difficulty synonyms

care pressure charge responsibility weight worry stress burden anxiety strain depression distress misery oppression irritation harassment annoyance strife grievance aggravation ado millstone discouragement bafflement to-do exigency

problem trouble bar pass corner check challenge trial crisis hole struggle emergency bother mess frustration embarrassment disadvantage dilemma squeeze hazard plight rub knot hardship paradox obstacle puzzle pinch obstruction maze inconvenience setback misfortune predicament scrape complication hitch straits swamp deadlock muddle standstill labyrinth snag crux slough impasse adversity hindrance impediment barricade perplexity entanglement quandary quagmire quicksand poser rigor imbroglio stumbling block blind alley vicissitude dead end stone wall double bind