How To Use Bile acid In A Sentence
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Therefore, the bile acid can also prevent bulge and the abdomen swelling and etc.
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Excessive faecal bile acid losses have not been found in all studies in adult patients with cystic fibrosis.
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The award to Wieland was primarily for his investigations of bile acids, whereas Windaus was recognized mainly for his work on cholesterol and his demonstration of the steroid nature of vitamin D. Wieland had already in 1912, before his prize-winning work, formulated a theory for biological oxidation, according to which removal of hydrogen (dehydrogenation) rather than reaction with oxygen is the dominating process.
The Nobel Prize in Chemistry: The Development of Modern Chemistry
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Total bile acid concentration was calculated as the sum of all gas liquid chromatography detected individual bile acids.
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This was coupled with an increased faecal bile acid concentration and proportion of secondary faecal bile acids.
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This was coupled with an increased faecal bile acid concentration and proportion of secondary faecal bile acids.
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Most cholesterol under normal conditions is manufactured in extrahepatic tissues, and the principal and essential task is to move cholesterol to the liver for excretion as bile acids and unaltered cholesterol.
Statin effects of low-carb diets | The Blog of Michael R. Eades, M.D.
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Our own recent studies have shown an increased proportion of secondary biliary bile acids in patients with colorectal cancer.
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Nevertheless, we propose that the increased concentration of bile acids and increased daily excretion may predispose to the development of polyps.
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Antibiotic associated diarrhoea can also result from a decrease in metabolism of carbohydrates and bile acids.
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Meat-eaters must produce extensive bile acids in their intestines to properly digest the meat that they eat.
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Nevertheless, we propose that the increased concentration of bile acids and increased daily excretion may predispose to the development of polyps.
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Stool frequency and volume decreased and bile acid absorption increased after treatment.
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The clinical efficacy of bile acid therapy was determined in patients with symptomatic radiolucent gallstones smaller than 15 mm within a functioning gallbladder.
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It is thought that the major bile acid binding protein in the cytosol of rat hepatocytes is 3 hydroxysteroid dehydrogenase, a member of the aldo keto reductase supergene family.
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Total bile acid concentration was calculated as the sum of all gas liquid chromatography detected individual bile acids.
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It has been suggested that sequestration of bile acids by intracellular bile acid binding proteins may also protect cells from bile acid cytotoxicity.
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Aim To investigate the role of total bile acid ( TBA ) and uric acid ( UA ) in pathogenesis of essential hypertension.
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The bile acid concentration in faecal water also decreased with increasing dietary calcium, and this was not influenced by dietary phosphate.
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The ultimate fate of bile acids is secretion into the intestine, where they aid in the emulsification of dietary lipids.
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Stool frequency and volume decreased and bile acid absorption increased after treatment.
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The bile acids serve as a vehicle for cholesterol excretion and aid in the digestion of dietary lipids.
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Thus, in cases of repeated heat exposure, having higher than normal bile flow rate, the enterohepatic circulation of bile acids is likely to be broken, since a large fraction would remain unabsorbed in the small intestine.
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Nevertheless, we propose that the increased concentration of bile acids and increased daily excretion may predispose to the development of polyps.
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The downstream methionine metabolite taurine is necessary for amino acid and bile acid conjugation, and acylation reactions.
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Stool frequency and volume decreased and bile acid absorption increased after treatment.
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Cholesterol, bile acids, and phospholipid output concentrations were not significantly altered.
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Cholesterol, bile acids, and phospholipid output concentrations were not significantly altered.
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Our own recent studies have shown an increased proportion of secondary biliary bile acids in patients with colorectal cancer.
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The bile acid concentration in faecal water also decreased with increasing dietary calcium, and this was not influenced by dietary phosphate.
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In the past, many patients were accepted for bile acid treatment without specific, gall stone related symptoms.
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Patients with established colorectal cancer showed increased proportions of secondary bile acids in their faeces.
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With reduced levels of cholesterol, statins also inhibit the synthesis of bile acids.
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The five diseases studied by the CLiC team are: Alagille Syndrome (AGS), Alpha-1-antitrypsin deficiency (a-1AT), Bile acid synthesis and metabolism defects, Mitochondrial hepatopathies, and Progressive familial intrahepatic cholestasis (PFIC).
