How To Use Acellular In A Sentence
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The second module, which we call the adaptation module, is known to maintain the intracellular signal at
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The effects of the structures of the compounds on the insect glutamate potentials were investigated by using electrophysiological intracellular microelectrode recording technique.
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Objective To evaluate the clinical use of acellular dermal matrix ( ADM ) in the repair of pharynx.
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The "extrinsic" pathway involves transmembrane, extracellular receptor-dependent activation of caspase-8 (and possibly -10).
The Scientist
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In 1996, the NVIC realized a major goal when the FDA licensed an improved pertussis vaccine known as the acellular pertussis vaccine.
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This laboratory is equipped with a new intravital microscope system and is interested in the role of intracellular signaling molecules in leukocyte recruitment.
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The extracellular signaling of hormones, light, and odorants is facilitated by a large family of G-protein-coupled receptors.
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In in vitro preparations of partially purified enzymes, the functional distinction between intracellular and extracellular calcium is lost.
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MAb 4C5, while not affecting secretion of the inactive MMPs, inhibits their activation by disrupting their interaction extracellularly with both isoforms of HSP90.
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Damaged endothelial cells secrete p-selectin, e-selectin, intracellular adhesion molecules and vascular cell adhesion molecules that induce monocytes to marginate, roll, and adhere to endothelial surfaces.
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Extracellular osmolal concentration is approximately twice the sodium concentration.
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Calcium currents were isolated by replacing extracellular sodium with TEA and adding tetrodotoxin and other K + channel blockers.
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Modulation of intracellular calcium also affects organelle position and motility.
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Measurement of intracellular daunomycin ( DNR ) and membrane glycoprotein ( P - gp ), by flow cytometry.
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More than 90 per cent of tissue can be such extracellular material.
Times, Sunday Times
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A drop in the intracellular concentration of glutamine provides a signal for the activation of transcription of nitrogen-regulated genes.
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To study allograft acellular dermal matrix in cosmetologty repaire of nasolabial groove soft tissue deficiency.
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Rhococcus equi, a gram-positive bacterium, is a facultative intracellular coccobacillus that causes bronchopneumonia in foals aged 1 to 6 months.
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The bacteria that grew in severely P-depleted and As-enriched conditions were identified as members of a halophile salt-loving family already known to accumulate intracellular As.
Athena Andreadis, Ph.D.: Arsenic and Odd Lace
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These animals are thought to survive only if ice is confined to their body cavity and other extracellular spaces.
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A thin layer of extracellular matrix (perimysium) separating fiber groups within the muscle appears in cross-section.
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Portions of both a and b form the extracellular ligand binding domains.
The Scientist
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If a pressor agent must be used, a direct-acting alpha-adrenergic agonist such as norepinephrine is preferable because it acts without releasing intracellular amines.
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‘Autoxidation’, the authors comment, ‘is a serious problem that limits the storage time for acellular hemoglobin-based blood substitutes.’
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Besides being segmented, the body wall of annelids is characterized by being made up of both circular and longitudinal muscle fibers surrounded by a moist, acellular cuticle that is secreted by an epidermal epithelium.
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The size, shape, and compartmentalization of these specialized cells must be generated and supported by the cytoskeletal systems of intracellular transport.
Another predictable argument against front-loading
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As indicated previously, intracellular calcium is usually an inhibitor of adenylate cyclase, but this is not invariably the case.
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The human stage amastigote is an obligate intracellular parasite, spherical, 2 to 5 g in diameter, and displays a nucleus and kinetoplast.
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In in vitro preparations of partially purified enzymes, the functional distinction between intracellular and extracellular calcium is lost.
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Some procedures supply immediate gratification, such as zapping away brown spots or erasing lines, and some can provide long-term antiaging results by growing more collagen and invigorating the extracellular matrix.
Simple Skin Beauty
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Hexavalent vaccines such as diphtheria, tetanus, acellular pertussis vaccine, hepatitis B virus vaccine, IPV, and Hib are being developed.
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Treh-1 is a cytosolic enzyme involved in the hydrolysis of endogenous trehalose, while Treh-2 is an extracellular enzyme proposed to have a role in the assimilation of exogenous trehalose as a carbon source
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The potential involvement of extracellular histones in atherogenesis may be envisaged through several routes.
