How To Use Carcinogenic In A Sentence
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For example, it was claimed that the study presented uniquely reliable evidence that simvastatin is not carcinogenic.
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the carcinogenic action of certain chemicals
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Actual results may differ materially from those set forth in this release due to the risks and uncertainties inherent in Somaxon's business, including, without limitation, Somaxon's interpretation of its communications and interactions with the FDA relating to the requirements for approval of the NDA for Silenor, and the FDA's agreement with such interpretation; Somaxon's interpretation of the results of the clinical trials for Silenor, the timing of the interpretation of such results and the FDA's agreement with such interpretation; the potential for Somaxon to make a resubmission to the Silenor NDA; the potential for Silenor to receive regulatory approval for one or more indications on a timely basis or at all; the potential for the FDA to impose non-clinical, clinical or other requirements to be completed before or after regulatory approval of Silenor; Somaxon's ability to demonstrate to the satisfaction of the FDA that potential NDA approval of Silenor is appropriate prior to the completion of standard, long-term carcinogenicity studies, given the context of completed trials and pending studies; the timing and results of non-clinical studies for Silenor, and the FDA's agreement with Somaxon's interpretation of such results;
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In rat liver, it has been shown that tamoxifen forms covalent DNA adducts, implying a genotoxic mechanism for its carcinogenicity in this tissue.
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Teratogenicity and carcinogenicity can result from biochemical toxicity.
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Conclusion MTBE′s carcinogenicity to animals may relate to induction of cell proliferation and inhibition of cell apoptosis.
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Both tobacco and cannabis have a similar range of carcinogenic substances.
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The air looked sweet and noncarcinogenic on the spectrograph.
A Hole In Space
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However, because of its lower combustibility it contains 50% more carcinogenic polycyclic aromatic hydrocarbons including naphthalene, benzanthracene, and benzopyrene, than tobacco smoke.
Impact Lab
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All plants produce their own toxins or they wouldn't survive predators, and as noted by eminent University of California biologist Bruce Ames, a high proportion – about half – of these toxins tested in animal cancer bioassays are carcinogenic.
Turning gene science into a fishy business
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Standards for noncarcinogenic chemicals, for instance, are defined by the maximum dose that causes no harm to animals in a toxicity study, divided by numerical factors to reflect data uncertainties.
Toxicity testing- new dimensions
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They've got a carcinogenic potential and the potential to suppress the immune system.
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It has since been discovered that these materials were not suitable for use, containing a number of contaminants, including carcinogenic chemicals.
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There is no ventilation system that reduces or eliminates the carcinogenic products of second-hand smoke or the sidestream smoke from cigarette smoking.
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Several agricultural innovations like 2,4-D weed spray and diethyl stilbestrol for cattle feeding were banned by federal agencies because of their carcinogenic consequences.
Diffusion of Innovations
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He's spent a fair bit of his career describing how carcinogenic the sun is.
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Using daily dosages equivalent to the threshold dose for erythema production in untanned human skin, he found that the peak carcinogenic response occurred at 310 nm.
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During this period she published no fewer than ten books and articles in her field-the relationship between chemical structure and carcinogenicity.
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As published in the Feb. 25, 2011 Science Insider editorial, "Advancing Regulatory Science," FDA Commissioner Dr. Hamburg claimed that FDA's regulations must be based on "better predictive models -- functional genomics, proteomics, and metabolomics," rather than "high dose animal carcinogenicity studies -- unchanged for decades.
Samuel S. Epstein: Multiple Carcinogens in Johnson & Johnson's Baby Shampoo
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In favorable conditions, these fungi can infect crops such as corn, cottonseed, wheat, or peanuts, producing toxins that can cause serious illness in livestock and may be carcinogenic to humans.
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HEALY: Well you know, the very highly -- the charred is the concern, that charcoal that you take into your system, if you regularly eat a lot of charcoal broiled meat, there is a concern that you're taking in things that have been shown to be carcinogenic.
CNN Transcript Apr 1, 2007
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In this study by IARC, other known carcinogenic substances in solid wood were not identified.
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Its always nice to read well meaning NONSENSE such as that posted above by “Blue Jeans Baby » Comfortable Castle – Improving your home » Blog Archive” as they perpetuate the FALSE MYTH that fiberglass is carcinogenic.