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Meat-eaters must produce extensive bile acids in their intestines to properly digest the meat that they eat.
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INT-747 is a novel derivative of a human bile acid CDCA (that binds to the farnesoid-X receptor).
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Bile acids are necessary for the absorption of dietary fats and cholesterol from the intestine.
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Invitro studies have shown impairment of bile acid absorption in the ileal mucosa of patients with cystic fibrosis.
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Objective To eliminate the interference of the reagent residual contamination for serum total bile acid ( TBA ) measurement.
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One time oral administration of curcumin, pipeline, coriander, cumin, fenugreek, mustard, asafoetida, ajowan, fennel and onion as a single dose significantly increases bile acid secretion (Table II).
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Cholesterol, bile acids, and phospholipid output concentrations were not significantly altered.
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Meat-eaters must produce extensive bile acids in their intestines to properly digest the meat that they eat.
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Total bile acid concentration was calculated as the sum of all gas liquid chromatography detected individual bile acids.
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In contrast to fatty acids, the total bile acid concentration was hardly influenced by the different diets.
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Conclusion CGRP can promote bile acid reflux in the stomach. CGRP affect and regulate the relaxation function of the pyloric sphincter.
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Not all studies support a direct link between fat malabsorption and faecal bile acid losses.
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Bile acids in the rat are predominantly conjugated with taurine.
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Meat-eaters must produce extensive bile acids in their intestines to properly digest the meat that they eat.
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Similar difficulties arise in the interpretation of another study of polyp patients that showed no differences in faecal bile acid excretion.
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Such diurnal variations may possibly explain why two of the patients showed increased bile acid synthesis but normal SeHCAT values.
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The liver exclusively synthesizes bile acids from cholesterol via two biosynthetic pathways.
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The reduced bile acid absorption is likely to reflect damage to the terminal ileal mucosa.
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INT-747 is a potent, first-in-class farnesoid X receptor (FXR) agonist derived from the primary human bile acid chenodeoxycholic acid (CDCA), the natural endogenous FXR agonist.
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Still one more was first produced by Reichstein by a semisynthetic method from a derivative of bile acid and thus being readily available, it has been a valuable remedy in cases of Addison's disease and certain other cases of reduced function of the cortex.
Nobel Prize in Physiology or Medicine 1950 - Presentation Speech
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The soluble fibre binds to cholesterol and bile acids (which contain cholesterol) in your gut.
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This may cause diarrhoea on account of the possible bile acid malabsorption.
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Animal studies have shown that many spices induce higher secretion of bile acids which play a vital role in fat digestion and absorption.
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Vitamin D and bile acids are steroids.
The Dictionary of Nutritional Health
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The reduced bile acid absorption is likely to reflect damage to the terminal ileal mucosa.
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The cholesterol-lowering medications referred to as bile acid sequestrants (including cholestyramine and colestipol) lower blood levels of carotenoids, including lycopene.
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More than 95% of the bile acids are then reabsorbed, the major portion by active uptake in the distal ileum.
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These findings would suggest that an interplay of various intraluminal factors, including bile acids themselves, may affect colonic function.
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Meat-eaters must produce extensive bile acids in their intestines to properly digest the meat that they eat.
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During pregnancy increased amounts of sex hormones are given off, while in jaundice the bile acids are retained in the body.
Nobel Prize in Physiology or Medicine 1950 - Presentation Speech
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Bile acids and other constituents of bile produced in the liver are carried to the gall bladder via the hepatic and cystic ducts.
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Furthermore, dietary manipulation studies have shown that high fat intake can increase faecal bile acid excretion.
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Cholesterol was added to increase the intestinal concentration of bile acids, because dietary cholesterol stimulates bile acid synthesis in rats.
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This inhibition is caused by the formation of insoluble precipitates of calcium, phosphate, and bile acid micelles.
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The SeHCAT test has made intestinal bile acid malabsorption much more easy to detect.
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In contrast to fatty acids, the total bile acid concentration was hardly influenced by the different diets.
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During his time at UT-Southwestern, Russell has emerged as a scientific leader in elucidating the enzymatic pathways responsible for the metabolic breakdown of cholesterol into other components such as sterol hormones, vitamins and bile acids.
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The bile acids are synthesized as excretory products of cholesterol catabolism and are composed of a carbon-24 steroid nucleus.