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In intact cells the probe was trapped both inside intracellular organelles and the cytoplasm.
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Subsequently, when zeolite is chemically dissolved in a simple water solution, or when taken as a straight mineral supplement in capsule form, its therapeutic effect (i.e. benefit to you) is not as strong or beneficial as it is when combined with an all natural, organic, bio-active intracellular carrier such as humic, fulvic, or processed humates.
Wil's Ebay E-Store
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Microscopic examination revealed nests and cords of clear cells separated by a fibrous and acellular mucoid stroma.
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The extracellular matrix is a complex mixture containing proteins such as fibronectin and collagen that provide structural support to cells and traction for cell movement.
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FDA can pass through the cell membrane whereupon intracellular esterases cleave off the diacetate group.
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Conclusion: Acellular dermal matrix is a ideal graft material for soft tissue augmentation.
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Integrin is the molecule that connects the outside of the cells to the extracellular matrix.
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New versions of existing vaccines: acellular pertussis vaccine (DTaP - 1997); intranasal influenza (2004)
History of Vaccine Schedule
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In the present study, no association was found between the use of extracellular preservation fluid and early gas exchange.
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Similarly, homeostatic mechanisms that regulate the extracellular environment may be affected by characteristics of the cell surface.
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The Anion Hypothesis There are certain organic anions present in the axoplasm of a neuron but absent from the extracellular fl uid.
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In some areas, particularly those close to the surface of the tumors, the eosinophilic extracellular material resembled fibrinoid necrosis and showed associated areas of organization consistent with typical granulation tissue.
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It is caused by the bacterium Lawsonia intracellularis, and is more accurately described as regional enteritis or proliferative ileitis .
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Journal of Cell Biology reveals that an extracellular matrix protein called laminin shapes both sides of the junction to ensure they fit together.
Health News from Medical News Today
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After resuspension in 1 mM chloride extracellular medium, cells were isolated by gentle trituration.
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The temperature of platelet intracellular ice crystal formation (IIF) is one of the most important physical parameters to instruct platelet cryopreservation.
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We collaborated with my good friend William Sleator of the Physiology Department in the study of changes in cellular action potentials (measured with intracellular microelectrodes) associated with the changes in contractility of the guinea pig atrium in response to epinephrine and acetylcholine, and a number of other inotropic agents.
Robert F. Furchgott - Autobiography
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The virus increases the risk of cancer by interfering with two vital intracellular processes: reproduction and repair.
Times, Sunday Times
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The residues crucial for transport and pathogenicity are nucleated in two groups: one around the central channel, and the other on the long intracellular loop.
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Fluid inside your cells is called intracellular fluid and the fluid outside your cells is called extracellular fluid.
The Most Complete Food Counter, 2nd Edition
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On the extracellular side of the membrane, a small extracellular domain is composed of short loops between various transmembrane helices and contains the binding site for ouabain.
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1992 – Acousto-conformational transitions in cytoskeletal microtubules: Implications for intracellular information processing
Behe vs. Dawkins
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One factor that isn't mentioned explicitly in the article is the use since 1996 of the acellular pertussis vaccine instead of the whole cell vaccine.
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Recently the intracellular protein BAT3, which is involved in DNA damage induced apoptosis, was identified as a ligand for NKp30.
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intracellular fluid
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One was obviously to further dissect the tyrosine aminotransferase (TAT) ATP-dependent proteolytic pathway: Avram started his own trip into the world of intracellular proteolysis with Gordon and discovered that the degradation of the gluconeogenetic enzyme TAT in cells requires energy.
Aaron Ciechanover - Autobiography
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Calcium ions as mediators of intracellular signalling are crucial for development of apoptosis.
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Fragments of metachromatic chondromyxoid extracellular material contained cells that were reminiscent of chondrocytes.
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All cholesterol assays measure the total cell cholesterol, so it is not possible to distinguish between plasma membrane cholesterol and intracellular cholesterol.
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Fluid inside your cells is called intracellular fluid and the fluid outside your cells is called extracellular fluid.