RECYCLED BLUE JEAN INSULATION by Bonded Logic | Inhabitat
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Some traditional herbal products display known toxicities (e.g., calamus, comfrey, and sassafras all have been shown to have carcinogenic actions).
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Many studies strongly support the premise that oxidative stress plays an important role in this carcinogenic process.
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The researchers plan to test their screening technique to find microbes that break down carcinogenic chemicals at coal tar waste sites.
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Our study has shown that aspartame is a multipotential carcinogenic compound whose carcinogenic effects are also evident at a daily dose of 20 milligrams per kilogram of body weight mg/kg, notably less than the current acceptable daily intake for humans.
Flawed aspartame study | The Blog of Michael R. Eades, M.D.
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What could be wrong with this non-carcinogenic, non-resource-wasting joy?
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They have also stated that cannabis is in fact less addictive, and less carcinogenic than the tobacco used to roll the joints.
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It has been shown to be teratogenic and carcinogenic in rodents.
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This required a method any case, one Company, supposedly laudibly, to establish carcinogenicity, which is now an impor - searched for a nonalcoholic solution for their sulfo - tant element in the toxicology package for an over - namide.
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A medium-term liver bioassay for carcinogens can be used for detecting the effect of chemical mixtures at low dose levels, as well as detection of the carcinogenic potential of individual test chemicals.
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Derivatives of cinnamic aldehyde can now be used to protect cells from carcinogenic and other toxic agents.
Forever Young
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Fracking uses carcinogenic and neurotoxic chemicals, active at parts per trillion, according Dr. Theo Colborn, and other health experts.
Alison Rose Levy: Water or Gas? Karl Rove, Cheney, and Cohorts Weighing In On Key NY Race
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This highlights the carcinogenic potential of AA in human beings.
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Under this process, information about the proposed use of a noncarcinogenic substance that results in a dietary concentration that does not exceed the threshold would undergo an abbreviated review by FDA, as opposed to the extensive review and formal issuance of a regulation normally required for food additives.
Statement On The Regulation Of Food Additives Before The U.S. House Subcommittee On Human Resources And Intergovernmental Relations
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This may be caused by carcinogenic additives to lead-free petrol such as benzene.
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We focus on three sets of substances: those which were regulated as carcinogens by OSHA in the Standard, those which were included in the Standard but whose exposure limits are based on noncarcinogenic effects, and those substances designated as potential carcinogens by NIOSH, ACGIH, and/or NTP but which were excluded from the Standard.
Georgianne Nienaber: Media Contributes to Victim Mentality as Gulf Struggles
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Apart from their well known carcinogenic action on the liver, they also impair growth and the development of the immune system in children.
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Likewise, the carcinogenic action of bile may be related to the duration of exposure of gastric mucosa to biliary carcinogens.
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Tobacco is a sweet smelling product of the aromatic leaves of the Nicotina plant, but contains carcinogenic and highly addictive substances like nicotine, tar and benzene.
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But even more important is that it absorbs carcinogenic ultra-violet rays and electromagnetic radiation.
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Give any large areas a squirt of zinc chromate primer but beware - it is very toxic and carcinogenic.
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As Straw points out, even toys can be dangerous, using as an example the rawhide chews many dogs are so fond of; the hides are preserved and cured with chemicals that can be carcinogenic.
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Crabs, for example, when examined, show up to 20 times the normal levels of carcinogenic metals such as cadmium and cobalt.
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Pollutants in diesel exhausts exist as particles or gas phase compounds and the contribution of nitrated, oxygenated and alkylated PAHs to the mutagenic and carcinogenic activity has been recognized.
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The disease has taken hold after the only treatment - sodium arsenite - was banned because it is carcinogenic.
Times, Sunday Times
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The carcinogenic effect of diesel exhaust exposure is mainly ascribed to the inhalation of particles.
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When women's ovaries stop producing estrogen, he said, the body tries to compensate with an enzyme called aromatase, which converts testosterone into a carcinogenic form of estrogen in fat tissue.
Yahoo! News: Business - Opinion
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But we know better: worse than leaving work in smelly clothes is the full shift spent working in the presence of a carcinogenic environmental constant.
