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How To Use Caspase In A Sentence

  • Janzen et al have shown that caspase-3 null mice harbour long term hematopoietic stem cells to a higher extent compared to the wild type animal PLoS ONE Alerts: New Articles
  • Scientists exposed genetically engineered mice to a drug that activates a molecule called caspase 8 that kills senescent cells. The Full Feed from HuffingtonPost.com
  • They have discovered that the novel effect of caspase 3 in stem cells is related to its ability to activate another protein that cuts up the cell's DNA (called caspase-activated DNase) and has also traditionally been associated with programmed cell death. PhysOrg.com - latest science and technology news stories
  • Thus we sought to assess the role of cell permeable inhibitors of cysteine proteases; caspase (zVADfmk) and calpain (zLLYfmk) as supplements in the serum free culture of CD34 PLoS ONE Alerts: New Articles
  • Moreover, pro - caspase 3 was hydrolyzed and activated in DATS - treated MGC 803 cells.
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  • The study, published today in the Journal Nature, used mice that were genetically engineered with deadbeat cells that carry a molecule, called caspase 8. BusinessWeek.com -- Top News
  • He works primarily with caspase-1, which works far upstream in the apoptotic processing pathway. The Scientist
  • Cells treated with H35N (a mutant of α-HL that remains as membrane bound monomer), have been shown to accumulate hypodiploid nuclei, activate caspases and induce intrinsic mitochondrial apoptotic pathway. Elites TV
  • CAD (or caspase-activated DNase in full) by slicing apart other proteins holding it at bay. ScienceBlogs Channel : Life Science
  • In the cancer study, researchers identified a key sequence of amino acids-arginine, glycine, and aspartic acid, (the RGD motif) - that triggered the death of leukaemia cells by activating a protein called caspase-3. Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7
  • The "extrinsic" pathway involves transmembrane, extracellular receptor-dependent activation of caspase-8 (and possibly -10). The Scientist
  • This kit allows for continuous monitoring of caspase activity. The Scientist
  • Caspases exist as inactive proenzymes which undergo proteolytic processing by upstream caspases (caspase-8, -9) at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme in the form of WN.com - Articles related to DTI favors zero tariffs on cement, wheat
  • They have discovered that the novel effect of caspase 3 in stem cells is related to its ability to activate another protein that cuts up the cell's DNA (called caspase-activated DNase) and has also traditionally been associated with programmed cell death. PhysOrg.com - latest science and technology news stories
  • All caspases, which are initially inactive proenzymes, share the same processing scheme to achieve mature forms after cleavage at specific Asp sites.
  • They found that the molecule called caspase, which was already well known for killing cells, could be used to target specific cancerous ones. Medindia Health News
  • The morphological and biochemical changes typical of apoptosis are orchestrated by caspases, a family of cysteine proteinases, which cleave proteins after aspartate residue.
  • Fluorescence of the lysed cellular supernatants in the ApoAlert caspase profiling plates was read in a microplate fluorometer, by use of excitation and emission wavelengths of 380 and PLoS ONE Alerts: New Articles
  • The role of two cysteine proteases; caspase and calpain has been highly implicated in programmed cell death in many cell systems PLoS ONE Alerts: New Articles
  • In the new study, Xue and his team found that a well-known cellular molecule called caspase PhysOrg.com - latest science and technology news stories
  • These findings suggest that dcp-1 activity is required for the proper subcellular localization of active caspases.
  • Users can view labeled caspases under a fluorescence microscope or analyze them with a flow cytometer or fluorescence plate reader. The Scientist
  • The apoptotic death signal is transmitted by caspases, a small family of proteases. The Scientist
  • Neutrophils from healthy volunteers were incubated with DFP (2.5 mM), and neutrophil elastase (NE) activity; hypodiploid DNA formation; caspases-3 and -8 processing and activity; exteriorization of phosphatidylserine (PS); oxidative burst activity and hydrogen peroxide release were measured. BioMed Central - Latest articles
  • Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. WN.com - Articles related to DTI favors zero tariffs on cement, wheat
  • Neutrophils from healthy volunteers were incubated with DFP (2.5 mM), and neutrophil elastase (NE) activity; hypodiploid DNA formation; caspases-3 and -8 processing and activity; exteriorization of phosphatidylserine (PS); oxidative burst activity and hydrogen peroxide release were measured. BioMed Central - Latest articles
  • Apoptosis modulators such as caspase inhibitors might one day come close to curing acute brain injury. The Scientist
  • Xu YA, Gada H, Guttmann RP, Siman R (2003) Cross-talk between calpain and caspase proteolytic systems during neuronal apoptosis. PLoS ONE Alerts: New Articles
  • The short prodomains caspases induced cell apoptosis, which played an effector as a target protein of cytosol or nucleus.
  • The "extrinsic" pathway involves transmembrane, extracellular receptor-dependent activation of caspase-8 (and possibly -10). The Scientist
  • This kit contains the necessary reagents to measure apoptosis by flow cytometry based on the presence of active caspase-3. The Scientist
  • Numerous studies have shown that many kinds of cancer cells overproduce this caspase inhibitor, apparently to stymie the cellular-suicide program called apoptosis.
  • The mitochondria gradually swells, and eventually the outer membrane ruptures, releasing caspase-activating proteins into the cytosol. [10,32]
  • Once activated, caspase-3 is a marker for cells undergoing apoptosis. The Scientist
  • We further observed that both the caspase and calpain inhibitors reduced the activation of caspases with an equal efficiency. PLoS ONE Alerts: New Articles
  • When they blocked or removed a key death-promoting protein called caspase 3, they found that stem cells stopped producing new muscle fibres. Innovations-report
  • He works primarily with caspase-1, which works far upstream in the apoptotic processing pathway. The Scientist
  • This kit contains the necessary reagents to measure apoptosis by flow cytometry based on the presence of active caspase-3. The Scientist

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