The Most Complete Food Counter, 2nd Edition
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On the inner surface of the cell layer, a basal lamina (an organized layer of extracellular matrix) is laid down.
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One possible, straightforward interpretation of these results would be that the current rising phase is related to electrogenic chloride binding from the extracellular side induced by GABA to the transporter.
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Among them, one of the most studied is the anaplerotic utilisation of intracellular carbon sources through the glyoxylate shunt enzyme ICL icl gene after M. tuberculosis infection of macrophages and dendritic cells
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Similarly, all genera have some sort of anterior conoid like structure associated with predation or intracellular insertion in the Apicomplexa.
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Status of various immune cells and intracellular secretion of cytokines were assessed by flow cytometry.
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When present, the annelid peritoneum either rests directly on the muscle cells or is separated from them by a layer of extracellular matrix.
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There is indeed direct evidence that mechanical stress can generate intracellular signals that regulate gene expression.
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It may be difficult to rule out hypomagnesemia as the cause of or a contributor to hypocalcemia because the serum magnesium level may be normal, even when intracellular magnesium stores are reduced.
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Microsporidia are obligate intracellular parasites that were thought to be an ancient eukaryotic lineage based on molecular phylogenies using ribosomal RNA and translation elongation factors.
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Blood obtained from a skin puncture is a mixture of arterioles, venules and capillaries and contains interstitial and intracellular fluids.
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At the junction of the flowing blood and extracellular space, the endothelium is a dynamic organ that modulates local hemostasis, cell trafficking, and microcirculatory blood flow.
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Additionally, there will be an increased renal excretion of potassium causing a decrease of potassium in the extracellular fluid. 258.
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During seizures, there was a sustained increase in extracellular glutamate to potentially neurotoxic concentrations in the epileptogenic hippocampus.
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It is advisable to use a direct-acting alpha-adrenergic agonist, such as norepinephrine, because their actions are not dependent upon the release of intracellular amines, the metabolism and availability of which are altered by MAO-I's.
Monamine Oxidase Inhibitors
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Exactly how receptor auto-phosphorylation alters receptor affinity is not yet known, although both linkage and cooperativity require the presence of the intracellular juxtamembrane domain as deletion of this region eliminates both binding phenomena.
Journal of Biological Chemistry current issue
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Integrins are an ancient group of animal adhesion receptors that attach cells to the extracellular matrix.
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Mycobacterium intracellulare, a species of the Mycobacterium avium complex, may be the cause of severe lung, lymphatic node, skin and bone/joint infections, as well as bacteriemia.
BioMed Central - Latest articles
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The progenitor cell loses its nucleus, and most of its intracellular membranes are degraded; the now non-nucleated form of the cell, termed a reticulocyte, then loses its ribosomes, thus preventing any further synthesis of haemoglobin.
Conservapedia - Recent changes [en]
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In at least two, widely divergent systems, electron-dense extracellular tubules have been observed surrounding developing spores during sporogony.
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That powder is a substance made from pig bladders called extracellular matrix.
March « 2008 « Gerry Canavan
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A systems analysis by Bayesian networks further showed that the number, size, concentration of cargo and intracellular position of endosomes are not determined randomly but are subject to specific regulation, thus uncovering novel properties of the endocytic system.
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Uroisolate PU7, was found to elicit the maximum virulence factors elaborating extracellular enzymes, protease, elastase, phospholipase C, haemolysin and pyochelin.
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He worked on production of Adenosine tri phosphate (ATP), the multifunctional nucleotide involved in intracellular energy transfer, from Nicotinamide adenine dinucleotide (NAD), and Nicotinamide adenine dinucleotide phosphate (NADP) which plays key role as a carrier of electron and participate in redox reaction.
Prof. Arthur Kornberg, Nobel laureate, died on Sunday, October 26, 2007
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The key to making the discovery was the development of new techniques that allow monosynaptic connections between pairs of cells to be examined with dual intracellular recordings.
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The cell wall and extracellular material are often only crudely preserved in this process, and the internal cytoplasm may degrade and be destroyed.