Smoke Gets in Your Eyes
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But environment watchdogs said that residents have not been put at risk by a complex operation to remove chemicals including tar, cyanide, ammonia and carcinogenic coal naptha.
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Here I am, asprawl upon one of those cheap couches they send to you in two or three boxes for self-assembly; they are unstable and a carcinogenic perfume wafts from the cushions.
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One of the principal mechanisms of the anticarcinogenic activity of tea is inhibition of the initiation stage of carcinogenesis.
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Airline pilots are occupationally exposed to cosmic radiation and other potentially carcinogenic elements.
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For example, many metals, like cadmium, lead, and mercury are toxic to humans and are mutagenic and carcinogenic.
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These data demonstrated for the first time that aspartame is a carcinogenic agent, inducing various types of malignant tumors in rats, even at dose levels currently considered acceptable for humans.
Archive 2007-04-01
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Heat-treated oils go rancid - in other words, they spoil - and rancid oils are carcinogenic.
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The exhaust will also have to be fitted with filters to trap the particulates and their carcinogenic PAHs.
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These new substances have often not been tested for toxic effects, such as neurotoxicity, carcinogenicity or birth defects.
Latest news from the public and voluntary sectors, including health, children, local government and social care, plus SocietyGuardian jobs | guardian.co.uk
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Beta carotene, a provitamin found in plants and their pigments, is a benign source of vitamin A and is an antioxidant with possible anticarcinogenic properties.
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First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague
Alcohol
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There aren't a lot of good in vitro methods to predict carcinogenic potential.
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`Keep well clear of that wood-fire smoke,' whispered Pete to Joe, `it's carcinogenic.
THE PRESIDENT'S CHILD
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He was also dragged into a public controversy over the carcinogenic effects of low-level radiation.
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Artery-clogging cholesterol, alcohol and carcinogenic free radicals cause cellular mayhem in the aftermath of too many bibulous feasts.
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Don't sugar-coat: they may have declared Nutra-sweet non-carcinogenic, but it still has that saccharine aftertaste.
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Emergency action has been taken by the European Parliament's Committee on Food to stop the UK importing products known to contain this carcinogenic colouring.
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Some of them are carcinogenic, and some of them also cause neurological and reproductive health problems.
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These results suggested that EBV infection of oral squamous epithelium might take part in carcinogenic or development of oral squamocellular carcinoma.
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But Lakretz says this new approach to disinfecting water while controlling biofouling can also reduce the amount of carcinogenic by-products that chlorine produces.
PhysOrg.com - latest science and technology news stories
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In October 1993, FDA proposed this policy, which establishes a process for determining when the likelihood or extent of migration to food of a noncarcinogenic substance used in packaging is so trivial as not to require regulation of the substance as a food additive.
Statement On The Regulation Of Food Additives Before The U.S. House Subcommittee On Human Resources And Intergovernmental Relations
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She worked with lethal material and was diagnosed with a brain tumour, probably caused by the carcinogenic fumes wafting around her studio.
September 2008
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Up until the late 1980s, carcinogenic asbestos was used in building houses.
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Church air was found to be considerably higher in carcinogenic polycyclic hydrocarbons than air beside roads travelled by 45,000 vehicles daily.
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Isoflavone phytoestrogens such as genistein from soy and certain lignan phytoestrogens may protect against the possible carcinogenic actions of estrogen by:
Forever Young
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The exhaust will also have to be fitted with filters to trap the particulates and their carcinogenic PAHs.
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This is hardly surprising: the two most carcinogenic compounds ever detected are produced by diesel engines.
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We selected five compounds, genistein, metaproterenol, rotenone, p-anisidine and resorcinol, that had extensive genotoxicity and carcinogenicity data and tested them in the standard 7 day exposure SHE assay.
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No credible evidence was found that aspartame is carcinogenic, neurotoxic or has or any other adverse effects when consumed even at levels many times the established ADI levels.
Aspartame Deemed Safe by Expert Panel? | Impact Lab
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The artist is quick to point out than the paint he uses is non-toxic, non - radioactive and non-carcinogenic.
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The results of this carcinogenicity bioassay not only confirm, but also reinforce the first experimental demonstration of aspartame's multipotential carcinogenicity at a dose level close to the acceptable daily intake ADI for humans.
