How To Use Blood-brain barrier In A Sentence
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Patients with frequent relapses often exhibit new lesions after enhancement with gadolinium, indicating focal breakdown of the blood-brain barrier.
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Dietary anaplerotic therapy with triheptanoin is used in clinical trials to promote energy production in patients with peripheral and brain Krebs cycle deficit, as its metabolites - C5 ketone bodies - cross the blood-brain barrier.
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Essential oils contain many terpenes, which are rapidly absorbed through the lungs and cross the blood-brain barrier.
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Additionally, the blood-brain barrier in ICH is disrupted and allows molecules, such as glucose, to extravasate from the intravascular to the extracellular space.
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the brain was protected from the large molecules of the virus by the blood-brain barrier
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Additionally, methods for the use, identification and production of an inhibitor that does not substantially cross the blood-brain barrier are also provided.
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Experimental studies have confirmed that folates are highly convulsant if the blood-brain barrier is circumvented.
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On the other hand, aerosolized particles that circumvent the blood-brain barrier might someday serve as delivery vehicles for drugs.
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It is normally protected from chemicals and drugs by the blood-brain barrier, which acts as a filter.
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This agent crosses the blood-brain barrier and thereby reverses both central and peripheral effects of the abused anticholinergic drug.
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Here, using molecular modeling and in vitro and in vivo studies, we show (1) xenon is a tPA inhibitor; (2) intraischemic xenon dose dependently inhibits tPA-induced thrombolysis and subsequent reduction of ischemic brain damage; (3) postischemic xenon virtually suppresses ischemic brain damage and tPA-induced brain hemorrhages and disruption of the blood-brain barrier.
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The clinical manifestations of hypertensive encephalopathy are due to increased cerebral perfusion from the loss of blood-brain barrier integrity, resulting in exudation of fluid into the brain.
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A prerequisite for invasiveness is the ability of pneumococci to transmigrate and to disseminate through the epithelial and endothelial layers and to breach the blood-brain barrier.
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The active transport mechanism for methylfolate across the blood-brain barrier strictly limits the entry of the vitamin, perhaps for reasons concerned with the excitatory properties of folic acid.
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Recent work is again focused on the vascular changes as a basis of the breakdown of the blood-brain barrier that precedes the inflammation and demyelination in a multiple sclerosis plaque.
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The body has lots of different barriers – blood-brain barrier, the skin, the lining of the gut , the placenta – and it may be that this mechanism works in some of these barriers.
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Another herb—red velvet bean plant—is used widely in Indian Ayurvedic medicine and contains L-dopa, which is converted to dopamine once it crosses the blood-brain barrier and might be used to treat Parkinson’s disease in higher doses.
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Aboody and her colleagues were the first to demonstrate in 2000 the inherent propensity of neural stem cells to home in on invasive tumor cells, also known as tropism, even migrating from the opposite side of the brain or across the blood-brain barrier.
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