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We also detected increases in fragments of intracellular structural proteins: tubulin, actin, and myosin.
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DNA and the intracellular machinery share engineering techniques employed by intelligent entities, therefore until demonstrated otherwise, they should be considered to be intelligently designed.
Attached to Strings
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Strategies that allow plants to survive freezing temperatures have been placed into two major categories: those plants that exhibit deep supercooling characteristics and those that exhibit extracellular freezing.
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Correction: An earlier version of this article incorrectly referred to autophagy as intercellular housecleaning; it should have been intracellular housecleaning.
NYT > Home Page
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High levels of intracellular calcium allow calmodulin to activate the myosin light chain kinase that facilitates muscle contraction.
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He was an early champion for the introduction of safer whooping cough vaccines, called acellular vaccines.
Undefined
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If the smear shows Gram negative intracellular diplococci, the patient is treated for gonorrhoea and chlamydia to cover the possibility of a mixed infection.
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It should be possible to test this by observing chromosome behavior in the spindles of dividing animal cells while artificially raising the concentration of intracellular calcium during prometaphase or blocking its rise at the beginning of anaphase.
ID-friendly journal paper makes testable predictions
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They are stored within the basal membrane or extracellular matric and released in an active form to stimulate tissue repair and healing.
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One-quarter of this extracellular fluid is contained within blood vessels as the plasma space.
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The first module, which we call the receptor module, detects changes in environmental conditions to generate an intracellular signal.
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This absence of effects is in line with the data from Fig.2, and confirmed that the intracellular and extracellular concentrations of Cl were truly equilibrated.
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Such infections would include viral and intracellular bacterial infections.
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Some antibiotics, such as azithromycin and clarithromycin, concentrate intracellularly, not in middle ear fluid, and are bacteriostatic, not bactericidal.
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The bone tissue of well-preserved individuals reveals some regions that are acellular adjacent to areas that are highly cellular, and other areas where masses of Sharpey's fibers are adjacent to areas where none exist.
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There is indeed direct evidence that mechanical stress can generate intracellular signals that regulate gene expression.
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The team began building their test-tube immune system by adding RIG-I, the intracellular fluid known as cytosol, and the power-producing organelles called mitochondria.
HHMI News
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Initial therapy of patients with large tumor masses has been complicated by large releases of intracellular potassium with resultant refractory hyperkalemia.
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We showed that the positive inotropic effects of norepinephrine and strophanthin-K were correlated with an increase in rate of exchange of calcium in an intracellular pool associated with the contractile process and that the negative inotropic effects of acetylcholine and adenosine were correlated with a decrease in rate of exchange in that pool.
Robert F. Furchgott - Autobiography
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It is through its regulation of intracellular calcium that InsP 3 functions to regulate so many cellular processes.
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It is possible that depolarization forces internal polyamines through the pore, where they might accumulate in an unstirred extracellular space, blocking the channel during the measurement of inward conductance.
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This suggests that platelets must possess very sophisticated intracellular control mechanisms.
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Briefly, a cell volume distribution was obtained and gates were set to select for counting only intact cells excluding acellular debris.
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The capillary grows by degradation of the extracellular matrix and proliferation of cells at the tip of the sprout.
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CMV pneumonitis was defined purely on a histologic basis by the presence of typical cytomegalic cells with characteristic intracellular inclusions or positive immunolabeling with a CMV-specific antibody.
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Taken together, our analysis provides strong evidence for a reductive mode of evolution in obligate intracellular parasites with high rates of DNA loss.
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Chemokines bind heparin and other glycosaminoglycans of the extracellular matrix of cells, which helps establish and maintain a chemokine gradient.
The Scientist
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Anabolic agents also improve intracellular reutilization of amino acids so that nitrogen is retained in the body rather than excreted.
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If your main interest is clinical an explanation of intracellular recordings and autoradiography will be welcome, and presumably scientists will have a similar view about the clinical sections.
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For intracellular measurements the probe is commonly a glass micropipette that has been back-filled with a salt-solution and has a tip diameter suitable for insertion into a plant cell.
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It is through its regulation of intracellular calcium that InsP 3 functions to regulate so many cellular processes.