Archive 2007-06-01
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For example, chlorinated drinking water disinfectants react with naturally occurring bromides in oceans and lakes to form compounds that are much more carcinogenic than the original disinfectant.
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There are three carcinogenic ingredients in Johnson & Johnson's Baby Shampoo, dioxane, formaldehyde and nitrosamine.
Samuel S. Epstein: Multiple Carcinogens in Johnson & Johnson's Baby Shampoo
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A dye called Malachite green, used to treat fungus on fish, is carcinogenic.
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What was once our sustenance has become carcinogenic and devoid of goodness and nourishment.
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While bromate is potentially carcinogenic, a spokeswoman for Coca-Cola stressed that there was no health risk from drinking bottles of Dasani.
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My lungs feel awful, bloated repositories of carcinogenic gunk, and for what?
LOVE YOU MADLY
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Despite evidence of the carcinogenic properties of pesticides, aerial spraying remains widespread.
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Many chemotherapy treatment regimes, not least those that include methylating agents, are carcinogenic in patients surviving long term.
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Made from mechanically processed meat (some of it containing recycled pet food and banned carcinogenic antibiotics), they are bound together with polyphosphates and gums.
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The World Health Organization has concluded that cannabis, when smoked, is twice as carcinogenic as tobacco.
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She chomped on the cigar, and seething, she inhaled sharply and spewed a jet-stream of carcinogenic smoke into the acrid atmosphere between them.
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One family of mycotoxins, the aflatoxins, are carcinogenic and immunotoxic and cause growth retardation in animals.
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But cooking muscle meats and other protein foods at high heats can create carcinogenic chemicals called heterocyclic amines (HCAs).
Dr. Nicholas Perricone: Barbecue Your Way to Beautiful Skin
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Regulators recently issued warnings about herbal products containing aristolochia, a banned toxic and carcinogenic plant derivative.
Times, Sunday Times
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Primarily the volatile haloforms such as chloroform, but also dichlorobromomethane, chlorodibromomethane and bromoforme, are suspected of being harmful to health, some even carcinogenic.
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Interaction between metabolites of chemical carcinogens, such as polycyclic aromatic hydrocarbons, and DNA can cause mutation in oncogenes and tumor suppressor genes which is believed to initiate the carcinogenic process.
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* disclaimer: depending on your use of the term carcinogen and how far you want to take it then yes, all air is carcinogenic and pretty much every item you come in contact with is carcinogenic as well.
Original Signal - Transmitting Digg
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Conclusions regarding carcinogenicity in humans or experimental animals are based on expert, scientific judgment, with consideration given to all relevant information.
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Arsenic is a known human carcinogen in adults, yet its carcinogenicity in children remains uninvestigated.
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Acsh, which had assets of $1.8 million in 1998, made its first headlines by refuting the dangers of the potentially carcinogenic growth hormone Alar, which was widely sprayed on apples to keep them on the tree longer.
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However, a phytonutrient called diallyl sulfide DAS, one of the sulfide compounds that give garlic its characteristic smell, can inhibit the carcinogenic effects of PhIP.
The Fiber35 Diet
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Researchers study effects of unidentified products that are highly-contaminated with residues of carbamate, organophosphate and chlorine pesticides, dioxin in the smoke from the chlorine pesticides and bleached paper, cancer-causing polonium 210 radiation from certain phosphate fertilizers, any of about 1400 untested and often toxic non-tobacco additives, added burn accelerants, kid-attracting sweets and flavorings etc, carcinogenic filter components, and addiction-enhancing additives.
Pesticide Industry War On Mothers
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Cooking red meats at high heats produces carcinogenic chemicals linked to the disease.
The Sun
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The use of sprays can lead to an indoor build-up of large quantities of carcinogenic vapours.
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Vitamin C is an antioxidant, and it also inhibits the formation of carcinogenic nitrosamines from dietary amines and nitrites.
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The authors said the results confirmed and reinforced their first experimental demonstration of aspartame's multipotential carcinogenicity at a dose level close to the human ADI.
ConfectioneryNews RSS
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The numbers might not add up because some chemicals fit into more than one category, for example, they might be carcinogenic and be suspected respiratory toxicants.
