydrocarbons are not.
Rachel Carson’s Victims, R.I.P.
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An early favorite target was the vital enzyme acetylcholinesterase, required for hydrolysis of acetylcholine at neuromuscular junctions, and it has been exploited by agrochemical companies in a spectacular manner.
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Anticholinesterase drugs stimulate nerve-impulse transmission, and corticosteroids may help.
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The pseudocholinesterase activity after adsorption was almost 3 fold compared with before adsorption.
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Bacq and Brown22 have more recently extended these observations to a series on artificial eserine analogues, and have found that the potentiating action on the response of mammalian muscle to single nerve volleys is, in fact, proportional, in the different compounds of the series, to the anticholinesterase action, as independently determined.
Sir Henry Dale - Nobel Lecture
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If the memory loss is severe enough to warrant a diagnosis of dementia, then cholinesterase inhibitor therapy would be indicated.
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All nerve agents act by inhibiting the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine.
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In the absence of acetylcholinesterase, levels of the transmitter acetylcholine increase.
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Amniotic fluid acetylcholinesterase is found in gastroschisis but not omphalocele.
CHOP abdominal wall defect publications
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Available cholinesterase inhibitors drugs are donepezil, galantamine, rivastigmine, and tacrine. antipsychotic agents (olanzapine, quetiapine, risperidone), were found to have "adverse effects offset advantages in the efficacy of atypical antipsychotic drugs for the treatment of psychosis, aggression, or agitation in patients with Alzheimer's disease.
Citizendium, the Citizens' Compendium - Recent changes [en]
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The suspect compounds, known as cholinesterase inhibitors, aren't normally toxic at low levels.
Poisoned In The Gulf?
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THC has been found to prevent an enzyme called "acetylcholinesterase" from producing Alzheimer's plaques in the brain and is found to be effective in blocking protein clumps that inhibits memory and cognitive thinking in Alzheimer's patients.
Vault9.net
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Hornberg A, Tunemalm AK, Ekstrom F (2007) Crystal structures of acetylcholinesterase in complex with organophosphorus compounds suggest that the acyl pocket modulates the aging reaction by precluding the formation of the trigonal bipyramidal transition state.
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Currently, a class of drugs called cholinesterase inhibitors are widely used to treat Alzheimer's patients,
Medlogs - Recent stories
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Positive or faint amniotic fluid acetylcholinesterase band with normal ultrasound.
Prenatal Diagnosis
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The nerve gases that have been developed for warfare are known as "anticholinesterase agents.
WHAT REALLY HAPPENED
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Largely because the anticholinesterase nerve agents produce a unique and striking pattern of symptoms.
WHAT REALLY HAPPENED