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It can be readily seen that sodium is the principal extracellular cation and that chloride and bicarbonate are the principal extracellular anions.
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Among them, one of the most studied is the anaplerotic utilisation of intracellular carbon sources through the glyoxylate shunt enzyme ICL icl gene after M. tuberculosis infection of macrophages and dendritic cells
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During catabolic stress intracellular glutamine levels can drop more than 50 percent, and it is under these circumstances that supplemental glutamine becomes necessary.
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OBJECTIVE: A prospective randomized unblinded controlled trial was conducted by comparing acellular dermis with temporalis fascia as graft materials in tympanoplasty (type 1) in terms of operative time, postoperative pain, graft success rate, and audiologic outcome.
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It can be readily seen that sodium is the principal extracellular cation and that chloride and bicarbonate are the principal extracellular anions.
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Magnesium is the fourth most abundant cation in the body and is second only to potassium in intracellular concentration.
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The additional membrane is provided by intracellular vesicles, which fuse with the plasma membrane.
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Moreover, for a number of cell types and extracellular matrix molecules, cell speed exhibits a biphasic behavior with respect to surface ligand density.
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These results suggest that the spasmolytic and vasodilator effects of Mc. Cr root extract are mediated possibly through blockade of voltage-dependent calcium channels and release of intracellular calcium, which may explain the medicinal use of Morinda citrifolia in diarrhea and hypertension.
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Objective To establish an expression system of human II CD74 extracellular fragment by insect baculovirus vector expression system in insect cells.
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Proteasomes are large complexes of enzymes that break down intracellular proteins, recognizing them by their ubiquitin molecular tags.
The Scientist
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Paul M, Durand R, Boulard Y, Fusai T, Fernandez C, et al. (1998) Physicochemical characteristics of pentamidine-loaded polymethacrylate nanoparticles: implication in the intracellular drug release in Leishmania major infected mice.
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Magnesium is the fourth most abundant cation in the body and is second only to potassium in intracellular concentration.
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Histological examination Day 3: The biopsies showed moderate to severe inter and intracellular oedema.
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Others included those for diphtheria, tetanus, acellular pertussis and meningitis.
Times, Sunday Times
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As the technology advances, it may prove to be a key factor in unlocking the molecular-level secrets of intracellular dynamics, said Davidson, who directs the magnet lab’s Optical Microscopy Group.
Revolutionary Microscope Developed | Impact Lab
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At the junction of the flowing blood and extracellular space, the endothelium is a dynamic organ that modulates local hemostasis, cell trafficking, and microcirculatory blood flow.
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Translation takes place in embryonic mesoblasts and larval fat-body cells and is deposited extracellularly in basement membranes surrounding skeletal and visceral muscles.
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The helices have a radial slope and converge at the intracellular bundle narrowing.
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A newer version of the vaccine, called the acellular pertussis vaccine, contains fewer pertussis proteins and causes fewer reactions.
Global Immunization: Vaccine Coverage is Variable
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Gas vesicles are gas-filled intracellular structures that provide buoyancy in many unicellular aquatic organisms.
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In 1996 a new ( "acellular") pertussis vaccine was available for use in the United States.
Vaccine Safety FAQs
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The new "acellular" pertussis vaccine had a much lower risk of severe side effects than the old "whole-cell" vaccine.
Vaccine Safety FAQs
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The intracellular expression of TLR3 and type I IFN inducible myxovirus resistance protein A (MxA) protein as well as the level of apoptosis were analyzed by flow cytometry.
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Chemokines bind heparin and other glycosaminoglycans of the extracellular matrix of cells, which helps establish and maintain a chemokine gradient.
The Scientist
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Extracellular osmolal concentration is approximately twice the sodium concentration.
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We are currently investigating if, similar to hNSCs, also T-IhNSCs can be induced to generate catecholaminergic cells by exposure to specific extracellular cues
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In our body, the cells in each of these organs sit in a fibrous extracellular matrix.
Times, Sunday Times
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The mesoderm also provides the mesenchyme (by sinking of cells from its epithelium into the extracellular matrix) from which organ development becomes possible.