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50% of the 170 compounds were judged to be carcinogenic, but some of these might be false positives.
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They say a science based testing regime would include long term animal feeding trials with the whole genetically modified crop to test for carcinogenic, reproductive and other adverse effects.
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However, some studies also focused on the mechanisms by which particles without organic pollutants cause carcinogenic effects.
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Immunofort is indicated also as coadjutant treatment in patients with cancer, raising the natural defenses of the organism to combat cancerous cells and diminishing the side effects of conventional anticarcinogenic treatments.
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Emergency action has been taken by the European Parliament's Committee on Food to stop the UK importing products known to contain this carcinogenic colouring.
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What is more, chemical tear gas lachrymators are considered by some to have long term carcinogenic properties.
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Likewise, the carcinogenic action of bile may be related to the duration of exposure of gastric mucosa to biliary carcinogens.
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The results of experiment had certain significance for revealing anticarcinogenic mechanism of vitamin A aralogs.
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In addition to greenhouse gas reductions, the report looked at new regulations to reduce the release of toxic and carcinogenic emissions such as benzene, a chemical that is released from gas pumps and acrylonitrile, which is used to manufacture synthetic rubber.
Top Stories - Google News
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Recently, it has been suggested that nitric oxide produced during an inflammatory response could become an endogenous cytotoxin, with mutagenic and/or carcinogenic properties.
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Each carcinogenic mixture acts as a unique entity to produce its own specific cancer cluster.
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Long-term carcinogenicity studies have been performed in rats (dosing duration of 104 weeks) and mice (dosing duration of 91 weeks) at doses up to and including 900 mg/kg/day and
Digital50.com Digital 50 Daily Industry News RSS Feed
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Yet, unlike the strict safety evaluations for approval of new drugs, there are no mandatory human clinical trials of GE crops, no tests for carcinogenicity or harm to fetuses, no long term testing for human health risks, no requirement for long-term testing on animals, and limited testing for allergenicity, with some studies PDF raising concerns that GE foods may pose an allergen risk.
Naomi Starkman: Just Label It: We Have a Right to Know What's In Our Food
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Soot and creosote build-up cause foul odors, excessive and carcinogenic smoke and fire danger.
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HECKER, E. (1977) New toxic, irritant, and co-carcinogenic diterpene esters from Euphorbiaceae and Thymelaeaceae.
Chapter 5
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The disease has taken hold after the only treatment - sodium arsenite - was banned because it is carcinogenic.
Times, Sunday Times
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Organic compounds including a number of carcinogenic polycyclic aromatic hydrocarbons are also present in coal dust.
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When they are mixed with products containing nitrates, carcinogenic nitrosamines can be formed.
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In fact, one popular laxative ingredient was taken off the market because scientists found ‘clear evidence of carcinogenic activity’ in laboratory animals exposed to phenolphthalein.
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That's what she needed right now: a bitter lungful of carcinogenic smoke inhaled in memory of her Margie.
GALILEE
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For example, chloroform causes liver cancer in female but not male mice; and though benzol and arsenic are carcinogenic in humans, they ‘are not so in any of the rodent species commonly used in experimental laboratories’.
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The nitrous acid produced later in the reaction chain is toxic, corrosive, mutagenic, teratogenic, and carcinogenic.
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Concerns on the cancer risks of talc, dioxane, formaldehyde, nitrosamine and ethylene oxide, besides other prohibited and restricted carcinogenic ingredients in cosmetics and personal care products, are not new.
Samuel S. Epstein: Multiple Carcinogens in Johnson & Johnson's Baby Shampoo
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It be little toxic and be not carcinogenic, teratogenic . It can be degraded by microbe, and the catabolite is harmless to human , beast and aquatic animal.
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Dr. Hamburg's dismissal of standard carcinogenicity tests is bizarre.
Samuel S. Epstein: Multiple Carcinogens in Johnson & Johnson's Baby Shampoo
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Early reports suggesting an increased risk of carcinogenicity, especially lymphoma, have not been borne out in subsequent studies.
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At least 60 of the chemicals in a puff of smoke are carcinogenic, meaning they may cause cancer.
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Several agricultural innovations like 2,4-D weed spray and diethyl stilbestrol for cattle feeding were banned by federal agencies because of their carcinogenic consequences.