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The way in which rickettsiae use the KAP NTPases in the intracellular host cell environments has not yet been investigated but several members of this family, namely the AAA+ ATPases were described to promote virulence of other bacterial pathogens
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Liver fibrosis and cirrhosis, characterized by the excessive production and decreased degradation of abnormal extracellular matrix, are a major cause of morbidity and mortality in biliary atresia.
Basic Science Liver Disease Research
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73, 279-285 (1976) [31] Risteli, J.; Tuderman, L.; Kivirikko, K.I.: Intracellular enzymes of collagen biosynthesis in rat liver as a function of age and in hepatic injury induced by dimethylnitrosamine.
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These intracellular stages include an asynchronous mixture of both first- and second-generation meronts and merozoites, as well as some gametocytes and gametes.
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These toxins can remain inside algal cells (intracellular toxins), or they may be released into the surrounding water (extracellular toxins) during active algal growth or when algal cells lyse.
Inorganic nitrogen pollution in aquatic ecosystems~ causes and consequences
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The extracellular medium was redissolved in deionized water and extracellular polymers were precipitated by adding ethanol to reach a final concentration of 80%.
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The viral RNA challenge falls short because the genomes of such viruses do decay in extracellular environments.
Another Protozoan and Front-Loading
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The Sec24CD dependent COPII vesicles, thus, carry cuticle components as diverse as for example the chitin synthase producing the bulk of the procuticle, factors of the extracellular melanisation pathway, and the yet unknown lipid-handling enzymes of the envelope and epicuticle.
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In a Swedish fjord sediment where G. pseudospinescens is the dominant foraminifer, the intracellular nitrate pool in this species accounted for 20% of the large, cell-bound, nitrate pool present in an oxygen-free zone.
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The short answer is: an extracellular matrix composed of collagen, proteoglycans, adhesive glycoproteins, and integrin.
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Ligand-competitive binding of antibodies was measured by Notch1 extracellular domain (ECD) displacement in a dissociation-enhanced time resolved fluorometric assay (DELFIA).
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the body normally has about 15 quarts of extracellular fluid
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One was obviously to further dissect the tyrosine aminotransferase (TAT) ATP-dependent proteolytic pathway: Avram started his own trip into the world of intracellular proteolysis with Gordon and discovered that the degradation of the gluconeogenetic enzyme TAT in cells requires energy.
Aaron Ciechanover - Autobiography
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As the channel opens upon a depolarization, the trapped ion can escape to the intracellular medium increasing the stability of the bound toxin.
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Certain cells, such as fibroblasts - cells responsible for producing extracellular matrix in wound healing and tissue remodelling - will migrate along the tracks.
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However, filopodial protrusions would be more efficient for crawling through extracellular matrix and on surfaces of other cells.
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As the electrolytes shift out of the cells, fluid shifts into the cells so that the tonicity matches that of the extracellular space.
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As for the intracellular end, interestingly, the horn-shaped pathway incurvates so that its exit is located almost to the side of the protein.
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Indeed, recent evidence indicates that endocannabinoids influence the intracellular events controlling the proliferation of numerous types of endocrine and related cancer cells, thereby leading to both in vitro and in vivo antitumour effects.
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Histopathologic examination of the biopsy tissue showed a granular, relatively acellular material filling the alveolar spaces diffusely.
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Dentin is a complex mixture of extracellular matrix proteins, of which 90 percent is collagen.
The Scientist
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The mesoderm also provides the mesenchyme (by sinking of cells from its epithelium into the extracellular matrix) from which organ development becomes possible.
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After peripheral nerve injuries, Schwann cells play an indispensable role in promoting regeneration by elaborating basement membrane containing extracellular matrix proteins, such as laminin
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Intracellular accumulation of such large amount of Cr may disturb the normal functioning of the bacterial cell.
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The controversy over the Pertussis vaccine resulted in the development of a weaker acellular vaccine (not containing whole cells of the pathogen), which is being introduced into many western countries.
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For this reason, viruses are called obligate intracellular parasites.
CreationWiki - Recent changes [en]
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Fully conscious of the insuperable difficulties of explaining at present the innermost mechanism by which this inertness was overcome, Warburg decided to investigate the nature of the mysterious substance that acts as the primus motor in intracellular combustion.
Physiology or Medicine 1931 - Presentation Speech
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It has been suggested that sequestration of bile acids by intracellular bile acid binding proteins may also protect cells from bile acid cytotoxicity.
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Direct-acting pressors have their action extracellularly at postsynaptic receptors. 4 The evaluation of liver function at initial presentation andfour tosix weeks following recovery is recommended, although the incidence of hepatotoxicity following acute overdose is rare. 5 Caution should be exercised in the use of sedative/hypnotics for CNS excitation because of synergistic depressant effects during overdose.
Monamine Oxidase Inhibitors
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Functions encoded by the operon appear to be essential for the phagosomal escape and intracellular growth, since disruptions or deletions of FPI encoded genes of the low virulent strains
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Digital image processing of intracellular pH in gastric oxyntic and chief cells," Nature 325, 447 – 450 (1987).
Roger Y. Tsien - Autobiography
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Both are presumed to be consequences of cell death, and the subsequent leakage of cell contents into the extracellular space.
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After invasion, at 48 hours postinfection, we observed a reduction in the numbers of ysaV transcripts, coincident with the establishment of the intracellular stage of infection.
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In poliovirus infection, both intracellular movement and release of virus appear to be related to cytoskeletal changes, particularly involving actin microfilaments.
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Elements that had been located within the protoplasts (intracellular fraction) were solubilized by digestion with concentrated nitric acid.
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Histologic studies have revealed altered fiber structure, increased vascularity, and changes in the extracellular matrix in patients with chronically painful Achilles tendons.
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Digital image processing of intracellular pH in gastric oxyntic and chief cells," Nature 325, 447 – 450 (1987).
Roger Y. Tsien - Autobiography
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Spiller DG, Giles RV, Grzybowski J, Tidd DM, Clark RE (1998) Improving the intracellular delivery and molecular efficacy of antisense oligonucleotides in chronic myeloid leukemia cells: a comparison of streptolysin-O permeabilization, electroporation, and lipophilic conjugation.
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Proteins may bind to intracellular scaffolds to optimize signal transduction.
The Scientist
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Proteasomes are large complexes of enzymes that break down intracellular proteins, recognizing them by their ubiquitin molecular tags.
The Scientist
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Coronal histological sections of the frontoparietal dome of an adult Pachycephalosaurus wyomingensis reveal a dense structure composed of metaplastic bone with a variety of extremely fibrous and acellular tissue.
ScienceBlogs Channel : Life Science
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Multimeric molecules may also be organized into supramolecular structures presenting discrete adhesion domains within the extracellular environment.
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To prevent intracellular havoc, the fusion of membranes within cells must be highly regulated.
The Scientist
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In addition to the spindle cells, abundant strongly eosinophilic, stellate, extracellular matrix deposits composed of crystalline fibers were seen.
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The tumor cells were arranged in nests, with adjacent acellular myxoid areas.
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Instead, water distribution will be determined by the relative allocation of solute to the extracellular and intracellular spaces.
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The bacteria that grew in severely P-depleted and As-enriched conditions were identified as members of a halophile salt-loving family already known to accumulate intracellular As. When deprived of P, they grew slowly and looked bloated because they were full of vacuoles, cellular organelles that manage waste and grow larger and more numerous when cells are under stress.
Athena Andreadis, Ph.D.: Arsenic and Odd Lace
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Fine-needle aspiration cytology is mostly inconclusive because the tumor is composed of acellular and hypercellular portions.
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Current research suggests that, during the final stages of wound healing, myofibroblasts, again, generally identified by [alpha] smooth muscle actin expression, die through apoptosis to leave an acellular scar.
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Validation studies suggest the technology, called intracellular drug delivery (IDD) discovery platform, can successfully predict membrane penetration.
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The importance of the nucleosome in gene regulation is supported by the finding that mutations that alter intracellular levels of histones lead to transcriptional derepression of a variety of genes.
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The "extrinsic" pathway involves transmembrane, extracellular receptor-dependent activation of caspase-8 (and possibly -10).
The Scientist