Diffusion of Innovations
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When you grill, fry, or broil meat, it forms carcinogenic compounds.
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The colonic epithelium is in continuous contact with potentially carcinogenic compounds, which enter the body usually as part of the diet.
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The risk of a carcinogenic effect of a substance can be assessed by 1 of several mathematical models.
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These often contain perchloroethylene, the solvent used in dry cleaning, which emits carcinogenic fumes that can make you lightheaded, nauseous, and disoriented.
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Likewise, the carcinogenic action of bile may be related to the duration of exposure of gastric mucosa to biliary carcinogens.
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Vitamin C is an antioxidant, and it also inhibits the formation of carcinogenic nitrosamines from dietary amines and nitrites.
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The second line of defense against avoidable carcinogenic exposures is the reduction or phase-out of toxics in use.
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Tobacco is a sweet smelling product of the aromatic leaves of the Nicotina plant, but contains carcinogenic and highly addictive substances like nicotine, tar and benzene.
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One family of mycotoxins, the aflatoxins, are carcinogenic and immunotoxic and cause growth retardation in animals.
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The synthetic materials used in tampons, such as rayon (bleached by chlorine), contain carcinogenic substances like dioxin, and have been known to cause toxic shock syndrome.
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Fourteen products contained TCEP, a carcinogenic flame retardant on California's Proposition 65 list of cancer-causing chemicals that has been shown to reduce fertility and cause hyperactivity.
Robyn Griggs Lawrence: Toxic Flame Retardants Rampant in Baby Products, New Study Finds
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Dust flowed in them'sanitary, nonirritating, noncarcinogenic, neutral particles of translucent plastic, becoming virtually liquid in the aggregate, and quite slippery.
Split Infinity
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He could only hope any side effects were noncarcinogenic.
The Dig
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Organic compounds including a number of carcinogenic polycyclic aromatic hydrocarbons are also present in coal dust.
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It's gotta be carcinogenic, hallucinogenic, and every kind of "genic" you can think of.
Grouse Diary Entry
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The authors say that cotinine is a poor biomarker of carcinogenic risk.
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It is the carcinogenic compounds in the tar which are the serious hazard to health, and some, but not all, of these compounds are removed by the filters.
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Long term animal studies with both natural and enriched uranium had negative (nine studies) or equivocal (three studies) results for carcinogenicity.
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Among them, ionizing radiation and genotoxic chemicals with carcinogenic potential play an important role.
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Usually, food that was cooked over direct heat from a burning substance, or one that was smoked, could contain carcinogenic material.
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In this study by IARC, other known carcinogenic substances in solid wood were not identified.
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While the CSPI seem pretty cock-sure that aspartame is about as healthy for you as sucking on the devils dick, the FDA doesn't see it that way: "However, the conclusions from this second European Ramazzini Foundation are not consistent with those from the large number of studies on aspartame that have been evaluated by FDA, including five previously conducted negative chronic carcinogenicity studies," Who to believe, the FDA or some advocacy group?
Archive 2007-07-01
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Cooking at very high temperatures can also contribute to the formation of carcinogenic compounds called heterocyclic amines.
Getting the best from beef
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50% of the 170 compounds were judged to be carcinogenic, but some of these might be false positives.
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Report of the Tropical Products Institute, G87, 107 pp. ADOLF, W. and HECKER, E. (1971) Further new diterpene esters from the irritant cocarcinogenic seed oil and latex of the caper spurge.
Chapter 5
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Critics note that novel genes introduced into GM plants could produce proteins that are toxic, allergenic or carcinogenic.
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The results of this carcinogenicity bioassay not only confirm, but also reinforce the first experimental demonstration of aspartame's multipotential carcinogenicity at a dose level close to the acceptable daily intake ADI for humans.
Archive 2007-06-01
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EFSA's panel on Food Additives and Nutrient Sources added to Food (ANS) was asked by the European Commission for its scientific opinion on the results of the long-term carcinogenicity study of rats that were exposed aspartame.
ConfectioneryNews RSS
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It has been recognized as noncarcinogenic by the Environmental Protection Agency, though it's toxic to fish.
A Mystery In Your Lunchbox
